Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name PDCL2P2
Wait
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:65160193-65160382  UCSC
Coordinates (T2T) chr11:65153487-65153676  UCSC
Coordinates (hg19) chr11:64927664-64927853  UCSC
Strand -
Parental Sequence NM_024065.5
Parental seq. overlap 176 bp
Parental seq. overlap (%) 17%
Genomic Region Intergenic
Retrocopy Summary PDCL2P2, located on chr11:65160193-65160382, is a retrocopy of the parental gene PDCL3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PDCL3
Full Name phosducin like 3
Also known as HTPHLP|PHLP2A|PHLP3|VIAF|VIAF1
Coordinate chr2:100562993-100577472
Strand +
Gene summary This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PDCL3P7
Bonobo Pan paniscus PDCL3P7
Gorilla Gorilla gorilla PDCL3P7
Orangutan Pongo abelii PDCL3P6
Gibbon Nomascus leucogenys PDCL3P1
Green monkey Chlorocebus sabaeus PDCL3P1
Crab-eating macaque Macaca fascicularis PDCL3P8
Rhesus Macaca mulatta PDCL3P8
Baboon Papio anubis PDCL3P8
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.20.40.6
log10(TPM+1)

Related Sequence

>PDCL2P2
GTGAAAACATATGAAGATATGAATTTGGAAGAGCTGGAGGATCATGTAGACGAATTTGATGAGGAGGATGAACATGCCATTGAAATGTACAGACAGCAGAGACTGGCTGAGTGGAAAGCAACTAAACTGAATAATAAATTTGGAGAAGTTTTGATGATCTCAGGAAAGGATTATGTTCAAGAAGTTACCT
>NM_024065.5
GCGCGTGCACAAAAGAGAGCTGAGGGGCGGGGGCGCTGCGGCACAGCTGGTTTGAGCAACTGAACTGGAAACAAGATGCAGGACCCCAACGCAGACACTGAATGGAATGACATCTTACGCAAAAAGGGTATCTTACCCCCCAAGGAAAGTCTGAAAGAATTGGAAGAGGAGGCAGAAGAGGAGCAGCGCATCCTCCAGCAGTCAGTGGTGAAAACATATGAAGATATGACTTTGGAAGAGCTGGAGGATCATGAAGACGAGTTTAATGAGGAGGATGAACGTGCTATTGAAATGTACAGACGGCGGAGACTGGCTGAGTGGAAAGCAACTAAACTGAAGAATAAATTCGGAGAAGTTTTGGAGATCTCAGGGAAGGATTATGTTCAAGAAGTTACCAAAGCTGGCGAGGGCTTGTGGGTCATCTTGCACCTTTACAAACAAGGAATTCCCCTCTGTGCCCTGATAAATCAGCACCTCAGTGGACTTGCCAGGAAGTTTCCTGATGTCAAATTTATCAAAGCCATTTCAACAACCTGCATACCCAATTATCCTGATAGGAATCTGCCCACGATATTTGTTTACCTGGAAGGAGATATCAAGGCTCAGTTTATTGGTCCTCTGGTGTTTGGCGGCATGAACCTGACAAGAGATGAGTTGGAATGGAAACTGTCTGAATCTGGAGCAATTATGACAGACCTGGAGGAAAACCCTAAGAAGCCGATTGAAGACGTGTTGCTGTCCTCAGTGCGGCGCTCTGTCCTCATGAAGAGGGACAGCGATTCCGAGGGTGACTGAGGCTACAGCTTCTATCACATGCCGAACTTTCTTGTGACAAATTGTCTGGATTTTTTAAAAAAGGAAAAAGCAAGAATGAATCCTTGTGGTTTTTAGTTTTGTATAAATTATGTTTCAAATCTTTACATTTTGGAAATAATCATTGCTGGAGATTCTGTTAAATATTTTGGAACTCTTTTTTTTTTTAAATTATAGTATTTCCTCTAAAAAAAATTAAAACCAGCCATTTGTATGGCAAATGTC

Publications

PMID - Link Title