Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FAM98BP2
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr15). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:31954129-31955562  UCSC
Coordinates (T2T) chr12:31830099-31831532  UCSC
Coordinates (hg19) chr12:32107063-32108496  UCSC
Strand +
Parental Sequence NM_173611.4
Parental seq. overlap 795 bp
Parental seq. overlap (%) 17.9%
Genomic Region Intergenic
Retrocopy Summary FAM98BP2, located on chr12:31954129-31955562, is a retrocopy of the parental gene FAM98B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FAM98B
Full Name family with sequence similarity 98 member B
Also known as -
Coordinate chr15:38454127-38487710
Strand +
Gene summary Enables identical protein binding activity and protein methyltransferase activity. Involved in positive regulation of cell population proliferation; positive regulation of gene expression; and protein methylation. Located in cytoplasm and nucleoplasm. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM98BP2
Bonobo Pan paniscus FAM98BP2
Gorilla Gorilla gorilla FAM98BP2
Orangutan Pongo abelii FAM98BP1
Gibbon Nomascus leucogenys FAM98BP1
Marmoset Callithrix jacchus FAM98BP3
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FAM98BP2
ATGGTTAGGCTTTCAAATAAAATCATTATGCAACTTGGAAGAAAGTATGACTTCTGCTGGAAGAGATGATCTAGAGAGCTTCCAGCTTGAGGTAAATGATTTTTTTAAAAGAAATGGCATGTCCATATTCTGTACTCATATCAGGAGATACTAAAGATCATTTTAAAAAAGGAGGACTAATAAAAAAATATAAAAAGGACTGTTTGAAACTCCTATTATTTTTAAGTACAGAACTTGAAGCTTCACAGATATTACAGAACAAGAAACATTAAAATTCTCAATTAGATAAAAATAATGAAATTTATCAGGAAGTTCAAGTTCTGTGTGATAACCTTGGTGTACCCAAGTAAACAACTTCTGACATTCTGGTTATGCTAAACCAAGTGGAATCAAAGGTGAAAGACATATTTCAAATTTTTAAAAATTGTTAATTTTTTTATTAAAATTAAAGAAAACCACTCTGCTGAAAATTAATTTAAATTTGAAACAGGCAGAACAACTGGAAAGAGTCAATGATGCTCTTTCCTGTGAACATGAGTGCCTCTAGCGAATGTTATGAAACAATTAGATGCGGCAATACAGTCCGTTGCACGGTGTGATACAGCCAAGGTAAGAAAAGATGACACAGCAAGAATTTACCAGCCTCAGTGTTATGCTTTGTCACCCAAGACAGCGATTATAATGGTGCATCTACTTGCTGCTCATGATAATCTATCCAAGATCATTAGGACAAGCAGTGGAGCCAGCCAGATGATGGCATGTGCCATTAATAAGGTGCTGATGGGAAGGGTGCCTGACAGGGGAGGCTGGCCAAATGAAATTGAACCACCACCCTCTGAAATGCCCCCTTGGCAAAAGAGACAAGAAGGCAGTGGCGGAAGGGgTTTCTAAGGCAGAGGAGATGATGGTGGGAGGGGAGATTATGGTGGAA
>NM_173611.4
ACTTAGAGCGCCGAACAGCTCTGGGCCAAAGGACCATGAGAGGGCCGGAGCCGGGTCCCCAACCGACGATGGAGGGAGACGTGCTGGACACACTGGAGGCGCTGGGGTATAAAGGACCATTGTTAGAAGAGCAAGCCCTTACAAAGGCGGCAGAGGGTGGATTATCTTCACCTGAATTTTCAGAGCTCTGTATTTGGTTAGGCTCTCAAATAAAATCATTATGCAACTTGGAAGAAAGTATCACGTCTGCTGGAAGAGATGATCTAGAGAGCTTCCAGCTTGAGATAAGTGGCTTTTTAAAAGAAATGGCATGTCCATATTCTGTACTCATATCAGGAGATATTAAAGATCGTTTAAAAAAGAAGGAGGACTGTTTGAAACTTCTATTATTTTTAAGTACAGAACTTCAAGCTTCACAGATATTACAGAACAAGAAACATAAAAATTCTCAATTAGATAAAAATAGTGAAGTTTATCAGGAAGTTCAAGCTATGTTTGATACACTTGGTATACCCAAGTCAACAACTTCTGACATTCCGCATATGCTAAACCAAGTGGAATCAAAGGTGAAAGATATTCTCTCAAAGGTCCAGAAAAATCATGTGGGAAAACCACTGCTGAAAATGGATTTAAATTCAGAACAGGCGGAACAACTGGAAAGAATCAATGATGCTCTTTCCTGTGAATATGAGTGCCGCCGACGAATGTTAATGAAACGATTAGATGTGACTGTACAGTCCTTTGGATGGTCTGATAGAGCAAAGGTAAAAACAGATGATATAGCAAGAATTTATCAGCCTAAGCGTTATGCTTTGTCACCCAAGACAACGATTACAATGGCACATCTACTTGCTGCTCGTGAAGATCTATCCAAGATCATTAGGACAAGTAGTGGCACCAGCCGGGAGAAGACCGCATGTGCCATTAATAAGGTGCTGATGGGAAGGGTGCCTGACAGGGGAGGCCGGCCGAATGAAATTGAACCACCACCTCCAGAAATGCCCCCTTGGCAAAAGAGACAAGAAggcggcggtggaaggggtggttggggtggtggtggtggaggtggtggtagaggaggtggtgggggtgggggtgggagaggtggctgggggggtggaggaggaggttggggaggtggtgggggagggggaggagggtgggggggaggaggaggaggtggtagaggaggtTTCCAAGGCAGGGGAGATTATGGTGGAAGAGGGGGTTATGGTGGAAGAGGGGGCTATGGTGGAAGAGGCTATGGAGATCCATATGGAGGAggtggtggtggtggtggtggtggtggtggAGGAGGTGGATATAGAAGATACTAAAAACTATAAAAATTAGATAGCAGTGCTTGCTTCTTTATAGATACATTAGAAATAGTGTTCCAAATAACATACTTGAATATCATCTTTGAAGTAAACACCATGTTAGACTCCCTGGTGATACCACTCTTGAATTGGTTAATATGTAAGAACATTGTTTTTTATTACCAGTTGATCTCTCAAATGAAGTGATGACTTTTTCCATATTCTGTGTACCCTTGAGCATGTTGTGTCTTTTTaaaaaacaaaaaaaagaacaaaaaTTATTTTTTAAAATGTAAATATTTATTACCATCAGACTTGGAAAATGGAAAGTATTTTATTGTCATGATTGAATTTAGATTGTTACCTGTATTTTGTTCAGGTTTGAGACATATAAAAGACCCCACCTGTAATAGAAAGGAATATAGACCCTTGCCTCACCTGTATTGCTGTGGATGTGTTTTGTGGGTTTTTCATTCGATTTTACAAAATAGGGAAAGGCACTTCCAGTTGTATTTAGTAGGCAGTTGTTGTGAATCATTTTTTTCTCTTATAGGAGGAGATTCCTCTCTAGCCATGTTTCTGTTAAAGTTTCATTAATTGAAGCCCAAGTTTACTTTTTACTGTACATACTTATTTTCTAATTGGATTTGAAATCAGCATGATTTTGTTTGACAAAGCAAAGTTTAAGATTGAGGTCAGAAATACTTTAATGGAGCAAAGACACATACCAACTTTACATGACGGTGTGAGAAATAGTCCTATAAACTGGTCTCTTCATCATTTATGCTCTCACTTTAGATATCCAAATATTAAAAGGCAGGCTGACCTGTATCACACAGAATTAAGGCAGTAATTTTCTGCTTCAGTAGATCAAGGGTAGGGCTAAGGCATCCTGTGGTAATTCTGATTCACAGCTAGATTTGGGAAACACAAAGTTAGGGAATGGCTATATGTGATTTGCTAGTTGGAGCAGTCAAAGTCTTAGCTATCAAGAGTTGTGAATTTGAATCATGGCACTAGGTCAGGGGTGCTATGGATTGAAATGACCTTAGTTCTCAAGGAGTGATTTGTCCTCATTTGTCAAATGAGGAATGAGACACTTACCATCATCTCAGGTTGTTTCTTAAAGACCTAAATACAAATACAATTTGTTAAAAACTTACAGAGGGCCTATTTTGAATGCTTTAAGATGTAGGCCAAGTAATGTATTTTTCTCTTAGTGTAGAAAGTTAAGAGAAAAAGAGCTGGTACCATAAATTTTTTCAATCTTAGTGTAAAATCTGTATCTCATTGTAGGCTTCTGGTCAATACCTATACATAACAACTTAATGTGATCTAACCAACTCAACTGATAGAAAGCTGAATTGTTCCCAGTGGACAAGTGGTATTTGATGTTTAGCAGGTTTTTTTGTTGTTATTTTTTTGGTAAACTCTGTGGTAAAATCTAAAATAATGTTAAAACCCTAAAAGTAACTATTGAATATTCTGTAATCTTAGACATGTATTTTTCAAGCTAACCCTTTGAAGAAATGTGTTCAAGGTAGGAAAATATAAAATTTTTTGGTTATTTGTAAATTTATTTTTTGTGTGTTTATATTTAATGAAAAGATGTAATTTCATTTGTGATAGCTGAAAAAAAGGCTTTCCATAATTAAGAAAATACCTTTATCAGTAGCTATGAACTCTGAAAAATAATTTTTAAAAACTTTTAAGAAAAAAACTACTTGAGTAAAATATTTCAAGAGTTGTTTAAAAATCTTCTTTAAAACCTTTACATTTCTGCCTCACTTCTTTTTTGGTAGCATTAGTTGCTGATGAAGGAGATTTACAACTACTTTCAACTTTTTTACCACTAAAGGTTTATGGTAAATATGGCAGAAACAATAGTTTATCAGTTTCATTAGATTTTCCATAAGATTTCTTTGTACCTTTATAGGAGTGCTGCTTGGGTTATTCACTACAATCACTTATTTCCTATCAAAGTTTAGCACTTGCTCCTGGAATCGTGTTGGAGCTGAAACCACTCCTATGTACACATTCCTATAAACCTTAATTGAATGAAAAGCTGAATCAGGTAGACTCTTAATATTTTACTCTTTCCTGTAAGGTGGGATTTTCCTGATAATCTTTGTTCAGTAAAAATTTCTTTTGTAGAACAGTTTGCTGAGCAGTATCTGGAATAGCAGGAAGGAAATTTGGGGCCTTAATGGGAAAGGCCATAGTGTGAAAATGTTTTATAAATTGAGTGCAATACGACATGGAGTATGATGAATGGCACTCCACTGCTTCCTAAAATCCAACACTTTTTTTGATACCTCCTTTTCATTCTTTTTTGCCTGGTTCTCAATTTCATTTTTTAATTACCTCATTGTCCTTCCCCTTTTTTCTTCTCTTTTTGTCCAGCCTGGTACCTAATAGCAAATATAGACATGATCTTACTGGGAGTTTCTGCCTAAAGTAGTCATCTTTCCTCTCGACCGTATAAAGAGCATGTATTCTGTCTATAACATAATCACCACACTATTACTCATAAGCACACATCAAAAGGGAAACAAGGGTTTTCTTTGAACTTACTTTTGTTTTGCAGATCAGGGAAACCTTGCCTCATTAAACAGAAAAAGGAAAACATTTTAAATAAAAAACATCTTATTACCTGTATCTGTGACAAGAGGAGGCATGACAACCTAAAAAAAATTTGTGACCAGAAAAATGTCctgagcagtgatactatctataccttggaaggagcacaggttagagaaatgtggggatgaaaattggggaaggtgagcaggcagtttaatcttgccttcaggatcaggctgtcagtgtgactttattactttgtatgaagtattatgaattgcccaaatgataaatacacccccatctaaatgttccagaatgcattccacagaggaatttgagtgactGAAATTTTTCCTCTTTCTTCATTGGTGTGGTTAAACAAAAATTAGCTGGGGATTAAGGGAAAATTGTGGCTATGTCTGATCATTCTAAATAATCATGACCACAAATAAATTGCCCTGAGTAGGTCTGTAACCTGGA

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