Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZNF75DP1
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:78383950-78386910  UCSC
Coordinates (T2T) chr11:78317237-78320197  UCSC
Coordinates (hg19) chr11:78094996-78097956  UCSC
Strand +
Parental Sequence NM_007131.5
Parental seq. overlap 2587 bp
Parental seq. overlap (%) 45.7%
Genomic Region Intragenic (GAB2)
Retrocopy Summary ZNF75DP1, located on chr11:78383950-78386910, is a retrocopy of the parental gene ZNF75D. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZNF75D
Full Name zinc finger protein 75D
Also known as D8C6|ZKSCAN24|ZNF75|ZNF82|ZSCAN28
Coordinate chrX:135285787-135344629
Strand -
Gene summary This gene encodes a protein that likely functions as a transcription factor. The protein, which belongs to the ZNF75 family, includes an N-terminal SCAN domain, a KRAB box, and five C2H2-type zinc finger motifs. Another functional gene belonging to this family is located on chromosome 16, while pseudogenes have been identified on chromosomes 11 and 12. Alternative splicing results in multiple transcripts variants. [provided by RefSeq, Jun 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZNF75DP1
Bonobo Pan paniscus ZNF75DP1
Gorilla Gorilla gorilla ZNF75AP1
Orangutan Pongo abelii ZNF75DP1
Gibbon Nomascus leucogenys ZNF75DP2
Green monkey Chlorocebus sabaeus ZNF75DP1
Crab-eating macaque Macaca fascicularis ZNF75DP2
Baboon Papio anubis ZNF75DP2
Golden snub-nosed monkey Rhinopithecus roxellana ZNF75DP2
Marmoset Callithrix jacchus ZNF75DP2
Rhesus Macaca mulatta Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZNF75DP1
CAGTGGTGCAGGAGCAGAGAGCTTCACTGCCCAGAGCAGCAGCGTGGCGACAGAGGCATAGTTGAGCAAAGAAAGAGGAAAGGGGCCTCCAGGGAAGCCAGAGCTGACTGAAGTGTTCTTGGGAAGATCTATTCATTGATTTTGTACCAAACCTGCACTCTCATTTTGTACCAAAATGTACCAAACCTGATGCACCTCAAAGGTGGCACCAGATGGGTGTGAATGTCACACACAGGAGTAAAACTCTTCCTAGAGCAAATGATAATGAGAGAGCTGAAGGCAGATGCATGCTTGAACTCTCATATGGGAGCTATGTGGGAGACCAACAGGTCTGTGAAAGAGAACTCCAGTCAGAGTAAGAAATACAGCACACAAATCGAGTGTCTCAGTCCTGGGAGTGCTTGCAGGCACTTCCGGAGCTTCCATTATCATGAAGCAACTGAACCGCTTGAGGCTATCAACCAACTTCAGAAATTGTGCCATCAGTGGCTGAGGCCAGAGATCCACTCAAAAAAGCACATTTTGGAAATGCTGGTACTAGAGCACTTCCTGACCATCCTGCCAAAGGGGACCCAGAACTGGGTGCAGAAGCATCATCCACAGCTTGCCAAACAGGCCCTGGTCCTGGTGGAACGCTTGCAGAGAGAACCTGGTGGAACAAAGAATGAGGTCACAGCCCATGAGCTGGGAGAGGAGGCAGTGCTCTTGAGAGGAACAACAGTGGCCCCAGGCTTCAAGTGGAAGCCAGCAGAGCTCGAACCAATGGGTCTGTTCTAGAAAGAATACTGGAACACATACAGGGTACTACAAGAACAGCTGGGCTGGAATACTCAGAAAGAAACCCAGCCTGTATATGAAAGAGCTGTGCATGTTCAACAGATTTTAGCCCTTTCTGAGCACAAAAGCACCAAAGACTGGAAGATGGCACCTAAGCTCATCTGGCCTGAGTCCCAGAGTTTATTGACATTTGAAGACATGGCTGTGTACTTCTCTGAGGAAGAATGGCAATTATTAGGTCCTCTTGAGAAGACTCTCTACAATGATGTAATGCAGGATATCTATGAGACTGCCATCTCTCTAGGGTTAAAGCTAAAAAATGACAATGGAAATGACTATCCTATAATATCGGTTTCTGCACCTGAAATACAAACAGCAGGATACAAAGTATCAAAAAAGACCAGAATGAAAATTGCCCAGAAAACAAAGGACAGGGAAAATCATGGTGATACACACAGGGTATAGAAATGGCATCAAGCTTTTCCAAGGAAGAAAAGAAACTTACAACTTGTAAACAAGAGCTTCCAAAACTTATGGATCTTCACGGGAAAGGCCACACAGGAGAGAAACCTTTTAAATGTCAGGACTGTGGGAAAATCTTCAGAGTTAGCTCAGATCTTATTAAGCACCAGAGAATTCACACTGAAGAGAAACTCTATAAATGTCAACAATGTGACAGGAGGTTTAGATGGAGTTCAGGTCTTAATAAGCACTTCATGACACATCAAGGAATAAACCCATATAGATGCTCATGGTATGGGAAAAGCATTAGTTATGACACAAATCTACAAACACACCAAAGAATTCACACAGGAGAGAAGCCCTTTAAATGTCATGAATGTGGGAAAATATTCATTCACAAATCCAACCTTATTAAATACCAGAGAACTCACACAGGTGAGCAGCCTTATACTTGTAGCATATGCAGGAGAAACTTTAGTAGGCAGTTGAGCCTTCTTAGACACCAGAAACTCCACAGAAGATGGGAAGCATGTCCAATGTCTCCAAACTGAGGAAAGTTACCATGTAGAGATTGATTTTAGATGTGATGAAAGAATACAAAATTATGAGGCACCCAATGATAGGAATCTGTCATCAACAGAACATTTGGGAGGGGTACATATTATGCTTCACAAAAGTTATCTAACtTTATTAATAAAAAAATGAAAGTGTAGCTATGAGATATCTTTACCTGTCTATCTATACGTATGTATCTGGTTATTCAAAGCTTCCCCATCCCCAGTCAGTGCCTGAGATATATGATGGTCAAGACTCTTAGACTCATTCTTTATTCTTTGTCAGGAGAGATGGAAGGTAAGAGTACCTGGGCCCTCTCAAGGGAGTTCAGAGAGAATTACTAAGTTAGGGACAGTTTCAATAGCTATCATTCTATCTATGTGAACAATCAAACCCAGGACTCAGGGAACTTTATAACAGAAAGAGGATTCAGTGTTTGCCCTGGGAGAAGTGCCCCATTCTAGTTGCTTCTTTCCTGAGTACCCACTACCACAATGTCTTCTGTCAAGGAATTACAAGTAGCAAGGGAAGGTCTGGCTACAAGGACAGACCTAGGGACCCTGCAAGCACTTGATATCTCTTCTCTTGCTGACTCTGTCAACACAGACAACACAAAATGGAATGATGAAGGAGGCAGTCTTGGCCCTCATCCAGGTATCTGTTTCTTTGTAGAAAGTACACATAAGTAATGAAGGTCTTTTTCTGACTTTCATTATGTGCACTGGATGGAGGCTTTCAAACTGGTGCTACACTGCTGCAGGGCCTAAAGGGAGGCCTGTCCTTATGGCTGATCAGCTACAACCCTATATGCCTGAATACTCTGCAAGAAGGCCTGGAGGTTTTCCAAAACTGATTTATTGAGAATGGCAAGGAGGGCCCTGTGACCTCTTAGCCTTGGTGCACAGCTAATACCAGGAGGGAACATCCTGAAGTGTCAGAGCAAAGTAAGGCATGTGGCTTAGAGTAATGACCGCAGTCAGGGCCAGGCAAGATGTAAATTGTTTACTCATGTTATTGGTTTTCCTGTCTTCCCTACTGGCCAAAGTGACTATCTCTTACGAAGAGACAATGTGATGTCAAGGAAGTTGGAAGGCACGGATTTACATCT
>NM_007131.5
AGACCTGATCCAATGGCCGCTTGATACAATGGTGTCGTTCGGGAAACGCAGCCCTAACGTTGGTCCTAAGCTGACAAATTGGTCTGTGGACGCCAAACTTCCGTGCTAGGACTTTCTGCGTGTGGACCGGGGGCCTAGTCCTGCGTGGGTCCAACACAGACAGGAGAAAGCTGCCTGCTTTTGTGCCTCCCGGAGGTCCTGGTAGAAGCGAAACGGGGACAGGAGCTGCAGCGTCCCAAGCCCAGTGAGGCGAAGCTACTGGAGACAGCTCTGCCGGGTCCAAAGTTGGGCTCACCGGCTGGAACTTGAAACCGGAGCACGCCGGACTCCTGCTGAAGCCATCATCTCTCTCTCCTGGCCCCGGGCGCCTTGGCCGGCGGGCACAACTGGTTTCGGGGCCAAGGTGGTCTGGAAGCCTGACTGTGGCGTCTGGCCTGGGCTCCCGCGAGCGGAAAAGGTTCCCCTCCTGTGAGAGGGAAACTATGGAAGTTCCTACGCCCGGAGCCAGAACTCCTGCTGCTCCCGCCCGACCCAAGGTCTAGCTTGGCGGCCTCCCACCTGTGCTTCTGAGGGTTCTGCTTCCAAGAGGCTGCTGGTGCCCGGGACACCAGCAGTTTCGCCATGGGTGTTTCGCCATGGGAGTTTCGCCATGGGTGACTTTGGCCTGAGATGCGCTCCATGGAGCAGATTCTGGAGTTGCTGGTGTTGGAGGAGTTCCTGACTATCCTGTCCCAGGACATCCACAGCAGGGTGCAGAAGCTGCAACGGGCGAGCTGTGAAGAAGCTGTAACTCTTTTAAAGTATATGTATGACTTTTAAAAGAGAGAGCTTGTGAAACTGAGGGAATAGGTGAGTGAGAGAGAGGTTTTATCTGCCATcttcctcaaggaggcccagcctcccctttattcatagggttctgggtctgGTGGGTCCAGAGGACTGAGACATCTCGCTGTCTTAATTCCCCATTCAGATTTTCTTGATTGCCCTGAGTAGACCTTACACGGGCCAGTGATtttttgttgttgttgttgttgttgtCTTCTCTGGAACCTTCATCCTCCAGATTTCCCCCCAGTGCAGTGAAGAGTGTGCTATTGCTTTTGGTTTCCACGGGgaggcagtgtcgctgtcatagtgtccgctctggaggtagatcaaagggggctttcaactcctggctctgctccctactagctgtgcgactttgggcaagtgacttttgcttggctgggcttcactttctgcactggtcaaatgcagaaagggtaatagacccttctggggttgtttggaggattaaagggagagcagtatgtccgtaataatcgcactgctggcacacagctagtgcttgaaactgtgagctgctgttaGGTTAGGGGCAGCAGTCTGGTCTCCTCTGCAGAGATGGGTCTCAGTTAATTGTGAACTTAAACAGTTTGGCACTGAGGCTTTGGGGTCATTGCCCCAGGGCCACCCAAGTAAGCTTGTCTAATTGAGAGGAACAGGAGCAGCTGGAGAATGTGGGGGAGGAACCGAAGACCTATGGGGGACATGTGTGTACTGAAATGGGCTTTCTCCCCACACCCTCCACACAAGCACATACACACATTCACTCTGGGTCATGGCATCATAAAAACCTTGAGTTTAAACCATCCCTTTCTCTTGTTGGGTCCAAATGGACAGACTCTGGTTTTCTATTGAAGATTTACACGCAGATTCCTGTCATAATTTTTCTTTTCTATCGAGCCCTGTCATGATGATAAGTGATAGCAGGTTGGTTCCTAGATCATACACCATGGACCTAGCACAGAAGTGTTTTCAGAAGAGCCTTTTCCTTACAAAACAGCATGAAAGTCATTGAGCCAATGGATACTGAGATTTCAAACTGGAGCCAATGGATACTTAGAGGAGCCCTGaagtgtagagtagttgctacttcttgttcactaggtctaattagcatgtcatcagtgtaacagactagtgtgttgtcttgtgaaagagaaaggtgataagatccctgtgaactaaactatgatgtagggcttgaaaattgatatacaatacgcctgaggtaggatggcgaaggtgtattcctggtcttaccagctgaaagtaaattgcttctggtggtctttactaacagttattgagaaaaaaagcattttcaaggtcaagaggtacatactaggttccaggggatatgttaatttgctcaagaaatgaaaccacatctggaacagcagctgcaattggagtcatcacctggcttagtttacaatgacccactaccatcttccaagatccatctgccttctgcataggccaaacagGTCCACAGAACTCGACCCTGGAAGAGAGAGTCGGGGTCAGGTCTTCGGGAGGTGGAGGGATCGAATGAGGGAACTGATATTCCAAGACTCCCCACATCTTGGAGCTTCACTCGCCAGGCATCCCGCGCTTTCCTGACGTCGCTTCCCCTAGTGGTGCAGCAGCGGAGAGCTTTGCTACCCAGAGCAGCAGGGAGGCGTGGCCACAGAGGCAGAGGCGTAGTCGAGCCGAGGAAGAGGAAAGTGGCCTCCGGGGAAGCCAGAGCTGACTGAAGTGCTCTTGGGAAGAACAATTCATTGATTTGGTACCAACCTGATGCACCCTGATTTGTCAAAGGTGGTACCAGGTGGGTGTCAGTGTCACATACAAGAGTAAAACTGTTCCTAGAGCAAATGGCGATGAGAGAGCTGAACGCGGATTCATGCTCAAGCCCCCAGATGGGGGCTATGTGGGAGACTAGTGGGTCTGTGAAAGAGAACTCCAGTCAGAGTAAGAAATACAGCACAAAAATAGAGAATCTTGGTCCTGAGAGCGCTTGCAGGCACTTCTGGAGCTTCCGTTATCATGAAGCAACCGGACCGCTTGAGACTATCAGCCAACTTCAGAAATTGTGCCATCAGTGGCTGAGGCCAGAGATCCACTCAAAAGAGCAGATCTTGGAAATGCTGGTGTTAGAGCAGTTCCTGAGCATTCTGCCCAAGGAGACCCAGAACTGGGTGCAGAAGCATCATCCACAGAATGTCAAACAGGCTCTGGTCCTGGTGGAATTCTTGCAGAGGGAGCCTGATGGAACAAAGAATGAGGTCACAGCCCATGAGCTGGGAAAGGAGGCAGTGCTCTTGGGAGGAACAGCAGTGGCCCCAGGCTTCAAGTGGAAGCCAGCAGAGCCCCAACCAATGGGTGTGTTCCAGAAAGAATATTGGAATACATACCGGGTACTACAAGAACAGCTGGGCTGGAACACTCACAAAGAAACCCAGCCTGTATATGAAAGAGCTGTGCATGATCAACAGATGTTAGCCCTTTCTGAGCAGAAAAGAATCAAACACTGGAAGATGGCATCTAAACTCATCCTGCCTGAGTCCCTGAGTTTGTTGACATTTGAAGATGTGGCTGTGTATTTTTCTGAGGAAGAGTGGCAATTATTGAATCCTCTTGAGAAGACTCTCTACAATGATGTAATGCAGGATATCTATGAGACTGTCATCTCTCTAGGGTTAAAGCTAAAAAATGACACTGGAAATGATCATCCTATATCTGTTTCTACATCAGAAATACAAACATCAGGATGCGAAGTATCAAAAAAGACCAGAATGAAAATTGCCCAGAAAACAATGGGCAGGGAAAATCCTGGTGATACACACAGTGTACAGAAATGGCATCGAGCTTTTCCAAGGAAGAAAAGAAAGAAACCTGCAACTTGTAAACAAGAGCTTCCAAAACTTATGGATCTTCATGGGAAAGGCCCCACAGGGGAGAAACCTTTTAAGTGTCAGGAATGTGGGAAAAGCTTCAGAGTTAGCTCTGATCTTATTAAACACCACAGAATTCACACTGGAGAGAAACCCTATAAATGTCAACAATGTGACAGGAGGTTTAGATGGAGTTCAGATCTTAATAAGCACTTCATGACCCATCAAGGAATAAAACCATATAGATGCTCATGGTGTGGGAAAAGCTTTAGTCATAACACAAATCTACACACACACCAAAGAATTCACACAGGAGAGAAGCCCTTTAAATGTGATGAATGTGGAAAAAGATTCATTCAGAACTCCCACCTTATTAAACACCAGAGAACTCACACAGGTGAGCAGCCTTATACGTGTAGCTTATGCAAGAGAAACTTTAGTAGGCGATCGAGCCTTCTTAGACACCAGAAACTCCACAGAAGAAGGGAAGCATGTCTAGTGTCTCCAAACTGAGGAAAGTTACCATGTAGAGCTTGACTTTAGAAGTGGTGAAAGAATACAAAATTATGAGGCACCCAATGATAGGAATCTGTGATTAATAAAACATTTGGGAAGGGTACATGTTACACTTCACAAAAAGGAATCTAAGCTgtctgttttattcagcattgcatcttctgtgcctagcacaagagttgatacataaggagtactttataaatAAAAAAATGAAAGTGTAGTGATGAGATTCCTTTAGCTATCTATCTATATGTATATATCTGGTTATTCAAAGCTTCCCCACCCCCAGTCATCTAAATTTTTCAGGTATCAAGTGCTCAACAGACATATGATAGTCAAGGCTCTTAGTCTCATTTTTTACTCTTTGTCAAGAGAAATGGAAAATAAGAGTACTTGGGCCCTCTTAAGGGAGCTCAGAGAGAATTACTAAATTAGGGACAGTTTCAATAGTTATCATTCTGTCTACATGAACAATCAAGACCAGGACTCAGGGAACTTTACTCTGTAACAGAAAGAGAGGATTCAGTGTTTGCCCTGGGAGAATTGTCCCATTCTTGTTGCTTCTCTCCTGAGTACCCACTACCACAATGTCTTCTGTCAAGGAATTACAAGTAGCAAGGGAAGGTCTGAATGTAAGGACAGGCCTAGGGACCTTGCAAGCACTTGATATCTCTCCTCTTGCTGACTTTGTCAACATAGACATATAGTGAAATGATGAGGGAGGCAGTCTTGGCCCTCATCCAGGTATCTGGTTTTTTTTTGTAGAAAGCACAGATAAGTGGTAAATGGTCTTTTTCTGACTTTCATTATGTGGACTGGATGGAGGCTTTCAAACTGGTGCCATACTGCTGCAGGACCTAAAGGGAGCCCCATCTTTATGGCTGATCAACTACAACCCTATATGCCTGAATACTCTGCAAGAAGGCCTGGAGATTTTGCAAAACTGATTTATTGAGAATGGCAAGGAGAGCCTTGTGAACTTTTAGCTTTGGTGCACAGCTGATACCAGGAGGGAACATCCTGAAGTGTCAGAGAAAAGTAAGGCATATGGCTCACAGTGATGATGCCAGTCAGAGCCAGGCCAGATGGAAATTGTTTTCTGATGTTACTGGTTTTCTTTTCCCTATTAGCCAAAGTGACTATCTCTTAAGAGAAGATAATGTGACGTCAAGGGAAGTTGGAAGGCATGGATTTATATCTATGTCAGATCCTGGTTTATAATGTTGGCCAAGGCTTATTTATATATGTTTATTTAGTATTCCATAAAATTGTACTTCGTAATGAAAATGACACATTTTATCTTAAATTTAGACAATAAACAAAACTTTGTTACCAAATCA

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