Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name FABP7P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:243624589-243625118  UCSC
Coordinates (T2T) chr1:243035742-243036271  UCSC
Coordinates (hg19) chr1:243787891-243788420  UCSC
Strand -
Parental Sequence NM_001446.5
Parental seq. overlap 466 bp
Parental seq. overlap (%) 58.9%
Genomic Region Intragenic (AKT3)
Retrocopy Summary FABP7P1, located on chr1:243624589-243625118, is a retrocopy of the parental gene FABP7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FABP7
Full Name fatty acid binding protein 7
Also known as B-FABP|BLBP|FABPB|MRG
Coordinate chr6:122749201-122784074
Strand +
Gene summary The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FABP7P1
Bonobo Pan paniscus FABP7P1
Gorilla Gorilla gorilla FABP7P1
Orangutan Pongo abelii FABP7P1
Gibbon Nomascus leucogenys FABP7P1
Green monkey Chlorocebus sabaeus FABP7P1
Crab-eating macaque Macaca fascicularis FABP7P1
Rhesus Macaca mulatta FABP7P1
Baboon Papio anubis LOC100997903P1
Golden snub-nosed monkey Rhinopithecus roxellana FABP7P1
Marmoset Callithrix jacchus FABP7P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FABP7P1
CTGCAGTGGCAATAAGACCAGCAGCTCCTCACTTCTGTCTCTAAAGTGGGGAAAGGGCAAGGGTGGAGGAGGCTTTCTGTAATACCTGGAAGCTGACCGACAGAACTTTGATGAGTACATGAAGGCTCTAGGGATGGGCTTTGTCACTAGGCAGGTGGGAAATGTGGACAAACCAAGAGTGATTATCAGTCAAGAAGAAGACAAAAGGTGGTGATCAGGATTCAAAGTATGTTCAAGAACACAGAGGTTAGTTTCCATCTGGGAGAAGAGTTTGATGAAACCACTACAGATGACAGAAACTGCAAGTTTGTTGTTAGTCTGGACAGAGACAAACTCATTCACATACAGAAATGGGATGACAAAGAAACATATTTTATAAGAGAAATTAAGTATGGTGAAATGGTTATGACTTACTTTTGGTGATGATGTGGTTGCCGTTCACCACTATAAGAAGGCATAAAAATGTTCATGATTTGGAGCTGGAAGAGCTCTTTAGTTTTCCTCTTTACTCAAGTCTCAGTGCTATCCTG
>NM_001446.5
GTAAAGGGTCTTCTGAGCTGCAGTGGCAATTAGACCAGAAGATCCCCGCTCCTGTCTCTAAAGAGGGGAAAGGGCAAGGATGGTGGAGGCTTTCTGTGCTACCTGGAAGCTGACCAACAGTCAGAACTTTGATGAGTACATGAAGGCTCTAGGCGTGGGCTTTGCCACTAGGCAGGTGGGAAATGTGACCAAACCAACGGTAATTATCAGTCAAGAAGGAGACAAAGTGGTCATCAGGACTCTCAGCACATTCAAGAACACGGAGATTAGTTTCCAGCTGGGAGAAGAGTTTGATGAAACCACTGCAGATGATAGAAACTGTAAGTCTGTTGTTAGCCTGGATGGAGACAAACTTGTTCACATACAGAAATGGGATGGCAAAGAAACAAATTTTGTAAGAGAAATTAAGGATGGCAAAATGGTTATGACCCTTACTTTTGGTGATGTGGTTGCTGTTCGCCACTATGAGAAGGCATAAAAATGTTCCTGGTCGGGGCTTGGAAGAGCTCTTCAGTTTTTCTGTTTCCTCAAGTCTCAGTGCTATCCTATTACAACATGGCTGATCATTAATTAGAAGGTTATCCTTGGTGTGGAGGTGGAAAATGGTGATTTAAAAACTTGTTACTCCAAGCAACTTGCCCAATTTTAATCTGAAAATTTATCATGTTTTATAATTTGAATTAAAGTTTTGTCCCCCCCCCCCTTTTTTTTATAAACAAGTGAATACATTTTATAATTTCTTTTGGAATGTAAATCAAATTTGAATAAAAATCTTACACGTGAAA

Publications

PMID - Link Title