Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KNOP1P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:24583202-24585092  UCSC
Coordinates (T2T) chr12:24454010-24455900  UCSC
Coordinates (hg19) chr12:24736136-24738026  UCSC
Strand +
Parental Sequence XM_024450278.1
Parental seq. overlap 1356 bp
Parental seq. overlap (%) 61.7%
Genomic Region Intergenic
Retrocopy Summary KNOP1P1, located on chr12:24583202-24585092, is a retrocopy of the parental gene KNOP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KNOP1
Full Name lysine rich nucleolar protein 1
Also known as 101F10.1|C16orf88|FAM191A|TSG118
Coordinate chr16:19701937-19718227
Strand -
Gene summary The protein encoded by this gene is a nucleolar protein that interacts with zinc finger 106 protein. The encoded protein has several of the same characteristics as nucleostemin and may be involved in testis development. [provided by RefSeq, Feb 2017]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes KNOP1P5
Bonobo Pan paniscus KNOP1P5
Gorilla Gorilla gorilla KNOP1P5
Orangutan Pongo abelii KNOP1P4
Gibbon Nomascus leucogenys KNOP1P5
Green monkey Chlorocebus sabaeus KNOP1P2
Crab-eating macaque Macaca fascicularis KNOP1P3
Rhesus Macaca mulatta KNOP1P3
Baboon Papio anubis KNOP1P3
Golden snub-nosed monkey Rhinopithecus roxellana KNOP1P4
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KNOP1P1
CTGGGATCCCAGAGTGGTCAAAGAACCAGGGACTCAATACTCAATTTTAAACAATGATGATTACTTTGCCCATGTTTCTCCTATAAAAGCCACAGCCCCCTCTAAGAGTGTGGTCCACGGGCAGGCACCTGAGATGCCTCTAGTGAAGAAAAAGAAGAAAGAGAAGGGTGTCAGCACCCTTTGCGAGGGGCACGTAGAACCTGAGACCACGCTGCGTGCCAGACGGACAGAGAAGTCATCCAGCCCAAGGAACCAGGTGCTTGGCCATTTGGAGTTCCTCAGTGGGCAGAAGAAAAGGAAGTCATCTCTGGCCATCTCCCATGCCTCTGGGGTGAAAATCTCCCCAGACCCCAGACAGGGTGAGGAGGAAACCAGAGTTGGCAAGAAGCTTAAAAAACTTAAGAAGGAAAAAAAGGGGGCCCAGGACCCCACAGCTTTCTCAGTCCAGGACCCTTGGTTCTGCGAGGTCGGGGATGCTGTGGACACTTGCTCAGTGGGGAAGGAGGGTGAGGAACAGGTAGCCTTGGGGCAGAAGCGGAAGCACAAGAGCCCCAGGGAACACGGTGGGAAGGCGAAGAAGAAAAAAAAATCCACCAGGAGGGAGACGCCCTCCCAAGCCACTCCAAGCCCTCCAGGTCCATGGAGAGCTGCCCTAGGAAACGAAGTAAAAAGAAGCCAGTCAAAGTGGAGGCTCCGGAATACATCCCCATAGGAGATGGCCCTAAAACCCCCGCGAAGAAAAAGATGAAGTCCAAGAAGAAGGTAAAGCAGCCAGTCATTGAGGAGCCGGCTCTGCAAAGGAAGAAAAAGAAAAGGAAAGAGAGTGGGGTAGCAGGAGACCCTTGAAAGGAGGAAACAGACACGGACTTGGAGGTGGTGTTGGAAAAGAAAGGCAACATGGACTAGGCGCACATAGACCAGGGGCGAAAGGCCTTGCAAGAAGAGACTGATCGCCAGTCAGGCAAAACGGAAGCTTCTGAAACCAGGAAGTGGACGGGAAGCCAGTTTGGCCAGTGGGATACTGCTGGTTTTGAGAACGAGGAACAGAAACTGAAATTTCTCAAACTTACGGGTGGCTTCAAAAACTTGTCCCCTTCGATTAGCGATTGCAAGGTCCAACGTGGCCCTCAGTAAGAAGGTGGCCGACAGTCTGCAGCAGAGCCTGCAGCGGGAATATGGCCTGGCCATGAGCTGAAAGTACAGCCGCGGAGCCGGCCTCGGCTTCTCCACCGCCCCGAACAAGATCTTTTATATTGACAGGAATGCTTCCAAGTCAGTCAAGCTGGAAGATTAAACTCTAAAGTTTCGTCTCCCCAAAACTGCCACAATTATGTTATTCAATTGTGAAGATGAATGCCATCTGACAGTTGGCTCACATTGAACACCTGTGGAGATTAAGGACAAGGACAACTATCTTGATGGGCTTGGACAAACTGGGGCGGGGCAGCTCATGTTTCCGGAGCCAGGAGAACAAGTGAGTGGCTAAAACCTCCTGTTTTCTGTTAAACATTCCGTCCCTGTCTGAGATATCAATATGTACAGAT
>XM_024450278.1
CGGTGAGTGCCAGGGCGCGTTGCAGGCGGGCCGGCGCGGGGTGTGGAGATTGCACCAGAGGAAGTGCGCGGCGGGGAAGATGGGGAAATGCGGTCCACCCACATCCCTGAATCCGACCCCTCCAGTCGGTGTGCGCCCGCTCCGGCCTGAGGCCGCCGCCTCCAGAAAGTTTTCCCGCCTCAGAGCCGGCCCTGGGACCCCACGTAATCCCTCCCAGTCTGTTGATGCGGAGGCTTGGGCCCATGGGAGCCTTGGAGGAATGATCACCAAGACACACAAAGTAGACCTTGGGCTCCCAGagaagaaaaagaagaagaaAGTGGTCAAAGAACCAGAGACTCGATACTCAGTTTTAAACAATGATGATTACTTTGCTGATGTTTCTCCTTTAAGAGCTACATCCCCCTCTAAGAGTGTGGCCCATGGGCAGGCACCTGAGATGCCTCTAGTgaagaaaaagaagaagaaaaagaagGGTGTCAGCACCCTTTGCGAGGAGCATGTAGAACCTGAGACCACGCTGCCTGCTAGACGGACAGAGAAGTCACCCAGCCTCAGGAAGCAGGTGTTTGGCCACTTGGAGTTCCTCAGTGGGGAAAAGAAAAATAAGAAGTCACCTCTAGCCATGTCCCATGCCTCTGGGGTGAAAACCTCCCCAGACCCTAGACAGGGTGAGGAGGAAACCAGAGTTGGCAAGAAGCTCAAAAAACACAAGAAGGAAAAAAAGGGGGCCCAGGACCCCACAGCCTTCTCGGTCCAGGACCCTTGGTTCTGTGAGGCCAGGGAGGCCAGGGATGTTGGGGACACTTGCTCAGTGGGGAAGAAGGATGAGGAACAGGCAGCCTTGGGGCAGAAACGGAAGCGGAAGAGCCCCAGAGAACACAATGGGAAGGTGAAGAAGAAAAAAAAAATCCACCAGGAGGGAGATGCCCTCCCAGGCCACTCCAAGCCCTCCAGGTCCATGGAGAGCAGCCCTAGGAAAGGAAGTAAAAAGAAGCCAGTCAAAGTTGAGGCTCCGGAATACATCCCCATAAGTGATGACCCTAAGGCCTCCGCAAAGAAAAAGATGAAGTCCAAAAAGAAGGTAGAGCAGCCAGTCATCGAGGAGCCAGCTCTgaaaaggaagaaaaagaagaagaggaaAGAGAGTGGGGTAGCAGGAGACCCTTGGAAGGAGGTGAGGCGAAAGGCCTTGCAAGAAGAGATCGATCGCGAGTCAGGCAAAACGGAAGCTTCTGAAACCAGGAAGTGGACGGGAACCCAGTTTGGCCAGTGGGATACTGCTGGTTTTGAGAACGAGGACCAAAAACTGAAATTTCTCAGACTTATGGGTGGCTTCAAAAACCTGTCCCCTTCGTTCAGCCGCCCCGCCAGCACGATTGCAAGGCCCAACATGGCCCTCGGCAAGAAGGCGGCTGACAGCCTGCAGCAGAATCTGCAGCGGGACTACGACCGGGCCATGAGCTGGAAGTACAGCCGGGGAGCCGGCCTCGGCTTCTCCACCGCCCCCAACAAGATCTTTTACATTGACAGGAACGCTTCCAAGTCAGTCAAGCTGGAAGATTAAACTCTAGAGTTTTGTCCCCCCAAAACTGCCACAATTGCTTTGATTATTccatttatgctggagattacaaattttttttgtgaaaaaatcagatcttggtgaggacctcgagcagtaagatataaataactcccataagcttagcgttccagtaatggaacactaggcataaatggTTTATTCAGTTGTGCAAATGAAAGCCATCTGACAGTTGGCTCACATTGAACACCTGTGGAGATTAAGGACGAGGACAACTATATTGATGGGCTTGGATGAACTGGGGCAGGGCAGCTCATATTTCGGGAGCCAGGAGAACGAGTGAGTGCTAAAACCTCCTGTTTTCTGTGTTAAACATTCCGTCCCTGTTTGAGACATCAGTATGTacagttaacttttgttgagtgtttagcaggtactagggacatactagtgttttccttaatgtatttaatcttcataattatgaaatgggtgctattattagccccatcttatagatgaggcaactgaggttcagggataaagtaataaaattgcctggggtcacccagccactaagtgca

Publications

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