Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RNF4P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:231021449-231024205  UCSC
Coordinates (T2T) chr1:230402344-230405103  UCSC
Coordinates (hg19) chr1:231157195-231159951  UCSC
Strand +
Parental Sequence NM_001185009.3
Parental seq. overlap 2656 bp
Parental seq. overlap (%) 76.2%
Genomic Region Intragenic (FAM89A)
Retrocopy Summary RNF4P1, located on chr1:231021449-231024205, is a retrocopy of the parental gene RNF4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RNF4
Full Name ring finger protein 4
Also known as RES4-26|SLX5|SNURF
Coordinate chr4:2469106-2515857
Strand +
Gene summary The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RNF4P1
Bonobo Pan paniscus RNF4P1
Gorilla Gorilla gorilla RNF4P1
Orangutan Pongo abelii RNF4P1
Gibbon Nomascus leucogenys RNF4P2
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RNF4P1
CCAGGACTTTAAAATACTGGAAATCTGTCCCGATCCAAATTCTTTTGCAAGCCAGATGATTAACCAGAGGGCACGAAAGGTTGAGAACATTCGACTTCCCTGCAAACCTTGGTATAGATCACTTCCTTTTCTGTTAGGAAACGAAAGGCACCAAAGAGCACAATGAGTACAAGAAAGCGTCGAGGTGGAGCAATAAATTCTAGACAAGCCCAGAAGCGAACACGGGAAGCAACCTCCACCCCTGAGATTTCCTTGGAAGCAGAACCCATAGAACTCGTGGAAACTGCTGGAGATGAAATTGTTGACCTCACTTGTGAATCTTTAGAGCCTGTGGTGGTTGATCTGACTCACAATGACTCTGTTGTGATTGTTGACAAAAGAAGAAGACCAAGGAGGAATGCTAGGAGGCTGCCCCAGGACCATGCTGACAGCTGCATGGTGAGCAGTGACGATGAGTTGTTGTCCAGGGACAGAGACGTGTATGTGACTACCCACACTTCCAGAAACACCAGGGATGAGGGCGCTATAGGCCTCAGGCCCTCGGGTACTGTCGGTTGTCCTATCTGCATGGACAGATATTCAGAGATCGTGCAGAATAGACGTCTCATCGTTTCCACAGAATGTGGCCATGTCTTCTGTAGCCAGTGCCTCCGTGATTCCCTGAAGAACGCTAATACTTGCCCAACTTGTAGGAAAAAGATCAACCACAAACAGTACCACTCCATTCATATATGAAGTATTCAGAGACGCCCAGGAGAGACGGATGGACAATCAGGTTCTCCAGTGGTATCTGCCTCCATTTTCCTGAGCTCAAAAAGACTGTTTTGAAACCCACGTCTGATATGTAAACTGCTCTTTTGTTTCCAACCCCTTCCTTTTGTTATCTCCAGTTTGATGCTATGGCGCTGGACCCAGGGCCCTCCCAGGCCATCTCTGTTCCTCTGGGGTGGTCCAGTTCTAGAGTGAGAGAAAGGGAGTCAGGCACACTGGGAATCGTGGTTCCAGTCTGGTTGCAGAACCTGCACATTTGCCAAGAAATTTTCCGTTTGGAAAGTTTGCCCCAGCTTTCCCGGGCACACCACCTTTTGTCCCAAGTGTCTGCCGGTCGACCAATCTGCCTGCCACACATTGACCAAGCCAGACCCGGTTCACCCAGCTCGAGGATCCCAGGTGCAAGAGTGGCCCCTTGAGGCCCTGAAAAGACCAATCACTGGACTTCTTCCCTTGAGAGTCAGAGGTCACCCGTGATTCTGCCTGCACCTTATCATTGATCTGCAGTGATTTCTGCAAATCAAGAGAAGCTCTGCAGGGCAATCCCGTTTCCTAAGAATGAAAAAGTGCAATAAAGGCCATTCGTTACCTACTTTTCAGCAGCCCACCAGATGTAGCACTATTAGTGTCCCCCTCAGAGGCTTAATGTTGCCTGTGGAGCAGTGCCCATCCCAGCCCATTTCTGCCCACCAGTTGTTCTCAGGAACCTTACCCATGCTCCAGCGTCCTTCACCTGGCACAGGACATGCAAGATAAATAGGACAGGCACATGTTTGGGTGTCCTCTCTTTTCTGATAAAATCCATCCGGTGTTTGCCACACGCCCTCCAGTCCTCAGTTCCCACTGCCTAACATCTGCCCCCCGTGTAGATACTGAGAGGTGGTGGCAGTAATTGTGGCCTTATCAGCCGCTCAGTTCCAGCCTTTTGCCCAGGTCACTGTTGCCCCATGTTCGGAGAACCTGGCCCACCTGACTTGGCTTTCTCATCCTTCCCAACCCCGTGCCGTTTATTTCAGAAGCCCACTGGGCTTGGATGCTTTGGGCCTTTGACTGCTCCATAGGTTATGACTGGTGAAACAGGGGCCCAGAGGACAACCTCTCCTTCACTCCACAGGTAGGTGGGAGCCTCAGGTTCGCTCAGGGGCAGCAAAGTGGCCCAAGCTGCCCCTGACAGCACAGGGCCTGGCGGTGGCTAACGAGAGAGGCCTTACAGTGCCGGCATGCCTCCTCTTCCGCTGCCCTCCTTCCTCAGAGGGCTTCAAGCAAAACAAACAGCCTTTTCGTGTGAAACATCTTCAGGGTGGGAAAGGGGCCACTTCTGGCTTTGTTAGCAATAACTGACCTTCAGTTTACCCTTCTGAAGGAGAAGGGACTCAGCACAGAATTCACTTTAGACGGGGCTGAAGGAGTGTCCCTCCTCTATGTGAAAAGAAAATTGTTTTATTCTTCATTCTGACTTTTTAACTGTTTGGCTCACTTCCAGTTAGTTTGAATGAAAATAATAATTTTCTACTTGGAGTTGAAGAGGGCAGAATCCTCAGCTCCCATCATTGTGATGTGTAGCGTGTCTGCCCCCTGACTGGACATCATTGCCATTAACTTTCTTCTGGGCATCACGGGAATGTCACAATGCCCAGACTTGGAGCAAGGCAACCTTGGAGTCAGTCCACTAATAAAATATGGTAACACCCATTTTAAAATTTCTTTAAGTTTTATCCTTGAAGACAACTTCAGTGGTTAATTATAAAAGTTGTGTACTTCGTCCTAAATTAAATTGATAAAAAGATTTAAAAATGTGTTTTGTTTCTACTATTCAGAAACTGCAAACTAGGGAAAGGTTGGTATGAAAAAATGTCTTTCCTTTTTTCAATGTACATAGTTCAACTCTTTCTTTGTTACATTTAAACTACATCCATGGATATCAGTCTGCTTTGGACTCCTCTGCTAGTGTTAAAGATGGAAATAAAACCATTAATTTGAACCAAA
>NM_001185009.3
AGAAGTTAGGAGGTCTGCGTCTGGGTCTCGGCTCACCCTGGGGGGCCGCGGCCATGGGGCTTAGTTCCTAGCCTAGGAAGGGAAACTGAGACTCTGGGAGGGGCAGGAACGCCCCCAAGGTCACTTGGAAAGTCGGGCAGGATGTGCTGTTAGGGGGAAGACCCGGGCAGGGTTTTTGTTCCCCGCTGACGACGCCTCCTTTGTGTGTTCGCGCCGCCGCCCCGCCATCGTGGGGCCTGCGAGTTTGCCGGGGTGCGTGGGCCGCGTGGCGGGGCCTTTTGTAGGTCGGGAGGATCTGAGTACGGGTGCGGGCCTGACCGTGGGGGCGCCGAGGTCGCAGTCTAAAACTTAGTAGGGCCTCGATTTCCGGGCGCGCTTCCGGGCCCCGGCTGGTGGTTGGTGGAACGTGCGACTGTGAGGCTTGCGGCCCAGCCCTGCACCGCTCGGGCCCTTCACCGCTCTGGCGCGCCTATAGACAGGTGTATGAAGATTCTCACGACCCGAAACAGAGTTGCTAGTAAACACCGCTTTTCCGCCTTTGATCCATCGAGGGAAGAGGGAAAAGGATAGAGCTTGGGCAAGCCGTTTTGgtggaatctcactctgtcacccaggatgcagtgcactggcgtgttctcggtctcactgtaacctctgccatctgggctcaagtgattctcctgcctcagcctccggagtagctgggattacagGACTTGAAAATACTGGAAATCTGTCCGGATCCAAATTATTTTGCAAGCCAGATGAGTAACCAGAGGGCATGAAAGGTTGAGAACATTTGACTTCCCTGCAAACCTTGGTATAGATCACTTCCTTTTCTGTAGGAAAGGAAAGGCACCAAAGAGCACAATGAGTACAAGAAAGCGTCGTGGTGGAGCAATAAATTCTAGACAAGCTCAGAAGCGAACTCGGGAAGCAACCTCCACCCCCGAGATCTCCTTGGAAGCAGAACCCATAGAACTCGTGGAAACTGCTGGAGATGAAATTGTGGACCTCACTTGTGAATCTTTAGAGCCTGTGGTGGTTGATCTGACTCACAATGACTCTGTTGTGATTGTTGACGAAAGAAGAAGACCAAGGAGGAATGCTAGGAGGCTGCCCCAGGACCATGCTGACAGCTGTGTGGTGAGCAGTGACGATGAGGAGTTGTCCAGGGACAGAGACGTATATGTGACTACCCATACTCCCAGAAACGCCAGGGATGAGGGCGCTACAGGCCTCAGGCCCTCAGGTACTGTCAGTTGTCCCATCTGCATGGACGGATACTCAGAGATCGTGCAGAATGGACGTCTCATCGTTTCCACAGAATGCGGCCATGTCTTCTGTAGCCAGTGCCTCCGTGATTCCCTGAAGAATGCTAATACTTGCCCAACTTGTAGGAAAAAGATCAACCACAAACGGTACCACCCCATTTATATATGAAGTATTCAGAGCCCCCCAGgagagacggatggacagacagacagccagGTTCTCCAGTGGTATCTGCCTCCATTTTCCTGAGATCAAAAAGACTGTTTCGAAACCAACATCTGATATGTAAACTGCTCTTTTGTTTCCAACCCCTTCCTTTTGTTATCTCCAGTTTGATGCTATGGCGCTGGACCCAGGGCCCTCCCAGGCCATCTCTGTTCCTCTGGGGTGGTCCAGTTCTAGAGTGGGAGAAAGGGAGTCAGGCGCATTGGGAATCGTGGTTCCAGTCTGGTTGCAGAATCTGCACATTTGCCAAGAAATTTTCCCTGTTTGGAAAGTTTGCCCCAGCTTTCCCGGGCACACCACCTTTTGTCCCAAGTGTCTGCCGGTCGACCAATCTGCCTGCCACACATTGACCAAGCCAGACCCGGTTCACCCAGCTCGAGGATCCCAGGTTGAAGAGTGGCCCCTTGAGGCCCTGGAAAGACCAATCACTGGACTTCTTCCCTTGAGAGTCAGAGGTCACCCGTGATTCTGCCTGCACCTTATCATTGATCTGCAGTGATTTCTGCAAATCAAGAGAAACTCTGCAGGGCACTCCCCTGTTTCCTAAGAACGAAAAAGTGCAATAAAGGCCATTCGTTACCTACTTTTCAGCAGCCCACAAGATGTAGCACTATTAGTGTCCCCCTCAGAGGCTTAATGTTGCCTGTGGAGCAGTGCCCATCCCAGCCCGTTTCTGCCCACCAGTTGTTCTCAGGAACCTTACCCATGCTCCAGCGTCCTTCACCTGGCACAGGACATGCAAGATAAATAGGGCAGGCACGTGTTTGGGTGTCCTCTCTTTTCTGATAAAATCCATCCCGTGTTTGCCACACGCCCTCCAGTCCTCAGTTCCCACTGCCTAACGTCTGCCCCCGTGTAGATACTGAGAGGTGGTGGCAGTAATTGTGGCCTTATCAGCCGCTCAGTTCCAGGCTTTTGCCCAGGTCACTGTTGCCCCATGTTCGGAGAACCTGGCCCACCTGTCTTGGCTTTCTCATCCTTCCCAACCCAGTGCCGTTTATTTCAGAAGCTTCCTGGCCACTGGGCTTGGATGCTTCGGGCTTCTGACTGCTCCATAGGTTTTGACTGGTGAAACAGGGGCCCAGATGACAACCTCTCCTTCGCTCCACAGGTACGCGGGAGCCTCAGGTTCTCTCAGGGGCAGCAAAGTGGCCCAAGCTGCCCCTGACAGCACAGGGCCTGGGGGGTGGCTAACGAGAGAGGCCTTACAGTGCCGGCATGCCTCCTCTTCCACTGTCGTCCTTCCTCAGAGGGCCTCACGCCAAACAAACGGCCTTTTCGTGTGAAACATCTTCAGGGCGGGAAAGGGGCCACTTCTGGCTTTGTTAGCAATAACTGACCTTCAGTTTACCCTTCTGAAGGAGCAGGGACTCAGCACAGAATTCACTTTAGACGGGGCTGAAGGAGTGTCCCTCCTCTATGTGAAAAGAAAATTGTTTTATTCTTCATTCTGACTTTTTAACTGTTTGGCTCACTTCCAGTTAGTTTGAATGAAAATAATAATTTTCTACTTGGAGTTGAAGAGGGCAGAATCCGCAGCTCTCATCATTGTGATGTGTAGCATGTCTGCCCTCTGACTGGACATCATTGCCATTAACTTTCTTCTGGGCATCACGGCAATGTCACGATGCCCAGACTTGGAGCAAGGCAACCTTGGAGTCAGTCCACTCATAAAATATGGTAACACCCATTTTAAAATTTAAGTTTTGTCCTTAAAGACAACTTCAGTGGTTAATTATAAAAGTTGTGTTACTTCGTCCTAAATTAAATTGATAGAAAGATTTAAAAATGTGTTTTGTTTCTACTATTCAGAAACTGCGAACTAGGGAAAGGTTGGTATGAAGAAATGTCTTTCCTTTTTTCAATGTACATAGTTCAACTCTTTCTTTGTTACATTTAAACTATATCCATGGATATCAGTCTGCTTTGGACTCCTCTGCTAGTGTTACAGATGGAAATAAAACCATTAATTTGAACCAAA

Publications

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