Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SERF2P2
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:203353282-203353783  UCSC
Coordinates (T2T) chr1:202616151-202616653  UCSC
Coordinates (hg19) chr1:203322410-203322911  UCSC
Strand -
Parental Sequence NM_001199877.2
Parental seq. overlap 444 bp
Parental seq. overlap (%) 12.9%
Genomic Region Intergenic
Retrocopy Summary SERF2P2, located on chr1:203353282-203353783, is a retrocopy of the parental gene SERF2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SERF2
Full Name small EDRK-rich factor 2
Also known as 4F5REL|FAM2C|H4F5REL|HsT17089
Coordinate chr15:43777086-43796089
Strand +
Gene summary Involved in protein destabilization. Predicted to be located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SERF2P1
Bonobo Pan paniscus SERF2P1
Gorilla Gorilla gorilla SERF2P1
Orangutan Pongo abelii SERF2P2
Gibbon Nomascus leucogenys SERF2P4
Green monkey Chlorocebus sabaeus SERF2P9
Crab-eating macaque Macaca fascicularis SERF2P2
Rhesus Macaca mulatta SERF2P2
Baboon Papio anubis SERF2P1
Golden snub-nosed monkey Rhinopithecus roxellana SERF2P1
Marmoset Callithrix jacchus SERF2P8
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SERF2P2
GACAGAATGAGGTGACATAACAGAGGCAGGTCGGAGCCACTGCTGTCACCATGACCCGCAGTAACCAGCATGAGCTTACTGGCTAGAAAAATAGGAAAAAGCAGAGTGACTCAGTTAAGGGAAAACGTCGAGATGACGGGCTTTCTGCTGCTGCGGCAAGCAGAGGAGCTCAGAGACCAAGCAGCAGGAGCAGAAGAAGGCAAAAGAGAAGAAGGAGGAACCCGAGTAGCTTTGTGGCTTCATGTCCAACCCTCCTGCCCTTCGCCTATGTGACTGGAGCCAGTCCCACCACCCTCACGTTTCCTCCTGCAGTGCCCGCAGGTCCCCGCACCCATGGCCTCCTTTTGCCCTGAGTCTGCAGCGGGTCCCTTTTGTGCTTCCTTCCCCTCACGTAGCCTCTCTCCCCCTGGCCCCTCCTGGAAGTGGCGGGTGGGAGGTTACCCCTTCCCAGTGTTTTTTTATTCCTGTGGGGCTCACCCCAAAGTATTAAAAGTAGCTTTGA
>NM_001199877.2
GCTTCGCTCTCCCCGGCCAACCGCCCGGACCTCGGCGCTTTCTTCTAGGATCCGCATGAATCGCTTTGGGCTATCGGAAGAGCTATCCCCAGTTCTCGGGAGAAAGAGTCCGCGACCAGCGTCTGACCTCTCACTCAGAGTCCCCAGTCCTGCCTTAGTTTCCCCAGCGACCCTGAATTTGGAGTTGCTGTCTCTAAGTGAAAGCTGAACCTGCAACCCCTTGAGGGTTTCAGCCGCAGAGGGGCGGGAGAAAGGGCCTGGTTGGTAGGCGGGCTCAGCGGTTCGCGCCCAGTTAGCCCCGAGCTTCGGAGACCCGAGAGACCAGAGGATGGCTGACACGAAGGGGCACCCGAGACAGCGCCTGGGCTTTTTCCCGCCCGCGGTTCCACCGCTCTGAAACCGATTTCTAACAGAGAGagacatagtcttgctctgttacccatgctggagtacggtggcgagatcacgactcactacaactttgaattcctggattcaagcaatcctcccatctcagcctcctgagtagctaaggactacagGGCGACTTTGTCAGTACCCCAAACTGTCCCCGCATGAGGTCACTCTGCACGGTCACGTGCTCGAGCCCGCGGGAGCGCCACATCGCCAGCCGCACCCCTCCACCCCCAACCTGCCCACGTGACCCGGCCTAGTTTCTCCAGGCCCGTCCCTACGTCTCACTCGGGAAGCCCCGCCCCACGCTGAGCGCTCCGCCTGCGACCCTCCGCCACTTACCCACCCCGGCTCAAGCACGACCCGTGGATCCACGTGCTTTTTCTTGTCCAATGGGAGCCGGCTCCCGGGCGCGAAGGGGCGGGGAGGAAAGGAACGACTGTGCTACGTTGCCAGAAGGGGCGGGACCTGCAACGTCCGACAGAACGAGGGGACGTAACGGAGGCAGGTTGGAGCCGCTGCCGTCGCCATGACCCGCGGTAACCAGCGTGAGCTCGCCCGCCAGAAGAATATGAAAAAGCAGAGCGACTCGGTTAAGGGAAAGCGCCGAGATGACGGGCTTTCTGCTGCCGCCCGCAAGCAGAGGGACTCGGAGATCATGCAGCAGAAGCAGAAAAAGGCAAACGAGAAGAAGGAGGAACCCAAGTAGCTTTGTGGCTTCGTGTCCAACCCTCTTGCCCTTCGCCTGTGTGCCTGGAGCCAGTCCCACCACGCTCGCGTTTCCTCCTGTAGTGCTCACAGGTCCCAGCACCGATGGCATTCCCTTTGCCCTGAGTCTGCAGCGGGTCCCTTTTGTGCTTCCTTCCCCTCAGGTAGCCTCTCTCCCCCTGGGCCACTCCCGGGGGTGAGGGGGTTACCCCTTCCCAGTGTTTTTTATTCCTGTGGGGCTCACCCCAAAGTATTAAAAGTAGCTTTGTAATTCCTTGAGCGCCTGGTTTGACTGGGGACTTGGGGGGATGGGGTTGGAAGAATGACTGCCCTTTCCCACCAAAAAAGGGAGAACTCTTTAGATTCAGATTGTGGGTATGTAGACTTAATAAGTGAAACATCACAGAAGAAGCCTTTATTATACAATGACAACCAAACAAGTACTCCGGATATGCAGTAGAGGAATCCTCTAAGAACCATAGAGACTTCTTTTCTGTGATTTTTGTTCCCCACCCTTGAACACCATCTCTAGGATGGAGTTGGCCTAAGAGTGAATGCTGCAAGATCTGTGTTTATGCCTCTTTTCCTCATTCTTCCTCAGTTTGTTCGTCTGCTTGAAAGTTGGCCAAAAAATCCTGCTGCTCACCGACTTCCCGTGGTCAGCTGCTGTCAAGCGTTCACTTTCTCTTCTGTCATTCCTCATGGAATGAGGGTGGTTTTGTCTTCCCGCTTCCCTTGACCTCAAAATCAGGATTAAAACCTGGGGTAGCCTCTGTGCTCCTTTCTTCTATGCCCTGGTTTGTTCTGTGGTTCTGGGCTTCTTATATCCGTGTGCCCAGGGCTGAACTCCTTATTTTCCTTTCTCCAAGGGCAGAGCCGAGTCTTCAGTCCCTGTTGGTCTTTCCCCACCCCCACTTCCAGCCCAAGAGCCAGGAAAGGGCTGGTGCCACACTGTCTGCTGGGATCAGCGGTGGTTCTTTGAGCTGCTGATTTGGGTGTTAGGCTCTTGAGCTGGGATGCAGATGTAACAGTAGCTCCAGTGAGTCAGACACTCTGCCCAGCACATTAGACTGTGTTTGACCACTTCTTCCAGTTCATAGTATTGACTTCAGCCCAAACGGAGATAACTCCCTGTGTGTCCTTGAGGTATTGAGCTGGGCTGGACAGCTCCCCTTGAGCCAACTCTAGGAGTACAATGTCAGGGGAACCCCAGTTTGTGAAAAGGACTTAGACTGGAGGATATTTGTTATCTGGGGATATGATGCGGTGGCGGCGGCGCCTCAAGATAAGGGGCTGGGGTTTCTGGGTGGGGGGCCAACAGAGTGGTGCCAGTAACAGCCCCAGATAGAGGAGTACGCAGGCCCAGCATGAGGCAACCTTGACCCAGAAGGTGGCCCAGCTACCCTTGATGAAGGTCTTTTCCAGTTCTGCTCCCTCATAGCTGTGTAACCAAAGGCTCTGGTTAGAGAATATGAAGGGCCTTAGCTTTTAGACCTGTTCTACCTCCTCACCAAATATAATGGCAGACCCATGTGTGTCTGGAATGGCCTTGAATTGCTCTTTCCTTAAAATAGCTAGCTCTTCAGGAGAGTATCTAAGGCCCACTCCATCTTACCTGAACCAGTTGGTAAGGGTAACCATGACATAGAGTGAGGCAAGGAAGAAGACGAAGTGGAAGGCAGAATAGTTGTAGGAAAGATGCTGGACTTGGACTGGAGGAGCTGGAGGGGTTTCTTGGTCAGCTGGCCTCGCAGCCCCACCCCTTTGCCCTGGAGAGAGGAAATGGCTGCTGGGAGCAGAGCTGCTGAAACACCTCTTCCCCTCTCCCCCAACTACCTTTGTTAAGGCTCTTGAGGGTTCTTATGGCACTCCACAGAGATCTACCACTTCTTATGGTTCCTCACTTGGCACTCACCTTTGTCTGCCTCCACTGTTTCAGGGCAGCAGAAACACAGTGAGGGCTTCTGCAAAACAGAACGCAGGTTTTGGAATGGTCTTAAAAGATGTGAGGGTGTTAATCTAGGAAACTTCCCCCGTGAAAAGATtggtctagtattaaaaagtggaggcacacctgggttcaaattctagctccagcatataagtggctgtgcagactttggtaagatgtttaatcttttgtgcctcgatttctccatttgtaaaatggagcaaatacctacctcacagggttgttgtgagggttaaattaaatgagattatgtaaaagtatctagcacagttgcctagcacattgtgggtactcaataaaaggtaacAGCAGCTATAATCTGAGCATTCTGGGTA

Publications

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