Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HTR7P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:13001218-13004787  UCSC
Coordinates (T2T) chr12:12874925-12878493  UCSC
Coordinates (hg19) chr12:13154152-13157721  UCSC
Strand +
Parental Sequence NM_000872.5
Parental seq. overlap 2911 bp
Parental seq. overlap (%) 85%
Genomic Region Intergenic
Retrocopy Summary HTR7P1, located on chr12:13001218-13004787, is a retrocopy of the parental gene HTR7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HTR7
Full Name 5-hydroxytryptamine receptor 7
Also known as 5-HT7
Coordinate chr10:90738693-90858039
Strand -
Gene summary The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HTR7P1
Bonobo Pan paniscus HTR7P1
Gorilla Gorilla gorilla HTR7P1
Orangutan Pongo abelii HTR7P1
Gibbon Nomascus leucogenys HTR7P1
Green monkey Chlorocebus sabaeus HTR7P1
Crab-eating macaque Macaca fascicularis HTR7P1
Rhesus Macaca mulatta HTR7P1
Baboon Papio anubis HTR7P1
Golden snub-nosed monkey Rhinopithecus roxellana HTR7P1
Marmoset Callithrix jacchus HTR7P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HTR7P1
CCCGCGCGTCCCGGGCGTCCGTCGGGGTCCGAGGTCCCTCCCTCAGGGAGTCCCCGCTCGGCAGCGCTCTCGCGTTTCACGCAGCGGCCGGGGATCTGGGACAGGCGGGGCCCCGAGGCCGAGCCTGGCGCTGCCCAGCGGCCGGTGCAGGCCTCAAGCTGGGCCGGGCGGAGGGGAACCGGCGAGTTGAAGCCCCGGGGCCGAAAGCCGGAGCCTGTGGCGGCCGCGGGGGTGGGGAGGGGGGTGGGGCGGCTTCTTGGGCAGCGCCACACGGCGGCGCAGTGATGGATGTTAACAGCAGCGGCCACCCGGACCTCTACGGGCGCCTCTGCTCTTTCCTCCTGCCGGAGGTGGGGGGCAGGCTGCCCGACCTGAGCCCCGACGGTGGCGCCGAACCGGTCGCGGTCTCCGGGACGCCGCATCTGCTGAGCGGGGGCCCCCGAGGTGACGGCCAGCCCGGCGCCCACCTGGGACGCAACCCCGGGCAATGCCTCCGGCCGCGGGGAGCAAATCAAGAAAGGGCCGAGAAAGTTGTGATCGGCTCTGTCCTGACGCTCATCTCTCTGCGATCGCGGGCAACTGCCTGGTGGTATCTCCGTGTGCTTCGTCAAGAAGCTCCGCCAGCCCTCCAACTACCTGATCGTGTCCATGGCGCTGGCCAACCTCTCGGTGGCCATGGCGGTCATGCCCTTCATCAGTGTCACCGACCTCATCGGGGGCAAGTGGATCTTTGGACACTTTTTCTGTAACGTCTTCTCCATGAATGTCATGTGCTGCACGGCCTGGATCTTGACCTTGTACGTGATCAGCATCGACAGGTACCTTGGGATCATGAAGCCTCTCACGTACCCTATGAGGCAGAAGGGGAAATGCATGACGAAGATGATTCTTTCTGTCTGCCTTCTTTCCGCCTTTGTCACTTTACCTACCATTTTTGGTCGGGCTCAGAATGTAAACGATGATAAGGTGTGCTTGGTCAGTCAAGACTTTGGCTACACGATTTACTCCACCGCAGTGGCATCCTAATCCCCATGTGCGTCATGCTTTTCATGTACTAACAGATTTACAAGGCCGCCAGGAAAAGCGCGGCCTAACACAGGTTACCTGGCTTCCCTCGAGTGGAGCCAGACAGCAGTAGTCACCCTGAATGGCACAGTGAAGTTCCAGGAGGTGGAAGAGTGTGCAAACCTTTCGAGACTCCTCAAGCATGAAAGGAAAAAATATCTCCATCTTTAAGCGGAAACAGAAAGCAGCGACTACCTTGGGGATCATCGTCTGGGCCTCCACCATGTGCTGGCCGCCCTTTTTCCTCCTGACAGCCAGACCCTTCTGTCTATGGCACTGCCTGCAGCTGCATCCCACTGTGGGTGGAGAGGATATTTCCATGGCTGGGCTATGCAAACTCTCTCATTAACCCTTTTATTTATGCCTTCTTCAACTGGGACCTGAGGACCACCTATTGCAGCCGGCTCCAGTGCCAGTACCAGAATATCAACCAGACACTCTCAGCTGCAGGCATGCATGAAGCCCTGAAGCTTGCTGAGAGGCCAGAGAGACCTGAGTTTGTCCTACAAAACTCTGACTACTGTAGAAAAAAAAGTCATGATTCATGACTGAAAGAGGGATAATGGAGATGAAATAAACAAGGCAAAATAGAGGTGGAAACAGAAGAAAGTCATTTGCCAAGACTGCAGAATGGAATGCAGCTTCTGTCCTTTCTTAGGATGGCTAAAACGTGACAAACAGCATGACCTGATGTACAACATATCTTATGAGGGAGATGGTGACCTCTCCTTTTTTCTGTGGATCAGTGTTATTGTGTGTTCTCAGTTTAAGATAGCAGATCATCTCAGCAGTAAGCACACTGACAGAATTGAGTTCCAGAAAGGAAGCAGTTTCAGGTTCTTAGCACATGTCCAAATCCATGCAAGTGGGAGAAAGTTCCAATGCACACTTTCCATGCTTCCGAGTCTAGGTCTCGTGGTGAATATTCAGCAATCATTCATGAGAAAGAATGTATTTTGTTGTATGACAGAAGGGTTTACCAAGCAAACTGTGGTAAGCATAGTATCGAATATGTTGCATGTCCATTTTAGAAAACAGAGCCCAGTCATCAGCTAATACAAATGATTTCCCAGAGCAGTGTTTGTTTCAAGCTTCTGTCAAATAGTTTGGCTTTTCTGCAGGGTCCCTGTAACTTCCCCACAAATGTACTTCTTTGTTAATTCACTTATTGTTATGGTGTGGCTCAGGAACAGGTCTCAGGATGGAGAGCAGCATACAACCTGAACAAAGCTTTTTCTTGTGCTCTGAAGGGTCCTGAGACGTGAGGGGGATGCCTTCCATGAGGATTTTTATCTCAGTGAAGTGCGAGTGGTACCCACCTGTATTGTCATTAACATGATTATTGGCATGTTTTTGACTCTCATTTTTCACAAGGGTGCAGTGGGGCCATGGACCATCCCATGGGATGGTCCATAACTGTATGTTATATGGAAATAGTGTGGGAATAATGGGTTTTCCATGAAAGGTTGTGATGCTTCTGGAGATGGGGGCATAAACGTGTTCATTCTTGTTGAGCAGCATTGTGTTAAACCAAATTGTGTGAAGTGGAGGTCACCTGGACCACTCCTGGGAAATGCTCCAGAACACCAGTCTGTTCCTTCTAGAAATTTGTTCTCTGTAcTGTTCTCTGTATCTTAAATCAACTCTGTGCCAAAGCAGTTCTGTCCCCTGACTCCCACCCCTACCCACCAAAAAGTGGTAGACATGAAGGGCAGGTAAGGGAACAGAAAATGTCTCCTTGCAGCTATATATATTTTAAACGAACTGTGTAATAAGTATGAGCTAAGGAGACAGAAAGACAGTAGATGAGAAAAGAAGAGTACCTATACCTACAAGGGGCAAAATGAATGCAATCCTTCATTTGATAAGAGAGAACTGAAAGAGAATATTATTTTTCTACAATAAAGCAAGCTGTCCTCTCAGGATAAAGTGGAATTTCGACATGGATTATGGACTTCTTCCAACTCCCATTGACATTGCTTCTTACCACACATGGGGAAGGGCTGCCTTTCCTGAAAGGGGAAGAAGGCACTGTCCTTTCAGACAAAGTTTGTACAAATTCCTGAACTGCAGATTTGCTAATGTGACCGCGTATACTTATATTCATAATTTAAGTGATTGTTTATGGTCAGATACATATTGTTAAACTTGAAAATGTTTTATTACATTACATCAAATAAAGTCTATTTGTAGCTGAAA
>NM_000872.5
GCACTCCGCAACTTCTGCCGCTGCCGCCCGGGCGCTCTCGGCGCAGCCGAGCTGCTGCTGCGAACTGTGGAGCTGCCAGCGGAGCCCAGCCCGAGCTCCCTCGACTCCGCGCGTCCCAGGCGTCCGTCGGGGGCCGAAGCGCCTCCCGCAGGGAGTCCCCGTGAGGCCGCGCTGCCGCGTTACCCGCAGCGGCCGGGGGTCCGGGGAGTGCGGGGCTCCGAGACAGAGCCAGGCGCCCCCCAGCGGTCGGCGCGGGCCCCATGGCTGGGCCGGGCGGAGCGGAACCGGTGAGGTGAAGCCCCGGGGCCGGCAGCCGGAGGCGCGTGGCCGGGGCGCCGGCTCCATGGGCAGCGGCACACGGCGGCGCGATGATGGACGTTAACAGCAGCGGCCGCCCGGACCTCTACGGGCACCTCCGCTCTTTCCTTCTGCCAGAAGTGGGGCGCGGGCTGCCCGACTTGAGCCCCGACGGTGGCGCCGACCCGGTCGCGGGCTCCTGGGCGCCGCACCTGCTGAGCGAGGTGACAGCCAGCCCGGCGCCCACCTGGGACGCGCCCCCGGACAATGCCTCCGGCTGTGGGGAACAGATCAACTACGGCAGAGTCGAGAAAGTTGTGATCGGCTCCATCCTGACGCTCATCACGCTGCTGACGATCGCGGGCAACTGCCTGGTGGTGATCTCCGTGTGCTTCGTCAAGAAGCTCCGCCAGCCCTCCAACTACCTGATCGTGTCCCTGGCGCTGGCCGACCTCTCGGTGGCTGTGGCGGTCATGCCCTTCGTCAGCGTCACCGACCTCATCGGGGGCAAGTGGATCTTTGGACACTTTTTCTGTAATGTCTTCATCGCCATGGACGTCATGTGCTGCACGGCCTCGATCATGACCCTGTGCGTGATCAGCATTGACAGGTACCTTGGGATCACAAGGCCCCTCACATACCCTGTGAGGCAGAATGGGAAATGCATGGCGAAGATGATTCTCTCCGTCTGGCTTCTCTCCGCCTCCATCACCTTACCTCCACTCTTTGGATGGGCTCAGAATGTAAATGATGATAAGGTGTGCTTGATCAGCCAGGACTTTGGCTATACGATTTACTCTACCGCAGTGGCATTTTATATCCCCATGTCCGTCATGCTTTTCATGTACTACCAGATTTACAAGGCTGCCAGGAAGAGTGCTGCCAAACACAAGTTTCCTGGCTTCCCTCGAGTGGAGCCAGACAGCGTCATCGCCCTGAATGGCATAGTGAAGCTCCAGAAGGAGGTGGAAGAGTGTGCAAACCTTTCGAGACTCCTCAAGCATGAAAGGAAAAACATCTCCATCTTTAAGCGAGAACAGAAAGCAGCCACCACCCTGGGGATCATCGTCGGGGCCTTTACCGTGTGCTGGCTGCCATTTTTCCTCCTCTCGACAGCCAGACCCTTCATCTGTGGCACTTCCTGCAGCTGCATCCCACTGTGGGTGGAGAGGACATTTCTGTGGCTAGGCTATGCAAACTCTCTCATTAACCCTTTTATATATGCCTTCTTCAACCGGGACCTGAGGACCACCTATCGCAGCCTGCTCCAGTGCCAGTACCGGAATATCAACCGGAAGCTCTCAGCTGCAGGCATGCATGAAGCCCTGAAGCTTGCTGAGAGGCCAGAGAGACCTGAGTTTGTGCTACAAAATGCTGACTACTGTAGAAAAAAAGGTCATGATTCATGATTGAAAGCAGAACAATGGAGATGAAATAAACAAGGCAAAATAGAGGTGGAAACAGAAGGAAGTCATTTGCTGAGTCTGCAGAATGGAATGCAGCTTCTGTCCTTTCTTGGGATGTCTAAAACATGACAAACAGGGTGATCTGTTGTACACACTATCTTATGAGGGAGATGGTGACTTCTCCTTTTTTCTGTGGATCAGTGCTATTGTGTGTTCTCAGTTTAAGATAGCAGATCATCTCAGCAGTAAGCACACCAACAGAACTGAGTTCCAGAAAGGAAGCAGTTTCTGGTGCTTTGCATATGTCCAAATCCATGCAAGTGGGAGAAAGTTCCAGTGCACACTTCCCATGCTTCTGAGTCTAGGCGTTGTGGTGAATATGCAGGAATCATTCATGAGACAGAATGTATTTTGTTGTATGACAGAAGGCTTTTCCAAGCAAACTGCGGTGAGCGTAGTGTTGAATATGTTGCATGTCCATGTTAGAAAACAGAATCCAGTCATCAGCTAATACAAATGATTTCCCAGAGCAGTGTTTGTTTCAAGCTTCTGTCAAATAGTTTGGCTTTTCTGCAGGGTCTCTGTGATTTCCCCACCTATGTACTTTTCTGTGTTAACTCACTTATTATGGTATAACTCAGGAACAGGTCTCAGGATGGAGAGAAGCATACAACATGAGCAAAGCTTTTTCTCGTGCTCTGAAGGGTCTTGAGAGGGGAGTGGGATGCCTTCTGTGAGGATTTTTATCGCAGTGAAGCTCAAGTGGTACCCAACTGCGTTGTAATTAACATGATTATTGGCATGTTTTTGACTCTCATTTTCTACAAGGCTGCAGTGGGCCCACCCATGGGCTGGCCCATAACTGTATGTTATGTGGAAGAAGTGTGGGAATGATGGGTTTTCCATGAAATGTGATGCTTCTGGAGATGGGGCATAAACATGTTCATTCTTGTTGAGCTGCATTGTGTTAAACCAAATTGTGTGAAGCGAGGTCACCTGGACCACTCTTGGGAAATGCTTCAGAACACCAGTCTGTTCCTTCTAGAGAATTTGTTTTTGTGTTCTATGTATCTTAAATCAAATGTGTGCCTAAGCAATTCTGTCCTCTGATTCCCACCCCTACCCACCAAAAAATGGTAGACATGAAAGGCAGGTGAGGAAACAGAAAAGGTCTCTTTGCAGATATATATTTTTTAAATGGCACTATGTAGTAATTAAGAGCTAAGGAGACAGAAAGACAGTAGATGAGAATAGAAGAGTACCTGTACCTACAAGGGGAAAAATGAATGCAATTCTTTATTTGATAAGAGTGAACTGAAAGAGAATATTATTTTCCTACAATAAAGCAAGCTGTCCTCTCACAGGATAAAGTGGAATTCTGACATGGATTATGGACTTCTTCTAACTCCCATTGACATTGCTTCTTACCAGACATGGGGAAAAGCTACCTTTCCTGAAAGGGGAGGAGGGCACTGTCCTTTCAGACAAAGCTTGTACAAATTCCTGAACCGCAAATTTGCTGAAGTGACCGTATATATTATATTCATAATTTAAATGATTATTTATGGTCAGATACATATTGTTAAACTTGAAAATGTTTTATTACATTACATCAAATAAAGTTTATTTGTAGCTGAAATAAAGCAACGTAAGTAACAATTTTTAA

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