Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Summary

Retrocopy Name BRI3P2
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Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:24967028-24967507  UCSC
Coordinates (T2T) chr12:24837132-24837611  UCSC
Coordinates (hg19) chr12:25119962-25120441  UCSC
Strand -
Parental Sequence NM_015379.5
Parental seq. overlap 412 bp
Parental seq. overlap (%) 52.1%
Genomic Region Intergenic
Retrocopy Summary BRI3P2, located on chr12:24967028-24967507, is a retrocopy of the parental gene BRI3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BRI3
Full Name brain protein I3
Also known as I3
Coordinate chr7:98281673-98322398
Strand +
Gene summary Enables identical protein binding activity. Predicted to be located in azurophil granule membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BRI3P2
Bonobo Pan paniscus BRI3P2
Orangutan Pongo abelii BRI3P2
Gibbon Nomascus leucogenys BRI3P3
Green monkey Chlorocebus sabaeus BRI3P1
Crab-eating macaque Macaca fascicularis BRI3P1
Rhesus Macaca mulatta BRI3P1
Baboon Papio anubis BRI3P1
Golden snub-nosed monkey Rhinopithecus roxellana BRI3P1
Gorilla Gorilla gorilla Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>BRI3P2
GCCATGGACCACAAACCTCTGCTGCAGAAGCGGCCTCTGGCCTACAACCTGGAGTCCGTCCAGGTCAACTATGCATGCTGCCTGCACAGCTATGGCGCCAACCCTGCCAGCCCCCGCCAAGGCCCTACCCCTACCTCGTCACAGGGGTACCCACCCGCCACCCCAGGGTCTACAACATCCACAGCCAGACCACCACCTGGTACCCTGCCAACTCCATCATGGTCATGGGAAGCTGTCCCGTCTGCAGGGTCGGGGGTGCTGGAGGACTGCTTCAGCTCCCTGGGCATTTTCTTGGTCATCATCCTGTTCCCCTTTGGGTTCATCTGCCGTTTTGCCTTGAGGAAGCGAAGATGCCCCAACTGCGGAGAGACCTTCGCTTAAAGAGGACACCACACCCGGCTTTCCTACACCCAGTTCTCTTTTTCTAATGTAAATTTCGTGTATAGTAGTTTTATATAATTAAGCTTCAGAACTGt
>NM_015379.5
AGAGGGGCCCGAGCCACCCGGTCCGCCGCGTCCCCGCCGCCGCCGCCGCGTCCCCCGCCGGGgccgaccgagccgagccgggccggagcggcgggcgcggccgggccgCCATGGACCACAAGCCGCTGCTGCAGGAGCGGCCGCCCGCCTACAACCTGGAGGCCGGCCAGGGCGACTACGCGTGCGGCCCGCACGGCTACGGCGCCATCCCCGCCGCGCCCCCGCCGCCGCCCTACCCCTACCTCGTCACAGGGATACCCACCCACCATCCCAGGGTCTACAACATCCACAGCCGGACCGTCACCCGCTATCCTGCCAACTCTATCGTGGTCGTAGGAGGCTGTCCTGTCTGCAGGGTTGGGGTGCTGGAGGACTGCTTCACCTTCCTGGGCATCTTCCTGGCCATCATCCTCTTCCCCTTTGGGTTCATTTGCTGTTTTGCCTTGAGGAAGCGACGATGCCCCAACTGTGGAGCCACCTTCGCTTAAAGGGAACACCAGGCCCGGCTTTCCTACACCCAGCTCTCTTTTTCTAATGTAAATGTTGTGTACAATAATTTTATTTGATTAAGCTTCAGGACTGTTTTGTAAAGCGAGGTGGGACCGATGTGGCACACGCCAGCTGCGGTTTCCCGGAGCGTGGAGAGGCAGTGCTGCTGCTCCCGCCCGAGGCTCATGACAACTCAATAAAGCACTGCTTTTATTTTTTGCAGTCTTCAATTTGAGAAAGGTGAGAAATAATGTTTTCAATAAATGAGATTCATACCATTGTTGACCTGGTGCTGCTTACT

Publications

PMID - Link Title
No publications available for this retrocopy