Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CA14P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:165708186-165709956  UCSC
Coordinates (T2T) chr1:165054582-165056350  UCSC
Coordinates (hg19) chr1:165677423-165679193  UCSC
Strand +
Parental Sequence XM_005245059.3
Parental seq. overlap 1271 bp
Parental seq. overlap (%) 40.5%
Genomic Region Intergenic
Retrocopy Summary CA14P1, located on chr1:165708186-165709956, is a retrocopy of the parental gene CA14. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CA14
Full Name carbonic anhydrase 14
Also known as CAXiV
Coordinate chr1:150257258-150265862
Strand +
Gene summary Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CA14P1
Bonobo Pan paniscus CA14P1
Gorilla Gorilla gorilla CA14P1
Orangutan Pongo abelii CA14P1
Gibbon Nomascus leucogenys CA14P1
Green monkey Chlorocebus sabaeus CA14P1
Crab-eating macaque Macaca fascicularis CA14P1
Rhesus Macaca mulatta CA14P1
Baboon Papio anubis CA14P1
Golden snub-nosed monkey Rhinopithecus roxellana CA14P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CA14P1
AGTCATCTAGTCTCCAAACTCCCAGTCCCCTGTGCCCCTTCCTGGGATACCATGTTGTTCTTCATCCTCCTGCTAGAGGTGATTTGGATCCTGGCTGCAGACGAGGGTCAACACTGGACATATGAGTGCCCACATAGTCAGGACCACTGTGGCCAGCCTTTTACCCTGAGTGTGGAAACAATACACAGTCCCCCTTCGATATCCGGACAGACAGTGTGACAATTGACCCTTAGATGACTGCTCTACAGCCCCATGGATATGACCGGCCTGGCACTGAGCCTTTAGACCTGCACAAGAATAGCTACACAGTACAACTGTCTCTGCCCTCTACCCTGTATCTAGGTGGACTTTCCAGAAAATATGTAGCTACCCAGCTACACCTGCACTGGGGTCAGGATGATCCCCAGGGGGCTCAGAACACCAGATCAACAGTGAAGCCACAGTTGCCGAGCTCCACATCATACGTTATGGCTGTGATTCCTGTGATAGCTTGAGTGAGGCCGCTCAGAGGCCTCAGGGCCTGACTGTCCTGGGCATCCTAATTGAGGTGAGTGAGACTAAGAATATAGCTTATGTGTAGCTTATGAACACATTCTGGGTCACTTGCATGAAATCAAGCATAAAGATCAGAAGACCTCAGTGAGAGAGCTGCTCCCCCGACAGCTAGGGCAGTTCTTCCTTTACAATAGCTCGCTCACAACTTCCCCTTGTTAGTAGAGGGTGCCCTGGACAGTTTTCAGTCCAAGGGCCCAGATTTCAATGGAACGGCTGGAAAAGCTTCAGGAGACATTGTTCTCCACAGAAGAGGGGCCCTCCAAGTCCTGATACAGAACTACTGATCCCCTCAGCCTCTCAACCAGCAATGACCTTTGCTTTTTTCATCCAGATGGGATCCTTGTATCCTACAGGTGAAATGCTGAGCCTTGGTGTAGGAATCTTGGTTGGCTCTCTCTGACTTCTGCTGGCCATTTTCTTCATGGCTAGAAGGCTTCAGAACAAGAGGCTGGAAAATCAGAAGAGCGTGGTCATCACCTCAGCATGAGCCACCACTGAGGCATAAACTCCCTCTTAGATACCTTGGATATGGATGCCTTCCCCTCGTGCCTCCAGAGGTGCTTTCCCCTCATGTCTCACCACCCCTCAGGGAACCTCTAAAATGGGGTGCAGGGACTGGCCGGAATTACTGTAGGAGTAGTAGGCGCTTCTCCTCTGGACATCCCCTGCAGAGAGGTATGGACCCAGGCTCTCATTCAAGGAAGAACAGCAGAGCCTTCAGCCCCTCAAAACATGTAGGAGGAGATCAGGGCATCCCTGTGTTGTTAGTGCAGAGGACAAACTGTGTTTAGTTTTAGGGGAAGTTTGGGATGTACCCCAAAGTCCTCCACCATCTCACCTTTATGTCCCTTTCCCTAGATATATTGCAGGATCTCCCCTTAGGAGAAAGAGTTGCTGTTGGGGTTATATATTTTTGCTCAACATATTTGGAAACTAAAGTTTC
>XM_005245059.3
ACAGAAGAGATTGCTCCAGATGAGTTCTCCTTGCCTCACTTCTCTTCCTTAGAACTTAGGACACAACTCAGGTTTTAGTTATTGACTTCCTCCACCCCTCCCCTGCACCCTGAGTCCCTAATTCCTTCTTGTTATATATCTCCTAATTCTGGACTCTTCCCATTCCAGGGCAGCTCAGATTATGCAGGGAATTGGGAACAGGTACCCCCACCATCTGCCGCATACCACCCAGGGAGCTGCTCCTCAGAGGAGAAATCAGGCGGGGGGATGAAAATACAGTGTCCTTTTGAGGGGGCTGAGTTGAACCCCAAAGCCCCTTCCTTGACCCTGCCTGCTCCAGGGAACACCCATCTAAACAGCATCTGTGTGACTAGCAGAGGAAGGAAGAGCTCACCCCAGCTGGGCTCCTGAGCCAGGGCCAGGGCTCCAGTGAAACTTGCCGCGCTCCAGCTCCGAGTGGGGCCATCCTGCATGCCTAATTGGCTATTTAAGGAGCTGTTCACCAGCAGCCCAGGCAGCACCCCCGTCCCCACATACACCAGTTCAGAGCCACCTTAAAAGCAGGAGGCAGTTGTAAAGTCGCTGGCCAGCTAGTGGAGTGGAGACTGCAGAGGGAGATAAAGAGAGAGGGCAAAGAGGCAGCAAGAGATTTGTCCTGGGGATCCAGAAACCCATGATACCCTACTGAACACCGAATCCCCTGGAAGCCCacagagacagagacagcaagagaagcagagataaatacaCTCACGCCAGGAGctcgctcgctctctctctctctctctcactcctccctccctctctctctGCCTGTCCTAGTCCTCTAGTCCTCAAATTCCCAGTCCCCTGCACCCCTTCCTGGGACACTATGTTGTTCTCCGCCCTCCTGCTGGAGGTGATTTGGATCCTGGCTGCAGATGGGGGTCAACACTGGACGTATGAGGGCCCACATGGTCAGGACCATTGGCCAGCCTCTTACCCTGAGTGTGGAAACAATGCCCAGTCGCCCATCGATATTCAGACAGACAGTGTGACATTTGACCCTGATTTGCCTGCTCTGCAGCCCCACGGATATGACCAGCCTGGCACCGAGCCTTTGGACCTGCACAACAATGGCCACACAGTGCAACTCTCTCTGCCCTCTACCCTGTATCTGGGTGGACTTCCCCGAAAATATGTAGCTGCCCAGCTCCACCTGCACTGGGGTCAGAAAGGATCCCCAGGGGGGTCAGAACACCAGATCAACAGTGAAGCCACATTTGCAGAGCTCCACATTGTACATTATGACTCTGATTCCTATGACAGCTTGAGTGAGGCTGCTGAGAGGCCTCAGGGCCTGGCTGTCCTGGGCATCCTAATTGAGGTGGGTGAGACTAAGAATATAGCTTATGAACACATTCTGAGTCACTTGCATGAAGTCAGGCATAAAGATCAGAAGACCTCAGTGCCTCCCTTCAACCTAAGAGAGCTGCTCCCCAAACAGCTGGGGCAGTACTTCCGCTACAATGGCTCGCTCACAACTCCCCCTTGCTACCAGAGTGTGCTCTGGACAGTTTTTTATAGAAGGTCCCAGATTTCAATGGAACAGCTGGAAAAGCTTCAGGGGACATTGTTCTCCACAGAAGAGGAGCCCTCTAAGCTTCTGGTACAGAACTACCGAGCCCTTCAGCCTCTCAATCAGCGCATGGTCTTTGCTTCTTTCATCCAAGGATCCTCGTATACCACAGGTGAAATGCTGAGTCTAGGTGTAGGAATCTTGGTTGGCTGTCTCTGCCTTCTCCTGGCTGTTTATTTCATTGCTAGAAAGATTCGGAAGAAGAGGCTGGAAAACCGAAAGAGTGTGGTCTTCACCTCAGCACAAGCCACGACTGAGGCATAAATTCCTTCTCAGATACCATGGATGTGGATGACTTCCCTTCATGCCTATCAGGAAGCCTCTAAAATGGGGTGTAGGATCTGGCCAGAAACACTGTAGGAGTAGTAAGCAGATGTCCTCCTTCCCCTGGACATCTCCTAGAGAGGAATGGACCCAGGCTGTCATTCCAGGAAGAACTGCAGAGCCTTCAGCCTCTCCAAACATGTAGGAGGAAATGAGGAAATCGCTGTGTTGTTAATGCAGAGAACAAACTCTGTTTAGTTGCAGGGGAAGTTTGGGATATACCCCAAAGTCCTCTACCCCCTCACTTTTATGGCCCTTTCCCTAGATATACTGCGGGATCTCTCCTTAGGATAAAGAGTTGCTGTTGAAGTTGTATATTTTTGATCAATATATTTGGAAATTAAAGTTTCTGACTTTAATTCTGGCCTATCCTTTGAGGCTCTTGAGGGTGGGCAAGTTCCTGAATCCCTCAGGTGGTAAAGATGGGCAAAGGATGGGGAAAAGAAGCATGGGTGATTAACTCCTTTTATCCCACCCCTGGAAGGAAAGATAAGCTTCTGGGAAGACACTTAACCCAAAGTTTCAGACATGTTAAACCACTAGCCCAGATTTCTGCCCTTGCACCAAGGCTATGCTTGGAAATCAGTGGTTGCCAGGTTAGGAAAGTGGCTGGATGAGAGATCTGAGGACAGAAATCTCAATTAACATGCTATCCCCTCCCTTAAAAGCCAAGTTCCCCCACAATTACAAATTCTTTTTTATTAGTCAAAATCACAATCACCTTGATTAAAAGGATGGGACACTCCACCCTCAGCAGAAAATGATACAGTTTATAGAAAACCTCCCCGCCCCTCCCACACCCCAATTAAAAACTACAAAAAAATCTCCCCTCCTTCCCTACGATGTCATGGTAGTCTGACTCCTCCAGTGGCACTGCAGCTCTGGAGTGGCCAGCTCACCACAGCACCCTCCACTTCACCTTGGGGAGAGGAGGGATGCTGGTGGTTAAGGAGGTTAAAACCATTAGTTCCAGTAATGCCAGTTCCCAAACATGCACTTCCTTCCTTTCCCCCAAGGTCTGGGACCAAGGAGAAAGGGACCGAAATGAGCCCAGCCATGAGGAGCAACTCGAGGAGAGAAAATATAGCCCAAGGAGGTTAGAAGAGTTCCAATATACCTCCTCCCTCCCCCCACCTCAAAAAA

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