Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name OSBPL9P2
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:91113875-91115951  UCSC
Coordinates (hg19) chr11:90847043-90849119  UCSC
Strand -
Parental Sequence NM_148908.4
Parental seq. overlap 1602 bp
Parental seq. overlap (%) 43.9%
Genomic Region Intergenic
Retrocopy Summary OSBPL9P2, located on chr11:91113875-91115951, is a retrocopy of the parental gene OSBPL9. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name OSBPL9
Full Name oxysterol binding protein like 9
Also known as ORP-9|ORP9
Coordinate chr1:51617084-51789219
Strand +
Gene summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes OSBPL9P2
Bonobo Pan paniscus OSBPL9P3
Gorilla Gorilla gorilla OSBPL9P3
Orangutan Pongo abelii OSBPL9P4
Gibbon Nomascus leucogenys OSBPL9P3
Green monkey Chlorocebus sabaeus OSBPL9P1
Crab-eating macaque Macaca fascicularis OSBPL9P4
Rhesus Macaca mulatta OSBPL9P4
Baboon Papio anubis OSBPL9P4
Golden snub-nosed monkey Rhinopithecus roxellana OSBPL9P5
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>OSBPL9P2
CACACACACACACACCTGGTGCCAGATTTTTTCATAAATACTCTGCCTAATGTAAATATGGGTTCCTCTGAGTTGTTTTAGAAAATTACCGTAATGTATTAAAATCAAGTGTTAGGAAATGTCATGGTCTTACCTATAATAACTTTTATTTTAGAATTGGACTATTATTAGACTCTATCTAATCCTGGAACAGCAGCTCAGGAAATAGTCTAAAACATCCAGATACTAGAGAATCACTTAATTCTTCCATGTCCAATGGAACAAGTGATGCTGACCTTTTTGATTCATATGACAGTAGAGATGATGATGTGTAGGCGGGGTCCGCAGGGAGCACAAGAGCGTTATCATGCATCTCTTGTCACAGGTTAGGCTTGGGATGGATCTTACTAAGGTAGTTCTTCCAAGGTTTATTCTTGAAAGAACATCTCTTTTAGAAATGTAGGCAGACTTTTTGCACACTGGGACCTGTTTGTGTCCATTAGTGACTAGAAGGATCACAAGGATAGAATGGTTCTGGTTGTGAAATCATACCTCTCAGCCTTTCATGCAAGAAGGAAAGGGTCAGTTGCCAAAAAGCCATACAGTCCCATTTTGGGCAAGATTTTTCAGTGTCACTGGACACTACCAAATGATACTGAAGAGAACACAAAACTAGTTTCAGAAAGACCAGTTCCCTGGGTTTCCAAAAATACTGTAACATTCGTGGCTGACCAGATTTCCCATCATCCACCCATTTCAGCCTTTTATGTTGAGTATTTTAACAAGAAGATACAATTCACTGCTCATGTCTGGGCCAAATCAAAATTCCTTGGGATGTCAATTGGTGTTCACAACATAGGGCAGGGCTGTGTCTCATGTCTAGACTATGATGAACATTACATTCTCACATTCCTCAATGGCTATGGAAGGTCTATCCTCACATGGTCCTGGGTGAAATTAGGTGGAGAATGTTGTATTAATTGTTCCAAACAGGCTAGAGTGCAAATATCATCTTCCATACTAAACCCTTCTATGTGGGCAAGAAGCACAAAATTACTGCTGAGATTTTTTTCTCCAAGTGACAAGAAGTCTTTTTGCTCAACTGAAGGGGAATGGAATGGTTTGATGTATGCAAAATATGCAACATGGGAAAATACATCCTTTGCAGATACCAAGAAGTTGCCTGTAATCAAGAAGAAAGTGATGAAGCTAGAAGATCAGAACAAGTAAGAATCCCGCAGCCTTTGGAAGGATGTCACTTTCAACTTAAAAATCAGCAACTGAAGCAAAGCACAGGCTTGAATAAAAGAGCAGAACCCCAAGAAAGGAAAGAGGGAAAGAGAAAGAAATTCAGTGGGAGACAAGGTTATTTCATAAAGATGGAGAATATTGGGTTTATGATGAACCATTACTGAAATATCTTGGTGCTGCCAAGCATTAAGTTTGAAGATGCAAAGTATATACCTGATGATCAGGGCAGTAGACATAATTCAGCAACAAACAATCTTCCTTTGGGAGAAACCTGTTCACTACCTTCTTATTAGAGTGGTTCCTATCTCAGGGATACTGGACTTTTGGACTCAGATGAACAATTAAAGTGCAAAAAACTTCCCTTTTCCCTCTGTGGCAGTTATGATTTTGACTTCAGTCCTGAGAAAAACTTCAGGTTTTGAAAACGAGATGTCTGCTCCTTTTCCAAACCCCACACGTTGAAAATCATTTATAAATCCAAACCTGAAACTCTTTACTCTAGTACTGCTATTAAGATATACAACCTGTTTCTTAGTACATATAATCTTGAGATACGTACATGc
>NM_148908.4
GTCATTGGCGGCTCCCAAGATGGCGTCCATCATGGAAGGGCCGCTGAGCAAATGGACTAACGTGATGAAGGGCTGGCAGTACCGTTGGTTCGTGCTGGACTACAATGCAGGACTGCTCTCCTACTACACGTCCAAGGACAAAATGATGAGAGGCTCTCGCAGAGGATGTGTTAGACTCAGAGGAGCTGTGATTGGTATAGACGATGAGGACGACAGCACCTTCACAATAACTGTTGATCAGAAAACCTTCCATTTCCAGGCCCGTGATGCTGATGAGCGAGAGAAGTGGATCCATGCCTTAGAAGAAACAATTCTTCGACATACTCTCCAGCTTCAAGGTTTGGATTCAGGATTTGTTCCTAGTGTCCAAGATTTTGATAAGAAACTTACAGAAGCTGATGCTTACCTACAAATCTTGATTGAACAATTAAAGCTTTTTGATGACAAGCTTCAAAACTGCAAAGAAGATGAACAGAGAAAGAAAATTGAAACTCTCAAAGAGACAACAAATAGCATGGTAGAATCAATTAAACACTGCATTGTGTTGCTGCAGATTGCCAAAAGTACTATTAATCCCGTAGATGCAATATATCAACCTAGTCCTTTGGAACCTGTGATCAGCACAATGCCTTCCCAGACTGTGTTACCTCCAGAACCTGTTCAGTTGTGTAAGTCAGAGCAGCGTCCATCTTCCCTACCAGTTGGACCTGTGTTGGCTACCTTGGGACATCATCAGACTCCTACACCAAATAGTACAGGCAGTGGCCATTCACCACCGAGTAGCAGTCTCACTTCTCCAAGCCACGTGAACTTGTCTCCAAATACAGTCCCAGAGTTCTCTTACTCCAGCAGTGAAGATGAATTTTATGATGCTGATGAATTCCATCAAAGTGGCTCATCCCCAAAGCGCTTAATAGATTCTTCTGGATCTGCCTCAGTCCTGACACACAGCAGCTCGGGAAATAGTCTAAAACGCCCAGATACCACAGAATCACTTAATTCTTCCTTGTCCAATGGAACAAGTGATGCTGACCTGTTTGATTCACATGATGACAGAGATGATGATGCGGAGGCAGGGTCTGTGGAGGAGCACAAGAGCGTTATCATGCATCTCTTGTCGCAGGTTAGACTTGGAATGGATCTTACTAAGGTAGTTCTTCCAACGTTTATTCTTGAAAGAAGATCTCTTTTAGAAATGTATGCAGACTTTTTTGCACATCCGGACCTGTTTGTGAGCATTAGTGACCAGAAGGATCCCAAGGATCGAATGGTTCAGGTTGTGAAATGGTACCTCTCAGCCTTTCATGCGGGAAGGAAAGGATCAGTTGCCAAAAAGCCATACAATCCCATTTTGGGCGAGATTTTTCAGTGTCATTGGACATTACCAAATGATACTGAAGAGAACACAGAACTAGTTTCAGAAGGACCAGTTCCCTGGGTTTCCAAAAACAGTGTAACATTTGTGGCTGAGCAGGTTTCCCATCATCCACCCATTTCAGCCTTTTATGCTGAGTGTTTTAACAAGAAGATACAATTCAATGCTCATATCTGGACCAAATCAAAATTCCTTGGGATGTCAATTGGGGTGCACAACATAGGGCAGGGCTGTGTCTCATGTCTAGACTATGATGAACATTACATTCTCACATTCCCCAATGGCTATGGAAGGTCTATCCTCACAGTGCCCTGGGTGGAATTAGGAGGAGAATGCAATATTAATTGTTCCAAAACAGGCTATAGTGCAAATATCATCTTCCACACTAAACCCTTCTATGGGGGCAAGAAGCACAGAATTACTGCCGAGATTTTTTCTCCAAATGACAAGAAGTCTTTTTGCTCAATTGAAGGGGAATGGAATGGTGTGATGTATGCAAAATATGCAACAGGGGAAAATACAGTCTTTGTAGATACCAAGAAGTTGCCTATAATCAAGAAGAAAGTGAGGAAGTTGGAAGATCAGAACGAGTATGAATCCCGCAGCCTTTGGAAGGATGTCACTTTCAACTTAAAAATCAGAGACATTGATGCAGCAACTGAAGCAAAGCACAGGCTTGAagaaagacaaagagcagaagcccgagaaaggaaggagaaggaAATTCAGTGGGAGACAAGGTTATTTCATGAAGATGGAGAATGCTGGGTTTATGATGAACCATTACTGAAACGTCTTGGTGCTGCCAAGCATTAGGTTGGAAGATGCAAAGTTTATACCTGATGATCAGGGCAGTAGGCATAATTCAGCAACAAACAATCTTCCTTTGGGAGAAACCTGTTCATTCCAATCTTCTAATTACAGTGGTTCCTATCTCAGGGATACTGGACTTTCTGACGCAGATGAACAATTAAGGGGAAAAGCTTCCCTTTTCCCTCTGTGGCAGTTACGATTTTGACTTCAGTCCTGAGAAAAACTTCAGGTTTTGAAAATCAGATGATGTCTTCTCCTTTTCCAAACACCACACGTTGAAAGCATTTATAAATCCAAGTCTGAAACTCTGCGCTCTAGTACTGCTGTTAAGATACACAACTTGTTTCTTAGTTCATATAATCTCGGGATacacacacacacacacatatatatacacacacatacgtatacacacacatacatatatataaatataCCTGATGCCAGATTTTTTTCATAAATATTCTGCCTACTGTAAATATGGGTTCCTCTGAGTTGTTTTAGAAAATTAGCGCAATGTATTAAAATCAAGTGTTAGGAAATTTCATGGTCTTACCTACAATAACTTTTATTTTGGAATTGAACTATTATTAAATTGTATCTAATCCTGGATTACAGTTTAATTAATTATTCTTAGTGCTTAAGGCTTCATAAAGTAATTTTTCCAACCTTTTTTTTAAAAATGTGCATCTTTTATTATCTTTTATGGTTAAACTTGGAAGCCAATTATTTGGCAACCTTGAATACAAGAGCTAGCTTTTCAAAGAAAGACACTTGAAATAATGGAGGATCCATTCTTTTCCTCTGTCAGATTGTATGTTCTGTCTTTAGCCCCTGCCAGGCAATTCCCCAGAATCTTCACTTAACTCATATTGCACATGTAGGGCTGCCTACCAACATTTTATCCAAAAATGTTTTATTGCCTTAGAGGGTTTGGGAAGAGTGTGTATTTATAGATCCCCACCCCACAGTGAACAAAAATAGATAGATAGATAGAATAAAATGAATGCCACAGCAGCAGATGGCTCATTCTGAAGGGAAATACAGAACTAtatctatctatctatctatcatctTTTTTATTTAAAAATACATTAAAAAAACAGGTATTAGTACCTAGCATTTAGTTAGTTATTCAATATACTGGTTACGTAAGGCCTTTCAAGAAGTAGATTCTCAGTCTGAGAGGACACAGGCCAGGGCTTCTCAAAGTGCTGCTGCAGGCTTTCTGGTCTCGCTTGGCCCATTCTGCTAATTTTCCTTTGCCAGCTCCTACAGTAACCCTGGGTTTATTAGTCTCAACAAAGGATAAAAAGTAAATCAAATGCTATGATGCCAGTGCAAAACTTCAATGGAAGCCCTAAGGCAGTAGTATAACTAACTCCATAAAATACAAACAAACACATTTTAAAATACACATTGCTTCAGGCCAA

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