Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZNF717P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:114929755-114929973  UCSC
Coordinates (T2T) chr12:114907816-114908034  UCSC
Coordinates (hg19) chr12:115367560-115367778  UCSC
Strand -
Parental Sequence NM_001290210.2
Parental seq. overlap 187 bp
Parental seq. overlap (%) 16.1%
Genomic Region Intergenic
Retrocopy Summary ZNF717P1, located on chr12:114929755-114929973, is a retrocopy of the parental gene ZNF717. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZNF717
Full Name zinc finger protein 717
Also known as OB1|X17|ZNF838
Coordinate chr3:75729961-75785578
Strand -
Gene summary This gene encodes a Kruppel-associated box (KRAB) zinc-finger protein, which belongs to a large group of transcriptional regulators in mammals. These proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation and apoptosis, and in regulating viral replication and transcription. A pseudogene of this gene was identified on chromosome 1. [provided by RefSeq, May 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ZNF717P1
Bonobo Pan paniscus LOC100977879P1
Gorilla Gorilla gorilla ZNF717P1
Orangutan Pongo abelii LOC100458450P1
Gibbon Nomascus leucogenys LOC100588139P1
Crab-eating macaque Macaca fascicularis ZNF717P1
Rhesus Macaca mulatta LOC694533P1
Green monkey Chlorocebus sabaeus Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZNF717P1
TGTTTCCAAAAGCAAAAGAAATGAATACATTTCTGGTGTTGGTGTTGTTTGAGGATGTGGCTAAGGACTTCACTTGGGAGGAGTGACCAGATCTGGATGATGCTTAGCAGACCCTGTACAGAGACATGATGCTGGAGACCTACAGCAGCTTGGTATCCTTGGGACACTGCATTACCAAACCTGAGATTATCTTCTGGAGCAAGGATCAGAGCCATGGAC
>NM_001290210.2
CTTGTAGCTGGGCCAGCCTGGGGCTTGGTTCTATGTCCCTGCGGGTCGGTGCGAGGGCGAAGAGGAACCCGTGGGCCCGGGGGATCCCGGGGGGCCGGACCAGTGTTCCCCAGTTGTGGGAGCAGACGCGTGGGCGCATCGCGGGCGGGCAGGGCCTGAAGTGCAGCTATGTTTCCAGTGTTCTCTGGCTGTTTCCAAGAGCTACAAGAAAAGAATAAATCTCTGGAGTTGGTGTCCTTTGAGGAGGTAGCTGTGCACTTCACCTGGGAGGAGTGGCAGGACCTGGATGATGCTCAGAGGACCCTGTACAGGGACGTGATGCTGGAGACCTACAGCAGCCTGGTATCATTGGGGCATTACATTACCAAACCTGAGATGATCTTCAAGCTAGAGCAAGGAGCAGAGCCATGGATAGTAGAAGAAACCCCAAACCTGAGACTTTCAGgtggaagcaagaagcaagttttctcaggtatttgccacaggagcctggtggagctccaggaggtttgatctctcttgtgaactctggaactgtattcccaattgtcaattggacatccctacgtatgggacctcagatatttcaaacatgatgtgtccaagtctgTATCACTTCTGGCCATCATATTGTTCTTTTATTTTTCCAAATTTCACATCACCAGTAACAAACTAGCTGTGATCATGGCAGATAGCCTGGAAATAAAACTCCCCTTTTTACCCTTTGCACAGCAAATTGACATCAAATCCTGTTTCTACTTTTTTTTTTTTTAACTATTGCTTCCCTATTCTGTATTCTCACTGCTCCATCTCCTGATGTAGGAGGTCATCTGTTTTCCTCTTTTCCTCTCCTCTGACTCTTAAGCCCTTTCCCATTCTCTTTCTCAGGAATGGCTGTTAAAATGCCAATATGGTCTTGTAACTTTCCTGTACTTAGTGAACCTCCTTATTTACACCCTGTTTGTGAAGTGGCTGTGTTCACCCTGGGTGGACACGGAATGTTTTTGTCATGTACAAAGAGAATTTTATGCTGCCTGTGTACAGTTATTAATTTGTAAGTAcactcagctttttgtatctgtaggtttaatatctgtgtatgtaagcaaacttggatgcaaaatatttgaaataaaatcagatgcttgcatctgtagtgaacata

Publications

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