Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PEF1P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:204528092-204529672  UCSC
Coordinates (T2T) chr1:203792489-203794069  UCSC
Coordinates (hg19) chr1:204497220-204498800  UCSC
Strand -
Parental Sequence NM_012392.4
Parental seq. overlap 1451 bp
Parental seq. overlap (%) 89.1%
Genomic Region Intragenic (MDM4)
Retrocopy Summary PEF1P1, located on chr1:204528092-204529672, is a retrocopy of the parental gene PEF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PEF1
Full Name penta-EF-hand domain containing 1
Also known as ABP32|PEF1A
Coordinate chr1:31629866-31644876
Strand -
Gene summary This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PEF1P1
Bonobo Pan paniscus PEF1P1
Gorilla Gorilla gorilla PEF1P1
Orangutan Pongo abelii PEF1P1
Gibbon Nomascus leucogenys PEF1P1
Green monkey Chlorocebus sabaeus PEF1P1
Crab-eating macaque Macaca fascicularis PEF1P1
Rhesus Macaca mulatta PEF1P1
Baboon Papio anubis PEF1P1
Golden snub-nosed monkey Rhinopithecus roxellana PEF1P1
Marmoset Callithrix jacchus PEF1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PEF1P1
GGGCTGCCCTGGAGATGCAGGGCAAGCGCCAGGAACCCCTCCGGGTAGCTACTACCTTGGACCCCCCCCAGTAGTGGAGGGCAGTATGGCAGCGTGCTACCCCCTGGTGGTGGCTATGGGGGTCCTGCCCCTGGAGGGCCTTATGGACCACCAGCTGGTAGAGGGCCCTATGGACACCTCAATCCTGGGATGTTCCCCTCTGGAACTCCAGGAGGACCAAATGATGGTACAGCTCCAGGGGGCCCCTATGGTCAGCCACCTCCAAATTCCTACGGTGCCCAGCAGCCCAGGCCTCATGGACAGGGTGGCTCCCCTCCCAATATGGATGAGGCCTACTCCTGGTTCCAGTCGGTGACTCTGATCACAGTGGCTTTATCTCCATGAAGGAGGTGAAGCAGGCTCTGGTCAACTGCAACTGGTCCTTGTTCAATGATGAGACCTGCCTCATGATGATAAACATGTTTGACAAGACCTAATCAGGCCACATAAATGTCTACGGCTTCTCAGCCCTGTGGAAATTCATCCAGCAGTGGAAGCAGCTCTTCCAGCAGTTATGACTGGGACAACTCAGGCTCCATTAGCTACACAGAGCTGCAGCAAGCTCTGTCCCAAATGGGCTACAACCTGAGCCCCCAGTTCACCCAGCTACTGGTCTCCAGCTACTGCCCACGCTCTGTCAATCCTGCCAGACAGCTTGATTGCTTCATCCAGGTGTGCACCCAGCTGCAGATGCCGACAGAGGCCTTCCGGGAGAAGGACACAGCTGTACAAGGCAACATTCGGCTCAGCTTCAAGGACGTCGTCACCATGACAGCTCGGATGCTATGACCCAACCCATCTGTGGAGAGTGGAGTGCACCAGGGACCTTTCCTGGCTTCCTAGAGTGACAGAAGTACGTGGACCTCTCTCTTCTTTTCCTGTCCCTCTAGAAGAACATTCTCCCTTGCTTGATGCAACACTGTTCCAAAAGAGGGTTGAGAGTCCTGCATCACAGCCACCAAATAGTGAGGACCAGGGCTGAGGCCACACAGGTAGGGGCCTGATGAAGGAGAGGATGAAAGCTGAATGTCCCGACGGCCATGAGCAGTTGAGTGGCACAGCCTGGCACCAGACGCAGGAGATTCTGGTCCTTGTAATGGAGTTAGTGTCCAGTCAGCTGAGCTCCACCCTGATGCCAGTGGCGAGTGTTCACTGGCCTGTTACCATTAGCACCTGTGTTCCCTCACCAGGCCATCCTGTCACATGAGCCCATTTTCTCCAAAGTGGAATCTGACCAAGCATGAGAGAGATTTGCCCCTGGGACCAGTGGCTTGGATTCCATCACACCCATAAATCCTTGGGTATTAACTTCTAGCTGCCTGGGGCTGGCCCTGCTCAGACAAATCTGTTCCCTGGGCATCTTTGGCCAGGCTACTGCCTCCGCAGCTGGGATCCCTCACTTGCCTGCCACGCTCTGCTCGGCTTCCATCTCCAGGGGACAGTGGTCACCTCTCCTTGCCAATACTTTTTTTAATTTGCATTTTTTTCATTTGGGGCCAAAAGTTCAGTGAAATTGTAAGCTTCa
>NM_012392.4
GTCAGAATCACCATGGCCAGCTATCCTTACCGGCAGGGCTGCCCAGGAGCTGCAGGACAAGCACCAGGAGCCCCTCCGGGTAGCTACTACCCTGGACCCCCCAATAGTGGAGGGCAGTATGGTAGTGGGCTACCCCCTGGTGGTGGTTATGGGGGTCCTGCCCCTGGAGGGCCTTATGGACCACCAGCTGGTGGAGGGCCCTATGGACACCCCAATCCTGGGATGTTCCCCTCTGGAACTCCAGGAGGACCATATGGCGGTGCAGCTCCCGGGGGCCCCTATGGTCAGCCACCTCCAAGTTCCTACGGTGCCCAGCAGCCTGGGCTTTATGGACAGGGTGGCGCCCCTCCCAATGTGGATCCTGAGGCCTACTCCTGGTTCCAGTCGGTGGACTCAGATCACAGTGGCTATATCTCCATGAAGGAGCTAAAGCAGGCCCTGGTCAACTGCAATTGGTCTTCATTCAATGATGAGACCTGCCTCATGATGATAAACATGTTTGACAAGACCAAGTCAGGCCGCATCGATGTCTACGGCTTCTCAGCCCTGTGGAAATTCATCCAGCAGTGGAAGAACCTCTTCCAGCAGTATGACCGGGACCGCTCGGGCTCCATTAGCTACACAGAGCTGCAGCAAGCTCTGTCCCAAATGGGCTACAACCTGAGCCCCCAGTTCACCCAGCTTCTGGTCTCCCGCTACTGCCCACGCTCTGCCAATCCTGCCATGCAGCTTGACCGCTTCATCCAGGTGTGCACCCAGCTGCAGGTGCTGACAGAGGCCTTCCGGGAGAAGGACACAGCTGTACAAGGCAACATTCGGCTCAGCTTCGAGGACTTCGTCACCATGACAGCTTCTCGGATGCTATGACCCAACCATCTGTGGAGAGTGGAGTGCACCAGGGACCTTTCCTGGCTTCTTAGAGTGAGAGAAGTATGTGGACATCTCTTCTTTTCCTGTCCCTCTAGAAGAACATTCTCCCTTGCTTGATGCAACACTGTTCCAAAAGAGGGTGGAGAGTCCTGCATCATAGCCACCAAATAGTGAGGACCGGGGCTGAGGCCACACAGATAGGGGCCTGATGGAGGAGAGGATAGAAGTTGAATGTCCTGATGGCCATGAGCAGTTGAGTGGCACAGCCTGGCACCAGGAGCAGGTCCTTGTAATGGAGTTAGTGTCCAGTCAGCTGAGCTCCACCCTGATGCCAGTGGTGAGTGTTCATCGGCCTGTTACCGTTAGTACCTGTGTTCCCTCACCAGGCCATCCTGTCAAACGAGCCCATTTTCTCCAAAGTGGAATCTGACCAAGCATGAGAGAGATCTGTCTATGGGACCAGTGGCTTGGATTCTGCCACACCCATAAATCCTTGTGTGTTAACTTCTAGCTGCCTGGGGCTGGCCCTGCTCAGACAAATCTGCTCCCTGGGCATCTTTGGCCAGGCTTCTGCCCTCTGCAGCTGGGACCCCTCACTTGCCTGCCATGCTCTGCTCGGCTTCAGTCTCCAGGAGACAGTGGTCACCTCTCCCTGCCAATACTTTTTTTAATTTGCATTTTTTTTCATTTGGGGCCAAAAGTCCAGTGAAATTGTAAGCTTCAATAAAAGGATGAAACTCTGGA

Publications

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