Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name TIMM17BP1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:17400395-17401186  UCSC
Coordinates (T2T) chr12:17276639-17277430  UCSC
Coordinates (hg19) chr12:17553329-17554120  UCSC
Strand +
Parental Sequence NM_005834.5
Parental seq. overlap 735 bp
Parental seq. overlap (%) 77.5%
Genomic Region Intergenic
Retrocopy Summary TIMM17BP1, located on chr12:17400395-17401186, is a retrocopy of the parental gene TIMM17B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TIMM17B
Full Name translocase of inner mitochondrial membrane 17B
Also known as DXS9822|JM3|TIM17B
Coordinate chrX:48893447-48898143
Strand -
Gene summary This gene encodes a multipass transmembrane protein that forms an integral component of the mitochondrial translocase TIM23 complex. This complex facilitates the transport of mitochondrial proteins from the cytosol across the mitochondrial inner membrane and into the mitochondrion. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TIMM17BP1
Bonobo Pan paniscus TIMM17BP1
Gorilla Gorilla gorilla TIMM17BP1
Orangutan Pongo abelii TIMM17BP1
Gibbon Nomascus leucogenys TIMM17BP1
Green monkey Chlorocebus sabaeus TIMM17BP1
Crab-eating macaque Macaca fascicularis TIMM17BP1
Rhesus Macaca mulatta TIMM17BP1
Baboon Papio anubis TIMM17BP1
Golden snub-nosed monkey Rhinopithecus roxellana TIMM17BP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TIMM17BP1
TGCCATGGAGGAGTACGCTCGGGAGCCTTGCCCATGGCGAATTGTGGATGATTGCTGTGGAGCGTTCACTATGGGTGTCATTGGTGGCGGAGTCTTCCAGGCCATCAAGAGTTTCCGCAATGACCCTGTTGGAATTCGGCACCAGTTGAGAGGTAGTGCCAACACTGTGAGGATCCGAGTTCCCCAGATTAGAGGTAGCTTCGCAGTGTTGGGGGGCCTGTTCTCCACCATCGACTGTGGCCTGGTGCGGCTTTAGGGCAAGGAGGATCCCTGGAAATCTATTACCAGTGGAGCATTGACTGGGGCTGTGCTGGTAGCCTGCAGTGGCCCACTGGCCATGGTGGGCTCAGCGATGATGGGGGGCATCCTGTTGGCCCTCATTGAGGGCGTTGGCATCCTCCTCACTCGCTACACGGCCCAGCAGTTCCAAAATGTGCCCTTGTTGCTGGAGGACCCCAGCCAGCTGCCTCCTAAGGATGGCACCCCGGCCCCAGGCTATCCCAGCTATTAGTACCACTGAGGAAGCCACTGCCACCATGGGAGCTGCTTCTCGGTTTTCTTCCCGATAATCTACCTCGAAGGAAGGGCTAGCTCCTAGTTAGCCCTGGGACCCTCCAGAGAGGGCTTCTACTCTGCTCCCTAGTCCCAGGCTGGGGGTGGGGCACTGCAGCTGCCCTGACAGATGGGTCCCCTTTTTCTCTCTCGGGGCACGCCAGCCCTACATTCCCATGTATCAAGTTCTCACCCCAGCTCCTTTGTGTGGCACTCTGATGTATATTTAAAGCCCATTTT
>NM_005834.5
TGGGGGAGCAGAGGGCAGCACTTCCTCCAGCTCCAAAAGAGTGCACCCACCCCAACGTTACCAATACACTCGTGCAGGCGGAAAGCTCCGACGCCGGTGTGCGTCTACGCTGGGGGCGTGGCCTGACTGCGCGGCCAGACGCCAGCGCCATGGAGGAGTACGCTCGGGAGCCCTGCCCATGGCGAATTGTGGATGATTGCGGTGGAGCCTTCACTATGGGTGTCATCGGTGGCGGAGTCTTCCAGGCCATCAAGGGTTTCCGCAATGCCCCTGTTGGAATTCGGCACCGGTTGAGAGGTAGTGCCAATGCTGTGAGGATCCGAGCCCCCCAGATTGGAGGTAGCTTCGCAGTGTGGGGGGGCCTGTTCTCCACCATCGACTGTGGCCTGGTGCGGCTTCGGGGCAAGGAGGATCCCTGGAACTCTATCACCAGTGGAGCATTGACCGGGGCTGTGCTGGCTGCCCGCAGTGGCCCACTGGCCATGGTGGGCTCAGCAATGATGGGGGGCATCCTGTTGGCCCTCATTGAGGGCGTTGGCATCCTCCTCACTCGCTACACAGCCCAGCAGTTCCGAAATGCGCCCCCATTCCTGGAGGACCCCAGCCAGCTGCCCCCTAAGGATGGCACCCCGGCCCCAGGCTACCCCAGCTATCAGCAGTACCACTGAGGAAGCCACTGCCACCATGGGAGCTACTTCTCGGTTCCCTCCCCGATGGTCTACCTCGAAGGGAGGGCTGGCTCCCAGTTAGCCCTGGGACCCTCCAGAGAGGGTTTCTACTCTGCTCCCTAGTCCCAGGGTGGGGGTGGGGCACCCCAGCTGCCCTGACAGATGGGTCCCCTTTTTCTCTCTCAGGGCACCCCAGCCCCACACTCACATGTACGAAGTTCTCACCCCAGCTCCTTTGTGTGGCACCCTGATGAGTATTTAAAGCCCGTTTTGAAAtgcc

Publications

PMID - Link Title