Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SUPT16HP1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:16398110-16402509  UCSC
Coordinates (T2T) chr12:16275532-16279931  UCSC
Coordinates (hg19) chr12:16551044-16555443  UCSC
Strand -
Parental Sequence XM_011536381.2
Parental seq. overlap 3033 bp
Parental seq. overlap (%) 55.5%
Genomic Region Intergenic
Retrocopy Summary SUPT16HP1, located on chr12:16398110-16402509, is a retrocopy of the parental gene SUPT16H. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SUPT16H
Full Name SPT16 homolog, facilitates chromatin remodeling subunit
Also known as CDC68|FACTP140|NEDDFAC|SPT16|SPT16/CDC68
Coordinate chr14:21351472-21384019
Strand -
Gene summary Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SUPT16HP1
Bonobo Pan paniscus SUPT16HP1
Gorilla Gorilla gorilla SUPT16HP1
Gibbon Nomascus leucogenys SUPT16HP1
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SUPT16HP1
TATTCATCAGAAGCAGAAGAGTCAGACTCTTCTAAGGAGTCGTTGGGTAGTGAAGAAGAGAGTGGAAAGGATTGGGATGAACTGGAGGAAGAAGCCCGAAAAGCGGACCAAGAAAGTTGTTATAAGGAAGAAGAAGAACAAAGTCGAAGTATGAGCCAGAAGAGGAAGGCATCTGTGCACAGTTTGGGCCATGGCTCTAACCGTGGTTCCAACCATGGTTCCACACACAGCTCTGCACCCCCCAAGAAAAAGAGGAAGTAACTTCTGAACTTTGGCCCTGAGCTCCTTTCTTCCTCTAGCCAAACCCTGAAAATTTTACATGACATAGAAACTGTATTTTTCCTTTTGTTTTCATTTGAAGTTTTGCCATTTGTGTTTATGGGTTTCGGGGGCCATTTATGTGGACCAATCTACTCGGAGCATTCCAGGCCCACCAGGACACGTGCCAATGGCCCCATTCAGATGGCAAGGGAGGAGGTGTTCTTGAGGACAGGAGGAGGCTCTTGCTGTTAATAAATATTGTTTCATTCTTCTTTCTTCCTGTCACCTTGTGCCAGGACATCGATGGCTTCTGACATCTTATTTGGTGTCTCAAAGCTGTATTTCCAAGACAGTGGTACAAGGTGACCCTTAATAACCCATATCATGGTTCTTGACCAGCACATTCAATCCTCCAACCTACCCTATTGCCATGACCTTCCTCACATCTCTTTAAGTTTTATCTTTGCAATACTCAAGGTTCTTGGAAATTTACTGATTGTTGTGATAAACTATACAACTTGAGCCAGTGAGGCAGATTGGGCTGGTGCCTTTGTCCGAGTTTTCCTGCTTCCTTGCCTCATGCAGATTCTGAGGTATATCTGCTGCCTTAGAAGACACAAAAAGCAATGATACTCCCTGGCTCGGTTATTTTCTCCATACAAATGCACACATGGTACAATGATAGAAGGCAAAATTGCCACTGTCTTCTTTTTTTTCTGATATATCTAAGGAAGAATGGTTGTGCCTCATGTACTGCTTCTAGTGAAATCTAGAGGAAGGCTCAAAGAAGTCAACATGTAGATCTGGAAGGGACAAGTCATGCCTTGGGCCTAGAATACCCTGAGGAGTAAAGAGAAGAGGAAGGGAGGCCATATCTACAACACAGCCTCTCAGCACTGCTGCTCCTTATTTTAACTTTGTCTTGCATTGTCCTGTATTTATCACAGTTTCTGTTGAACAGCTTTTCAAGCATTTGGGGAGTTTATCTTGCCATCCTCCCCTTTTGGTTCTCTGCACCCACCTGTCCCACTGCAGTTCCTTCCATGCTCTGTGACTTTAAGAGAAGTGGGGAGGGGTCTCGGATTTTATGTTTGTTTGTTTTTTCTCCTTAGCAGTAAGACTTGATGTTTTCAATTTTGGAAGAACTAAAAGATGAATAAACTGTCCTTTTGGGAAGAGGTTCTCGGGCAGCATTACTTACAGAAAGAACAGGAATGAAATGACTGCAGAAGAGAAGTGAAGAGCACATCAAAAAGAACTAGTGGCTCAACTCAATGAAGAAGCAAAGAGGTGACTGACTGAACAAAAGGGAGAACAGGAGATTCAGAAAGCTCACAAATCTAATGTGTCCTATAAACACCCATCTCTGATGCCTAAGGAACCACATATTGGGGAAATGAAGATCTACATCGATAAGAAATATGAGACTGTAATAATGCCTGTGTTTGGCATTGCAACACCTTTTCACATTGCCACAATCAAGAATATAAGTATGTCCGTGGAAGGAGATTATACTTACTTGCAAATCAACTTTTATTGCCCAGGCAGTGCTCTGGGCAGGAATGAAGGCAACATCTTTCCTAACCCTGAAGCGACTTTTGTCAAAGAAATTACATACCAAGCGTCATACGATGACCGGGGAACAGACAGTACCAGCCTTGAACCTTCAGAATGCTTTCCGAATTATTAAAGAAGTACAGAAACGTTATAAAACTTGAGAAGCTGAAGAGAAAGAGAAGGAGGGCATTGTAAAACAAGACTCACTGGTGATCAATCTAAACTGGAGTAATTCCAAACTGAAAGATCTATACATTCGCCCAAATATTGCCCAAAAGAGGCTGCAAGGCTCACTGGAGGCCCGTGTCAATGGCTTCCGCTTCATATCTGTTCGAGGAGACAAACTGGATATTTTGTACAATAATATTAAGCATGCTTCATTCCAGCTCTGTGATGGAGTAATGATTATTGTCTTGCATTTTCACCTCAAGAATGCCATCATGTTTGGGAAGAAGTGGCACATGGATGTGCAGTTCTACACAGAAGTGGGAGAGACAACCACGGACTTAGGGAAACATCAACATATGCATGACCGAGATGACCTCTATGCTGAGCAGATGGAACGAGAAATGAGGCACAAACTGAAAACAGCCTTTTAGAATTTCATGGAGAAAGTAGAGGCTCTAACTAAGGAGGAACTGGAATTTGAAGTGCCTTTTAGGGACTTGGGATTTAACAGAGCTCCCTACAGGAGTACCTGCCTCCTTCAGCCCACTAGTAGTGCGCTGGTAAATGCTATGGAATGGCCACCTTTTGTGGTGACATTGGATGAAGTAGAGCTGATTTACTTTGAGCGGTCCAGTTTCACCTGAAGAACTTTGATATGGTAATTGTCTACAAGGACTACAGCAAGAAAGTGACCATGATCAATGCCATTCTTGTAGCCTCTCTTGACCCATCAAGGAATGGTTGAATTCCTGCAACCTGAAGTACACAGAAGGAGTACAGTCCCTCAACTGGACTAAAGCAATAAAGACCATTGTTGATGACCCTGAGGGCTTTTTCGAACAAGGTGTCTGGTCTTTTCTGGAGCCTGACGATGAGGGGAGTGATGCTGAAGAAGGGGATTCAGAGTCTGAAATTGAAGATGAGACTTTTAATCCTTCAAGAGTGCGGGATTCCTGGGCCGAGAGCAGGTGGCAGAGCCGGGACATCGCGTGATTCTCAGAACCCGAGGAGAAGCGGCGTCCAGGGCTATGGCTGTGACTCTGGACAAAGACGCTTATTATCGGTGAGTGAAGAGACTGTACAGCAATTGGCAGAAAGGAGAAGATGAGTATGCCAACGTTGAGCCATTGTTGCATCAGTGGGTGTTGATGAAGAAATTGTTTATTCCAAATCAACTGCCTTACAGACATGGCTCTTTGGTTATGAACTAACTGATACTACCATGGTCTTTTGTGATGACAAAATCATCTTTATGGCCAGCAAAAAAAAAGTGGAGTTTTTGAAACAAATTGCCAACACTAAGGGCAATGAGAATGCTAATGGAGCCCCTGCCATCAGACTGCTGATATGAGAAAAGAATGAAAGTAGTAAGAATAGCTTTGACAAAATGATTGAAGCCATTAAAGAAAGCAAGAATGGCAAGAAGATTGGAGTGTTCAGCAAAGACAAATTCCCTGGAGAGTTCATGAAGAGCTGGAATGACTGCCTCAACAAAGAAGGCTTTGACAAAATAGATATCAGTGCAGTTGTGGCATATACAGTCGCTGTAAGGGAGGATGGGGAGCTCAAATTAATGAAGAAAGCAGCTGGCATCACTTCTGAAGTCTTCAACAAATTCTTCAAGGAAAGAGTCATGGAAATAGTTGATGCAGATGAGAAAGTTTGACACAGCAAACTGGCTGAGTCTGTGGAAAAGGCCGTTGAAGAGAAAAAATACCTTGCTGGGGCAGACCCTTCTACTGTGGAAATGTGTTACCCTCCTATCATTCAGAGTGGTGGCAACTATAATCTCAAGTTCAGTGTGGTGAGTGACAAGAATCACATGTATTTTGGGGCTATCACTTGTGCCATGGGTATTCGCTTCGAGTCTTATTGCTCCAACCTGTTCGCACTTTGATGGCTGATCCTCCTCAGGAAGTTCAAGAAAATTACAACTTTTTACTCCAGCTTCAAGAAGAGCTGCTGAAGGAATTAAGACATGGTGTGAAGATATGTGATGTATATAATGCTGTCATGGACGTGGCTAAAAAGCAGAAGCCAGAACTCCTGAACAAAATTACCAGAAACCTAGGATTTGGGGTGGGAATTGAATTCCATGAAAGCTTCCTAGTAATCAATAGTAAAAATCAATACAAACTGAAGACAGGAATGGTTTTCAGCATCAGTTTGGGATTCTCAGACCTGACTAACAAGGAGGGGAAAAAGCCAGAAGAGAAAACCTATGCCCTGTTCCTTAGTGACACAGTGCTTATGGATGAGGATGGCCCAGCTACTGTTCTCACTTCTGTGAAGAAGAAAGTGAAGAATGTGGGTATTTTCCTAAGGAACg
>XM_011536381.2
GGGAGAGTGCGGGATTCCTGGGCCGAGAGCGGGTGGCTGAGCCGGGACCTCGCGTGATTCTCGGAACCCGAGGAGAAGCGGCGTCCGGGGCTATGGCTGTGACTCTGGACAAAGACGCTTATTATCGGCGAGTGAAGAGACTGTACAGCAATTGGCGGAAAGGAGAAGATGAGTATGCCAACGTTGATGCCATTGTTGTATCAGTGGGTGTTGATGAAGAAATTGTTTATGCCAAATCAACTGCCTTACAGtcttcagggacccaggctttttccagttctctgttctgccacccaaagaacatagccctcttgcacgtggtacagaatggcttctagaactccaggtgtttcatctacattccaagcaaaaagagacagagaagaaaacaggaggccaccttttctttttaagaagacttgcttgaagctccacacactaccattttttacctattggccaaaatttgatcctaatgaccatacttacctgaaaggaagACATGGCTCTTTGGTTATGAACTAACTGATACTATCATGGTCTTTTGTGATGACAAAATCATCTTTATGGCCAGCAAGAAAAAAGTGGAGTTCTTGAAACAGATTGCCAACACTAAGGGCAATGAGAATGCTAATGGAGCCCCTGCCATCACACTGCTAATACGAGAAAAGAATGAAAGTAATAAGAGTAGCTTTGACAAAATGATTGAAGCCATTAAAGAAAGCAAGAATGGCAAGAAGATTGGAGTGTTCAGCAAAGACAAATTCCCTGGAGAGTTCATGAAGAGCTGGAATGACTGCCTCAACAAAGAAGGCTTTGACAAAATAGATATCAGTGCAGTTGTGGCATATACCATCGCTGTAAAGGAGGATGGGGAGCTCAACCTAATGAAGAAAGCAGCCAGCATCACTTCTGAAGTCTTCAACAAATTCTTCAAGGAAAGAGTCATGGAAATAGTTGATGCAGATGAGAAAGTTCGACACAGCAAACTGGCTGAGTCTGTGGAAAAGGCCATTGAAGAGAAAAAATACCTTGCTGGGGCAGACCCTTCTACTGTGGAAATGTGTTACCCTCCTATCATTCAGAGTGGTGGCAACTATAATCTCAAGTTCAGTGTGGTGAGTGACAAGAATCATATGCACTTTGGGGCTATCACTTGTGCCATGGGTATTCGCTTCAAGTCTTACTGCTCCAACCTTGTTCGCACTTTGATGGTTGATCCTTCTCAAGAAGTTCAAGAAAATTATAACTTTTTGCTCCAGCTTCAAGAGGAGCTGCTGAAGGAATTAAGACATGGTGTGAAGATATGTGACGTGTATAACGCTGTCATGGACGTGGTTAAAAAGCAGAAGCCAGAACTGCTGAACAAAATTACCAAAAACCTAGGGTTTGGGATGGGAATTGAATTCCGTGAAGGCTCCCTAGTAATCAATAGCAAAAATCAATACAAACTGAAGAAAGGAATGGTTTTCAGCATCAATTTAGGATTCTCAGACCTGACTAACAAGGAGGGGAAAAAGCCAGAAGAGAAAACCTATGCCCTGTTCATTGGTGACACAGTGCTTGTGGATGAGGATGGCCCAGCTACTGTTCTCACTTCTGTGAAGAAGAAAGTGAAGAATGTGGGGATTTTCCTAAAGAATgaagatgaggaagaagaggaggaggagaaagatgaggcagaggaCCTTTTGGGAAGAGGTTCTCGGGCAGCATTACTTACAGAAAGAACAAGAAATGAAATGACTGCAGAAGAGAAGCGAAGAGCACATCAGAAAGAACTAGCGGCTCAACTCAATGAAGAAGCAAAGAGGCGATTGACTGAACAAAAGGGAGAACAGCAGATTCAGAAAGCTCGCAAGTCTAATGTGTCCTATAAAAACCCATCTCTGATGCCTAAGGAACCACATATTCGGGAAATGAAGATCTACATCGATAAGAAATATGAGACTGTAATAATGCCCGTGTTTGGCATTGCAACACCGTTTCACATTGCCACAATCAAGAATATAAGTATGTCCGTGGAAGGAGATTATACTTACTTGCGAATCAACTTTTATTGCCCAGGCAGTGCTCTGGGCAGGAATGAAGGCAACATCTTTCCTAACCCTGAAGCGACTTTTGTCAAGGAAATTACATACCGAGCATCAAATATTAAGGCACCCGGAGAACAGACAGTACCAGCCTTGAACCTTCAGAATGCTTTCCGAATTATTAAAGAAGTACAGAAACGTTATAAAACTCGAGAAGCTGAAGAGAAAGAGAAGGAGGGGATTGTAAAACAAGACTCACTGGTGATCAATCTAAACCGGAGTAATCCGAAACTGAAAGATCTATACATTCGCCCAAATATTGCCCAAAAGAGGATGCAAGGCTCACTGGAGGCCCATGTCAATGGCTTCCGCTTCACATCTGTTCGAGGAGACAAAGTGGATATTTTGTACAATAATATTAAGCATGCTTTGTTCCAGCCCTGTGATGGAGAAATGATTATTGTCTTGCACTTTCACCTCAAGAATGCCATCATGTTTGGGAAGAAGCGGCACACGGATGTGCAGTTCTACACAGAAGTGGGAGAGATAACCACGGACTTGGGGAAACATCAGCATATGCATGACCGAGATGACCTCTATGCTGAGCAGATGGAACGAGAAATGAGGCACAAACTGAAAACAGCCTTTAAAAATTTCATTGAGAAAGTAGAGGCTCTAACTAAGGAGGAACTGGAATTTGAAGTGCCTTTTAGGGACTTGGGATTTAACGGAGCTCCCTATAGGAGTACCTGCCTCCTTCAGCCCACTAGTAGTGCGCTGGTAAATGCTACGGAATGGCCACCTTTTGTGGTGACATTGGATGAGGTAGAGCTGATCCACTTTGAGCGGGTCCAGTTTCACCTGAAGAACTTTGATATGGTAATCGTCTACAAGGACTACAGCAAGAAAGTGACCATGATCAACGCCATTCCTGTAGCCTCTCTTGACCCCATCAAGGAATGGTTGAATTCCTGCGACCTGAAATACACAGAAGGAGTACAGTCCCTCAACTGGACTAAAATCATGAAGACCATTGTTGATGACCCTGAGGGCTTCTTCGAACAAGGTGGCTGGTCTTTCCTGGAGCCTGAGGGTGAGGGGAGTGATGCTGAAGAAGGGGATTCAGAGTCTGAAATTGAAGATGAGACTTTTAATCCTTCAgaagatgactatgaagaggaagaggaggacagtgatgaagatTATTCATCAGAAGCAGAAGAGTCAGACTATTCTAAGGAGTCATTGGGTAGTGAAGAAGAGAGTGGAAAGGATTGGGATGAACTGGAGGAAGAAGCCCGAAAAGCGGACCGAGAAAGTCGTTACGAGGAAGAAGAAGAACAAAGTCGAAGTATGAGCCGGAAGAGGAAGGCATCTGTGCACAGTTCGGGCCGTGGCTCTAACCGTGGTTCCAGACACAGCTCTGCACCCCCCAAGAAAAAGAGGAAGTAACTTCTGAACTTTGGCCCTGAGCTCCATTCTTCCTCCAGCCAACCCCTGAAAATTTTACATGACATAGAAACTGTATTTTTCCTTTCGTTTTCATTTGAAGTTTTGCCATTTGTGTTTATGGGTTTAGGGGGCCATTTGTGTGGACCAATCTACTCGGGGAATTCCAGGCCCACCAGGACACGTGCCAATGGCCCCATTCAGATGGCAAGGGAGGAGGTGTTCTTGAAGACAGGAGGAGGCTCCCGCTGTTAATAAATATTGTTTCATTCTTCTCTCTTCCTGTCACCTTCTGCCAAGACATTGATGGCTTCTGACATCTTATTTGGTGTCTCAAAGCTGTATTTCCAAGACAGTGGTACAAGGTGACCCTTAATTACCCGTATCATGGTTCTTGACCAGCACATTCAATCCTCCAACCTACCCTACTGCCATGACCTTCCGCACATCTCTAAGTTTTATCTTTGCAATACTCAAGGTTCTCGGAAATTTGCTAATGGTTGTGATAAACCATACAGCTTGAGCCAGTGAGGCAGATTGGGCTGGTGCCTTCGTCTGAGTTTTCCTGCTTTCCTGCCTCGTGCAGATTCTGAGGTATATCTGCTGCCTTGGAAGACATAAGAAGCAGTGATACTCCCTGGCTCGGTTATTTTCTCCATACAATGCACACATGGTACAATGATAGAAGGCAAAATTGCCACTGTCTTCTTTTTTTTCTCATATATCTAAGGAAGATATATCAGGTTGTGCCTCATGTACCGCTTCTAGTGAAATGTAGAGGAAGGCTCAAAGGAGTCAACATTTATATCTGGAAGGGACAAGTCATGCCTTGGGCCTAGAATACCCTGATGAGAAAAGAGAAGAGGAAGGGAGGCCATATCTACAACACAGCCTCTCGGCACTGCTGCTCCTTATTTTAACTTTGTCTTGCATTGTCCTGTATTTATCACAGTTTCTGTTGAACAGCTTTTCAAGTATTTGGGGAGTTTATCTTGCCATCCTCCCCTTCTGGTTCTCTGCACCCACCTGTCCCACTGCAGTTCCTTCCGTGCTCTGTGACTTTAAGAGAAGAAGGGGGGAGGGGTCCCGGATTTTATGTTTGTTTGTTTTTTCTCCTTAGCAGTAGGACTTGATATTTTCAATTTTGGAAGAACTAAAAGATGAATAAACTGGGTTTTTTTTGTTGTTTGTTTTTGTAAATTCA

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