Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CELF4P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr18). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:104146324-104147599  UCSC
Coordinates (T2T) chr12:104108024-104109299  UCSC
Coordinates (hg19) chr12:104540102-104541377  UCSC
Strand -
Parental Sequence NM_001353726.2
Parental seq. overlap 1102 bp
Parental seq. overlap (%) 28%
Genomic Region Intergenic
Retrocopy Summary CELF4P1, located on chr12:104146324-104147599, is a retrocopy of the parental gene CELF4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CELF4
Full Name CUGBP Elav-like family member 4
Also known as BRUNOL4|CELF-4
Coordinate chr18:37243040-37565798
Strand -
Gene summary Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CELF4P1
Bonobo Pan paniscus CELF4P1
Gorilla Gorilla gorilla CELF4P1
Orangutan Pongo abelii CELF4P1
Gibbon Nomascus leucogenys CELF4P1
Green monkey Chlorocebus sabaeus CELF4P1
Crab-eating macaque Macaca fascicularis CELF4P1
Rhesus Macaca mulatta CELF4P1
Baboon Papio anubis CELF4P1
Golden snub-nosed monkey Rhinopithecus roxellana CELF4P1
Marmoset Callithrix jacchus CELF4P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CELF4P1
CACCCTGTGCCCTCAAGCTGCCAGGCCCCCTCCTGTCAGGGAGGACAGTGTCCAATAAACTCCTCCACCCACAGGCTTCCTGAGCTTCGACAACCCGGCCAGCGTGCAGACCGCCATCCAGGCCATGAACGGCTTCCAGGTCAGCATGAAGAGGCTCCAGGTGCAGCTGAAGCGGCCCAAAGGCACCAGTTGCCTGGACTGAGCACCCGTGGGAGCATCTCCCGCGGGAGAGCAGGACTCGAACAGGGCAGGATGCTGAACGGGCTCCCTTTAAAAACCTGCACATGTATATCGGAACTTCAAACCAAATTAAATAAATAAACAAATCTCTCTCTATTTATAAATGAGAACTGTTGGATGACACCCTTGACATATTAGCCGATATCAATCAAGCTGAAGACTCCAGACACTGTCTGTGTGACTCTAACATTTCTTCAAGAAAAAGAGCATTTATGGAGTTAAGAGGTCACATATTTGGGGGAATATGTATGACATAAATAAGAAGATGAAGAAAAATGAAAAAAAACCCACACGCACACACACATAGCAACTTTAAAACAAAATAACACGAGACCAGACGTGAGGCTGAAGGGCTGGGAACTGGTAGGAGAGGCTGCTTTTCCAGCCTACAAGCACCTGAAGCAGGCCTGGTCCACAGGGGATAGCTGGGAGGCCACTGAGCATCTCTATCTGTCGTTCTTTCAGCTATTTAGGGACCAAAGGACCAGACTTTTTATGGCAGCTCTATGTGTAGCCCTGTGTCAAATGGAGGGGGAATGGAGGACAACCTCCTTCCTGTCTCGTGGCTGTTCTTGACACAGCTTAGAGCGATTCTACAAAAAAAGTAATAAAAAAATTTAAAAAAAGGAAAAACAACCTGTCACTGCCTTTCAAACAGCAAGATAATAGTTCTTTGATAATTTGAGAGGCGCTTTGATGAACTTTGAGAGGTGCTGTGACACTTTCCTATGGTTTTTTGTATTCTATGTCTGGATGGAGCTGTTAAGATGAACAAATTGGTGGATATTTGGGGAAAGCAACACAAATCTTAAAACTCATTAACTGCAAAGTGTGAGAAAACAAGGAGGGGAAAAAAGGGACTTACCAGGCAGGGTCATTGTTGTGAAAAGTCTGTAAATGCTTCTAACTCTTCCCCTTCTTAAAATCATAATAGTTGTAGAGAATTTTAAAAAGGAAAAGCCTAAAATACCTATATAATAGAAGAAAAATAGAGAAAAGCAAAATAAATAAATAGATAAAAATGGAAAAAAAAAAa
>NM_001353726.2
gagagagcagagagcgagcggagagcgaggtgtagagaaaccgagggggagagaacccgagtgtgtgtatgcgtgtgcgtgtgtgagcgcgagcgagcgagagagaggagcgagagagtgtgagcgagaaagaATAAAAGGAAAGAAGATTTTCTCTATGTATATAAAGATGGCCACGTTAGCAAACGGACAGGCTGACAACGCAAGCCTCAGTACCAACGGGCTCGGCAGCAGCCCGGGCAGTGCCGGGCACATGAACGGATTAAGCCACAGCCCGGGGAACCCGTCGACCATTCCCATGAAGGACCACGATGCCATCAAGCTGTTCATTGGGCAGATCCCCCGCAACCTGGATGAGAAGGACCTCAAGCCCCTCTTCGAGGAGTTTGGCAAAATCTACGAGCTTACGGTTCTGAAGGACAGGTTCACAGGCATGCACAAAGGCTGCGCCTTCCTCACCTACTGCGAGCGTGAGTCAGCGCTGAAGGCCCAGAGCGCGCTGCACGAGCAGAAGACTCTGCCCGGGATGAACCGGCCGATCCAGGTGAAGCCTGCGGACAGCGAGAGCCGAGGAGATAGAAAACTCTTCGTGGGCATGCTCAACAAGCAACAGTCCGAGGACGACGTGCGCCGCCTTTTCGAGGCCTTTGGGAACATCGAGGAGTGCACCATCCTGCGCGGGCCCGACGGCAACAGCAAGGGGTGCGCCTTTGTGAAGTACTCCTCCCACGCCGAGGCGCAGGCCGCCATCAACGCGCTACACGGCAGCCAGACCATGCCGGGAGCCTCGTCCAGTCTGGTGGTCAAGTTCGCCGACACCGACAAGGAGCGCACGATGCGGCGAATGCAGCAGATGGCTGGCCAGATGGGCATGTTCAACCCCATGGCCATCCCTTTCGGGGCCTACGGCGCCTACGCTCAGGCACTGATGCAGCAGCAAGCGGCCCTGATGGCATCAGTCGCGCAGGGCGGCTACCTGAACCCCATGGCTGCCTTCGCTGCCGCCCAGATGCAGCAGATGGCGGCCCTCAACATGAATGGCCTGGCGGCCGCACCTATGACCCCAACCTCAGGTGGCAGCACCCCTCCGGGCATCACTGCACCAGCCGTGCCTAGCATCCCATCCCCCATTGGGGTGAATGGCTTCACCGGCCTCCCCCCACAGGCCAATGGGCAACCTGCTGCGGAAGCTGTGTTCGCCAATGGCATCCACCCCTACCCAGCACAGAGCCCCACCGCCGCGGACCCCCTGCAGCAGGCCTACGCCGGAGTGCAGCAGTATGCAGGTCCAGCTGCCTACCCTGCTGCCTATGGTCAGATAAGCCAGGCCTTTCCTCAGCCGCCTCCAATGATCCCCCAGCAGCAGAGAGAAGGGCCCGAGGGCTGTAACCTGTTCATCTACCATCTGCCCCAGGAGTTTGGGGACGCTGAGCTGATGCAGATGTTCCTCCCTTTCGGCCGGCACCCTGTGCCCGCGCGCTGCCAGGCCCCCTCCTGTCAGGGAGGACAGTGTCCAATAAACTCCTCCACCCGCAGGCTTCGTGAGCTTCGACAACCCGGCCAGCGCGCAGACCGCCATCCAGGCCATGAACGGCTTCCAGATCGGCATGAAGAGGCTCAAGGTGCAGCTGAAGCGGCCCAAAGACGCCAATCGCCCGTACTGAGCGCCGGCGGGAGCGTCCCCCGGGGGAGACCAGGACTCGCACAGGGCAGGATGCTGAACGGGCTACATTAAAAAACAAACCTCTCTCTATATATATTTATAAATGAGAACTGTTGGATGACACCTTTGACATATCAGCCAATATCAATCAAGCTGAAGACTCCAGACACTGTCTGTGTGACTGTAACATTTCTTCAAGGAAAGTATAGCGTCTATGGAGTTCAGAGGGCACGTGTTTGGGGGAAAATATATATGACATgaagaagaagatgaagaaaaatgagaaaaaAACACACAAAAGGCAACTTTAAAACAAAATATCACGAGCAGACGGGGAGGCTGAAGGGCTGGGAGCTGGGAGGAGACGCTGCTTACCGATCCCGGGGCTTTTCCAGCCCACGGGCGCCTGACGCAGGCTGGGGCAAGTGGTGCGTGGGGCCTGGTCCCCAAGGGGCGGCTGAGAGGCCGCCACTGAGCATCTCTATCTGTCATTCCTTTAGCTATTTAGGGACCAAAGGACCAAACTTTTTATTGCAGATGTGTAGCTCTATGTCAAATAGAGGGGGAATGGAGGACCCCCTCCTTCCTGCCTCATGGCTGTTCTTGAAACAGCTTAGAGCGATTCTATGaaaaaatgtaataaaaaattaaaaaaaaaacaaaaaacaaaaaaaacaacaaaaaaaggaaaaataaCGCTTCAATGCTTTTAAAACAGCAAGATAATAGTTCTTTGATACTTTGAGAGGCGCTTTGATGACCCTCATCCAAGTCTATGACACTTTCCTATGGTTTTCTGTATTCTATGTCTGGATGGAGCTGTTAAAAGATGAACAAATTGGTGGATATTTGGGGAAAGCAACACAAATCTTAAAACTCACCCGTGAAGTGTGAGAAAACAAGGAGGGGAACAAATGGGACTTACCAAGCAAGGTCATTGTTGTGAAAAGTCTGTAAATGCTTCTAACTCTTCCCCCTCTTAAAATCATAATAGTTGTACAGAATTTTAAAAAGGAAAAGTTTAAAATACCTATATAATAGaagaaaaattagaggaaagcaaaaaataaaaaaaaaaaataaaaaaggaaaaaaaaaaCCTATAGAAGTTAGCATTACTGCTAAAATCCCAGATGTTGTAGGACTGTACTTTTGTAGAGTTTAGACAGAGCATCAATCCCTTCTCCCCGCGAGTGCAGTCGGATGCCGTTGTCCCCAAGGGCCAGGCCGAACTCGCCCCACACCTGCGGGCGCCTGGCTGCCGACGCCGGTGGAGGCCACGCCGTCGGTCGGGAACGGTCGCGTCGCCCGGGTcgccgccgccgccgccgccgTCATCCTCGCCTCTCGCTTCCCTCTGGGAGCTGCGCGCGCTTCACTCACCTTCCGCTTCACTCGCCTTCCACGCTTGCTCCAGAGACTTTCCGGGCAAGGGAGAACTGGGAACTTTCATCTTAAAACAACTAGACAACACACACACACACAAAACCTTAAAAAAGAGAGAGAAAAATAAACAATCTTTGAAGAATTTCTGAAACTGTTTACAAGGAATTTTGAAAAACAGGGATGTTTAAATGATGCCGGCTCTGTTTTTCTGTAAATAAATTTGCATATTTTGTAGGACTTTTAATTGTAATGATAGAGAAAAAAACAAGGAAAACTATTTAATGAAAGCACGATATTTATCTTTGGTAAATGACTTTAGAGCAGTTAAAGACATTGCTTAAAAAACTCAGAATCAGAAAAAACACTGAATTATTTAAGAACACATATATTTTAAAGTATAACATATTTATTATAATTTATTTGCACCCTTGGGAAGATTGCTTTGGCATTCTGCCTTGATTCCTTCTCATTGATGTCCAGGTCATCTGGAGGCCGGGGGTTCTCAGACCTACCAGTTTCCCTTTAGAAGAACAAATTTCCAGTTCCTCTAGGGCCTCCTGCCTTTCCtttctttctgtcaattttgttgttgttgttgtttttcattttctttttTTCTCTTGACTCCTCCTTTTAGGATGTCCAGATGTaaaaaaaaaaaaaaaaaaaagaaaaaaagaaaaaaaaaagaaaaCAGCTGCAGTTCAGTACAACTGCTCTTTTCACACTCAACTCCCTAAAACTCCTTGTAACCTTCTGTAACTATTGGATGACGCTTTCTCCAGCTTAGCCCTAAATAAAGCACAGTTTAAAAAAA

Publications

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