Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name TRAIPP1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:25163805-25163978  UCSC
Coordinates (T2T) chr1:25000049-25000222  UCSC
Coordinates (hg19) chr1:25490296-25490469  UCSC
Strand +
Parental Sequence NM_005879.3
Parental seq. overlap 152 bp
Parental seq. overlap (%) 7.5%
Genomic Region Intergenic
Retrocopy Summary TRAIPP1, located on chr1:25163805-25163978, is a retrocopy of the parental gene TRAIP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TRAIP
Full Name TRAF interacting protein
Also known as RNF206|SCKL9|TRIP
Coordinate chr3:49828595-49856584
Strand -
Gene summary This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TRAIPP1
Bonobo Pan paniscus TRAIPP1
Gorilla Gorilla gorilla TRAIPP1
Orangutan Pongo abelii TRAIPP1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TRAIPP1
CGAATGCCATCCTGGGTCAGAAACAGCCCAAGAGGGACAGACCAGAGCCCTGTCACAGCAAAGGTGTGGTAAGGACATCAATGGGCTTGGTGGCTGGAAAAAATTCATCCAGCCTACTGACCCAGCCATGATCCGCCCATTGCCCATTAAGTCCAAGGCCAAGGTTAAGCAGAG
>NM_005879.3
AAGTCGTGCTGCGGAGCCAAATTTGAAGCAAGCGGAGGCGCGGGGGCGCGTCTACGAAGCCGGACCTGTAGCAGTTTCTTTGGCTGCCTGGGCCCCTTGAGTCCAGCCATCATGCCTATCCGTGCTCTGTGCACTATCTGCTCCGACTTCTTCGATCACTCCCGCGACGTGGCCGCCATCCACTGCGGCCACACCTTCCACTTGCAGTGCCTAATTCAGTGGTTTGAGACAGCACCAAGTCGGACCTGCCCACAGTGCCGAATCCAGGTTGGCAAAAGAACCATTATCAATAAGCTCTTCTTTGATCTTGCCCAGGAGGAGGAGAATGTCTTGGATGCAGAATTCTTAAAGAATGAACTGGACAATGTCAGAGCCCAGCTTTCCCAGAAAGACAAGGAGAAACGAGACAGCCAGGTCATCATCGACACTCTGCGGGATACGCTGGAAGAACGCAATGCTACTGTGGTATCTCTGCAGCAGGCCTTGGGCAAGGCCGAGATGCTGTGCTCCACACTGAAAAAGCAGATGAAGTACTTAGAGCAGCAGCAGGATGAGACCAAACAAGCACAAGAGGAGGCCCGCCGGCTCAGGAGCAAGATGAAGACCATGGAGCAGATTGAGCTTCTACTCCAGAGCCAGCGCCCTGAGGTGGAGGAGATGATCCGAGACATGGGTGTGGGACAGTCAGCGGTGGAACAGCTGGCTGTGTACTGTGTGTCTCTCAAGAAAGAGTACGAGAATCTAAAAGAGGCACGGAAGGCCTCAGGGGAGGTGGCTGACAAGCTGAGGAAGGATTTGTTTTCCTCCAGAAGCAAGTTGCAGACAGTCTACTCTGAATTGGATCAGGCCAAGTTAGAACTGAAGTCAGCCCAGAAGGACTTACAGAGTGCTGACAAGGAAATCATGAGCCTGAAAAAGAAGCTAACGATGCTGCAGGAAACCTTGAACCTGCCACCAGTGGCCAGTGAGACTGTCGACCGCCTGGTTTTAGAGAGCCCAGCCCCTGTGGAGGTGAATCTGAAGCTCCGCCGGCCATCCTTCCGTGATGATATTGATCTCAATGCTACCTTTGATGTGGATACTCCCCCAGCCCGGCCCTCCAGCTCCCAGCATGGTTACTACGAAAAACTTTGCCTAGAGAAGTCACACTCCCCAATTCAGGATGTCCCCAAGAAGATATGCAAAGGCCCCAGGAAGGAGTCCCAGCTCTCACTGGGTGGCCAGAGCTGTGCAGGAGAGCCAGATGAGGAACTGGTTGGTGCCTTCCCTATTTTTGTCCGGAATGCCATCCTAGGCCAGAAACAGCCCAAGAGGCCCAGGTCAGAGTCCTCTTGCAGCAAAGATGTGGTAAGGACAGGCTTCGATGGGCTCGGTGGCCGGACAAAATTCATCCAGCCTACTGACACAGTCATGATCCGCCCATTGCCTGTTAAGCCCAAGACCAAGGTTAAGCAGAGGGTGAGGGTGAAGACAGTGCCTTCTCTCTTCCAGGCCAAGCTGGACACCTTCCTGTGGTCGTGAGAACAGTGAGTCTGACCAATGGCCAGACACATGCCTGCAACTTGTAGGTCAAGGACTGTCCAGGCAGGGGTTTTGTGGACAGAGCCCCACTTTCGGGACCAGCCTGAGGTGTAAGGGCAGACAAACAGGTGAGGGTGAGTGTGGCACCCAGAGACTGCTCTTCCTGCCCTCACCCTGCCCCACTCCTACGACTGGGAGCTGACATGACCAGCCCACTGATCCTGTCAGCAGGTCCTGCTCCTGTTGCCAGGCTCCTGTTTATAGCCATGATCAGATGTGGTCAGACTCTTTCTGGGCCTGGAGACCACGGTCACTTGTTGACTGTCTCTGTGGACCAGAGTGCTTGAGGCATCTCAGGCAGCCTCAGCCCAAGCTTCTACCTGCCTTTGACTTGCTTCTAGGCATAGCCTGGGCCAAGCAGGGTGGGGAATGGAGGATAGCATGGGATGTATGGAGAGGATGGAAGATTTTCATGtaaaataaaattaaaaaaaaaaaacaa

Publications

PMID - Link Title