RCPedia: Rtcs

Summary

Retrocopy Name	SCO1P1	Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr12:48159068-48160884 UCSC
Coordinates (T2T)	chr12:48120424-48122240 UCSC
Coordinates (hg19)	chr12:48552851-48554667 UCSC
Strand	-
Parental Sequence	NM_004589.4
Parental seq. overlap	1061 bp
Parental seq. overlap (%)	11%
Genomic Region	Intergenic
Retrocopy Summary	SCO1P1, located on chr12:48159068-48160884, is a retrocopy of the parental gene SCO1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	SCO1
Full Name	synthesis of cytochrome C oxidase 1
Also known as	MC4DN4\|SCOD1
Coordinate	chr17:10672474-10697533
Strand	-
Gene summary	Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. [provided by RefSeq, Jul 2008]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	SCO1P1
Bonobo	Pan paniscus	LOC100988585P2
Gorilla	Gorilla gorilla	LOC101138570P1
Orangutan	Pongo abelii	LOC100436478P1
Gibbon	Nomascus leucogenys	LOC100601318P1
Green monkey	Chlorocebus sabaeus	LOC103242389P2
Crab-eating macaque	Macaca fascicularis	LOC102116067P1
Rhesus	Macaca mulatta	LOC722074P1
Baboon	Papio anubis	LOC101010807P1
Golden snub-nosed monkey	Rhinopithecus roxellana	LOC104675130P1
Marmoset	Callithrix jacchus	SCO1P1
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>SCO1P1
GCAACCTACAGAATGACCTTTGCACCATTGTACCATGAGAATGTTTCTATTTTGGATTGGCATGTTACTCCTGGGTTCAGTCAAAATAGACTCTTGAAACTGTAAGATTACAACTCAAAGTCTCCCAGGTAGCTGTGGTGAGACCAGAGGACCAAGTCTAAATGAAGTCAGTGAAGAGTGGAGGACGCTCATGGAAGGACACAGCAAGGGAGGCACAGCCAGTGCATCTCCCATTATGAATGGGCCCTCCCAGCAGCTTTATTGGCTCTCCAGTGTTTTGGACCCTTGCTCATACAGGCTGTGGAACTGAATTTCACAGAAAAGAATAATTTTTATAGCACTTTGGCTTCTCTCTTCTTGAGTTATTTGCTCTTCTGTGTTCTTGGTGGCTGATGATAGTCAGATTAGGCTCTCTGCCATTCAAAGTTTATCTTTGTACTTGAAAGCATAAGTTTTGTCTTCTTTGTTAATGAATATCACTGTCAGGCTTGCTCCACTGCCCTATCAGCAGGTACTGATTTGACTAATAAAGATGAGATCTATTGTTTGGGGGGAAAAAAAGTTAGTTTGATTTCTCTAGGGGTCTCTTATGTGATTTTTAGCTAAGTGATGGGCTAGGTTTTCAATGACATGCCAAATGGAAATAAGAAGATATTGATCATGAGTGTGACATAGAGTAGTTTTCTGCATATACTGAGCCCCTTGAAGCCCAGGCCTATTTCTTGGAAGTCTTTAGCATTCACATTTGCTATCTGAGGAGGTTTACTGCCTGGAGTGAAGTATTCAAAATAGAAAAGACAGAGAAGCTAGAGAAGGAACAGCAGTGAAGCATCAACAAGCCTTTACTGGGGGACCATTTTCCCTCACAACACATTTGGAGAGCCTGAAACTGACAAAGACTACCTGGGTCAGTGGCTGTTGATTTATTCTGGTTTCAGTCATTACTGATATCTGTCCAGAAGAACTAGAAAAAAATAATTCAAGTTGTGGGTGAGATAGTGTTCCAACTCTGCCAAATTTAACTTTTCATCACCATTGACCCAGAGAGGGACATAAAAAAGGCCATTGCAAATTATGTGAAAGAATTTTCTCCCAAACTGGTTGGCCTGATTGGCACGAAAGAAGAGATCAATCACGTGGCCAGAGCATACAGAGTATATTACAGCTCTAGCCCCAAGGATGAAGATGAAGACCATGTTAGTGAATCATACAATAACAATGTCTTTGATTGGGCCAGATGGTGAGTTTCCAGATTATTTTGGCCAGACCAGGAAGAATGCAGAAATTGTTAGCCAGTTCAATTGCTGCACACATGAGGGCACACAGGAAAAAAGAGCTAGCCAAAGCAGTGATGCTGGGTGCAATATTCTCTTGTTAAAGAGGAAGGAAGCAg

>NM_004589.4
CAAAGGAGACCCGGTCTCCGAGGCTCATGGCGATGCTGGTCCTAGTACCCGGACGAGTTATGCGGCCTCTGGGTGGCCAACTTTGGCGCTTCTTGCCTCGCGGACTCGAGTTTTGGGGCCCAGCCGAGGGGACTGCGAGAGTCTTGCTGAGGCAGTTCTGCGCGCGGCAAGCGGAGGCGTGGCGTGCCTCGGGGCGCCCTGGCTATTGCCTGGGAACCCGGCCCCTCAGCACTGCGAGGCCGCCACCCCCGTGGTCGCAGAAGGGCCCCGGAGACTCCACGCGCCCCTCGAAGCCCGGGCCTGTTTCCTGGAAGTCTTTAGCAATCACATTTGCTATTGGAGGAGCTTTACTGGCTGGAATGAAGCACGTCAAGAAAGAAAAGGCAGAGAAGTTAGAGAAGGAACGGCAGCGACACATCGGCAAGCCTTTACTTGGGGGACCGTTTTCCCTCACAACTCATACTGGGGAGCGTAAAACTGACAAGGACTACTTGGGTCAGTGGTTATTGATTTATTTTGGCTTCACTCATTGCCCTGATGTCTGTCCAGAAGAACTAGAAAAGATGATTCAAGTCGTGGATGAAATAGATAGCATTACAACTCTGCCAGATCTAACTCCACTTTTCATCAGCATTGACCCAGAGAGGGACACAAAAGAAGCCATCGCAAATTATGTGAAAGAATTTTCTCCCAAACTGGTTGGCTTGACTGGCACGAGAGAAGAGGTCGATCAAGTGGCCAGAGCATACAGAGTGTATTACAGCCCTGGCCCCAAGGACGAAGATGAAGACTACATAGTGGATCACACAATAATAATGTACTTGATTGGACCAGATGGTGAGTTTCTAGATTATTTTGGCCAGAACAAGAGGAAGGGAGAAATAGCTGCTTCAATTGCCACACACATGAGGCCATACAGAAAAAAGAGCTAGCCAAAGCAGTGTTGCTGGATGCAGTATTCTCTTGCTAAGAGGAAGGAAACTGTCTCGCATAGGAGCCTATATAAATATAAACATATATACGTGCACTCTACAGAATGGCCTTCATACCATGAGAACATTTCTGTTTTGGATGGGGATGTTACCCTTGCGTTCAACCAAAATTGATTCTTGGAACTGTAAAGATTACAACCCAAAGTCTCCCAGGAAGCTGTGGGGAGACCAGAGGATCAAGCTGAAGTGAAGCCAGTGAAGAGCCCACCTGTGGAAGGACATGGCGGGGCGAGGCACAGCCAGTGCATTCCTGCCTGCGAACAGGCCCTCCCAGCAGCTTTGCCGCCTCTCCATCGTCTTGGGCCCTTGCTCAAATAGCTGTGGGACTGAATTTCACAGAAAAGAATATAATTTCCATAGTGCTCTTGCTTGCCTCTTCTTGAGTTCTTTGCTCTTCTGAGTTCTTGGTGGCTAATAACAGTCAGATTAGGGTCTCTGCCATTCAGAGTTGATGCTTGAAAACTTTAGTTTTCCTTATTAATGAATATCACTATCAGATTTGACTAATGAAGAGGAAATCTATTGTTTGGGGGAAAAAAAACATCAGTTTGATTTCTCTAGGGGTTCTTTTATGTGATTTTTAGCTAAGTGGTGTGCCAGGTTTTCAGTGACATACCAAATGGAAATAAGAGGATATTGATCACGAGTGTGATGCTGAGTACCTTTCTGCATATACTGGATTGTACTTTGTGTAAAGTAAACATACTCAGTTTTGCTGTTCAGACAAGCGTGATCTTTTTCATGGGTGATGAGTGGGTACATAGATGGCTGCACACAGTTCTCAGGAAAGAGACCCACAGGCTCCAGCGGGCAGGTGGGtgggacgcttgctgaagtgcagttccccagacccagagctgaattcactgaatctgcagtatgatgcagagacctgcttccatgacagataccccaggtgactcggatgctggcggactgggaccatcccttaagaaAGTGTTTTTTGGGGAAATAACTTgcctggcacaatggctaatgcctataatcccaaaactttgggaggccagggcctgaggattgctagaggttaggtattcaagacaagcctgggcaacatagtgagaccccccccccccgcccccatctctacagaagatttttttggcatggtggcacatgcctgtagtcctggctactcaggagactgaaatggagtatcacttgagcccaggaattcaaggcttcagtgagctataatcacaccactgcattccagcctgggcaacagagtgagaccctCTAGATATATCTATGTAGAGATACAGAAATTAAAATGAATTTAAAAATAAATAAATTTGACCCTTCTTTTGGTGTGTCAGCCATTGAAGAAAATGATTATTGAGTGATAGAATGAATCTTGGCTTTTGTTTCTAAATTTAACTGCCCTAGAATCCTGGGTTTGGCCTTTTTCTGCCAGAAGCTGCTGCCCTAGGGGCAAAGTTCTCCAAAAGTTTTTCAGTAAATCCTAAGATGCAACAAATATAATGCCTAGATAGACAACAGATTCTTTTTACATGATATGTTTCTACACGCACATGATAGAGGTCTTTTGGTTTTTAAATTCTCAATACTTAAACCTAAATATATCAAAGTAAAAGTATGTGAAAAAAAACTATGCTAgttataggttgaataatgtcccccaaaatttatacattgaagccctaatctcagtacttcagaatgtgactgtaattggagatagggtctttagagagatagttaaattaaaatgaggctgctaggttggccctaattctatatgactggtgttcttaaaataatagattagctgggcacagtggcttatgcctgtaatcccagcactttgggaggccgaggcgtgcagatcacctaaggtcaggagttcgagaccagcctggccaacatggtgaaacgtcgtctctctcctaaaaatacaaaaattagccgggcatggtagcgggtgcctgtaatctcagttactccggaggctgaggcaggagaatcgcttgaacccaggaggcagaggtggcagtgaggcaagattgcgccatcgtactccagcctgggcgacagagcaagactccgtctcaaaaagaataggagacacagtgagacgaccatgagaagccagagagaaaacagccatcttacaagccaagagagaagttgtgagaaaaaaaaaaaaaaacaaaccctgctgactccttgatttttgccttccaagctccagaactgtgaggaaataaatgtctgttgttttagccaccaaacctggtaaggcagtcctagcaagctaatacaATAGCCTGTTCCTTAATAAACAACTGCAAGATTTAGTTTATAGAAACCAGCTCGGAAGCAGTTGGTTTAGAATGACTTTCCTAGGAATCTGGTCAAGAAAGGAACTTACTAAAAGACTATTCTCATTTAACAAAAGAGATATTAAGTATCTCAAAGGCCAAATCTTTAAAAAGATTATCTGTTTTAAGCCACAAAACATTTGTGTGGATCCCTTTGCAGCAAGTTTGCTCTTAGATAAGATTCAGTCTTCGTTCTCAGCTGTTGCAGGTTAAGGCTTGTGAAATGATCCAAAAAGGGAACAGCAGCTTTTGGAGAAAACTTTTATTTGTTCTTCATTCTAGTGTCAAGTTTAAAGGCTTGAAGTCAGAATGTTAGAAGTGGGGAAGGGGACCTTAGAGGTGACGTCTTCCAGATGTTCCTGTTTATGCACAAGGGGACAGTCTCGGAGAATTAAGGCGCAAAACTCGGGTCCCAATTTCTAGGTAGGTTCCTGTTTGTTCTGCTGCTATCGTGCGCTTATGGTGACTGTGTGAATCCAACCAAAACGGAGGTTCCGTATGCCAGTGGGGCAACGTTTTTCAGCTGCAAATCTTGGGAAATCAAAAGCAAGGCTGttttttttttcttttcttttttgagacagagtttcactcttgttgcccaggctggagtgcaatggcgcaatctcagctcactgcaacctccacctcccaggttcaagcaattctcctgcctcagcctcccaagtagctgggattacaagcatgtgccaccacacccggctaattttgtatttttagtagagactgggtttctctatgttggtcagactggtctcaaactcccgacctcaggtgatccgccgcctcggcctcccaaagtgctgggattacaggtgtgagccaccacgcccggccTCAAGGCTGTGTTTCAGTGAAATATCCCTTGCAAATCTTTACCTGGGTGGGTTACAGTGTTTTCACTAGACTCTTCAATAGAATTAATATTTTAAGAAATGCCACTTGTTTATTTGAAAAGTATAAGAATCCTATCAATGCAGTAGGCATGAATGTATTCATGTGTCTGGCTGTTCATGAAGCAGCTGATATCTTAAGTGTAAGAGGTGAGATTTACTGACTACCAGTAAAATATGCGAGTTGGGAGGCTAATGATTTTAAATTGTAAATGCGTCTGCATAAGATCCTTTAAAATAGCTTTTATTGTTCTTAAATTTATGTTTAAAAGAAATTGACATTAATATTTTCAAATCATCCATAATCTCCCAAACCTTTTTTGGTTTTCTGTTTAGTACCATTTAAATCTTTGTGTATGTGTATATGAGCTACCTTTAAAAGAGCAGTCACCCATGCGAGCATTTGTTACCCAATTAGTTTGTACTTTTTTTTGGTTTTTAttttgttgttgttatttgtttctttttgagatggagtctcgctcttctcacgcaggctggaatgcaataatggcataatcttggctcactgcaacctccgcctcccaggttcaagcgattctccagcctgagtctcccgagtagctgggattacaggcgcccaccagcacacccagctaaatttttgtatttttagtagagacgggtttctccatgttggtcaggctggtctcgaactctcaacctcaggtgatccgcccgccttggcctcccaaagtgctgggattacacgcgtgagccactgcgcccggccTAGTTTGTGCTTTTTACTTACCAGTTAGGGGTTATATTACTGTGTAACAAAATGGACGGTTATTTCTATTCATTAACAAGATTCAAGTAATAGCCTCTTTAGCCACATATTCCTTAATAACACCTTTAGACCTTATAGGGGTAATTATTTTCTATATACTTTTCCAATGTATTTGAAAGTTTGTTGGCTCTTCTTCCGTAATTATACTATATCCTCAGTAAAGAAAGTTTGGCATACAGAAAAGTTGAAGGAAGAAAATTTTCAATCACTGTTGTTCCACTACCAAGAAATAATACTTGGAGGTATTTCCTTTCAATCTTCAACATGAGGATGCTAATGTCCCCCTCATAAGGGGCCTTAAAGTCACTGACTCTGTGCACTATTTCATGAGAACATTGATGTGGGTATTTAACCGAAAGAAAACTTGAGTTttctttttttcctttttattgtgaaaatttggaaacttattcaaaaagtagaatagttaactaattgatgtacccatcagcaagcttcagtgattaccaccatttaattttgtctgcacccccccacccactgccacccCAGCCCATTCCCAGCATGTGCCTCTGAAAGAGACCAACTTTGTCCTTTAAAAACAACCACAGTTggctgggcacggtggctcatgcctgtaatcccagtactttgggaagcaaaggcgggtggatcacctgaggttgagagttcgagactggcctgaccaacatggagaaacccgtctctactaaaaataccaaagttagccgggcgtggtggcgggtgcctgtaatcccagctactcgggaggctgaggtaggagaatcgtgtgaatctgggaggcggaggttgcagtgagccgagatcacgccactgcactccagcctgggcaacaagagttgtctcaaaaaacaaaaaagaaagaaagaaaaaaaCAACCACAGTTTCATCAGCACAGCAAAAAggtttttgtttttgctcttggattttgtcgtttggtttttgcttAATATCAAATATCCAGTCAGTGTAAACTCGTTTATAATTTGGTCCTTTGATTTCAAGGAGCTATGATGCAGTTCGTTGTGGGGATGTGTTGTCTCCATGTCATACATGTGACTTTGTCCATGTTTGCACCCAGTTCAAGGAAGACACAACCCTAGGGAAAGACAACCCTCCCCGCCAAGCCTCTCTTCCCATTCTTAAACATAGGGTGGCGTTATTCAGGTTGGACCAGTTTAAAAAGACTAACGCATTTGTCCTCGTTGTTGGGTGTTTTTTTTCTTTAAATTTGTAAAACAGGAATAATTGTGTTAGGATGAAGTATGATACTAGGagaacagggaaaactaacccatcgtgttaaaagtcagaatagtgcttaactctggcaggaggtgagatggttagtaattcagaagggggtgccaggagagcttccagagccattgaaatgttcagtagcttgatctgggtgatgatttacatacataaaaacatattaaactttgaacttaagatttatgccttttactgtttgcaccctataactcCAAAAGAAAAGTAGAGGGGAAAAAGAGTCCCTGCAAAAGGCAGTCTTGAAAGAAAGCAAGTCTGTGATGTGGAGAATGCATTGGACAGCTCTCAGCAATTTGCTGTAGCTTGGGCAGAGAGATAAAAGCTAATGCCAGCATCAGGTTGCCCAGGCGAGAGAAGGCCTGAAAGAAGACAGCGTGGAGAAAGTGTCAGCAAGCTTCAGCAACAGCAGGAGGCAGATGGTAGGAGAGTGGGCCTCAGGTGTGGTGTGGCAGAGCAGAGTAGCCACACTTAGGCCCCAGAGACAGTGTCTTCTCACCCTCAGTTGAAGGGGCAGGAAATCAATCGCTCTAGTCACCCCTAAGCTGGAGGACGGACCTAAAGTTGCCACAGCTTTGAGAGGCAAAGAAGTTTGCTCAGTGGCTTTTAGAGACTTCTAGGGCCCTGGGACCCTGACACTGAGGAGGAGCAAACTGAAGGGGAGAGTGGGCACATTCCTTGTTGGCTGCTGTGGTGAGCAGCAGCTGGTCGTTGTCAGTCAAGCTCCGGACCACTCTGATGATGCTCACTGCATTTTGATGGAGTAAGCCAGGGACATTACCACTGTGTTTGAGCCATCTGAAGTATTCCTGGGTGGGTCTGCAGTTGGCAGCCCGTGATCCTTTTTCCATTCAAGGATGATGCAAAGGTAAGGGGCCAAGGCTGAGCTCTGTAGATGCCTGTGAGAGCCTCCTGGTCTCAAGAGGTCATACCAAGGGCCTTGGCCACCAAGGTTTCGTGAGGACCTTGAGGTGGTTTCGCCATCACAATGTCAGACGTGTCACACACCATCTGGTATGTCCTCACTGTATAGAGGAAGAAGGGCCCAAGTGGTGAATTATCTACAAGTTTGTAGCAAAGCTAATACTCAGACTCCCTCTACAGccttgctactcagtgtagtctgtggtccggcagtgtcacaccactggggtacttagcagaaatgcagcttctcaggctccactccagctctcctcaatcacagtctgtttttttgtttgtttgtttgtttgttttgagatggagtttcgctcttgttgcctaggctggagagcagtggtgcgatcttggctcactgcaacctccacctccctggttcaagtgattctgctgcctcagcctcccaagtagctgggattacaggcgcccgccaccatgcccggtggcgtgcatggtaatttttgtatttttagtagaaacaggatctcgccatgttggccaggctggtcttgaactcctgacctcaggtgatccacccgccttggcctcccaaagtactggggattacagatgtgagccaccacgcctggcccacagtctgtattttaacaagatccccacctcagtcttaggcacatGGATTCTCCTCAACCCCCAATACCACAGAGTCTATTAATTTTTACCCAATAGGGAAGGGGAAAAAGTCAAGAAAGAATAATGAATTAAGTaatctttccccctccaggaagctctttatttaatttcgctcccatgaaacacaatttgaagagtctctcaaataaacaaattccattttctgataattatttaattgccccacttttgaaatttttgtcaaagacgactgtcactccctgtcagaacttctattcagcacagtataccaagcgtttctccatcgagttgttataatatgatcaaaaagcagggagagatgctgcttggttaccctgtggggccttatcggggctcagtgcagtctttccatgtaggcattctcaaatactcaaTTGAAACCTGATTGAGGATCATTTGATCTCTGTTGGCCCTAGTGCAGTAGGCTGCTGAGAACCACTGATGCAATAGACTGAGAGACTAACTGCCTGCTTCCCTGTCAGCCCAGGCTCTGCTAAGGCCGTCTTAGTTACAGAAGAAAGTGGGGCAGAGAGCCCTGCAAGGATTACATTCCATTCCTAACGGAGACAGGCAAGCGTTCAGTGCCCGAAGCAGGGCAGGCCTTTGTATGGCTCACTTTTCCCTGTACCAGCCTCAGCCCCGTACATTCAGAAAGCCCTGTCGGGAACGTGCGGGATCACAGCACAAGACAGTCATTCACTGATTGATTGACGACGTCAACATTGCGGAATACCTATGTTAAGCTGAGTACGAGGGATATAAAAAGTAGGCCCTGGAGAGTGCCTCTGGGATGCACATAACCAGACAAGATAAAGAAAAggcagatcacgagatcaagagatcgagatcatcctggccaacatggtgaaaccccatctctactaaaattacaaaaatcagctagacgtggtggcgggcgcctgtagtcccagctactcaggaggctgaggcaggagaatcgcttgaacccgggaggcagagattgcactgagctgaggtcatgccactgcactccagcctggcaacagggcaagactccatctcaaaaaaaaaaaaaaagaaaaaaaagaaaaaTTAGGGCAGCTTTTAGACATGAGGCCCCAAAGTGCCAACTAGTGCACCTAAACTTCAACTCTCTTTTGAGTGTTTTATGTATCTACTCAGCATCCAGTTGTAAATATGCAAAAATCAATGCCTACTGTatttaaaaattactaaattcacaataaccacacagaatctataataaatagaatcaatgtaataatgactcagatccaggggaagaaaattataaaattttggaaaaaatgatgagctattaattaagaaaatagtttgttccttggtgagaagactcaatgtaaatatgtcagttttctcctgacttaagtcttcaacacaggcctaataatattgcagtggcaaatgattGCCaggggcaggaggggatttggggaagtggtaaaaatgatctgtgtcttggtagtggtcgctgcacaactgcatacatctgtgaaaactcactgaactgcgcactttaaaagggtgaattgtaatatacatacctcaataaaccttacttaaaaaTTA

>NM_004589.4 

CAAAGGAGACCCGGTCTCCGAGGCTCATGGCGATGCTGGTCCTAGTACCCGGACGAGTTATGCGGCCTCTGGGTGGCCAACTTTGGCGCTTCTTGCCTCGCGGACTCGAGTTTTGGGGCCCAGCCGAGGGGACTGCGAGAGTCTTGCTGAGGCAGTTCTGCGCGCGGCAAGCGGAGGCGTGGCGTGCCTCGGGGCGCCCTGGCTATTGCCTGGGAACCCGGCCCCTCAGCACTGCGAGGCCGCCACCCCCGTGGTCGCAGAAGGGCCCCGGAGACTCCACGCGCCCCTCGAAGCCCGGGCCTGTTTCCTGGAAGTCTTTAGCAATCACATTTGCTATTGGAGGAGCTTTACTGGCTGGAATGAAGCACGTCAAGAAAGAAAAGGCAGAGAAGTTAGAGAAGGAACGGCAGCGACACATCGGCAAGCCTTTACTTGGGGGACCGTTTTCCCTCACAACTCATACTGGGGAGCGTAAAACTGACAAGGACTACTTGGGTCAGTGGTTATTGATTTATTTTGGCTTCACTCATTGCCCTGATGTCTGTCCAGAAGAACTAGAAAAGATGATTCAAGTCGTGGATGAAATAGATAGCATTACAACTCTGCCAGATCTAACTCCACTTTTCATCAGCATTGACCCAGAGAGGGACACAAAAGAAGCCATCGCAAATTATGTGAAAGAATTTTCTCCCAAACTGGTTGGCTTGACTGGCACGAGAGAAGAGGTCGATCAAGTGGCCAGAGCATACAGAGTGTATTACAGCCCTGGCCCCAAGGACGAAGATGAAGACTACATAGTGGATCACACAATAATAATGTACTTGATTGGACCAGATGGTGAGTTTCTAGATTATTTTGGCCAGAACAAGAGGAAGGGAGAAATAGCTGCTTCAATTGCCACACACATGAGGCCATACAGAAAAAAGAGCTAGCCAAAGCAGTGTTGCTGGATGCAGTATTCTCTTGCTAAGAGGAAGGAAACTGTCTCGCATAGGAGCCTATATAAATATAAACATATATACGTGCACTCTACAGAATGGCCTTCATACCATGAGAACATTTCTGTTTTGGATGGGGATGTTACCCTTGCGTTCAACCAAAATTGATTCTTGGAACTGTAAAGATTACAACCCAAAGTCTCCCAGGAAGCTGTGGGGAGACCAGAGGATCAAGCTGAAGTGAAGCCAGTGAAGAGCCCACCTGTGGAAGGACATGGCGGGGCGAGGCACAGCCAGTGCATTCCTGCCTGCGAACAGGCCCTCCCAGCAGCTTTGCCGCCTCTCCATCGTCTTGGGCCCTTGCTCAAATAGCTGTGGGACTGAATTTCACAGAAAAGAATATAATTTCCATAGTGCTCTTGCTTGCCTCTTCTTGAGTTCTTTGCTCTTCTGAGTTCTTGGTGGCTAATAACAGTCAGATTAGGGTCTCTGCCATTCAGAGTTGATGCTTGAAAACTTTAGTTTTCCTTATTAATGAATATCACTATCAGATTTGACTAATGAAGAGGAAATCTATTGTTTGGGGGAAAAAAAACATCAGTTTGATTTCTCTAGGGGTTCTTTTATGTGATTTTTAGCTAAGTGGTGTGCCAGGTTTTCAGTGACATACCAAATGGAAATAAGAGGATATTGATCACGAGTGTGATGCTGAGTACCTTTCTGCATATACTGGATTGTACTTTGTGTAAAGTAAACATACTCAGTTTTGCTGTTCAGACAAGCGTGATCTTTTTCATGGGTGATGAGTGGGTACATAGATGGCTGCACACAGTTCTCAGGAAAGAGACCCACAGGCTCCAGCGGGCAGGTGGGtgggacgcttgctgaagtgcagttccccagacccagagctgaattcactgaatctgcagtatgatgcagagacctgcttccatgacagataccccaggtgactcggatgctggcggactgggaccatcccttaagaaAGTGTTTTTTGGGGAAATAACTTgcctggcacaatggctaatgcctataatcccaaaactttgggaggccagggcctgaggattgctagaggttaggtattcaagacaagcctgggcaacatagtgagaccccccccccccgcccccatctctacagaagatttttttggcatggtggcacatgcctgtagtcctggctactcaggagactgaaatggagtatcacttgagcccaggaattcaaggcttcagtgagctataatcacaccactgcattccagcctgggcaacagagtgagaccctCTAGATATATCTATGTAGAGATACAGAAATTAAAATGAATTTAAAAATAAATAAATTTGACCCTTCTTTTGGTGTGTCAGCCATTGAAGAAAATGATTATTGAGTGATAGAATGAATCTTGGCTTTTGTTTCTAAATTTAACTGCCCTAGAATCCTGGGTTTGGCCTTTTTCTGCCAGAAGCTGCTGCCCTAGGGGCAAAGTTCTCCAAAAGTTTTTCAGTAAATCCTAAGATGCAACAAATATAATGCCTAGATAGACAACAGATTCTTTTTACATGATATGTTTCTACACGCACATGATAGAGGTCTTTTGGTTTTTAAATTCTCAATACTTAAACCTAAATATATCAAAGTAAAAGTATGTGAAAAAAAACTATGCTAgttataggttgaataatgtcccccaaaatttatacattgaagccctaatctcagtacttcagaatgtgactgtaattggagatagggtctttagagagatagttaaattaaaatgaggctgctaggttggccctaattctatatgactggtgttcttaaaataatagattagctgggcacagtggcttatgcctgtaatcccagcactttgggaggccgaggcgtgcagatcacctaaggtcaggagttcgagaccagcctggccaacatggtgaaacgtcgtctctctcctaaaaatacaaaaattagccgggcatggtagcgggtgcctgtaatctcagttactccggaggctgaggcaggagaatcgcttgaacccaggaggcagaggtggcagtgaggcaagattgcgccatcgtactccagcctgggcgacagagcaagactccgtctcaaaaagaataggagacacagtgagacgaccatgagaagccagagagaaaacagccatcttacaagccaagagagaagttgtgagaaaaaaaaaaaaaaacaaaccctgctgactccttgatttttgccttccaagctccagaactgtgaggaaataaatgtctgttgttttagccaccaaacctggtaaggcagtcctagcaagctaatacaATAGCCTGTTCCTTAATAAACAACTGCAAGATTTAGTTTATAGAAACCAGCTCGGAAGCAGTTGGTTTAGAATGACTTTCCTAGGAATCTGGTCAAGAAAGGAACTTACTAAAAGACTATTCTCATTTAACAAAAGAGATATTAAGTATCTCAAAGGCCAAATCTTTAAAAAGATTATCTGTTTTAAGCCACAAAACATTTGTGTGGATCCCTTTGCAGCAAGTTTGCTCTTAGATAAGATTCAGTCTTCGTTCTCAGCTGTTGCAGGTTAAGGCTTGTGAAATGATCCAAAAAGGGAACAGCAGCTTTTGGAGAAAACTTTTATTTGTTCTTCATTCTAGTGTCAAGTTTAAAGGCTTGAAGTCAGAATGTTAGAAGTGGGGAAGGGGACCTTAGAGGTGACGTCTTCCAGATGTTCCTGTTTATGCACAAGGGGACAGTCTCGGAGAATTAAGGCGCAAAACTCGGGTCCCAATTTCTAGGTAGGTTCCTGTTTGTTCTGCTGCTATCGTGCGCTTATGGTGACTGTGTGAATCCAACCAAAACGGAGGTTCCGTATGCCAGTGGGGCAACGTTTTTCAGCTGCAAATCTTGGGAAATCAAAAGCAAGGCTGttttttttttcttttcttttttgagacagagtttcactcttgttgcccaggctggagtgcaatggcgcaatctcagctcactgcaacctccacctcccaggttcaagcaattctcctgcctcagcctcccaagtagctgggattacaagcatgtgccaccacacccggctaattttgtatttttagtagagactgggtttctctatgttggtcagactggtctcaaactcccgacctcaggtgatccgccgcctcggcctcccaaagtgctgggattacaggtgtgagccaccacgcccggccTCAAGGCTGTGTTTCAGTGAAATATCCCTTGCAAATCTTTACCTGGGTGGGTTACAGTGTTTTCACTAGACTCTTCAATAGAATTAATATTTTAAGAAATGCCACTTGTTTATTTGAAAAGTATAAGAATCCTATCAATGCAGTAGGCATGAATGTATTCATGTGTCTGGCTGTTCATGAAGCAGCTGATATCTTAAGTGTAAGAGGTGAGATTTACTGACTACCAGTAAAATATGCGAGTTGGGAGGCTAATGATTTTAAATTGTAAATGCGTCTGCATAAGATCCTTTAAAATAGCTTTTATTGTTCTTAAATTTATGTTTAAAAGAAATTGACATTAATATTTTCAAATCATCCATAATCTCCCAAACCTTTTTTGGTTTTCTGTTTAGTACCATTTAAATCTTTGTGTATGTGTATATGAGCTACCTTTAAAAGAGCAGTCACCCATGCGAGCATTTGTTACCCAATTAGTTTGTACTTTTTTTTGGTTTTTAttttgttgttgttatttgtttctttttgagatggagtctcgctcttctcacgcaggctggaatgcaataatggcataatcttggctcactgcaacctccgcctcccaggttcaagcgattctccagcctgagtctcccgagtagctgggattacaggcgcccaccagcacacccagctaaatttttgtatttttagtagagacgggtttctccatgttggtcaggctggtctcgaactctcaacctcaggtgatccgcccgccttggcctcccaaagtgctgggattacacgcgtgagccactgcgcccggccTAGTTTGTGCTTTTTACTTACCAGTTAGGGGTTATATTACTGTGTAACAAAATGGACGGTTATTTCTATTCATTAACAAGATTCAAGTAATAGCCTCTTTAGCCACATATTCCTTAATAACACCTTTAGACCTTATAGGGGTAATTATTTTCTATATACTTTTCCAATGTATTTGAAAGTTTGTTGGCTCTTCTTCCGTAATTATACTATATCCTCAGTAAAGAAAGTTTGGCATACAGAAAAGTTGAAGGAAGAAAATTTTCAATCACTGTTGTTCCACTACCAAGAAATAATACTTGGAGGTATTTCCTTTCAATCTTCAACATGAGGATGCTAATGTCCCCCTCATAAGGGGCCTTAAAGTCACTGACTCTGTGCACTATTTCATGAGAACATTGATGTGGGTATTTAACCGAAAGAAAACTTGAGTTttctttttttcctttttattgtgaaaatttggaaacttattcaaaaagtagaatagttaactaattgatgtacccatcagcaagcttcagtgattaccaccatttaattttgtctgcacccccccacccactgccacccCAGCCCATTCCCAGCATGTGCCTCTGAAAGAGACCAACTTTGTCCTTTAAAAACAACCACAGTTggctgggcacggtggctcatgcctgtaatcccagtactttgggaagcaaaggcgggtggatcacctgaggttgagagttcgagactggcctgaccaacatggagaaacccgtctctactaaaaataccaaagttagccgggcgtggtggcgggtgcctgtaatcccagctactcgggaggctgaggtaggagaatcgtgtgaatctgggaggcggaggttgcagtgagccgagatcacgccactgcactccagcctgggcaacaagagttgtctcaaaaaacaaaaaagaaagaaagaaaaaaaCAACCACAGTTTCATCAGCACAGCAAAAAggtttttgtttttgctcttggattttgtcgtttggtttttgcttAATATCAAATATCCAGTCAGTGTAAACTCGTTTATAATTTGGTCCTTTGATTTCAAGGAGCTATGATGCAGTTCGTTGTGGGGATGTGTTGTCTCCATGTCATACATGTGACTTTGTCCATGTTTGCACCCAGTTCAAGGAAGACACAACCCTAGGGAAAGACAACCCTCCCCGCCAAGCCTCTCTTCCCATTCTTAAACATAGGGTGGCGTTATTCAGGTTGGACCAGTTTAAAAAGACTAACGCATTTGTCCTCGTTGTTGGGTGTTTTTTTTCTTTAAATTTGTAAAACAGGAATAATTGTGTTAGGATGAAGTATGATACTAGGagaacagggaaaactaacccatcgtgttaaaagtcagaatagtgcttaactctggcaggaggtgagatggttagtaattcagaagggggtgccaggagagcttccagagccattgaaatgttcagtagcttgatctgggtgatgatttacatacataaaaacatattaaactttgaacttaagatttatgccttttactgtttgcaccctataactcCAAAAGAAAAGTAGAGGGGAAAAAGAGTCCCTGCAAAAGGCAGTCTTGAAAGAAAGCAAGTCTGTGATGTGGAGAATGCATTGGACAGCTCTCAGCAATTTGCTGTAGCTTGGGCAGAGAGATAAAAGCTAATGCCAGCATCAGGTTGCCCAGGCGAGAGAAGGCCTGAAAGAAGACAGCGTGGAGAAAGTGTCAGCAAGCTTCAGCAACAGCAGGAGGCAGATGGTAGGAGAGTGGGCCTCAGGTGTGGTGTGGCAGAGCAGAGTAGCCACACTTAGGCCCCAGAGACAGTGTCTTCTCACCCTCAGTTGAAGGGGCAGGAAATCAATCGCTCTAGTCACCCCTAAGCTGGAGGACGGACCTAAAGTTGCCACAGCTTTGAGAGGCAAAGAAGTTTGCTCAGTGGCTTTTAGAGACTTCTAGGGCCCTGGGACCCTGACACTGAGGAGGAGCAAACTGAAGGGGAGAGTGGGCACATTCCTTGTTGGCTGCTGTGGTGAGCAGCAGCTGGTCGTTGTCAGTCAAGCTCCGGACCACTCTGATGATGCTCACTGCATTTTGATGGAGTAAGCCAGGGACATTACCACTGTGTTTGAGCCATCTGAAGTATTCCTGGGTGGGTCTGCAGTTGGCAGCCCGTGATCCTTTTTCCATTCAAGGATGATGCAAAGGTAAGGGGCCAAGGCTGAGCTCTGTAGATGCCTGTGAGAGCCTCCTGGTCTCAAGAGGTCATACCAAGGGCCTTGGCCACCAAGGTTTCGTGAGGACCTTGAGGTGGTTTCGCCATCACAATGTCAGACGTGTCACACACCATCTGGTATGTCCTCACTGTATAGAGGAAGAAGGGCCCAAGTGGTGAATTATCTACAAGTTTGTAGCAAAGCTAATACTCAGACTCCCTCTACAGccttgctactcagtgtagtctgtggtccggcagtgtcacaccactggggtacttagcagaaatgcagcttctcaggctccactccagctctcctcaatcacagtctgtttttttgtttgtttgtttgtttgttttgagatggagtttcgctcttgttgcctaggctggagagcagtggtgcgatcttggctcactgcaacctccacctccctggttcaagtgattctgctgcctcagcctcccaagtagctgggattacaggcgcccgccaccatgcccggtggcgtgcatggtaatttttgtatttttagtagaaacaggatctcgccatgttggccaggctggtcttgaactcctgacctcaggtgatccacccgccttggcctcccaaagtactggggattacagatgtgagccaccacgcctggcccacagtctgtattttaacaagatccccacctcagtcttaggcacatGGATTCTCCTCAACCCCCAATACCACAGAGTCTATTAATTTTTACCCAATAGGGAAGGGGAAAAAGTCAAGAAAGAATAATGAATTAAGTaatctttccccctccaggaagctctttatttaatttcgctcccatgaaacacaatttgaagagtctctcaaataaacaaattccattttctgataattatttaattgccccacttttgaaatttttgtcaaagacgactgtcactccctgtcagaacttctattcagcacagtataccaagcgtttctccatcgagttgttataatatgatcaaaaagcagggagagatgctgcttggttaccctgtggggccttatcggggctcagtgcagtctttccatgtaggcattctcaaatactcaaTTGAAACCTGATTGAGGATCATTTGATCTCTGTTGGCCCTAGTGCAGTAGGCTGCTGAGAACCACTGATGCAATAGACTGAGAGACTAACTGCCTGCTTCCCTGTCAGCCCAGGCTCTGCTAAGGCCGTCTTAGTTACAGAAGAAAGTGGGGCAGAGAGCCCTGCAAGGATTACATTCCATTCCTAACGGAGACAGGCAAGCGTTCAGTGCCCGAAGCAGGGCAGGCCTTTGTATGGCTCACTTTTCCCTGTACCAGCCTCAGCCCCGTACATTCAGAAAGCCCTGTCGGGAACGTGCGGGATCACAGCACAAGACAGTCATTCACTGATTGATTGACGACGTCAACATTGCGGAATACCTATGTTAAGCTGAGTACGAGGGATATAAAAAGTAGGCCCTGGAGAGTGCCTCTGGGATGCACATAACCAGACAAGATAAAGAAAAggcagatcacgagatcaagagatcgagatcatcctggccaacatggtgaaaccccatctctactaaaattacaaaaatcagctagacgtggtggcgggcgcctgtagtcccagctactcaggaggctgaggcaggagaatcgcttgaacccgggaggcagagattgcactgagctgaggtcatgccactgcactccagcctggcaacagggcaagactccatctcaaaaaaaaaaaaaaagaaaaaaaagaaaaaTTAGGGCAGCTTTTAGACATGAGGCCCCAAAGTGCCAACTAGTGCACCTAAACTTCAACTCTCTTTTGAGTGTTTTATGTATCTACTCAGCATCCAGTTGTAAATATGCAAAAATCAATGCCTACTGTatttaaaaattactaaattcacaataaccacacagaatctataataaatagaatcaatgtaataatgactcagatccaggggaagaaaattataaaattttggaaaaaatgatgagctattaattaagaaaatagtttgttccttggtgagaagactcaatgtaaatatgtcagttttctcctgacttaagtcttcaacacaggcctaataatattgcagtggcaaatgattGCCaggggcaggaggggatttggggaagtggtaaaaatgatctgtgtcttggtagtggtcgctgcacaactgcatacatctgtgaaaactcactgaactgcgcactttaaaagggtgaattgtaatatacatacctcaataaaccttacttaaaaaTTA

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