Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HAUS4P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:170368921-170370255  UCSC
Coordinates (T2T) chr1:169724870-169726204  UCSC
Coordinates (hg19) chr1:170338062-170339396  UCSC
Strand -
Parental Sequence NM_001166269.2
Parental seq. overlap 1223 bp
Parental seq. overlap (%) 76.7%
Genomic Region Intergenic
Retrocopy Summary HAUS4P1, located on chr1:170368921-170370255, is a retrocopy of the parental gene HAUS4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HAUS4
Full Name HAUS augmin like complex subunit 4
Also known as C14orf94
Coordinate chr14:22946228-22957090
Strand -
Gene summary This gene encodes a subunit of the centrosome complex termed the human augmin complex. The encoded protein localizes to the spindle microtubules and may play a role in mitotic spindle assembly and maintenance of centrosome integrity during cell division. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HAUS4P1
Bonobo Pan paniscus HAUS4P1
Gorilla Gorilla gorilla HAUS4P1
Orangutan Pongo abelii HAUS4P1
Gibbon Nomascus leucogenys HAUS4P1
Green monkey Chlorocebus sabaeus HAUS4P2
Crab-eating macaque Macaca fascicularis HAUS4P1
Rhesus Macaca mulatta HAUS4P1
Baboon Papio anubis HAUS4P1
Golden snub-nosed monkey Rhinopithecus roxellana HAUS4P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HAUS4P1
AGACGCTGCTGTCCAGCCTGCCCCAGCCGAGGATCTTGGCACCCCCTTGAGAGCTTCACCTGCCCCAGTATTAGAATCCCAAGAAAATCAAAAGGTATTTGGGGATTTCTGCTCACCTGGAGAAGGGATGGAAATACTTCAACAAGGCATGGAAGGAAGTTCGACTGCATAAGACAACGTGGTTGAGGTCTGAGATTTTACATGGAGTTATTCAGGAGTTGCTTGTGGACTACTGTGTGAAGATACAGGACACAAATTTAACTTCTGAGGACAAAAATTTCATGAGACCCTTGAACAGCGGCTACTCATAACTGAACTGACATGGCTCTTAGGTCCTAGCCAGGAGAGGGAGATACCTTCACTGCTAGAGCTGGAGAAAGCGGACCTTCTGGAATCCATGCCACTCTCAGACGATTTTGTGTGGATGAGGGCTCTGCTACAGCAAGAAGTGGAGGAGTAGCTCAAGAAGAAATGTTTCACTCTGCTCTGGTACTATGATCCCAATTCAGATGCTGACAGTGAAACCGTAAAGGCAGCAAACGTGTTGAAACTTGCAGAGGTCCTAGTGGCTAGGAAGCAGCAGTGCCAGGATGCCAAGAGCCAGCAAAAGGAGCAGATGGTGCTGCTGGAGAAGAAGAGTGCCACCTACTTCCAGGTGCTTCTCTGCTGCCTCATTTTGCTGCAGAGGCTTCTTCAGGAACAACGGCTGAAGACTCACTCCGAGTTAGACCACATCAATGCCCAGTACCTGGAAGTCAAGTGTGGTGCTATGATACTTAAGCTGAGGATGGAAGAGTTAAATATTTTGTCCAACACACTGCTGAGAAAGTGGAAGTTCATTGTCCGATTAGGGACCGTTTGGAGGGAGCGATTCACCTACGGGAGCAGCACATGGAGAAGTCAAGACAGGTCCTGAACTCCTATGAAATACTTGGGGAGGAGTTTGACAGACTGGTGAAAAGAGTCCACCCTACTCAAGCAGGCAACTGAGAAGCGGTGGGCCCTCCAGGAGTTCAACAAGGCCTACTGTTGATCTCTGGCAGGGCCAGGAAGCATGGCTTCTGCACAGCTGCTGCCTCCTAATCTTCCTGCTAGTAGGACCACGTTCACCTGGGGCTGCCTTCGCTACAAGGGAGTGTGGGAACGTTTGCACTTGCTTGAAAGACTGCAGTCGTTTAGGCACCCTCCTGGTTTTTCTTTCTTGTTTATAATGACTGGGCCTCTTCTGGAAAATCTAGCAAGCAGATTTATATAATTTTTATGCATGGCTGTTTGTCTGTGTCAGCCCTGTATATTTGATTATCTCCTGAATAAAGTTATGATATTATATCTTAA
>NM_001166269.2
CTTTCAGCTTGGTCTTTCCGGGCCTCGCTTCCCCCAGCCCCTGCGCCCGGCCCGAACGAGAGGTTCCGGAGCCCCGGCGCGGGCGGGTTCTGGGGTGTAGACGCTGCTGGCCAGCCCGCCCCAGCCGAGGTTCTCGGCACCGCCTTGAGAGCTTCAGCTGCCCCAGGGTGTGCAGATTAGAATCCCAAGAAAATCAAATGGCATCCGGGGATTTCTGCTCACCTGGAGAAGGGATGGAAATACTTCAACAAGTGTGCAGCAAACAACTTCCTCCTTGTAACCTGAGTAAAGAGGACCTGTTACAGAACCCATACTTCAGCAAGCTTCTCCTGAATCTCTCACAGCATGTGGATGAGAGTGGCTTAAGCCTCACCCTAGCAAAGGAGCAGGCTCAGGCATGGAAGGAAGTTCGACTGCATAAGACAACATGGTTGAGGTCTGAGATTTTACACAGAGTCATTCAAGAGTTGCTTGTGGACTACTATGTGAAGATACAAGACACAAATGTAACTTCTGAGGACAAAAAGTTTCATGAGACCCTTGAACAGCGGCTGCTTGTAACTGAACTGATGCGGCTCTTAGGTCCTAGCCAGGAGAGGGAGATACCTCCACTGCTGGGGCTGGAGAAAGCGGACCTTCTGGAACTCATGCCACTCTCAGAGGATTTTGTGTGGATGAGGGCTCGGCTACAGCAAGAAGTAGAGGAGCAGCTCAAAAAGAAATGTTTCACTCTGCTCTGCTACTATGATCCCAATTCAGATGCTGACAGTGAAACCGTGAAGGCAGCAAAGGTGTGGAAACTCGCAGAGGTCCTGGTGGGTGAGCAGCAGCAGTGCCAGGATGCCAAGAGCCAGCAGAAGGAGCAGATGTTGCTGCTGGAGAAGAAGAGTGCTGCTTACTCCCAGGTGCTTCTCCGCTGCCTCACTTTGCTGCAGAGGCTTCTTCAAGAACACCGGCTGAAGACTCAATCCGAGCTAGACCGCATCAATGCCCAGTACCTGGAAGTCAAGTGCGGTGCTATGATCCTTAAGCTGAGGATGGAGGAGCTAAAGATTTTGTCCGACACTTACACTGTTGAGAAAGTGGAAGTTCATCGTCTGATTAGGGACCGTTTGGAGGGAGCCATTCACCTACAGGAGCAGGACATGGAGAACTCAAGACAGGTCCTGAACTCCTATGAGGTCCTTGGGGAGGAGTTTGACAGGCTGGTGAAAGAGTACACCGTACTCAAGCAGGCAACAGAGAACAAGCGGTGGGCCCTCCAGGAGTTCAGCAAGGTCTACCGTTGAGCTCTGGCAGGGCCAGGAGACATGGCTTCTGCATAGCTGCTGCCTCCTAATCTTCCTGCTAGTGGGACCACCTTCACCTGGGGCTGCCTTCAGTACAAGGGAGTGTGGAAATGCTTACGCTTGAAACACTGCAGTCATTTAGGCACTCTCCTGGTTTCTCTTTATTTTTTATGACTGGGCCTCTTCTGGAAAATCTAGCAAGGAGATTTATATAATTTTTATGCATAGCTGTGTGTCAGTGTCAGCCCTGTATTGTATTTGATTATCTCCTGAATAAAGTTATGATATTATATCTTA

Publications

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