Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ARPC3P3
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:94188203-94189036  UCSC
Coordinates (T2T) chr11:94105089-94105922  UCSC
Coordinates (hg19) chr11:93921369-93922202  UCSC
Strand -
Parental Sequence NM_001278556.2
Parental seq. overlap 806 bp
Parental seq. overlap (%) 84%
Genomic Region Intergenic
Retrocopy Summary ARPC3P3, located on chr11:94188203-94189036, is a retrocopy of the parental gene ARPC3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ARPC3
Full Name actin related protein 2/3 complex subunit 3
Also known as ARC21|p21-Arc
Coordinate chr12:110434823-110450337
Strand -
Gene summary This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ARPC3P5
Bonobo Pan paniscus ARPC3P4
Gorilla Gorilla gorilla ARPC3P3
Orangutan Pongo abelii ARPC3P4
Gibbon Nomascus leucogenys ARPC3P3
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ARPC3P3
GATCCTGCTCCTCTGGGTTGAAACCCGGGCGCCGCCAAGATGCTGGCTTACCACTCTTCTCTCATGGATCCTGACATCAAACTCATCGGAAACAAGGCACTGTTGCCTATCAGAAGTCAATTCAAACGACCTGCCCCCAGAGAGACAAAAGATACAGATATTGTGGATGAAGCATCTATTACTTCAAGGCCAATATCTTCTTCAAAAACTATGAAATTAAGAATGAAGCTGATAGGACCTTGATAATATATAATGATATATATAACTCTCTACATTTCTGAATGTCTGAAGAAACTCCAAAAGTGCAATTCCAAAAGCCAAGGTGAGAAAGAAATGTATACACTGGGAATCACTAATTTTCCCATTCCTGGAAAGCCTGGTTTTCTACTTAACGCAATTTATGCCAAACCTGCAAACAAACAGGAAGATGAAGTGATGAGAGCCTATTTACAACAGCTAAGGCAAGAGACTGGACTGAGACTTTGTGAGAAAGTTTTCGACCCTCAGAATGATAAACCCAGCAAGTGGTGGACTTGCTTTGTGAAGAGACAGTTCATGAATAAGAGTCTTTCAGGACCTGGGCAGTGAAGGGAGCCCGGGCAGCCACCGTCTCCAGAGCCCTGGGCAGCATTTTCCATCAAGATGTACACAATCTTTTGCCTTTATTTCGTAAAGTTTTATACAGAAGAGAGAAGAGCATGTCTTTACTTGAAAAACTCTTGATCAAGAATTTGGGTGGGAGAAAAGAAAGTGGGTTATCAAGGGTAATTTGAAATTTTCTGCAGCATTAAGCTGGCGCTTAATAAGTAATAATAAAGAAATTTCTAACATTCA
>NM_001278556.2
GCCCAGGCTGCCAGACCGGAAGCGCTCCGCTGTACCTGGATCCTGCTCCTCTGGGTTGAAACCCGGGCGCCGCCAAGATGCCGGCTTACCACTCTTCTCTCATGGATCCTGATACCAAACTCATCGGAAACATGGCACTGTTGCCTATCAGAAGTCAATTCAAAGGACCTGCCCCCAGAGAGACAAAAGATACAGATATTGTGGATGAAGCCATCTATTACTTCAAGGCCAATGTCTTCTTCAAAAACTATGAAATTAAGAATGAAGCTGATAGGACCTTGATATATATAACTCTCTACATTTCTGAATGTCTGAAGAAACTGCAAAAGTGCAATTCCAAAAGCCAAGGTGAGAAAGAAATGTATACGCTGGGAATCACTAATTTTCCCATTCCTGGAGAGCCTGGTTTTCCACTTAACGCAATTTATGCCAAACCTGCAAACAAACAGGAAGATGAAGTGATGAGAGCCTATTTACAACAGCTAAGGCAAGAGACTGGACTGAGACTTTGTGAGAAAGTTTTCGACCCTCAGAATGATAAACCCAGCAAGTGGTGGACTTGCTTTGTGAAGAGACAGTTCATGAACAAGAGTCTTTCAGGACCTGGACAGTGAAGGGAGCCCGGGCAGCCACCGTCTCCAGAGCCCTGGGCAGCATTTTCCAGCAAGATGTACACAATCTTTTGCCTTTATTTCGTAAAGTTTTATACAGAAGAGAGAAGAGCATGTCTTTACTTGAAAAACTCTTGATCAAGAATTTGGGTGGGAGAAAAGAAAGTGGGTTATCAAGGGTGATTTGAAATTTTCTGCAGCATTAAAGCTGGCGCTTAATAAGAATAAGTAATAATAAAGAAATTTCTAACATTCCATGTCAGAAAAACTTTATTGCCAGTCTTTGACATTCACTTACAATTTGTTttgagataaaattcacattccataatgcc

Publications

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