RCPedia: Rtcs

Summary

Retrocopy Name	ERV3-1-ZNF117P1	Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr12:57966954-57969139 UCSC
Coordinates (T2T)	chr12:57935633-57937818 UCSC
Coordinates (hg19)	chr12:58360737-58362922 UCSC
Strand	+
Parental Sequence	NM_001348050.2
Parental seq. overlap	1866 bp
Parental seq. overlap (%)	22.6%
Genomic Region	Intergenic
Retrocopy Summary	ERV3-1-ZNF117P1, located on chr12:57966954-57969139, is a retrocopy of the parental gene ERV3-1-ZNF117. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	ERV3-1-ZNF117
Full Name	N/A
Also known as	h-PLK
Coordinate	chr7:64971776-65006746
Strand	-
Gene summary	This locus represents naturally occurring readthrough transcription between the endogenous retrovirus group 3 member 1 (ERV3-1) and the zinc finger protein 117 (ZNF117) genes on chromosome 7. Readthrough transcripts may encode the same protein as the ZNF117 gene. [provided by RefSeq, Jan 2017]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	LOC468808P2
Bonobo	Pan paniscus	ZNF681P2
Gorilla	Gorilla gorilla	LOC101127741P1
Orangutan	Pongo abelii	ZNF681P1
Green monkey	Chlorocebus sabaeus	LOC103234271P5
Crab-eating macaque	Macaca fascicularis	LOC102132491P1
Rhesus	Macaca mulatta	ZNF430P1
Baboon	Papio anubis	LOC101011283P1
Golden snub-nosed monkey	Rhinopithecus roxellana	LOC104669300P1
Gibbon	Nomascus leucogenys	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>ERV3-1-ZNF117P1
TCTCTGTTTCTTCTGCTTCTAGAGGCCCAGCCTCTGTGGCCCTGTGACCTGCAGGTATTGGGAGATCCACTGCTAAGATGCCAGGACCCCCTGGAAGCCTAGAAATGAGATCATTGACATTTAGGGAGGTGGCCATAGAATTATCTCTGGAGGAATGGCAATGCCTGGACACTGCACAGCAGAATTTATATAGGAATGTGATGTTAGGGAACTACAGAAACCTGGTCTTCCTGAGTATATTGCTGTCTCTAAGCCAGACCTGATCACCTGTCTGGAGGaGCCCTGGAATATGAAGAGACATGAAATGGTAGCCAAACCCCCAGTTTTATGTTTTTCTTTTGCCCAAGACCTTTGGCCAGAGTAGGACACGGAAGTTTTTTTTCCAAAAAGTTATACTGAGAAGATATGGAAAATGTGAACATTAGAATTTACAGTTAAGAAAAGTTATAAAAGTGTGGATGAGTGTAAGGTGCACAAAAAAGGTCATAATGGACTTAACCAGTGTTTGACAACTAATGAGAGCAAAATATTTAAATGTGATAAATGTGTGAAAGTTTTTTTATAAATTTTCAAATTCAAATAGACATAAGATAAGACATACTAGAAAGGAATCTTTCAAATGTGTGTCAAACATTTTGCATGCTTTCACACCTAATTCAACATAAAAGAATTTACACTAAAGACAATTCCTACAAATGTAAAGAATGTGGCAAAGCCTTTAACTGGTCCTCAGGCCTTACTAAACATAAGATAATTCATATTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCGAAGTTTTTTAACCAGTCCTCGCACCTTACTATTCATAAGACAATTCATACTGGAAAGAAACCCTACAAATGTGAAGAGTGTGGCCAATTTTTTAACTGGTCCTCACACCTTACTATACATAAGTAATTCATATGGGAGAGAAACCCTACAAACGTGAAGAATGTGGCAAAGGCTGTTAACCAATTCTCAAACCTTACTAAACATAAGAAAATTTATACTAAAGAGAAAACCTCCAAGTGTGAAGAATGTGGCAAATCCTTCAGTGAATCCTCAATTCTTAAGAGACGCAAGATAATTCATACTGGAGAGAAATTCTACAAACCTGAAAGATGTGACAATGCTTTTGGCAACACTTCAAACTTTTCTAAACATAAAATAAATCATACTGATGAGAAATCCTAGAAATGTGAAGAACGTGACAAGCCTTTAAATGGTTGTCACACTTGATTATAGGTCGGATAATTCATAGTGGAGAAAACTCCTACAAATGTGAAAAATGTGGCAAAACTTTTAACCAATCCTCACACCTTATTGCACAGAAAAGCATTTATACTTGAGAAAAAATTAACAAACAAAAAGAATGTAAAAAAGCCATTAATATCTGTTCACATCTTACTATCAGAGAGTTCATACTTAGTGAAAGCATTGTAAGTGCAATTACTGTCAAAAATGTTTTTCAGAAAATATAAGCTTTTAAAGTGAAGAAAACTATGTATTTTGAAGACAACATTATAGATATAAAGAAGGTTGTAGCACCTTTACTTGTATCACAGATCTTATTGTACACATTTTTACTACAAGAAGAGCCTGAAGCAGTTGCTTAAACTTTGTTCAACATCAAAGAATTTATATTGAAGAAAAACCCGGCAAATGTAATAAATTTGGAAAAACATTTTTTTAATAACTACAGCTTAAAAAATACCAGAGAGTTTATACTAAAATATAATTTTGCAGATGCAGTAAACTATGTAAATATCAGAGAATTCAGAGTAGAAATAACTAAGGCACCAACACTTCAGACATTACACTAAATCAGAGTACTGAGTAGAGAAAATAATCCAAAACCAAAGCTGGTAGACAAATTATTTGTATATAATGAAAAAGGAGTAGAAGATTTTTTGAAGAGTTATAATTATGTTTAAAGTATACTTTTTTTGAAAAATCTGCTACTTTAAAAAAAAATTCAATAATGATATAATTCAACTCTAAAATTACTTCATGCTGTTTCTTCATTCCTATTGTGTTTACATGTGAAAGCATGTGATAAATTGTTTCTGCATTAAAGACATGACAGATTCTTTTTTATTAGGTGGACATTATTTATGACCTTTTCTATGGAGGAGTAATGACATTAAAATGTAAAATGCATGAT

>NM_001348050.2
GTCCAATCAGGCACTCAGCTGGAGCAGACAGGACGGCTTCCGGGTTTGGTGGGGCCTTTGTCTCTGGCGGCAGCCGGAGCTTCTGGTGTAGTCTTCACTGCTCTGTGTCTTCTGCTCCTAGAGGCCCAGCTTCTGTGGCCTCGTTACCTGCAGGTATTGGGAGATCCACAGCTAAGACGCCAGGACCCACTGGAAGCCTAGAAATGGGACCATTGACATTTATGGATGTGGCCATAGAATTCTCTTTGGAGGAGTGGCAATGCCTGGACACTGCACAGCAGAATTTATATAGGCATGTGATGTGAGAGAACTACAGAAACCTGGTTTTCTTGGGTGAAGGTATTGCTGTCTCTAAGCCAGACCTGATTACCTGTCTGGAGCAAGGAAAAGAGCCCTGGAATATGAAGAGACATGAGATGGTAGCTAAACATTTAGTTATGTTTTATTATTTTGCCCAACACCTTTGGCCAGAGCAGAACATAAGAGATTCTTTCCAGAAAGTGACCCTAAGAAGATATAGAAAATGTGGATATGAGAATTTACAGTTAAGAAAAGGCTGTAAAAGTGTGGTTGAGTGTAAACAGCACAAAGGAGATTATAGTGGACTTAACCAATGTTTGAAAACTACCTTGAGCAAAATATTTCAATGTAATAAATATGTAGAAGTTTTCCATAAAATTTCAAATTCAAATAGACACAAGATGAGACATACTGAAAATAAACATTTTAAATGTAAAGAATGTCGCAAAACATTTTGCATGCTTTCACACCTAACTCAACATAAAAGAATCCAAACTAGAGTGAATTTCTACAAATGTGAAGCATATGGAAGAGCCTTTAACTGGTCCTCAACCCTTAATAAACATAAGAGAATTCATACTGGAGAAAAACCTTACAAATGTAAAGAATGTGGCAAAGCCTTTAACCAGACCTCACACCTTATTAGACATAAGAGAATTCATACTGAAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCAGTCATCGACCCTTACTACACATAATATAATTCATACTGGGGAAATTCCCTACAAATGTGAGAAATGTGTTAGAGCTTTTAACCAAGCCTCAAAGCTTACTGAACATAAGTTAATTCATACCGGAGAGAAACGTTATGAATGTGAAGAATGCGGCAAAGCTTTTAACCGATCCTCAAAACTTACTGAACATAAGTACATTCATACTGGAGAGAAGCTGTACAAATGTGAAGAATGTGGTAAAGCCTTTAACCAGTCCTCAACCCTTACTACACATAAGAGAATTCATAGTGGAGAGAAGCCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAAACAATTTTCAAATCTTACTGACCATAAAAAAATTCATACTGGAGAGAAACCCTACAAATGTGAGGAATGTGGCAAAGCTTTTAACCAACTCTCAAACCTTACTAGACATAAGGTAATTCATACTGGAGAGAAACCCTACAAATGTGGAGAATGTGGCAAAGCCTTTAACCAGTCCTCAGCCCTTAATACACATAAGATAATCCATACTGGAGAGAATCCCCACAAATGTAGAGAATCTGGCAAAGTTTTCCACCTATCCTCAAAACTTAGTACATGTAAGAAAATTCATACTGGAGAGAAACTCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCGATCTTCAACCCTTATTGGACATAAGAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACCAATCTTCAACACTTACTACACATAAGATAATTCATACTGAAGAGAAACAGTACAAATGTGATGAATGTGGCAAAGCTTCTACCTGATCCTCAAAACTCATTGAACACAAGAAAATTCATACTGGAGAGAAACCTTACAAGTGTGAAGAATGTGGCAAAACTTCTAACCATTTCTCAACCCTTACTAAACATAAGATGATTCATACTGGAGAGAAGTTACACAAATGTGATGAATGTGACAAAGCTTTTAACCAATCTTCAACCCTTTCTACACATAAAAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAGAGCTTTTAATTGATCATCAAACCTTATTAAACATAAGAAAATTCATATTGGAGAGAAACCCTACAAATGTGAAGAATGTGGAAAAGCTTTTAACCAGTTCTCAACTCTTACTACACATAAAATAATTCATACTGGAGAGAAACCATATAAATGTGAAGAATGTGGCAAAGCTTTCAACCTATACGTAAACCTTACTACACATAAGAAAATTCATACTGGAGAGAAACCCTACAAGTGTGAAGAATGTGGCAAAGCTTTTAGCCAAGTGTCAACTCTTACTATACATAAAAGAATTCATACTGGAGAGAAACCCTACAAGTGTGAAGAATGTGGCAAAGCTTTTAACCAAGTGTCAACTCTTACTATACATAAAAGAATTCATACTGGAGAGAAACCTTACAAATGTGAGGAATGTGGCAAAACTTTCAGTCGATGCTCAAAACTTACTACACATAAGAAAATTCATACAGGAGAGAAACCTTACAAATGTGAAAAATGTGCTAAAGCTTTTAGCCAGTCTTCAACCCTTTCTACATATAAGATAATTCACACTGGAGAGAAATGCTACAAATGTGAAGAATGTGGCAAAGTTTTTAACCGATCTTCAAACCTTACAGACCATAAAAAAATTCATACAGGAGAGAAATCCTACAAATGTGAAGAATGTGACAAGGCCTTTAACCTGTCCTCAACGCTTACTAAACATAAGGTAATTCATACTGGAGAGAAACTGTACAAATGTAAAGAATGTGGTAAAGCTTTTAAACAGTTCTCACACCTTGCTATACATAATATAATTCATACTGGAGAGAAACTCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACTTATCCTCAAACCTTACTGCACATAAGAAAAATCGTACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTAACCTATCATCAACCCTTACTCCACATAAGACAATTCATATTTGAGAGAAACCCTGCAAATGTGAAGAATGTGGCAATGCTTGTAACTAAATCTCAAACTTTACTAAACATAAGAAAATTAATACTGGAAACTTTACAAACCTGAAAGATGTGACAATGATTTTGACAACACCTTCAAACTTTTCTAAACATAAAATAAATCATACTGGTGAGAAATCTTAAAAATATGAAGAATGGTACAAAGCCTTTAAATGGTTGTCACACTTGATTGTAGGTAAGATAATTTATACTGGAGGAAACTCCCAGAAGTGTGAAGAATGTGGCAAAACTTTTAATTTTTCACACCTTATAGCACAGGAAAGCACTTCAGAAAAATTGTACAAATATAAATGTGGAAAAGCCATTAATATCTGCTTACATCTTACTCAACATTAGAGAGTTAGTGCTTAATAAAAGCATTATAAAAGCAATTAGTGTAAAATCAGAAAATGAAAGttttttttttttttttagatggagtcttgctctgtcacccaggctggagtgcagtggtgtgatcttggctcactgcaacctctgcctcccaggttcaagcaattctcctgccttagcctccagagtagctgagactacaggcacacaccaccacatttggctaatttttttatttttagtagagactggctatcaccatgttggccaggctgatcttgaactcctgacctcaagtgatccacatgcctctgcctcccaaagtgctgggattataggtgtgagtcactgtgcctgacAAATATAAGCCTTTAAAGAGAAGAAGGTTTTCATTTTGAAGACAAACATTAGGTACATAAAGAGGGTTGTAGTGTCTTTATTTGTATCACAGATTTTATTGTACACATTATGTACTAAAGGAAAATCCTGAAGCAGTGCTCAAACTTTGATCAACATCAGGGAGTTTATATTGGAGAAAAACTGCAAATGTAATATATTTGGAAAAACATTTTTCAAAAACTACTGCTTAGAAAACACCAGGGGATTTATACTAAAATATATTTTTGCAGATGCAGTAAGTATAAAAGAAATTTAATCCAAAATTAAGTGTGTGTAAATATCAGAGAATTCACAGTAGAAATATCTAAGGCACTGACATTTTAGACATTGAACTAATCAGTGTGCTGAGTACAGAAAATAATCCAAAATTAAAGTTGGTAGATAAATTATTTATATATAACTTTAAAAGAGGTAGAAATATTTTTAGTTATAATTACATTTAAAGTATACTTTTTTCTTTGAAAAAATTACAAAATTTTTAAAAAGTGAATGATGTAATTCAACTCAAATTACTTCATGCTTTTCATTCTATTGTATTCACATGTGAAAGCATGTGATCAATTGCTGCTTCATCAAAGATATGAGACATTCTTTTTTGTTAGGTGGGCAATATTTTTTACCTTTTCTATGGAAGAGTAAAGACATTACAATGTAGGATGCATGATAAAAATCTAAGTGGAGAGGCTCTTTGTGTTTAATTTATAATATTGAATGATGTATGAGGGAAGTGTTCAGAGGAATATTCTGCATTCTAGTGAAAATATCTTTTATTTTAGTTAAAATTAAATTAAAATTAGTAGTATATCATTTTACTAACTGTACTTTTATGTAATAAAATGCAGCACATTTAAAAAATTTTAGATTATTGTGAACTTAATTTTTTAATTAAACTTTTTTTTTAACATGTTAAGACCAATTGTGCATTCAGTGAAGTATTATCATGCCACTAACTTCAACCTATCCCACCTTACTCAAGGGTGTTGGTAAAAGATAGTAACAATGTACTATTTAATAACAGAGTGGACTAACATCTCTAATAATTTCTCTTGCCAGTGACTTTAAACTAAAGAACTTAATTAAAGAACATTGTTCCCATAGGTTAAATTTTTATTCTTTTTCTTATTTAAACATATTTttcttaacttttgtgggtacatagtgtgtgtatatatttatgccatatatggcatattttgatacaggcatatgaataggtattaatcacatcagggcaaatgaaatatccatcaactccagcatttatcatttgtattacaaaccgattctacacttttagttactttaaaatgtacaagtaaattgctattgactatagGGTCATTTTCATGGGTATAATAAAAATTATATACAAGTATAAATAAAATCCTGAGTCTTAAAATTCTGAGTCCTGCTTAAACATTTTAAAAATTTTGTTATGTATTTTTCTTTGAACATGTCTCTCTGCCTGCAAACATAACAGAATTTTAGTATTGGTTTACATAGAGTTAACTATACCCATATATTACTCTAAAAATAAATGTTAAGTGCAAGAAAGTTATGGACTGTTTTTGTGTGAGTGTGAGTTTGTACCTATTTTCAAAAGAAAAGAGCAATATTGGAGCAAAACAAATATTTTAATAAAGTAATGTACTAGACAACTGAAAACTTCAAAAATGCTGAAAGTAAATGTATACTCTGCTTTGTATTGAATTCATTACTGCCAAATCTTCTGACTTATGATTCAGAATCTCTCCATGCAAATTATGTTTTTACTTGCCTGTTAGTCATGCTAGACCTATAATTTTCTTGTTTCTTACCATTTTTTTCTTTTATACTTTATGAGGTATTATGTGAGCTGTTCATGGATTATAAGAATGATTTTTATAAAATTCAGTACTGCACACAAGATAAGTTTTAGATGTATTTCCAAAATTGTGTATTAATTATATTTAGTTAGAACATTCCATTTGTTCTTTTAATTGGAGAATCCTATATAAGCCTATATTTCTTATTCTTTTCTCTTGTTATAATTGACATAAGTAAATTTATTTATTTATTGAGCCAATTTGTTCAGGTAAGAACTAGGAATGCTTCATAAGTCATGAGGATGTTTTTATATATATATGTGGCAAACAAATATGACAGTGCTTGCTGTGTAACAGATGTTCCATAATAACCTGTAAACATTCCTGCTGGAGTTAGTTTGTAACTTCAAGTCAGAGATGGAAAATACCAATAGTGAAGAAATAACATTGATTCTTCATGTGCAGATAACATTTTTTTTCCATGCTGCAAAGCTAAATTTTGCTGAATTTAAAAAGAAATTTTGGTTCTTTTATTTCCTAATTACCTTTAGTTTTGTTTGTCTTATTATGTGACTTCTGTGTATTCATCACAGCCCTTCTCCTTCTTTTTCTATGTGATGGCTACACTTTGCTCACTGTTGTCTTCATGCCATGTCATTTTATACAGTACTTTGTAGGTTTTGATGAGAAAGTTGGTATTTTTAATGCACTCAAAAATTGCTTTTTATTGGAGAGTACTTATCAATATAACTTTCTGATCAGTTAATTAAGATAAAAGGCATACATTGTCCACAGGTGAGAGGATTAAATCAGTTAGCATTATTTTTTTCTGTTTGTAAAAGGAAAAACTTATTAAATTTTTAAACGGAGTTATTaaacagagtttcactcttattgcccaggctggagtgcaAATATATTGTGGCAAATATAAAATTTGCTAGAAAATACATCTTAGAAATTAAGTTATAAGAGAGCAAATGGTAAGTGAAGAATTTTAAATTTAATTTTCTATGATATAGCATAACATACATTTCCATGCAGAATCTTTTATTTTTAAATGTGAAATTTAAAGGTTGCAAAATAATAAAATGACTTCTGTGGATTTGATATTTGGAATGATATTTCTTTTTTATATTGATATTACAATTCCGAGGAATTTTTCACTCATTATTTTTTTAGTGGGTGAAGGTGAGTGTACAGTTATTGCTTTTTGTCACCTAACTATAGTCAGCTTCTTGGTCATTTTCTCTAGAAAACTTTTGAAGATTATGGCAGCTTTTTGATTAAACATTTTCTGTTATTTTTATGCAAATTCATTTATTGTGTTCACAGGGTGGCCAGTCATGAGACCATAAGCAACAGCTGCCCTTTTAGTGTCTTTCATGCCATTACCATCTGtaataaataaatgtgtactttattctgcaaaacatgatgtttggaagtatatgttgtcaaatgcttaattctaggtaattaaggctttacctcacatcgttaacatttttgtggtcagagtatgtgacattgtcaatgtttttcaaaaacacaactacattattatgatctgtagtcactatgctgtacaaaaagatctcttaaacttattcctcctattaaactataattatgtattctttgaccaacatcttccaaaaccccccttttttctaaataccttggtgtctggtggtcaccactttactctctactttaatgggattaagtttcttagaatccctgtgtaagtaaaatcatgaaaaataatctttgtgtctggctcatgtagacaaatatgatgtcctccaggttaattcatgtgattgaaaataatagaaatttcttttttaaagacgaagagtattccattgtgtatatgtaccacattgtctttatttactcataaatgttgaactgttgattgtgtattttggtaattgtgaagagtgttgcaaacaacatagaagcataaatgtttcttcattctgatttcacttgttttggatatatacagtaaaattgctgtattgtggtttaattttaaattttttgacaaatttttgtttttcatagtgactctcctcattcacattcaaaccaacagtgtgcaagcattccttttcttcatactttgactaacactttcttttctttttagtaagagtaattctaacaggagtgagttgataatctcctggtttttctttttgctttcctgattatagttgatattgagcattttttatatatcttgaccatttgtcttttcttgaaaaatatttaagccttttgctcatttttaatagttatttgtcttctgttgtatagtcatttaagttgtttatatgtttctgttattaaccctttgtcccacgtatgatttgcaaatattttctcccatttttttcagttgtctcattttgttgattgtatcagattccatgaagcagctttttaatttcaagtaatctaacgtatctatttttcttttgatttccttggattttgaggttaaataataaaagtcacagcctaga

>NM_001348050.2 

GTCCAATCAGGCACTCAGCTGGAGCAGACAGGACGGCTTCCGGGTTTGGTGGGGCCTTTGTCTCTGGCGGCAGCCGGAGCTTCTGGTGTAGTCTTCACTGCTCTGTGTCTTCTGCTCCTAGAGGCCCAGCTTCTGTGGCCTCGTTACCTGCAGGTATTGGGAGATCCACAGCTAAGACGCCAGGACCCACTGGAAGCCTAGAAATGGGACCATTGACATTTATGGATGTGGCCATAGAATTCTCTTTGGAGGAGTGGCAATGCCTGGACACTGCACAGCAGAATTTATATAGGCATGTGATGTGAGAGAACTACAGAAACCTGGTTTTCTTGGGTGAAGGTATTGCTGTCTCTAAGCCAGACCTGATTACCTGTCTGGAGCAAGGAAAAGAGCCCTGGAATATGAAGAGACATGAGATGGTAGCTAAACATTTAGTTATGTTTTATTATTTTGCCCAACACCTTTGGCCAGAGCAGAACATAAGAGATTCTTTCCAGAAAGTGACCCTAAGAAGATATAGAAAATGTGGATATGAGAATTTACAGTTAAGAAAAGGCTGTAAAAGTGTGGTTGAGTGTAAACAGCACAAAGGAGATTATAGTGGACTTAACCAATGTTTGAAAACTACCTTGAGCAAAATATTTCAATGTAATAAATATGTAGAAGTTTTCCATAAAATTTCAAATTCAAATAGACACAAGATGAGACATACTGAAAATAAACATTTTAAATGTAAAGAATGTCGCAAAACATTTTGCATGCTTTCACACCTAACTCAACATAAAAGAATCCAAACTAGAGTGAATTTCTACAAATGTGAAGCATATGGAAGAGCCTTTAACTGGTCCTCAACCCTTAATAAACATAAGAGAATTCATACTGGAGAAAAACCTTACAAATGTAAAGAATGTGGCAAAGCCTTTAACCAGACCTCACACCTTATTAGACATAAGAGAATTCATACTGAAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCAGTCATCGACCCTTACTACACATAATATAATTCATACTGGGGAAATTCCCTACAAATGTGAGAAATGTGTTAGAGCTTTTAACCAAGCCTCAAAGCTTACTGAACATAAGTTAATTCATACCGGAGAGAAACGTTATGAATGTGAAGAATGCGGCAAAGCTTTTAACCGATCCTCAAAACTTACTGAACATAAGTACATTCATACTGGAGAGAAGCTGTACAAATGTGAAGAATGTGGTAAAGCCTTTAACCAGTCCTCAACCCTTACTACACATAAGAGAATTCATAGTGGAGAGAAGCCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAAACAATTTTCAAATCTTACTGACCATAAAAAAATTCATACTGGAGAGAAACCCTACAAATGTGAGGAATGTGGCAAAGCTTTTAACCAACTCTCAAACCTTACTAGACATAAGGTAATTCATACTGGAGAGAAACCCTACAAATGTGGAGAATGTGGCAAAGCCTTTAACCAGTCCTCAGCCCTTAATACACATAAGATAATCCATACTGGAGAGAATCCCCACAAATGTAGAGAATCTGGCAAAGTTTTCCACCTATCCTCAAAACTTAGTACATGTAAGAAAATTCATACTGGAGAGAAACTCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCGATCTTCAACCCTTATTGGACATAAGAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACCAATCTTCAACACTTACTACACATAAGATAATTCATACTGAAGAGAAACAGTACAAATGTGATGAATGTGGCAAAGCTTCTACCTGATCCTCAAAACTCATTGAACACAAGAAAATTCATACTGGAGAGAAACCTTACAAGTGTGAAGAATGTGGCAAAACTTCTAACCATTTCTCAACCCTTACTAAACATAAGATGATTCATACTGGAGAGAAGTTACACAAATGTGATGAATGTGACAAAGCTTTTAACCAATCTTCAACCCTTTCTACACATAAAAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAGAGCTTTTAATTGATCATCAAACCTTATTAAACATAAGAAAATTCATATTGGAGAGAAACCCTACAAATGTGAAGAATGTGGAAAAGCTTTTAACCAGTTCTCAACTCTTACTACACATAAAATAATTCATACTGGAGAGAAACCATATAAATGTGAAGAATGTGGCAAAGCTTTCAACCTATACGTAAACCTTACTACACATAAGAAAATTCATACTGGAGAGAAACCCTACAAGTGTGAAGAATGTGGCAAAGCTTTTAGCCAAGTGTCAACTCTTACTATACATAAAAGAATTCATACTGGAGAGAAACCCTACAAGTGTGAAGAATGTGGCAAAGCTTTTAACCAAGTGTCAACTCTTACTATACATAAAAGAATTCATACTGGAGAGAAACCTTACAAATGTGAGGAATGTGGCAAAACTTTCAGTCGATGCTCAAAACTTACTACACATAAGAAAATTCATACAGGAGAGAAACCTTACAAATGTGAAAAATGTGCTAAAGCTTTTAGCCAGTCTTCAACCCTTTCTACATATAAGATAATTCACACTGGAGAGAAATGCTACAAATGTGAAGAATGTGGCAAAGTTTTTAACCGATCTTCAAACCTTACAGACCATAAAAAAATTCATACAGGAGAGAAATCCTACAAATGTGAAGAATGTGACAAGGCCTTTAACCTGTCCTCAACGCTTACTAAACATAAGGTAATTCATACTGGAGAGAAACTGTACAAATGTAAAGAATGTGGTAAAGCTTTTAAACAGTTCTCACACCTTGCTATACATAATATAATTCATACTGGAGAGAAACTCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACTTATCCTCAAACCTTACTGCACATAAGAAAAATCGTACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTAACCTATCATCAACCCTTACTCCACATAAGACAATTCATATTTGAGAGAAACCCTGCAAATGTGAAGAATGTGGCAATGCTTGTAACTAAATCTCAAACTTTACTAAACATAAGAAAATTAATACTGGAAACTTTACAAACCTGAAAGATGTGACAATGATTTTGACAACACCTTCAAACTTTTCTAAACATAAAATAAATCATACTGGTGAGAAATCTTAAAAATATGAAGAATGGTACAAAGCCTTTAAATGGTTGTCACACTTGATTGTAGGTAAGATAATTTATACTGGAGGAAACTCCCAGAAGTGTGAAGAATGTGGCAAAACTTTTAATTTTTCACACCTTATAGCACAGGAAAGCACTTCAGAAAAATTGTACAAATATAAATGTGGAAAAGCCATTAATATCTGCTTACATCTTACTCAACATTAGAGAGTTAGTGCTTAATAAAAGCATTATAAAAGCAATTAGTGTAAAATCAGAAAATGAAAGttttttttttttttttagatggagtcttgctctgtcacccaggctggagtgcagtggtgtgatcttggctcactgcaacctctgcctcccaggttcaagcaattctcctgccttagcctccagagtagctgagactacaggcacacaccaccacatttggctaatttttttatttttagtagagactggctatcaccatgttggccaggctgatcttgaactcctgacctcaagtgatccacatgcctctgcctcccaaagtgctgggattataggtgtgagtcactgtgcctgacAAATATAAGCCTTTAAAGAGAAGAAGGTTTTCATTTTGAAGACAAACATTAGGTACATAAAGAGGGTTGTAGTGTCTTTATTTGTATCACAGATTTTATTGTACACATTATGTACTAAAGGAAAATCCTGAAGCAGTGCTCAAACTTTGATCAACATCAGGGAGTTTATATTGGAGAAAAACTGCAAATGTAATATATTTGGAAAAACATTTTTCAAAAACTACTGCTTAGAAAACACCAGGGGATTTATACTAAAATATATTTTTGCAGATGCAGTAAGTATAAAAGAAATTTAATCCAAAATTAAGTGTGTGTAAATATCAGAGAATTCACAGTAGAAATATCTAAGGCACTGACATTTTAGACATTGAACTAATCAGTGTGCTGAGTACAGAAAATAATCCAAAATTAAAGTTGGTAGATAAATTATTTATATATAACTTTAAAAGAGGTAGAAATATTTTTAGTTATAATTACATTTAAAGTATACTTTTTTCTTTGAAAAAATTACAAAATTTTTAAAAAGTGAATGATGTAATTCAACTCAAATTACTTCATGCTTTTCATTCTATTGTATTCACATGTGAAAGCATGTGATCAATTGCTGCTTCATCAAAGATATGAGACATTCTTTTTTGTTAGGTGGGCAATATTTTTTACCTTTTCTATGGAAGAGTAAAGACATTACAATGTAGGATGCATGATAAAAATCTAAGTGGAGAGGCTCTTTGTGTTTAATTTATAATATTGAATGATGTATGAGGGAAGTGTTCAGAGGAATATTCTGCATTCTAGTGAAAATATCTTTTATTTTAGTTAAAATTAAATTAAAATTAGTAGTATATCATTTTACTAACTGTACTTTTATGTAATAAAATGCAGCACATTTAAAAAATTTTAGATTATTGTGAACTTAATTTTTTAATTAAACTTTTTTTTTAACATGTTAAGACCAATTGTGCATTCAGTGAAGTATTATCATGCCACTAACTTCAACCTATCCCACCTTACTCAAGGGTGTTGGTAAAAGATAGTAACAATGTACTATTTAATAACAGAGTGGACTAACATCTCTAATAATTTCTCTTGCCAGTGACTTTAAACTAAAGAACTTAATTAAAGAACATTGTTCCCATAGGTTAAATTTTTATTCTTTTTCTTATTTAAACATATTTttcttaacttttgtgggtacatagtgtgtgtatatatttatgccatatatggcatattttgatacaggcatatgaataggtattaatcacatcagggcaaatgaaatatccatcaactccagcatttatcatttgtattacaaaccgattctacacttttagttactttaaaatgtacaagtaaattgctattgactatagGGTCATTTTCATGGGTATAATAAAAATTATATACAAGTATAAATAAAATCCTGAGTCTTAAAATTCTGAGTCCTGCTTAAACATTTTAAAAATTTTGTTATGTATTTTTCTTTGAACATGTCTCTCTGCCTGCAAACATAACAGAATTTTAGTATTGGTTTACATAGAGTTAACTATACCCATATATTACTCTAAAAATAAATGTTAAGTGCAAGAAAGTTATGGACTGTTTTTGTGTGAGTGTGAGTTTGTACCTATTTTCAAAAGAAAAGAGCAATATTGGAGCAAAACAAATATTTTAATAAAGTAATGTACTAGACAACTGAAAACTTCAAAAATGCTGAAAGTAAATGTATACTCTGCTTTGTATTGAATTCATTACTGCCAAATCTTCTGACTTATGATTCAGAATCTCTCCATGCAAATTATGTTTTTACTTGCCTGTTAGTCATGCTAGACCTATAATTTTCTTGTTTCTTACCATTTTTTTCTTTTATACTTTATGAGGTATTATGTGAGCTGTTCATGGATTATAAGAATGATTTTTATAAAATTCAGTACTGCACACAAGATAAGTTTTAGATGTATTTCCAAAATTGTGTATTAATTATATTTAGTTAGAACATTCCATTTGTTCTTTTAATTGGAGAATCCTATATAAGCCTATATTTCTTATTCTTTTCTCTTGTTATAATTGACATAAGTAAATTTATTTATTTATTGAGCCAATTTGTTCAGGTAAGAACTAGGAATGCTTCATAAGTCATGAGGATGTTTTTATATATATATGTGGCAAACAAATATGACAGTGCTTGCTGTGTAACAGATGTTCCATAATAACCTGTAAACATTCCTGCTGGAGTTAGTTTGTAACTTCAAGTCAGAGATGGAAAATACCAATAGTGAAGAAATAACATTGATTCTTCATGTGCAGATAACATTTTTTTTCCATGCTGCAAAGCTAAATTTTGCTGAATTTAAAAAGAAATTTTGGTTCTTTTATTTCCTAATTACCTTTAGTTTTGTTTGTCTTATTATGTGACTTCTGTGTATTCATCACAGCCCTTCTCCTTCTTTTTCTATGTGATGGCTACACTTTGCTCACTGTTGTCTTCATGCCATGTCATTTTATACAGTACTTTGTAGGTTTTGATGAGAAAGTTGGTATTTTTAATGCACTCAAAAATTGCTTTTTATTGGAGAGTACTTATCAATATAACTTTCTGATCAGTTAATTAAGATAAAAGGCATACATTGTCCACAGGTGAGAGGATTAAATCAGTTAGCATTATTTTTTTCTGTTTGTAAAAGGAAAAACTTATTAAATTTTTAAACGGAGTTATTaaacagagtttcactcttattgcccaggctggagtgcaAATATATTGTGGCAAATATAAAATTTGCTAGAAAATACATCTTAGAAATTAAGTTATAAGAGAGCAAATGGTAAGTGAAGAATTTTAAATTTAATTTTCTATGATATAGCATAACATACATTTCCATGCAGAATCTTTTATTTTTAAATGTGAAATTTAAAGGTTGCAAAATAATAAAATGACTTCTGTGGATTTGATATTTGGAATGATATTTCTTTTTTATATTGATATTACAATTCCGAGGAATTTTTCACTCATTATTTTTTTAGTGGGTGAAGGTGAGTGTACAGTTATTGCTTTTTGTCACCTAACTATAGTCAGCTTCTTGGTCATTTTCTCTAGAAAACTTTTGAAGATTATGGCAGCTTTTTGATTAAACATTTTCTGTTATTTTTATGCAAATTCATTTATTGTGTTCACAGGGTGGCCAGTCATGAGACCATAAGCAACAGCTGCCCTTTTAGTGTCTTTCATGCCATTACCATCTGtaataaataaatgtgtactttattctgcaaaacatgatgtttggaagtatatgttgtcaaatgcttaattctaggtaattaaggctttacctcacatcgttaacatttttgtggtcagagtatgtgacattgtcaatgtttttcaaaaacacaactacattattatgatctgtagtcactatgctgtacaaaaagatctcttaaacttattcctcctattaaactataattatgtattctttgaccaacatcttccaaaaccccccttttttctaaataccttggtgtctggtggtcaccactttactctctactttaatgggattaagtttcttagaatccctgtgtaagtaaaatcatgaaaaataatctttgtgtctggctcatgtagacaaatatgatgtcctccaggttaattcatgtgattgaaaataatagaaatttcttttttaaagacgaagagtattccattgtgtatatgtaccacattgtctttatttactcataaatgttgaactgttgattgtgtattttggtaattgtgaagagtgttgcaaacaacatagaagcataaatgtttcttcattctgatttcacttgttttggatatatacagtaaaattgctgtattgtggtttaattttaaattttttgacaaatttttgtttttcatagtgactctcctcattcacattcaaaccaacagtgtgcaagcattccttttcttcatactttgactaacactttcttttctttttagtaagagtaattctaacaggagtgagttgataatctcctggtttttctttttgctttcctgattatagttgatattgagcattttttatatatcttgaccatttgtcttttcttgaaaaatatttaagccttttgctcatttttaatagttatttgtcttctgttgtatagtcatttaagttgtttatatgtttctgttattaaccctttgtcccacgtatgatttgcaaatattttctcccatttttttcagttgtctcattttgttgattgtatcagattccatgaagcagctttttaatttcaagtaatctaacgtatctatttttcttttgatttccttggattttgaggttaaataataaaagtcacagcctaga

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