Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name AKIRIN2P2
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:248137302-248138152  UCSC
Coordinates (T2T) chr1:247563497-247564347  UCSC
Coordinates (hg19) chr1:248300604-248301454  UCSC
Strand +
Parental Sequence NM_018064.4
Parental seq. overlap 715 bp
Parental seq. overlap (%) 37.4%
Genomic Region Intergenic
Retrocopy Summary AKIRIN2P2, located on chr1:248137302-248138152, is a retrocopy of the parental gene AKIRIN2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AKIRIN2
Full Name akirin 2
Also known as C6orf166|FBI1|dJ486L4.2
Coordinate chr6:87674860-87702233
Strand -
Gene summary Enables enzyme binding activity and identical protein binding activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of interleukin-6 production and response to lipopolysaccharide. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AKIRIN2P1
Bonobo Pan paniscus AKIRIN2P1
Crab-eating macaque Macaca fascicularis AKIRIN2P1
Rhesus Macaca mulatta AKIRIN2P1
Baboon Papio anubis AKIRIN2P1
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AKIRIN2P2
AGGACTTCATCTATAACATCCTCACCATTAAATAAAGACAGGTCTTGTCTACTCTAGGGCAGGATGGGTAGGTCTGTGAACGTTTTCTGAAAGAATGTGATGAGAAAATTCGAGAAGAGCGTGAAGAAATCAAACACAAAACTGGCAGAACAGGATGAGGCATTTGTGAAGTTCACGCTTGGGGAAATAATGTGACGCTCTGGCGCTGGCTCTTACGTTTCATGACTCACACATTCTGCATTTGCCGCTGCCTTATTCCTTGCTGACTTATTGCAAAGGGTCCCAATTTTGTCCTGACACAATGCCAGGATCCCTCGGTGAATACAGGTTTTTGCAAGCTTTTGACAATGGCAACCACTCTCAGGCCCTAGCAACTGGTTTGGGACATTTCCCCGATCTCAGCACCACTTAATGTGGACCTTTGCTACCTATATTAATACAGTTTTGGCTCCTTATTTTAATATGTTTGAAAAGGATTAAAGGGGGATATTCTAAAACATATCCTTCGCTGGTTGTGTAAATGAAACTAGAATGACAATGCAGAGGAAGTTAGTGTGATTTTAATTGTGTGGTACAACCAGTACATAACCAGTTATTAAAAATTGAGAAAGTAATCCCAGGACAATCTGAAGCAAATAGCCACAGCACTTCTTGAGAAATAGTGAAGGGGGAAGCCATTCCTGTATTCCAGGAGTTCTTGGGCATTCAGAATGGGTTTGTGATTTTTTTAAGTGTTTTATTTTTTCTATCAGTCTTTTAAACACATGTTTATTACGGCATTTTTTCCAGTATATTATTGTTTTACCTCTTTGGTAGTACTGGAATTTAGTTTAAAGAATAGAACATTTACT
>NM_018064.4
AGAGTTCTACGAGGGAGGGGAAGCGGTTGGACGTGTTCGCTTGGGTTCCTGCTGCGGCAGCTACCTCGCAATCTCTCTGCATCGATCGCCGCTCGCAAGCTACTGACCGTACTCGGGCGTATTAGGAGCCGCGTTCCAGCCTCACACCCCACGGTGCTGTTTTCGACTTCAGAAAGGATCTAGTCTCAGCACAGAAGCGCCTCAGGCGCGGCGCAAAGCTCGAGCGGACGGCGGGGGCGGCCGGAGCCTCTCTCGGGGGAGCCGCGCCTGAGGAGGCGGAAGAACCCCCCTGACGCGACTGGCGTGTGCTTCTGCCCGCCACCGCCCCTCCCGCTCTCACCCGGGCCGTCCCTGGCCACTGCCCCTGCCGCGGAGGCAGCGGCGGCAGCGGCTCTCCTTTCCACAGCCGGCGCTCCGCGACCCGCTTGGCTCCTGAGCCCGTCGGGTAGGCTCTCCTCGAGTTCCCGCTCTTCACCCCTTCCCTCACCCTCTTCTTTCGTCACCCGTCCCCGACCCCACCCGAGCCCGGCGCCTCAGCTGCCCCCGGCCATGGCGTGCGGAGCCACTCTGAAAAGGACTCTGGATTTCGACCCGCTGTTGAGCCCGGCGTCCCCGAAGCGCAGGCGATGTGCGCCATTGTCGGCGCccacctcggccgctgcctccccgttgtcggcggccgcggccaccgccgcctccttctccgctgcggccgcctcgccgcAGAAGTATCTCCGAATGGAGCCATCCCCCTTCGGCGACGTCTCCTCCCGCCTCACCACAGAACAAATTCTGTACAACATAAAACAAGAGTATAAACGAATGCAGAAGAGAAGACATTTAGAAACGAGTTTCCAACAGACAGATCCGTGTTGTACTTCTGATGCACAGCCACATGCATTTCTCCTCAGTGGACCAGCTTCACCAGGGACTTCATCTGCAGCATCCTCACCATTAAAAAAAGAACAGCCCTTATTTACTCTACGGCAGGTTGGGATGATCTGTGAACGTTTGTTGAAAGAACGTGAAGAGAAAGTTCGAGAAGAATATGAAGAAATATTGAACACAAAACTTGCAGAACAATATGATGCGTTTGTGAAGTTTACGCATGATCAAATAATGCGACGATATGGAGAACAGCCTGCTAGCTATGTTTCATGAATCACGTATCCTGCATTTGTGGGCTGCCTTGTTCCTTGTTGAGTTGTTGCAAGAGGTCCCAATTATGACATGCAGCAATGCCAATACCCCTTCTGTGAATACAGGTTATTTCAAGCTTTCGTCAGTGGCAACCACTCTTAGGCAGCAGCAACTGGTTTTGGAAATTTCCCTGATGTCAGTACCACCTGGATGTGGACCTTTGCTACCTGTATTAATACCAGTGGCCTCATTTTGCTGTATCATTACAATTTGGCTTCTTATATTAATGTTTGAAAAGGATTAAAGCTGGTATTCTAGAACATGCCCTTCACTGGTTGTGTAAATAAAACTGTAGAATGACACTTCAGATGAAGTTAGTGTGATTTTAATTGTGCACTACAACCGAGCTGTAACCAGTTACTAATTTTAGAATGTAATCCCAGGACAATATTAAGCAAATAGCCTGCAGTGCTTCCTGTGAAATAGTGAAGGAGGAGGGCATTTCTGTATTCCAGGACTTCTTGGGGTTTCAGAATGGGTTTGTATGAttttttttttttttgtagttttatttattCTATCAGTCTTTTTAACAAATGTTTATTGCTGCATTTTTTTTTTTCCAGTGTATCATTGTTTTACTGCCCTTGTAGTACTGGAATTTAGTTGGAAGAATAAAACATTTACTTCTATTTTGCTTGTTTCTTAATGTACAGATGGGGTTAGTATTTGAATAAAGTTGGTGTTTTAAAACGTAA

Publications

PMID - Link Title