Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GNAI2P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:14254933-14255486  UCSC
Coordinates (T2T) chr12:14131791-14132344  UCSC
Coordinates (hg19) chr12:14407867-14408420  UCSC
Strand +
Parental Sequence NM_002070.4
Parental seq. overlap 512 bp
Parental seq. overlap (%) 23.1%
Genomic Region Intergenic
Retrocopy Summary GNAI2P1, located on chr12:14254933-14255486, is a retrocopy of the parental gene GNAI2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GNAI2
Full Name G protein subunit alpha i2
Also known as GIP|GNAI2B|HG1C|H_LUCA15.1|H_LUCA16.1
Coordinate chr3:50227068-50259362
Strand +
Gene summary The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes GNAI2P1
Bonobo Pan paniscus GNAI2P1
Orangutan Pongo abelii GNAI2P1
Gibbon Nomascus leucogenys GNAI2P1
Green monkey Chlorocebus sabaeus GNAI2P2
Crab-eating macaque Macaca fascicularis GNAI2P1
Rhesus Macaca mulatta GNAI2P1
Baboon Papio anubis GNAI2P1
Golden snub-nosed monkey Rhinopithecus roxellana GNAI2P1
Marmoset Callithrix jacchus GNAI2P2
Gorilla Gorilla gorilla Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GNAI2P1
GCAACAAGTGGTTCACAAACACGTCCATCATCTACTTCCTCAACAAGAAGGAGCTGTTGGAGGAGAAGATCACACACAGCCCCTGACCATCTGCTTCCCTGAGTACACAGGGTCCAACAAGTATGATGAGGCAGCCAGCTACAACCAGAGTAAGTCTGAGGACCTGAATAAGCACAAAGACACCAAGGAGATCTACACACACTTCACATGCGCCACCGATACCAAGAACGTAGTTCGTGTTTGATGCCATCACCGACGTCATCATCAAGAACAACCTGAAGGACTGGGGCCTCTTCTGAGGGGCAGTGGGACCTAGCAGGATGGGCCACCACCAACTCTGTACCCCCCAACCCCTGAGGAAGATGGGGCAAGAAGACCATGGTCCCCACCTGTTCCCTGGACACTTTTCTCTTCTTTCCTTTGTTCTTAGCTCCCCCATCCCCTCAGCTTCAGACATAGGGGAGGGGTTGCCACAGGCCTCCCTGTTTGAAGCCTGCCCTTGTCTGAGGTGCCAGTAATGGCCATGGTACCCCCTTTCTGGGCATCTTTCTGGT
>NM_002070.4
AGTCGCTCGGAACTGCCGACCCGAGTGCTTCCCGCAGAGGGCTGGTGGTGGGAGCGGAGTgggtcgggcggggccgagccgggccgtgggccgtgtgggggccgggcggcggccgggccggCGGACGGCGGGATGGGCTGCACCGTGAGCGCCGAGGACAAGGCGGCGGCCGAGCGCTCTAAGATGATCGACAAGAACCTGCGGGAGGACGGAGAGAAGGCGGCGCGGGAGGTGAAGTTGCTGCTGTTGGGTGCTGGGGAGTCAGGGAAGAGCACCATCGTCAAGCAGATGAAGATCATCCACGAGGATGGCTACTCCGAGGAGGAATGCCGGCAGTACCGGGCGGTTGTCTACAGCAACACCATCCAGTCCATCATGGCCATTGTCAAAGCCATGGGCAACCTGCAGATCGACTTTGCCGACCCCTCCAGAGCGGACGACGCCAGGCAGCTATTTGCACTGTCCTGCACCGCCGAGGAGCAAGGCGTGCTCCCTGATGACCTGTCCGGCGTCATCCGGAGGCTCTGGGCTGACCATGGTGTGCAGGCCTGCTTTGGCCGCTCAAGGGAATACCAGCTCAACGACTCAGCTGCCTACTACCTGAACGACCTGGAGCGTATTGCACAGAGTGACTACATCCCCACACAGCAAGATGTGCTACGGACCCGCGTAAAGACCACGGGGATCGTGGAGACACACTTCACCTTCAAGGACCTACACTTCAAGATGTTTGATGTGGGTGGTCAGCGGTCTGAGCGGAAGAAGTGGATCCACTGCTTTGAGGGCGTCACAGCCATCATCTTCTGCGTAGCCTTGAGCGCCTATGACTTGGTGCTAGCTGAGGACGAGGAGATGAACCGCATGCATGAGAGCATGAAGCTATTCGATAGCATCTGCAACAACAAGTGGTTCACAGACACGTCCATCATCCTCTTCCTCAACAAGAAGGACCTGTTTGAGGAGAAGATCACACACAGTCCCCTGACCATCTGCTTCCCTGAGTACACAGGGGCCAACAAATATGATGAGGCAGCCAGCTACATCCAGAGTAAGTTTGAGGACCTGAATAAGCGCAAAGACACCAAGGAGATCTACACGCACTTCACGTGCGCCACCGACACCAAGAACGTGCAGTTCGTGTTTGACGCCGTCACCGATGTCATCATCAAGAACAACCTGAAGGACTGCGGCCTCTTCTGAGGGGCAGCGGGGCCTGGCGGGATGGGCCACCGCCGACTTTGTACCCCCCAACCCCTGAGGAAGATGGGGGCAAGAAGATCACGCTCCCCGCCTGTTCCCCCGCCGCTTTTCTCCTCTTTCCTCTCTTTGTTCTCAGCTCCCCCTGTCCCCTCAGCTCCAGACGTAGGGGAGGGGTTGCCACAGGCCTCCCTGTTTGAAGCCTGCCCTTGTCTGAGATGCTGGTAATGGCCATGGTACCCCCTTCTGGGCATCTGTTCTGGTTTTTAACCATTGTCTTGTTCTGTGATGAGGGGAGGGGGGCACATGCTGAGTCTCCCAAGGCTGCGTCTGGAGGGGCCCCTGCTTCTCCAGCCTGGACCCCCAGCTTTGcccaacaccagcccctgccccagcccaagtccAAATGTTTACAGGGAGCCTCCTGCCCAGTCCCCCAACCCCAGCCGCTCGGAGGCCCCAAAGGAAAAAGCACAAGAAGCGTGAGACGCCACCATTCCTGGAAACCACAGTCCACCTGCTCATTCTCGTAGCTTTTTAAAAAAATGAAAGTAAAGGAAAAAAAAAAAACTGCAAATCTAGAAAACTTTTTAGAGAAAAACTATTTAAAACTGTCAGATCCTGACCAGCAAGCCCCCCCCCAGCCCCCCTTCCAAGTGACTCCGTGCCTTGAGTGTGTCTGCGTGTTTACACCCGTCCCTCTGCTGGCCGCCCCCGTGCGAGCGGCACCCCTGCCCTGCCCTCCACAGAATTGGGTTCCAAGGGCTGTTCCAGACAACTGCCAACGTCACTGAGGGCCCTGCCCCAGCGGCCCTGGCCCCAGGCTCTATTAACCTAAAATGTAGCTCCCTAGCGCTAACCTAGGAACCGCCGCTGCCTGCTGGGGGGCCACGCCCCTCATGCCCTTGTCCCAGGCCCGGGGCCTTCAGCGTTGAACACTTCCTTGCTTTTTTCACATGTTTTATGGAATTGTTCACCTGGTTTGAAATAATAAAATGTAGAAAGAAAAAAAATACCGAGAA

Publications

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