Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MOB4P2
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:86819394-86821829  UCSC
Coordinates (T2T) chr11:86760142-86762577  UCSC
Coordinates (hg19) chr11:86530436-86532871  UCSC
Strand -
Parental Sequence NM_015387.5
Parental seq. overlap 1376 bp
Parental seq. overlap (%) 29.6%
Genomic Region Intergenic
Retrocopy Summary MOB4P2, located on chr11:86819394-86821829, is a retrocopy of the parental gene MOB4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MOB4
Full Name MOB family member 4, phocein
Also known as 2C4D|CGI-95|MOB1|MOB3|MOBKL3|PHOCN|PREI3
Coordinate chr2:197515554-197553699
Strand +
Gene summary This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HSPE1P19
Bonobo Pan paniscus LOC100982477P19
Gorilla Gorilla gorilla LOC101151505P18
Orangutan Pongo abelii MOB4P3
Gibbon Nomascus leucogenys LOC100605912P19
Green monkey Chlorocebus sabaeus LOC103217585P2
Crab-eating macaque Macaca fascicularis LOC102147033P21
Rhesus Macaca mulatta MOB4P4
Baboon Papio anubis LOC101019904P16
Golden snub-nosed monkey Rhinopithecus roxellana LOC104676747P19
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MOB4P2
ACAAGAAAATGTATTTGCATAGGCTCTTGCTTATCTTTGTTTTGCAAAATTGTCCTTCTTAGAAAACAGTCCTTAAAATTTTGACTCTTCCTGTTAGTAATTAATCTTTCATTTAACCAGCTAGGCAGCATTAAATAAAATTGAAGAAATACTGTAGTATTTATTTTACACCCCCTCCCCACAAAGTTTATGTTTGAATTACATGCACGTGGGAGATTATTTGCAATAATTCATAGGTTCCAAGGGTGTTGATGAATAGTTATACATTTTTTGGACTTTGTTATAATTCATTGTGGTAAGACTGATTCAAATGCAGATTTATCAATCTTATAATCTATTGAATGCCATTTTTGATAAAGCACTGGAGGTCTTATTGCCAAACTGATTGTAATGAGGCACTAAGGATGAAAACATTGTACATGTTGTGAAGAAAGTACTTAAATGCAACTTTTGAACAGATTTAACAAACATGAGGAACTTTTTATATTTAAAAGAGTTATTGTGAAATGAAGATGAAAATGTATTCATCTTAATTGTTTTTTCAAATTTAAGGGAATAATTTATACCATATTTTGAGACAAGAATGTACAGCAAAAGTGTGGGGAACAGTAGTATACTGAGAGAGTGTCTATACACAGTGTATGCCTTTCCAAACCTGCCAGTCTTTTTGGCTTTGAACAGTGCCCACCAGCCACAGTCATTACTGTTCCCCAACCCCCACTATCTCTTAAGAAGCCTTATGTTCACAGTGAAAGGAATGCTGACTTTGAAATTATGGGTTTATATTCATGTCACTATAAACCAATGGGAATGGTAATTTTTAAACAAACTTGCTAAATATTGAGAGACTAAACTAAGTTAATAAATTATATATAGCAGTGTAGGTGTTCTCTCTCAGACGCTGACACTATGGTCATGGCGGAGGGGGCAGCGTGCTGAGGCGGAACGGGCTGGGCACAGGATTTTTATAATTGGCCTGACGAACACTTTGAAGAAATAGACAGTACACTAGCTGTTCAACAGTATATTCAACAGAACATAAGAGCAGATTGCTCCAATATTGACAAAATTCTTGAACCAGCTGAAGGCCAAGATGAAAGTTATGGAAGTATGAACATTTAAGGGAATTCTGTCTTGAGCTAAACGGACTTGTTGTCAAACTTCAGAGTGAATGCCATCCAGATACTTGCACTCAAATGACAGCAACTGAACAATGGATTTTTCTTTGTGCAGCTCATAAAGCTCTGAAAGAGTGTCCTGCTATAGCCTATACCAGACACATACTTGATGGTGCTGCATGTCTTCTGAAGAGCAATCAATGTTTTCCCAGCAGGGTTAGCATAAAGAAGTAATCCGTAGCAAAACTAGGATCACTATACCTTAGGAGTTACAGAATATTTTCACATGTTTATTTTCATCATTGGTAGATATTTGATGAATATGAAAAGGAAACATTTTTGTGTCATCGGATTACTAAATTTGTGATGAATTAGATGAAATATAATTTGATGTCCAGGGATAACCTCATTGTACCAATTTTAGAAGAGGAAGTACAGGTTTCAGTTTCTGGGGAAAGTGAAGCATGAAGGGAATCATGGAAAAATGTACAGATCACATAATTAACATTAATTATGTACTGTATATATCATTTTAGACACATCAATCATGTATCCATATTATAGCTTCTTCATTTAGTATAAGTTTTTGTATGCTGGGTTTGCCTTTTAAAATGGGAAATACTTTTTAAGTTATTCATAAGCTGTATATTCACCAGTGTGGCACTCATGGTTTTAGAATAAGATTAGTACTATCTGTTTATAATGCCTGTTAATAAAAGAATTTACAGTTGGGTAAAATTGCTGCTAAACAATCATTGGATCACAATCCTCATCAAACATACCCATCTATAAAAAAAATTGAGCGAGAGCTTGAGGTTTCACACAAGCCCTTTACTAAAGAGGTAGAAATGTTTTTCTTTGTTTCACCCTGAGTTTAGATATCCTCAAAAATTCTATAGTACATAGATTTGTCTTACCTGTTAACTTTCCTCAAATGAGATAAAGTGTTTTAAAATTCTGTTTATAGTTTTTGATATGCATATATAATTATGTGTATATCTAAATACAAACGCAAATAAAGCGTTAGTAATACTTAAATAATTTTACTGTGCTACATAAAGTATAACATACTTGGAAAGGATTTACCTTTCTGCAACAATGGACTGGTACATACAGGATGATGATAATGATAAGGCACATAAATGATGTTCCCACTGGAAACCTGCCCTGTCCACTCCTCATTTCCCTTAACCTTATCCTCAAACTACTTTAGCTGAGAAGCTTTTCATGAGACTGTGAGTTAGTGGTGGc
>NM_015387.5
AGCCGCCTAGACGCTGGCACTATGGTCATGGCGGAGGGGACGGCAGTGCTGAGGCGGAACAGGCCGGGCACCAAGGCGCAGGATTTCTATAATTGGCCTGATGAATCCTTTGATGAAATGGACAGTACACTAGCTGTTCAACAGTATATTCAACAGAACATAAGAGCAGATTGCTCCAATATTGACAAAATTCTTGAACCACCTGAAGGCCAAGATGAAGGTGTGTGGAAGTATGAACATTTAAGGCAGTTCTGCCTTGAGCTAAATGGACTTGCTGTCAAACTTCAGAGTGAATGCCATCCAGATACTTGCACTCAAATGACAGCAACTGAACAATGGATTTTTCTTTGTGCAGCTCATAAAACTCCAAAAGAGTGTCCTGCTATAGACTATACTAGACACACACTTGATGGTGCTGCATGTCTTCTGAATAGCAATAAATATTTTCCCAGCAGGGTTAGCATAAAGGAATCATCTGTAGCGAAACTAGGATCAGTATGCCGTAGGATTTACAGAATATTTTCACATGCTTATTTTCATCATCGGCAGATATTTGATGAATATGAAAATGAAACATTTTTGTGTCATCGGTTTACTAAGTTTGTGATGAAATACAATTTGATGTCCAAGGATAACCTGATTGTACCAATTTTAGAAGAGGAAGTACAGAATTCAGTTTCTGGGGAAAGTGAAGCATGAAGGGAATCATAGGAAAAATGTACTGATCATATAATTAACATTATGTACTGTATATATCATTTTAGACACATCAATCATGTATCCATATTATAGCTTCTTTGTTTAGTATAGGTTTTTGTATGCTGGGTTTGCCTTTTAAAATGGGAAATACTTTTTAAGTTATTCATAAGCTGTATATTCACCAGTGTGGCACTCATGGTTTTTAAATAAGATTAGTATTATCTGTTTATAATGCCTGTTAATAAAAGAATTTACAGTTTGGTAAAATTGCTGCTAAACAATCATTGGATCACAATCCTCATCAGACAAACCCATCTGTAAAAAAAATGAGGGAGAGCTTGAGGTTTCACACAAGCCATTTACTAAAGAGGTAGAAATGTTTTCTATTGGTTTTACCTTGAGTTTAGATATCCTAAAAAATTCTGTAGTACGTAGTTTTGTCTTACCTGTTAACTTTCCCCAATTGAGATAAAAGTGTTTTAAAATTCTGTTTATAGTTTTTGATATGCATATATAATTATGTGTATATCTAAATACAAATGCAAATGAAGCATTAGTAATACTTAAATAATTTTACTGTGCTACATAAAGTATAACATACTTGGAAAGGATTTACCGTTCTGCAACAACGGACTGGTACATACAGGATGATCACAATGGTAAGGCACATAAATTATTTTCCCACTGGAAACCTGCCCTGTCCACCCCTTCTCATTTCCCTTAACCTTATCTTCAAACTACTTTAGCTGAGAAGCTTTTCACCAGACTGAGTTAGTGGTGGCTTATACCTATTTATATTTGTATTAATTGCTTACAGATTATACCTCATATTAGCAATTACATTACACTACAAGAAAATGTATTTGCATAGGCTCTTGCTTATCTTTGTTTTGCAAAATTGTTCTACTTAGAAAACAGTCCTTAAAATAGTTTGACTCTTCCTGTTAGTAATATATTAATCTTTCATTTAACCAGCTAGGCAGCATTAAATAGAATTGAAGAAATACCATAGTATTTATTTTACACCCCCTCTCCCACGAAGTTTATGTTTGGATTACATGCACGTGTGAGATTATTTGCAATAATTCATAGGTTCCAAGGGTGTTGATGAATAGTCATACATTTTTTTGGACTTTGTTATAATTCATTGTGGTAAGAATGATTGAAATGCAGATTTAACAATCTTATAATCTATTGAATGCCATTTTTGATAAAGCACTGGAGGTCTTATTGCCAAACTGATTGTAATGAGGCAGTAAGGGTGAAAACATTGTACATGTTGTGAAGAAAGTATTTAAATCCAACTTTTGAACAGATTTAACAAACATGAGGAACTTTTTTATTTAGAAGGATAATTTTGAAGATGAAAATGTATTCATCTTAATTGTTTTTTCAAATTTAAGGGAATAATTTATACCATCTTTTCAGACAAGAATGTACAGCAAAAATAAGGGGAACAGTAGTATACTGAGAGTGTGTGTATGTATAGTGTATGCCTTTCCAAGCTTGCCAGTCTTTTTGGCTTTGAACACTGCCCATCAGCTACAGTCATTACTGTTCCCCAACCCACAACTATCTTTTAAGAAGTCTTAGTTCACAGTGAAAGGAATGATGACTTTGAAATTATGGATTTATATTAATGGCACTATAAACCAATGGTAATGGTAATTTTTAAACTTGCTAAATATTGAGAAACTAAACTACTAAGTTAATAAATTATATATAGCAGTGTAGCTGTTCTCTCTAGATGGTGTCTCACAATGGATTTCTGTTGCTTGACTATTTTCTTAGTGAATATTTATACTAAGGTAGTGACTGAGATTTGGTGATCTGGCTGAGTATTTTGAAACACATTTTGAATAATATGGCTTAGTGTTAACGGGGACTTAAATATGATTTTTTTTTCTTACTCATTTCACCTTCCCTGTACTGTATGTTTGGAATTGATCATAAAACATCTCCAAAAGAAAATAATCAGTTTGTAGTCTTGCTTTTGTATTCATGTTGATAATCTTACTAATTGTGAAGTTGATTCACTACTATACTAGGTAAGACCTAAGTGAAACAGTTCCTGTTTTTCCTTAATACTGTTTTCAGAATTTTGAAAATGTACTTATATATACATAAATACTACTAAAAAATTAATGAGCCTGGCAAACCATTGATTTATAAAAGTAAGTGTTCTAAGAGGGGAACAAGACAGTTCTGTGTGATAAGGAAGTTAGGCTCCACTTTTTGTTTGAATTACCCTATGTATATCCGAAGGTAAACTTAGGCTTTTCTTTCCAAAAGATCGTATAGTCAATTCATTCTTTTTCTCCTATCACATCTGGGAAAGTAGCTAACTTTTAACTATTTATGTTCCCATAAGTAACCCTTCTTTTGTGTGTATACATTTCCTTTTCTCTGACTTGAGATGTCAAATTTGGATTTCTAGAACAGTTTCTCAGTTAAATTCTTGATGACTTAACAACTTTTACTATCAGAATACAATTAGAAATCCTTggtcaggcacaggggctcacgcctgtaatcccagcactttgggaagccaaggcagacagatcacctgaggtcaggagttcgagaccagcctgaccaacatggagaaaccctgtctctactaaaaatacaaaaattagccgggcgtggtgctactcgtgaggctgaggcaggagaatcgcttgaacccgggaggtggaggttgcggtgagctgagatcgtgccattgcactccagcctgggtaacgagcaaaactccgtctcaaaaactccgtctcaaaaaaaaaaaaTCCTTGATTACATTGTTAGTAAGGACTGTGTTACGATTATAAACACATTTATTGGTTGATGTCAAATTCACTGTAATAGTAGAACTAAGTTTTTTATGTGAGTACTTTGCCCTACTGTCTATATGATGACATCTTTTTTGAGCAGCTAAATTTTAAATTGTATATACTTTATTTTGTGAATCCTTGTTGAATGTGCTAAAGGTTTCTTTGTGTAGTTCTTCCATGCTATGCGAATATTTTAGTAAAAGTAGTTGATTTTTA

Publications

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