Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DHX9P2
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:85451987-85453750  UCSC
Coordinates (T2T) chr11:85388639-85390402  UCSC
Coordinates (hg19) chr11:85163031-85164794  UCSC
Strand -
Parental Sequence NM_001357.5
Parental seq. overlap 1442 bp
Parental seq. overlap (%) 31.4%
Genomic Region Intragenic (DLG2)
Intragenic (MPP2)
Retrocopy Summary DHX9P2, located on chr11:85451987-85453750, is a retrocopy of the parental gene DHX9. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DHX9
Full Name DExH-box helicase 9
Also known as DDX9|LKP|NDH2|NDHII|RHA
Coordinate chr1:182839347-182887982
Strand +
Gene summary This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.[provided by RefSeq, Feb 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DHX9P1
Bonobo Pan paniscus DHX9P1
Gorilla Gorilla gorilla DHX9P1
Orangutan Pongo abelii DHX9P1
Gibbon Nomascus leucogenys DHX9P2
Green monkey Chlorocebus sabaeus DHX9P1
Crab-eating macaque Macaca fascicularis DHX9P1
Rhesus Macaca mulatta DHX9P1
Baboon Papio anubis DHX9P1
Golden snub-nosed monkey Rhinopithecus roxellana DHX9P1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DHX9P2
AAACTCCTGTGTCTGGGAGAAATTGGCTAATTTCTGGCCAAGGCAATCCAAGGACCTCCACCTTTGGATCCTGTGATTTAGGCAGAGCACACTCTTGGAGAGCTTGATGCATTATATGGCAATGATAAGTTTAATTCTCTAGGATGGGTCCTGACTAAACTCTCCATTGAGCCTCATCTTGGCAAAACGATGATAATGGGGTGTATTTTCTATGAGAGAGATCCTGTCTATACCATCTCTGCTGCTACCTGTTTTCATTGATGAAGGAAAGTGGGATATATCCACCGAAATTTTGCTGGAAACCCATTTTCTGATTATGTGTCCCTTTTATCAGTATTCCAATCCTGGAATGATTCTAGAACGGGTAGAGAAGAAACTCAGATTCAATTTTGTGAGCACAAAAGACTCAATAGGGCTACACTAAGAATGACTTATGAAGCCAAAGTTTAGCTCAAAGAGATTCATATTAATTCTGGATTTCCAGAAGATTATTGACACAAGTGTTTACTAACACTGGACCAGATAATAATTTGGATGCTGTTATCTCCCTCTTGGCCTTTGGTGTGTACCCAAATGATGCTATCAGAAGGAAAAGAGAAATATTCTCACCATGAAGGGCATAATGCACTTATCCACAAATTGTCTGTTAATTGTTTTTTTAGTAGCAAGACAAAAAGTGCTCCTCTCTTTTCTTTGTGTTTGGTGAAAAGCCGGGGGTGACTAAGGCCGTGCCTTTAGCAGAGATGGCTCGGGTTCAAATACTGTCTTTGATCAGGTGTACTTGAATCTGAGCCATCTCTGCTAAAGGCATGACCTTAGTCACCTCCCTGAAGTTGCTTCTCTTTGCCTTCAAGAAAGTATAATGTGATAGGCAGATTGTTCTTGTAGATGACTGAATTAAACTGCAAATATCCCATGAAGCTGCTGCCTGCATTACTGCTTTCCAGGAAATCTTGGAGTTGAAGATTCAACAACCTCTGGTTGTTGAAGTAACAAACAACCTGATATCTTCAGCCAGTTGGACCCTTTTAATTAATATATGCTGAACATTATCCACCAAATCTCTAGGCCCTTAGCTCCTGTTATCAATCTTGTGGTTGGCAATACACAGTATGGAGATGGTCCACATCCTCCCAAGATGGCCTGATATGACAATGGAAGTAGATATAGGAGGGTACATTCTAGTTATGGTGTTGGAGGCTATGGCAGTGGCTACAGTGATGGAGGCTATAGTAGTGGAGGCTATGGTGGCACTACTCCACCCTGTCAGGAAGGATATGGTGGAGATGGTGGTGGAGACTATAGAGGACATAACTGAGGTGGCTATAGTGGTAGCTCTGGTGGAGACTACAGAAGGTCTAGTGGAGGTTTCAGAGGATCTGGGAGATGCCAGTGAGGATATGGAAGGGAGAGCTATGGAAATGGCTGCTTTGGACAAGGAAAAGGAAGTGGTGGCCATTAAGGCTTGGTTATGTCAGTGCCTGTGCATAGACAGTTAAAAAAAAAAACAACTACCTGTTTTTCCCAAGATGTTTGTTTTTCACCAAAAACTAAACCCATTTTCCACACATTCTATGGTTCATTGTAGTTTAAGGAAACCAAGCATATAGATGCATTAGTGATTTTATTTATATTATGTAAAATATAATCTATTATAAAAATACCACAGTTTGTATTTTTTCTTTAAAGAGTAAAGATTTGCTTTTAAAGTTAATTTGATATTTTCTTGGCTTTCATTTAATACATTGGAAAATACAGTATTAT
>NM_001357.5
GCCATTTCGCCGATTCCTCCATGCGAGTTGCTGTGCGTTTCTCTGTTGTCTCGGTAGAAGGCCAGAGTCACACACGGTCCTAAGAGCTGGGCACCAGGAAGCGAAGGCTGATCTGAAGAAGACACTTGAATCATGGGTGACGTTAAAAATTTTCTGTATGCCTGGTGTGGCAAAAGGAAGATGACCCCATCCTATGAAATTAGAGCAGTGGGGAACAAAAACAGGCAGAAATTCATGTGTGAGGTTCAGGTGGAAGGTTATAATTACACTGGCATGGGAAATTCCACCAATAAAAAAGATGCACAAAGCAATGCTGCCAGAGACTTTGTTAACTATTTGGTTCGAATAAATGAAATAAAGAGTGAAGAAGTTCCAGCTTTTGGGGTAGCATCTCCGCCCCCACTTACTGATACTCCTGACACTACAGCAAATGCTGAAGGAGATTTACCAACAACCATGGGAGGACCTCTTCCTCCACATCTGGCTCTCAAAGCAGAAAATAATTCTGAGGTAGGGGCCTCTGGCTATGGTGTTCCTGGGCCCACCTGGGACCGAGGAGCCAACTTGAAGGATTACTACTCAAGAAAGGAAGAACAAGAAGTGCAAGCGACTCTAGAATCAGAAGAAGTGGATTTAAATGCTGGGCTTCATGGAAACTGGACCTTGGAAAATGCTAAAGCTCGTCTAAACCAATATTTTCAGAAAGAAAAGATCCAAGGAGAATATAAGTACACCCAAGTGGGTCCTGATCACAACAGGAGCTTTATTGCAGAAATGACCATTTATATCAAGCAGCTGGGCAGAAGGATTTTTGCACGAGAACATGGATCAAATAAGAAATTGGCAGCACAGTCCTGTGCCCTGTCACTTGTCAGACAACTGTACCATCTTGGAGTGGTTGAAGCTTACTCCGGACTTACAAAGAAGAAGGAAGGAGAGACAGTGGAGCCTTACAAAGTAAACCTCTCTCAAGATTTAGAGCATCAGCTGCAAAACATCATTCAAGAGCTAAATCTTGAGATTTTGCCCCCGCCTGAAGATCCTTCTGTGCCAGTTGCACTCAACATTGGCAAATTGGCTCAGTTCGAACCATCTCAGCGACAAAACCAAGTGGGTGTGGTTCCTTGGTCACCTCCACAATCCAACTGGAATCCTTGGACTAGTAGCAACATTGATGAGGGGCCTCTGGCTTTTGCTACTCCAGAGCAAATAAGCATGGACCTCAAGAATGAATTGATGTACCAGTTGGAACAGGATCATGATTTGCAAGCAATCTTGCAGGAGAGAGAGTTACTGCCTGTGAAGAAATTTGAAAGTGAGATTCTGGAAGCAATCAGCCAAAATTCAGTTGTCATTATTAGAGGGGCTACTGGATGTGGGAAAACCACACAGGTTCCCCAGTTCATTCTAGATGACTTTATCCAGAATGACCGAGCAGCAGAGTGTAACATCGTAGTAACTCAGCCCAGAAGAATCAGTGCGGTTTCTGTGGCAGAGCGAGTTGCATTTGAAAGAGGAGAAGAGCCTGGAAAAAGCTGTGGCTACAGCGTTCGATTTGAGTCTATACTTCCTCGTCCTCATGCCAGTATAATGTTTTGTACTGTAGGTGTGCTCCTGAGAAAATTAGAAGCAGGCATTCGAGGAATCAGTCATGTAATTGTAGATGAAATACATGAAAGAGATATTAATACTGACTTCCTTTTGGTAGTACTGCGTGATGTTGTTCAGGCTTATCCTGAAGTTCGCATTGTTCTTATGTCTGCTACTATTGATACCAGCATGTTTTGTGAATATTTCTTCAATTGCCCCATCATTGAAGTTTATGGGAGGACTTACCCAGTTCAAGAATATTTTCTGGAAGACTGCATTCAGATGACCCACTTTGTTCCTCCACCAAAAGACAAAAAGAAGAAGgataaggatgatgatggtggtgaggatgatgatGCAAATTGCAACTTGATCTGTGGTGATGAATATGGTCCAGAAACAAGGTTGAGCATGTCTCAATTGAACGAAAAGGAAACTCCTTTTGAACTCATCGAGGCTCTACTTAAGTACATTGAAACCCTTAATGTTCCTGGAGCTGTGTTGGTTTTTTTGCCTGGCTGGAATCTGATTTATACTATGCAGAAGCATTTGGAAATGAATCCACATTTTGGAAGCCATCGGTATCAGATTCTACCCCTGCATTCTCAGATTCCTCGAGAGGAACAGCGCAAAGTGTTTGATCCAGTACCAGTTGGAGTAACCAAGGTTATTTTGTCCACAAATATTGCTGAAACAAGCATTACCATAAACGATGTTGTTTATGTCATTGACTCCTGCAAGCAGAAAGTGAAACTCTTCACTGCTCACAACAATATGACCAACTATGCTACCGTATGGGCATCAAAAACAAACCTTGAGCAACGGAAAGGGCGAGCTGGCCGAGTACGGCCTGGATTCTGCTTTCACCTGTGCAGCCGAGCTCGTTTTGAGAGACTTGAAACCCACATGACACCAGAGATGTTCCGAACACCATTGCATGAAATTGCTCTTAGCATAAAACTTCTGCGTCTAGGAGGAATTGGCCAATTTCTGGCCAAAGCAATTGAACCTCCCCCTTTGGATGCTGTGATTGAAGCAGAACACACTCTTAGAGAGCTTGATGCATTAGATGCCAATGATGAGTTGACTCCTTTGGGACGAATCCTGGCTAAACTCCCCATTGAGCCTCGTTTTGGCAAAATGATGATAATGGGGTGTATTTTCTACGTGGGAGATGCTATCTGTACCATTGCTGCTGCTACCTGCTTTCCAGAGCCTTTCATCAATGAAGGAAAGCGGCTGGGCTATATCCATCGAAATTTTGCTGGAAACAGATTTTCTGATCACGTAGCCCTTTTATCAGTATTCCAAGCCTGGGATGATGCTAGAATGGGTGGAGAAGAAGCAGAGATACGTTTTTGTGAGCACAAAAGACTTAATATGGCTACACTAAGAATGACTTGGGAAGCCAAAGTTCAGCTCAAAGAGATTTTGATTAATTCTGGGTTTCCAGAAGATTGTTTGTTGACACAAGTGTTTACTAACACTGGACCAGATAATAATTTGGATGTTGTTATCTCCCTCCTGGCCTTTGGTGTGTACCCCAATGTATGCTATCATAAGGAAAAGAGGAAGATTCTCACCACTGAAGGGCGTAATGCACTTATCCACAAATCATCTGTTAATTGTCCTTTTAGTAGCCAAGACATGAAGTACCCATCTCCCTTCTTTGTATTTGGTGAAAAGATTCGAACTCGAGCCATCTCTGCTAAAGGCATGACTTTAGTCACCCCCCTGCAGTTGCTTCTCTTTGCCTCCAAGAAAGTCCAATCTGATGGGCAGATTGTGCTTGTAGATGACTGGATTAAACTGCAAATATCTCATGAAGCTGCTGCCTGTATCACTGGTCTCCGGGCAGCCATGGAGGCTTTGGTTGTTGAAGTAACCAAACAACCTGCTATCATCAGCCAGTTGGACCCCGTAAATGAACGTATGCTGAACATGATCCGTCAGATCTCTAGACCCTCAGCTGCTGGTATCAACCTTATGATTGGCAGTACACGGTATGGAGATGGTCCACGTCCTCCCAAGATGGCCCGATACGACAATGGAAGCGGATATAGAAGGGGAGGTTCTAGTTACAGTGGTGGAGGCTATGGCGGTGGCTATAGCAGTGGAGGCTATGGTAGCGGAGGCTATGGTGGCAGCGCCAACTCCTTTCGGGCAGGATATGGTGCAGGTGTTGGTGGAGGCTATAGAGGAGTTTCCCGAGGTGGCTTTAGAGGCAACTCTGGAGGAGACTACAGAGGGCCTAGTGGAGGCTACAGAGGATCTGGGGGATTCCAGCGAGGAGGTGGTAGGGGGGCCTATGGAACTGGCTACTTTGGACAGGGAAGAGGAGGTGGCGGCTATTAAAACTTGGTTATGTCAGTTCCTGTGTGTAGACAGTAAGGAAAAAAAGGCATGCTATGTGTTACGTGTTTTTTCCAGTATGTTTATTTGCCACCAAAAAGTAAATGCATTTTCACCCATTCTGTGGTTCATTGTAGTTTAAGGAAACCAAGCATATAGATGCATTAGTGATTTTGTTTATATTATGTAAAATATAACGATCTCTTAAAAATACCACAGTTTGTATTTTTTCTTTAAGGAGTAAAGATTTGCCTTTAAATAACTTGGTATTTTCCTGGCTTTCGTTTAATACAATAGAAAATAAAGTATTACACCGAATACTTGCCGTGTAGTTTGTTTGTTGACCTCGTATGTTAGAAAATTTTACAATGCCAGCTACATCTGTTGATTTTAAATGTCAGAGAAGTTGTACCCTGTTTCAAAAGTATACTAAGTGATACTACTTGTAATAGAATAAATCATCTTGGAATTGAATTGTTACCTTTTGAAGTAAATACTGGCAAGTGCACAAGCCACATAAACCTGAATAAAACTTTTGACCTAGGGTTGAA

Publications

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