Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FAM32EP
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:126458508-126458779  UCSC
Coordinates (T2T) chr12:126466995-126467266  UCSC
Coordinates (hg19) chr12:126943054-126943325  UCSC
Strand -
Parental Sequence NM_014077.4
Parental seq. overlap 225 bp
Parental seq. overlap (%) 15.4%
Genomic Region Intergenic
Retrocopy Summary FAM32EP, located on chr12:126458508-126458779, is a retrocopy of the parental gene FAM32A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FAM32A
Full Name family with sequence similarity 32 member A
Also known as OTAG-12|OTAG12
Coordinate chr19:16185184-16192046
Strand +
Gene summary Enables RNA binding activity. Predicted to be involved in apoptotic process. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM32AP2
Bonobo Pan paniscus FAM32AP2
Gorilla Gorilla gorilla FAM32AP2
Orangutan Pongo abelii FAM32AP2
Gibbon Nomascus leucogenys FAM32AP3
Crab-eating macaque Macaca fascicularis FAM32AP4
Rhesus Macaca mulatta FAM32AP4
Baboon Papio anubis FAM32AP2
Golden snub-nosed monkey Rhinopithecus roxellana FAM32AP2
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FAM32EP
GAGCAGGTCCAAAAAGGACCCCTGAAGCTTAAAAGCATTGCAGAGCTCAGCATAACCAAGCAGAATAAGAAAAAGAAAGACCAAGACAAGGTGAAACTCAAGGAAGTGATGGAATGAGCAAAAAGATTAAGGAGCAGAAGCAGTGTGGCCAGGACAAGTGGATCCCAGCCCAGGTGGCCTTCAAGAATCTCCAGGAGAACAAATAGAGAGGATCCTGAAGAAAGCATCCAAAACTTACAGGCAGAGTGTGGAGGACTTCAGCAGACACCTGC
>NM_014077.4
GGCACTCCAGCTACCGAAGCACTGGAGAGTGTCATGGAGGCCTACGAGCAGGTCCAAAAGGGACCCCTGAAGCTGAAAGGCGTCGCAGAGCTGGGAGTGACCAAGCGgaagaagaaaaagaaggacaaagacaaagcgaaactcctggaagcaatgggaacgagcaaaaagaacgaggaggagaaGCGGCGCGGCCTGGACAAGCGGACCCCGGCCCAGGCGGCCTTCGAGAAAATGCAGGAGAAGCGGCAAATGGAAAGGATCCTAAAGAAGGCATCCAAAACCCACAAGCAGAGAGTGGAGGACTTCAACAGACACCTGGACACACTCACGGAGCATTACGACATTCCCAAAGTCAGCTGGACGAAGTAGCCGCCTGCCCCCAGTATGGAGCAGCATCGAGGGTTCGCAAAAGGCCACACTGGGGTTGTGTGTGTTTCCTTTGGTATATTCTGGAAACATGGCTACACACACCCTTGCATCTTCTGCTACAGACTGCTTTTCGAAGCTGTGTACCCTCATTCTGGAACTTGATTAAAGTAAGATCGTCCTTGTACTCAGTTTAGGCTTCTTGGCAACATACAGAAGATACACCCTTTTCGTTTGGATGGAAAGTTTCTAAGTTTATCCAGAGGTAAAGCCCATTGTGTGTCTGTGTCATGTAAAAATGTTTTCACCCGAGTTGCATGTAACGCTCTGAGGCCAGCCAGCTGTCTTCTCCTGGATGAGACAGACTCCAGAGGGTAAGGAGCTAGCGCCATGGTGGCCTGCAGTATGCAGAGCCCCGCAGGACCCAGCGTGGGCGCCCTTCCAAGCTTCCTCTAGCTTTGGGCCTATGCTGTCCCCTGCAGGCCCTAGGGAAGCCACTTGCAACTATGCGGCCTTCAGACTTCCTCCTCAGCCACCTGGCCACTGAGACAGCATAGCCTGGGTAACGGAACAGCCACCTAAGGCAAGAATGGAACGGACACACCTTGCTCCTTTCTGAGCCCGTTTCCCAAAACCCCCCTTCCAGGTGCTTCTAATGGGTGTTGCCATAGCAGACGCTGCTAATGCATCACAGCATTCTTTGAAATGGAACCAGACACAGCCTGCCTCTCAATCCTCAGCTGGGGGCTCCTAGCAGCCTCTTGTATTTACTCAGAGTTGACACATCACACAGATCCTGTTTGGCATTCCTACCTTACGGACGTCTCAGGGGTGACAGGACCAGGGCAGAGCCCCGGTACAAACAGACAAGGCTGCAGTCAAATGGGAGGGTCCAGGTGTCCGTGTTGGAGGGCTGGGATCTTGTAGGGCCTGTGCGTCCTGGCTGAGGATCAAACCACATATGTTATTGGGAGAAACGATTTCTGTTGACGTAGATATTGAAAGAATAATGAAGGCAGAAGAGAAAAACGAAGTGTGGAATTTGGGGTTGTCCTGTGTAAATTACACAATAAAGCAAAAGTCAGTTATTGTAA

Publications

PMID - Link Title