Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DDX55P1
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Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:11512729-11514338  UCSC
Coordinates (T2T) chr12:11381907-11383516  UCSC
Coordinates (hg19) chr12:11665663-11667272  UCSC
Strand +
Parental Sequence XM_024449105.1
Parental seq. overlap 1347 bp
Parental seq. overlap (%) 47.3%
Genomic Region Intergenic
Retrocopy Summary DDX55P1, located on chr12:11512729-11514338, is a retrocopy of the parental gene DDX55. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DDX55
Full Name DEAD-box helicase 55
Also known as -
Coordinate chr12:123602089-123620943
Strand +
Gene summary This gene encodes a member of protein family containing a characteristic Asp-Glu-Ala-Asp (DEAD) motif. These proteins are putative RNA helicases, and may be involved in a range of nuclear processes including translational initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Multiple alternatively spliced transcript variants have been found for this gene. Pseudogenes have been identified on chromosomes 1 and 12. [provided by RefSeq, Feb 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DDX55P1
Bonobo Pan paniscus DDX55P2
Gorilla Gorilla gorilla DDX55P1
Gibbon Nomascus leucogenys DDX55P1
Green monkey Chlorocebus sabaeus DDX55P1
Crab-eating macaque Macaca fascicularis DDX55P1
Rhesus Macaca mulatta DDX55P1
Baboon Papio anubis DDX55P2
Golden snub-nosed monkey Rhinopithecus roxellana DDX55P1
Orangutan Pongo abelii Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.20.4
log10(TPM+1)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>DDX55P1
AGTTTAAGCAACAAGGTGGGAACATCACTGTGGCCATTCCAGGCCACTTGAAGACAGGTTCTGAAGGAAGGCAGAAGGCTTGTATCTGGCCAGCTGTGTGTGATCCCTGCATATCCTGGTGTTGGATGAGGCAGACAGACTTCTGGACATGGGATTTGAGGCAAGCATAAATACCATCCTGGAGTTTTTGCCAAAGCAGAGGAGAACAGGCCTTTTCTCTGCCACTCAGAAGCAGGAAGTGGAGAACTTGGGGAGAGTGGGATGCCGGAACCCTGTCCAGTCTCAGTGAAGAAGGGTGTGGCAGCCAGCAGTGCCCAGAACACCACTCTCCCCTGGAAAACTACTACATGGTATGCAAGGCAGATGAGAAATTTAATCAGCTGCTACATTTTCTTCGCAGTCATAAGCAAGAGCAACACCTGGTCTTCTTTAGCACTTGCACCTGTGTGGAATACTACAGGAAGGCTCTGGAGGTGCTGATGAAGAGTGTGAAGATTGTGTGCATCCATGGAAAGATGAAATACGATCTTCAtTAGTGTGCACTGATGTGGTGGCCCAGGAATCAATGTTCCTGAAGTAAACTGGGTTTTGCAGTACAATCGCCCCTACAATGCAAGTGCCTTTGTGCAGCACTGTAGCCGCACAGCCCTCATTGGCCACAGAGGCAGAGCTCTGGTGTTCCTCCTGCCCGTGGAAGAGTCATACATCAATTTCCTTGCAATTAACCAAAAATGCCCCCTGGCGGAGATGAAACTCTAGAAAAACACAGCTGACCTTCTGCCAAAACTCAAGTCCATGACCCTGGCAGAAAAATCTGTGTTTGAAAAGGGCATGAAAGCTTTTGTGTCCTATGTCCAGGCTTATGCAAAGTAAGAATGCAACCTGATTTTCAGATTAAATAATCTTGATTTTGCAAGTCTTGCTCGAGGTTTTTCCCTGCTGAGAATGCCCAAGATGCCAGAATTGAGAGGAAAGCAGTTTCCAGATTTTGTGCCTGTGGACATTAATACAGACACTATTTCATTTAAAGATAAAATTAGAGAAAAGCAGAGGCAGAAATTACTGGAGCAACAAAGGAAAGAGAAAAACAGAAAATGAAGGGAGAAGAAAATTCATAAAAAATAAAGATTGGTCGAAGCAGAAGGCCAAAAAAGAGAAGAAGAAAAACATGAATGAGATAAGGAAAAGGGAAGCATGTTCTGATACAAAGATGAGGACATGGAAGAACTTCTCAATGATTCAGAGCTCTTGAAAAAAATTTTTAAAGGCAAAATTACTGAAGAATTTGAGAAGGACTTATTGACAAGTGGCAAAAGAACAATCAAGACAGCCAATTTAATGTCTCAGATTTGGAAGATGACTGCTAATACCAGGGCCACAGATAAACCCATAAGGGCATAGCTGTTTCCTAACTTGGTGGATGATTCCTATTTGCTTTTACCGCAAATCAAAACTTCAGGAGACATCTGAGAAGAATTACATCTCTGAAAGCTCTCCTTTCAGACTAGGGAGAAATGAGGGATTTCACACTCATGAATATTTGACTAAAAACATTCCAGTCTTG
>XM_024449105.1
GCGCGTTCGAGCAGCGGCGACCGACGCGGCGAAGGAGCGCGCCATGGAGCATGTGACAGAGGGCTCCTGGGAGTCGCTGCCTGTGCCGCTGCACCCGCAGGTGCTGGGCGCGCTGCGGGAGCTGGGCTTCCCGTACATGACGCCGGTGCAGgttggagtgcaatgacacgatctcggctcactgcaacttctgcctcccgggttcaagctattctcccatctcagccttccaagtagctggggttacaggcatacaccaccacgcctggctaatttttgtgtttttagtagagacgggatttcgccatgttggccagactggtcttgaactcctgacctcagTCCGCAACCATCCCTCTGTTCATGCGAAACAAAGATGTCGCTGCAGAAGCGGTCACAGGTAGTGGCAAAACACTCGCTTTTGTCATCCCCATCCTGGAAATTCTTCTgagaagagaagagaagttaaaaaagagTCAGGTTGGAGCCATAATCATCACCCCCACTCGAGAGCTGGCCATTCAAATAGACGAGGTCCTGTCGCATTTCACGAAGCACTTCCCCGAGTTCAGCCAGATTCTTTGGATCGGAGGCAGGAATCCTGGAGAAGATGTTGAGAGGTTTAAGCAACAAGGTGGGAACATCATTGTGGCCACTCCAGGCCGCTTGGAGGACATGTTCCGGAGGAAGGCCGAAGGCTTGGATCTGGCCAGCTGTGTGCGATCCCTGGATGTCCTGGTGTTGGATGAGGCAGACAGACTTCTGGACATGGGGTTTGAGGCAAGACGCAGGAAGTGGAGAACCTGGTGAGAGCGGGCCTCCGGAACCCTGTCCGGGTCTCAGTGAAGGAGAAGGGCGTGGCAGCCAGCAGTGCCCAGAAGACCCCCTCCCGCCTGGAAAACTACTACATGGTATGCAAGGCAGATGAGAAATTTAATCAGCTGGTCCATTTTCTTCGCAATCATAAGCAGGAGAAACACCTGGTCTTCTTCAGCACCTGTGCCTGTGTGGAATACTATGGGAAGGCTCTGGAAGTGCTGGTGAAGGGCGTGAAGATTATGTGCATTCACGGAAAGATGAAATATAAACGCAATAAGATCTTCATGGAGTTCCGCAAATTGCAAAGTGGGATTTTAGTGTGCACTGATGTGATGGCCCGGGGAATTGATATTCCTGAAGTCAACTGGGTTTTGCAGTATGACCCTCCCAGCAATGCAAGTGCCTTCGTGCATCGCTGCGGTCGCACAGCTCGCATTGGCCACGGGGGCAGCGCTCTGGTGTTCCTCCTGCCCATGGAAGAGTCATACATCAATTTCcttgcaattaaccaaaaaTGCCCCCTGCAGGAGATGAAGCCCCAGAGAAACACAGCGGACCTTCTGCCAAAACTCAAGTCCATGGCCCTGGCTGACAGAGCTGTGTTTGAAAAGGGCATGAAAGCTTTTGTGTCATATGTCCAAGCTTATGCAAAGCATGAATGCAACCTGATTTTCAGATTAAAGGATCTTGATTTTGCCAGCCTTGCTCGAGGTTTTGCCCTGCTGAGGATGCCCAAGATGCCAGAATTGAGAGGAAAGCAGTTTCCAGATTTTGTGCCCGTGGACGTTAATACCGACACGATTCCATTTAAAGATAAAATCAGAGAAAAGCAGAGGCAGAAACTCCTGGAGCAACAAAGAAGAGAGAAAACAGAAAATGAAGGGAGAAGAAAATTCATAAAAAATAAAGCTTGGTCAAAGCAGAAGGCCAaaaaagaaaagaagaaaaaaatgaatgagaaaaggaaaagggaagagGGTTCTGATATTGAAGATGAGGACATGGAAGAACTTCTTAATGACACAAGACTCTTGAAAAAACTTAAGAAAGGCAAAATAACTGAAGAAGAATTTGAGAAGGGCTTGTTGACAACTGGCAAAAGAACAATCAAGACAGTGGATTTAGGGATCTCAGATTTGGAAGATGACTGCTGATTCCAGTGCCACAGATGAACCCACAAGGACATAGCTGTTCCCTAACTTGGTGGATGGCTCCAGTTTGCTTTTAACGAAAATCACAACTTCAGGAGACATCTGAAAAGAATGATGTCTCTGAAAGCTGTCCTTTCAGATGAGGGAGAAATGAAGGATTTCACACTTCAGAATATTTTACTAAAAACATTCCAGTCTTggccgggtgcggtggctcctgcctataatcccagcactttgggaggctgaggcaggaggatcacttgagcccaggagttcaagaccagcctgggaacacagcgagaccctctcattaaaaacaacaaaacaaAACAATTCCAGTCTTGGAGTAGTCTAACAGAAGAAAATGTAAAATTATTTGAGTGTAAATAATAGATGTCAGTATTTATCATGATGGGTCACATATAGACATATGTACatattatatatatatatatatatatatatatatatatatatatatatatataAGCTCTTTTTTCTGAGGCTATTTTATAGTTATTTTTAAACATAAAGATACAGAAGTCTTCTTGACTTCTGATTTTCAAAACCATTCCTCAGTATCTTCAGGCATTTGACCTCCTGAATGTGCTTGGCCCTGGGCTTCAGTTATCCTTTGATGTCCTGCAGGGGTGGCTAATGTGCTGGGGTTTTTCTGTGTTAATAGTCACAGTATTGTTTTATTGGTGAATAGCTGAAAAACAGAGGGATTAAGTCATATTCCGGGAAAGAGAATTATAGTTTTTATGCCTCCTGTTGAATAAATGGTGTCCTGATTGCCTGGG

Publications

PMID - Link Title
No publications available for this retrocopy