Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name VTI1BP3
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:53131455-53132221  UCSC
Coordinates (T2T) chr12:53095832-53096598  UCSC
Coordinates (hg19) chr12:53525239-53526005  UCSC
Strand +
Parental Sequence NM_006370.3
Parental seq. overlap 680 bp
Parental seq. overlap (%) 13.2%
Genomic Region Intergenic
Retrocopy Summary VTI1BP3, located on chr12:53131455-53132221, is a retrocopy of the parental gene VTI1B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name VTI1B
Full Name vesicle transport through interaction with t-SNAREs 1B
Also known as VTI1|VTI1-LIKE|VTI1L|VTI2|v-SNARE|vti1-rp1
Coordinate chr14:67647085-67674632
Strand -
Gene summary Enables SNARE binding activity and chloride channel inhibitor activity. Involved in regulation of protein localization to plasma membrane. Located in several cellular components, including endosome membrane; lysosomal membrane; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes VTI1BP3
Bonobo Pan paniscus VTI1BP3
Gorilla Gorilla gorilla VTI1BP3
Orangutan Pongo abelii VTI1BP4
Gibbon Nomascus leucogenys VTI1BP3
Green monkey Chlorocebus sabaeus VTI1BP2
Crab-eating macaque Macaca fascicularis VTI1BP3
Rhesus Macaca mulatta ARG2P4
Baboon Papio anubis VTI1BP3
Golden snub-nosed monkey Rhinopithecus roxellana VTI1BP3
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>VTI1BP3
CTGATCAGAGATTTTGATGAAAAGCAACAGGAAGCAAACAAAATGCTGACACAGATGGAGGAGGAACTACATTATGCACCCGTATCTTTCCATAACCCCATGATGTCTAAGCTTCAAGACTATCAGAAGGACCTTGCCCAATTCCATCTGGAGGCAAGAAGTACACCTTTGCAGCCATGCCTGGGGACCGAGGAGACATGAAATATGGCACATATGCTGTAGAGAATGAGCATATGAATAGGCTACAGTCTCAAAGGGCAATGCTTCTCCAAGGCACCAAAAGCCTGGGCCGGGCCACCCAAGAGACTGACCAGATTGGCTCAGAAATCTCAGAAGAGCTGGGGAACCAACGGGACCAGTGAGAACGTACCAAGAGTACACTGGGAAACGCAAGTGAAAACTTGTTCAAAAGTCGAAAGATTCTCTCTTCTAAGTCCAGAAAAGTGATAACCAACAAGCTTCTGCTTTCCATCATCTCACTGGAGCTAGCCATCCTGGGAGGCTTGGTTTACTTTGTGTTCTTTTGCAAGCATGGGACTTGCAATAGGGAAGGATTGTGGACCAGAACTTTGACCTTGGGAATGCATGGTGTTAGGGATGTGGATGGAATAAGCATGTTGCTCCTGTGGGCTAACAGTTCAAGGATGCACTGCGTAGCCAGACTGTGGGGGAGAAGGGAGGAAAGGTGGAAAGCCACTTAACTGTGAAGTGACAGCAACAAGACCAGTATGATATACCAAGGTAATAATGCTGTTTATGACTTCTTt
>NM_006370.3
GCGGCTCCGGAAGAGCCTCGTCCTGGGCGGCGGTGGTGCGGCGGTCGCCGTTATGGCCACTGGGCTGGGCGGCTGACCGCCGGGCTAGGAAAGGGCCCAGGGCCCCGAATCTCGGTGGCCGCTGCTCCAGCGCGGCCTGCGCCATGGCCTCCTCCGCCGCCTCCTCGGAGCATTTCGAGAAGCTGCACGAGATCTTCCGCGGCCTCCATGAAGACCTACAAGGGGTGCCCGAGCGGCTGCTGGGGACGGCGGGGACCGAAGAAAAGAAGAAATTGATCAGGGATTTTGATGAAAAGCAACAGGAAGCAAATGAAACGCTGGCAGAGATGGAGGAGGAGCTACGTTATGCACCCCTGTCTTTCCGAAACCCCATGATGTCTAAGCTTCGAAACTACCGGAAGGACCTTGCTAAACTCCATCGGGAGGTGAGAAGCACACCTTTGACAGCCACACCTGGAGGCCGAGGAGACATGAAATATGGCATATATGCTGTAGAGAATGAGCATATGAATCGGCTACAGTCTCAAAGGGCAATGCTTCTGCAGGGCACTGAAAGCCTGAACCGGGCCACCCAAAGTATTGAACGTTCTCATCGGATTGCCACAGAGACTGACCAGATTGGCTCAGAAATCATAGAAGAGCTGGGGGAACAACGAGACCAGTTAGAACGTACCAAGAGTAGACTGGTAAACACAAGTGAAAACTTGAGCAAAAGTCGGAAGATTCTCCGTTCAATGTCCAGAAAAGTGACAACCAACAAGCTGCTGCTTTCCATTATCATCTTACTGGAGCTCGCCATCCTGGGAGGCCTGGTTTACTACAAATTCTTTCGCAGCCATTGAACTTCTATAGGGAAGGGTTTGTGGACCAGAACTTTGACCTTGTGAATGCATGATGTTAGGGATGTGGATAGAATAAGCATATTGCTGCTGTGGGCTGACAGTTCAAGGATGCACTGTATAGCCAGGCTGTGGGAGGAGGGAGGAAAGATGAAAAACCACTTAAATGTGAAGGAACAACAGCAACAAGACCAGTATGATATACCAAGGTAATAAATGCTGTTTATGACTTCTTTAAATTTACATAGTACTGTAGCATATTAATACCCTGTGAACTGCAAAAAACCAAATACATTTACAGTAGTATTGGTCACCAAAATAGAGGGGAAACTTTACAATTGTGAGAATGTGTAAATGTTCTCATTAAGGCAGTATTGACCCAGACAACCATTTAGTATTCATCTATCCCCTCAATGCCTCATAATTCTGGAATGCCTGTTGTGAAACATGTCAGTGCACAGTGTCTCCTAAATTCTCACACGTGCTTGATTTTCTGATTCATCTGGTGAACTGGGAGTAGGAAGTTGGTCATAGACAATATGCCCTCCTTCTCTTGTCTGACCAAAGCTTGAAGCAATCACATCTACTGCCAGGTTAGCTGTAGTCTTCGCCTCTTCCTCTGAGGTGGCCAACTGAGGATTGACTTCAACAAGATCCAGTGCTGATAGCAACCCTGGAAGAACAAAGTGTGACAAAACCTCAGGTTCCCTTGCTGCTACTCTCAGTGAGGGTCATCCCACTGGGACAGGGAGAACAAGCCAAAGTAAAAACAAGAGTCCATTTTATAGTAGAAAATACCTATTTTTAGGAAGCCCCTTGCACCTCATCCTCTTGGCCATGAATTTAAGTTAAAACACTGTTGTGCTATAGTAGATTAAAAGAAACCTTTTAAGATAATGAAATAAACCATCCCTGTTCAACTAACATAACAGGCATAATTGTCAGGCGTTCTGGAAAAGGAAAAGGCTTGGTGTTGGGTGGGGGAGGTTTTCATCCTGCTTGTTGGCAAAATGTATGCCACCTCCAGTATGACTAGGAACCTTCCAGATGCCTGCCTGGAAATGAATCAAGTATGAAGGCAGAGGAAATCTGCCACTTGCACTAGCCAAACTGCATTCCCACTTTTGAACTCTAATGTGTTATCTGTATCTGTTAGAGCACCACACCATATGCCCTGAAATGTAGTTATTACTGCAAACTTCATTCTCACCCCTGCAGGCCTGAGCTCTGGAGGCAGGTTCCACATCTAACAACATCTTTTTGTCTCCCAGCAGACTGACCCAGTGTCTTGTACTTGATCAAGAGAAAATTCAGCCATATGTTAATTATTTTATCTGGACTTCAGTTACCTTCTGTTAAGGTTTGAGAACTTGTGTCAAAGTTCTCGGTAGTGTTCCTTTGGCCTGGAGCAAGTGGAAGGGAAGCTTAAACCAGAAGAACCTATCCAGACCTGCTACTATGCTCACCCCTCTAAATGCCTCACTTCTCTATAGAATTTAACTTTTTAGTTGGTTATTCTGGATGAAGGGTGATCTGAACAAGCTAGTATTCAGGAATACAAGTATCTAAGAATATTTAGGGTGGCCATAAAGTCTGGAAACACAGGCAAATGTACCTAATGGTTTATTGATATTACACTATAGTACATGATGTGCTGAATGCCATCATGTCCGTTCAGCATCTTCCCTTATTAGCAATGCATAGTTGAGTGTACAGTGCCAAACTGCAACCAACAGGTGTATTACTGTAGCATTTCCATCATTTCCTGCACATGGACCTGTGTTCCTGATTTGTCTCTGATTTCCACTGACTAAACCTGCACCTTTAGCATATCCCAGAAGTGGTCATCAAAGTTTGCACTATTAGAAATATATACATGACTTATGTTTCCAGACTATTGCCACCCTATAAATTAAGCAAACTGCTTTATGTATCTAGTTGACAGCATTATAACagtgcagtggcacaatcatggctcactgcagcctcaacctcccaagtagttgggacacctggctaattattttttgtagaaacggggtcacactatgttgcccacgctggtcttgaacccctggggtcaagtaatcctcttgccttggcctcccagagtactgggattataggtatgaaccactgtgcctagccCCATGAGTGTCTTTTGGAGTAAAATATTGTAGCATAGGAACAAAGAGACAAGCCATGCCATATATAAGTGCTAGAGGTTATTAACCCCTGCTCTAAGTGGTGTTTTTAGGAAGCAAAGCAGAGAATTGAACCCCCAAGTTCTCTGGCCAATAACCTAAGGACCACTGGCAACATCTAAGATTGCAGATCTGAGAATTAGACCAGTACTGCCTGCCTTTTTGTACTGCCTAAGGTTCTGGCAGGCTGTGGCGCTAAGGAGACCATTTCTCAATGTGAGTTTCTATCCCAGCTAGTCAAGGGTTCTCTATAGCCCTGAACCTTTCAATCTGGGGTCTCTATCTATACCCTAGTTCCATCAGATGGTTACTGAAGCAGTATGATTTGGTAGTTCTTTAAATTTTGGAATGAAAGGTCATTTGAAGTAGCTTTAAAACCAGAAGCTTTCTGACAGAAATGGAAACTGTTTGCAAACAAGTATGAGTTTTGGAAAAGTAGCCAGTCTTGATAACGTAGAATTCATCTTAGTACTCTTTCCATCAGCCATTCTCATCTAACTGTATCCCCCTTATTAGAAATCCTTTCAGGCTCTAGTACAAGACCTACCCTACATAAAGGACCCAAGATATTGTCCAGTTTGCAGATTTCTTCAAGAGATCAGCTTTAGCTCCAAATTCACAACTCCCAATGAACCAATCTCTTAGAGTGCAAATTACAGCCTTGCACtcttatcttatcttgccttcttatcttaatctGCCTTTAGATAACTCAAAGAACTGCATCAGTTTGACAATTTATTCTTGTATTTAATTGTTTAAATATACAATTTTTTACTCATTATTACCTTAGTGTAATTTGGTAAGAGCCATGTCCAAGCATGACTCTAAAGGACTATATCCTTTTTATTAGCATGGCCATATAATTTTTAGCTACAAAAGTTTAAGCAAAAACAAACTCTGCAATGATGTGGAATAGCAGAAAAGATCCTTTGCAGGCAAGAGACTCTAGCATATTTACCTATGTAGTTAACAGGCTGCAGACCTGGTTGCTACATACCTGTATTGTGTATTTCCTCAGCAATATACATGCCTTCTCGATAGGTTAGTCCCCCGACAACAGGAGTTCCTGTGGCTGGAGCCAGTGTAGGGTCAAATGCATCAATATCAAAACTCAAATGGATTGGTCTTTGTCTCCTAAAAAGGAAGAGGAtaaaataatacttaaaataatacttaaCTGGTTGTCCTTGGACACTCATCCTTCTTATGGTTGCAACTCCTTGATTTTGTTGCTATTAGTCCTAGTACTTTGTTAATAAAGCTGTTAATACATTTCCAGGCTTCCTATTCTTGGAAGTTACTGAGATTGGCAATATTAACTTCCTACATACCACTTCATGATACTGCCATTTGTTCTGCATACCTCAGACAGACTAACTCCAATGTATATTTCTGCCTTACACTGGGTATTAGAACCTCTTATACTAATAACTGTCAATAGAGAGATTTCTTCACTTCTAGATGAGATTGGGCTCTCATCTAGAGACaatttaattagacaatttaaattagtctaatttaaattggcttgatgtaagttaTGGTTGCTCTTATTCTCTGAACGTAACAGCAGCTGAAGTGAACTCTAATTTTAGGTCTGCAGTTTTAACATCTTCCATTTCTAACTTCATTATAGCCCCAGTGTCCAAAGGCTGAAGCTAACAACTAAGTTTCTTAACAGCTTATGAAATGACATACTACCAGATAACAATTCTGACATTAATCACCCAGAAGTAAAGACTTGGTATTGGGAAAATGCTCTTAAAATTACCATTTGATTAGTATTCATCTGCCATCTTTCTACACTGCCAAGATTTGCTTAATATAAAACTCAGATGAAACAATCGTGAGGCTGGGAAGAATGGGACAGTTGAAACAATAAATGCTTGTCATCTCAGAAGATAAGCATTAAAGATGGAGATAAAGAAAAATTCATGAGACAGAAGATCTAGGCAATGATTTAGAGGAAACCTCCTCCCAAAAACCCCAGAGGAAGAATATGACCTGTGTTTCAAATTTTGCCTTTCTGAACTATTTAAAATTATGTGTATGTTTTTGCTTTGTATTTTAAAAGTAAAGCTGCTGTCCTCAAGAAA

Publications

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