Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NLRP9P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:129013329-129017161  UCSC
Coordinates (T2T) chr12:129044665-129048498  UCSC
Coordinates (hg19) chr12:129497874-129501706  UCSC
Strand +
Parental Sequence NM_176820.4
Parental seq. overlap 3037 bp
Parental seq. overlap (%) 85.3%
Genomic Region Intergenic
Retrocopy Summary NLRP9P1, located on chr12:129013329-129017161, is a retrocopy of the parental gene NLRP9. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NLRP9
Full Name NLR family pyrin domain containing 9
Also known as CLR19.1|NALP9|NOD6|PAN12
Coordinate chr19:55708438-55738402
Strand -
Gene summary The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NLRP9P1
Bonobo Pan paniscus NLRP9P1
Orangutan Pongo abelii NLRP9P1
Crab-eating macaque Macaca fascicularis LOC102117157P1
Rhesus Macaca mulatta NLRP9P1
Golden snub-nosed monkey Rhinopithecus roxellana NLRP9P1
Marmoset Callithrix jacchus LOC118151027P2
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Baboon Papio anubis Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NLRP9P1
GTCAGATTTTGGCTTGTTTTGGTAGCTGAAGCAGCTCAGAAACGAAGAGTTTTTGGAGATTTAAGGAGCTCCTCAAATAAGAACCTTTGAAATTGGAACTCAAGTGAATCACCTGGACTGAGCTTCCAAAGAAGATGTAGCAAAGCTGTTGGACAAACATTATCCATGAAAACAGGCATGGGAGGTGACACTGAACCTATTTCTTCAGATCAATAGGAAAGATCTCTGGATGAAGCCTCAGGAAGAGATAAGAAATAAGCTAAACCCATATAGAAAGCATATGAAAGAAAAATTTCAACTTGTATGGGAAAAGGAAACCTGTCTTCATGTCCCTGAGCATTTCTACAAAGAAACCATGAAAAATGAGTCAAAGTATTGAATGATGCATATACTGCTGAGGCTAGACTATTCACTGTGGTCCTGGAGGGTTCTGATGAAATTGGAAAAACAGCCCTTTTAAGAAAAGTGATGaaaaaaaGTGATGTTGGACTGGGCAGAGGGAAACTTATGGAAGGATAGATTTACATTTGTTTTTTTCCTTAATGTCTATGAAACGAACGGTATCACAGAGACCAGCTTACTGGAGCTCCTCTCTAGGGACTGGCCTGAGTCTCCAGAGAACATCAAAGACATTTTTTTCCCCAGCCAGAGCAAATTCTGTTCATCATGGATGGCTTTGAGCAACTGAAGTTTGACTTGGAACTTAAGGCTGACTTGTGTGATGACTGGAGGCAGCAGCAGCCAACACAAATTATCCTGAGCAGTTTGTTGCAAAAAAAGATGATTCCAGAATCCTCTCTGCTTATTGCATTAGGAAAAGTGGGTATGCAAAAAAACTATTTTATGTTGTAGCATCCAAAACTCATAAAGCTCCCAGGATTCACTGAACTTGAAAGGAAGCTGTATTTCTCCTACTTCTTCAGCGAGAAGAATAAAGCCTTGAAGGCCTTCCATTTTGTGAGAGATACTGGACAGCGGTTTATCTTGTGCCATAATCCCTTTATATGCTGGTTGGTCTGTACTTGTATGAAATGGCAGCTAGAAAGGGGAGAAGACCTTGAAATAAACTCCCAAAACACCTTCATTCATTTGTTAAAAATGAATGCATCATTTTTAACAAATGTATTTAAAGCAGGAAGTCAGAGTTTTCCACCTAAGGTGAACAGAGCCCGACTAAAAAGCCTGTGTGCTTTGGCTGCAGAGGGAATTTGGACACATGCATTTGTATTTTGCCATGGGATCTCTGGAGGAATGGGTTATCTGAGTCTGAGGGCTTAATGTGGGTGGGTATGAAACTTCTCCAAAGGTGAGGTGAGTGTTTTACCTTCATCCATGTATGTATCCAAGAGTTTTGTGCCACCATGTTTTATTTGCTCAAACGACCCAAAGATGATCCTAACCCAACCATTGGAAGCATAACCCAGCTTGTAAGAGCAAGTGTGGCTCAGCCTCAAACCCACTCGACCCAGGTGGGGGTATTCGTGTTTGGAATTTCAACAGAAGAAATCATCAGCTTGCTGGAGACATCCTTTGGTTTTCCACTGTTAAAAGACCTAAAGAAGGAAATAACCCAGTGCCTTAAAAGTTTAAGTCAATGAGAAGCTGATAGGGAAGTGATAGGTTTCCAGGAATTATTCCATGATTTATTTGCAACTCAGGAAAAAGAATTTGTAACAGAAGTGATAAATTTCTTTGAAGAAGTTTTCATTTGTACTGGTAACATAGAACATTTGGTAGTATCTTCATTCTGCCGGAAGCATTGTCAAAATTTAACTACACTTCGCATGTGTGTAGAGAATATTTTCCAGATTTCTCAGGATGCATCTCAGATCACAATGCGAAGCTCATCTACTGGCGGGAGCTTTGCTTAATGTTCAGTACCAACAAGAACTTCCAGATGATAGACATGGAAAACAGTAGCCTCGGTGATGCCTCCCTGGCAATTCTTGGCAAAGCGCTGGCTCAGCCTGTTGTAAGCCCCAAAAACCCAAATTTACTTTTATGTCTAACTTTGGAAATGATTCAGAATTATTTAAGGCAGTTCTTCACGACCCTCATCTGAAACTTCTGAGCCTGTATGGCACTAGCCTCTCCCATACTGATGTCAGCCACCTGTGTGAGACATTGAAGCACACAACATGCAAGATAGAAGAGCTGATGCTGGGAACATGTGACATCTCCGATGAAGGTTGTGAAGACATCGCCTCTGTCCTGGCCTGCAACAGCAAGCTGATACATCTCTCCTTGGTAGAAAATCCCGAAAAGGACAAAAGAATGATGTTGCTGTGCCCTGGAGACGCTGATGTTGATGTACTGCTGTCTCATCTGTGTCTCCTGTGAAGACATTTCCCACGTCCTTTTCTGCAGTAAATCCCTGTCCCTCCTTGACCTGGGGTCAAATTTCCTGGAAGATAATGAAGTGGCATCTCTGTGTGAAGCACTGAAGCACTAAGACTGAAACATACAGGAGTTGTTGTTGATGGACTGTTTCCTTACTTCCGTTTCCTATAGGGACATTGCTGCTGTTCTTATTTGCAATGAAACACTGAAGACCCTGAAACTTGGGCATGATGAAATACGAGGCGCTGGTGTCAAACAGTTATGTGATGCTTTGAAGCACCCTCACTGTAGATGAGAGTGTCTTGCACTGCAAACATAGCCGATCACCCGTGCCTGCTGTGAAGACCTTGCTGTGGCACTCACTGCCTGCAAAACATGGAGGAGCCTGAACTTCGACTGGGTTGGTTACCTTGGATGCTGATGTGGTGGTGGTGCTGTGTGAGGCTTTGAGCCACCCGGACTGTGCACTGTGGATGCTTGGTGTCACTGTAGCTGAAAGGAAtTTGATGAAAAAAAAAAAAAAAACTCAGAAGAGGCTGATGTCTGTGGAAGAAAAAATTCCCCACCTGACCAATTCACACGAACCTTGGACCAATGAGGAATACAAGATCAGGGGTGTGCTCCTCTGATGGGGAGCACCCTGAAGTAGTCTTCTCACAAAGGCTTTCCTTGGTCACAATGGGCTCTTCTCCTCCTGGCACCTCTGTCCTGTAATTGCACGTCATGGCAGCAGGTCTGTGATTTCAGGGCTACTCCCTGACGGTGTTCTAGCAATATGATTATAGAGAGTGATTCAGTGTGTATGTGCTGGCTGTCTTTGCCTCGGTTCTTTATTCCCTTATCTTTAGAAATCCCATCCTACCTTGCAATATTTGGAAGAACAAGTACATTAAATTAGTGCTAAATGCTCTGGAAAGCTTGGCTTTATTTTTTTAATGGATGTCTTGGTGTGTATGAGCATGCATTTGCAGGCATCGCAATTCTCTGATACTTCTGACGTAGAAGTGATGATAGAATGAATGTGTCTATAGTTTGTATTGCTAGCACCCAAACTTTCTGTTTCCAGTTTGTCCAGATTTAGATTTGATCAGTTTTCTTGTCCAATTAAAAAAAGCATTCCCAAA
>NM_176820.4
ACACCTCAGTTCACAATCCTGGGGCGATATGGCAGAATCTTTTTTTTCGGATTTTGGCTTGTTGTGGTATCTGAAGGAGCTCAGAAAGGAAGAGTTTTGGAAATTTAAGGAGCTCCTCAAACAACCTTTGGAGAAATTTGAACTCAAGCCAATCCCCTGGGCTGAGCTGAAGAAGGCCTCCAAAGAAGATGTAGCAAAGCTGCTGGACAAACATTACCCAGGAAAGCAGGCATGGGAGGTAACACTGAACCTGTTTCTACAGATCAATAGGAAAGATCTCTGGACAAAGGCTCAGGAAGAGATGAGAAATAAGCTAAACCCATACAGAAAGCATATGAAGGAAACATTTCAACTCATATGGGAGAAGGAAACCTGTCTTCACGTCCCTGAGCATTTCTACAAAGAAACCATGAAAAATGAGTATAAAGAATTGAATGACGCATATACTGCTGCGGCTAGACGACACACTGTGGTCCTGGAAGGTCCTGATGGAATTGGAAAAACAACCCTTTTAAGAAAAGTGATGTTGGACTGGGCAGAGGGAAACTTATGGAAGGACAGGTTCACATTTGTGTTTTTCCTCAATGTCTGTGAAATGAACGGTATCGCAGAGACCAGCTTACTGGAGCTCCTCTCTAGGGACTGGCCGGAGTCTTCAGAGAAGATCGAAGACATTTTTTCCCAGCCAGAGAGAATTCTGTTCATCATGGATGGCTTTGAGCAACTGAAGTTTAACTTACAACTTAAGGCTGACTTGAGCGATGATTGGAGGCAGCGGCAGCCAATGCCAATTATCCTGAGCAGTTTGTTGCAAAAAAAGATGCTTCCAGAATCCTCTCTCCTTATTGCATTAGGAAAACTGGCTATGCAAAAACACTATTTTATGTTGCGGCATCCAAAACTCATAAAGCTCTTAGGATTCAGTGAATCTGAAAAGAAGTCGTATTTCTCCTACTTCTTTGGTGAGAAGAGCAAAGCCCTGAAAGTCTTCAATTTTGTGAGAGATAATGGGCCGCTGTTTATCTTGTGCCATAATCCCTTTACGTGCTGGTTGGTCTGTACTTGTGTGAAACAGAGGCTAGAGAGGGGAGAAGACCTTGAAATAAACTCCCAAAACACCACCTATTTATATGCATCCTTTTTAACAACTGTATTCAAAGCAGGAAGTCAGAGTTTTCCACCTAAGGTGAACAGAGCCCGACTAAAAAGCCTGTGTGCTTTGGCTGCAGAGGGAATTTGGACATATACATTTGTATTTTCCCATGGGGATCTCCGGAGGAATGGGTTATCTGAGTCTGAGGGCGTGATGTGGGTGGGTATGAGACTCCTCCAAAGGAGAGGGGACTGTTTTGCCTTCATGCATCTGTGTATCCAAGAGTTTTGTGCCGCCATGTTTTATTTGCTCAAACGACCCAAAGACGATCCTAACCCGGCCATTGGAAGCATAACCCAGCTTGTAAGAGCAAGTGTGGTTCAGCCTCAAACCCTCTTGACCCAGGTGGGGATATTCATGTTTGGAATTTCAACAGAAGAAATCGTCAGCATGCTGGAGACCTCCTTTGGTTTTCCACTGTCAAAAGACCTAAAGCAGGAAATAACCCAATGCCTTGAAAGTTTAAGTCAATGTGAAGCTGATAGGGAAGCCATAGCTTTCCAGGAACTATTCATTGGTTTGTTTGAAACTCAGGAAAAAGAATTTGTAACCAAAGTGATGAATTTCTTTGAAGAAGTTTTCATTTATATTGGTAACATAGAACATTTGGTAATAGCTTCATTCTGCCTGAAGCATTGTCAACATTTAACGACACTTCGCATGTGTGTGGAGAATATCTTTCCAGATGACTCAGGATGCATCTCAGATTACAATGAGAAGCTCGTCTACTGGCGGGAGCTTTGCTCAATGTTCATTACCAACAAGAACTTCCAGATTTTAGACATGGAAAATACCAGCCTCGATGATCCCTCCCTGGCGATTCTTTGCAAAGCGCTGGCTCAGCCTGTTTGTAAACTCCGAAAACTCATATTTACTTCTGTGTACTTTGGACATGATTCAGAATTATTTAAGGCAGTTCTTCACAACCCTCATCTGAAACTTCTGAGCCTGTACGGCACTAGCCTCTCCCAGTCTGACATCAGACACCTGTGTGAGACGCTGAAACATCCAATGTGCAAGATAGAAGAGCTGATACTGGGAAAGTGTGACATCTCCAGTGAAGTTTGTGAAGACATCGCCTCCGTCCTGGCCTGCAACAGCAAGCTGAAACACCTCTCCTTGGTAGAAAATCCCTTGAGGGACGAAGGAATGACGTTGCTGTGTGAAGCCCTGAAGCACTCACACTGTGCCCTGGAGAGGCTGATGTTGATGTACTGCTGTCTCACCTCTGTCTCCTGTGACTCCATTTCCGAAGTCCTCTTGTGCAGTAAGTCCCTGTCCCTCCTCGATCTGGGCTCAAATGCCCTGGAAGATAATGGAGTGGCATCTCTGTGTGCAGCGCTGAAGCACCCAGGCTGCAGCATACGGGAGCTGTGGTTGATGGGCTGTTTCCTTACTTCCGATTCCTGTAAGGACATTGCTGCTGTTCTTATTTGCAATGGGAAACTGAAGACCCTGAAACTTGGGCATAATGAAATAGGAGACACTGGTGTCAGACAGTTATGTGCAGCTTTGCAGCATCCTCACTGTAAATTAGAGTGTCTCGGGCTGCAAACGTGTCCGATCACCCGTGCCTGCTGCGACGACATCGCCGCAGCACTCATCGCCTGCAAAACACTGAGGAGCCTGAACCTCGACTGGATTGCCTTGGATGCTGATGCAGTGGTGGTGCTGTGTGAGGCATTGAGCCACCCGGACTGTGCCCTGCAGATGCTGGGGCTGCACAAATCTGGCTTTGATGAAGAAACTCAGAAGATCCTGATGTCTGTGGAAGAAAAAATTCCCCATCTGACCATTTCACATGGACCTTGGATTGACGAGGAATACAAGATCAGGGGTGTGCTCCTCTGATGGGGAACACCCTGAAGTAGTCGTCTCACAAAGGCTTTCCTTGGCCACAGTGGGACCTTCACCTGGCACCTCTATCCTGTAATTGCACATCATGGCAGCAGGGCTGTGATTTCAGAGGTACTCCCTAAGTGTTCTAGCAATATGATTATGGAGTGTGATTCAGTGTACATGCTGATTGTCTTTGCCTCGGTCCTATATCCCCTTGTCTTTAGAAATCCCATCCTGCCTTGTGATATTTAGAAGCACAAGTACGTTAAACAAGTGCTAAACGCTCTGGAAAGCATGGCTTTATTTTCTTAATGGATGTCTTGGTGTGTAGGAGCATGCATTTGTAGGCACCACAATCCGGATACTTCTGACACAGAAGTGATGCTAGAATGTGTCTATAGATTGTATTGCTAGCATCCAGACTTTCTAGTTTGTCCAGATTTCGATTTGATCAATTTTCTTGTCCAATAAAAAAGCATTTCCAAA

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