Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name KLF17P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:62233235-62235596  UCSC
Coordinates (T2T) chr12:62212015-62214376  UCSC
Coordinates (hg19) chr12:62627016-62629377  UCSC
Strand -
Parental Sequence NM_173484.4
Parental seq. overlap 1534 bp
Parental seq. overlap (%) 42.9%
Genomic Region Intragenic (TAFA2)
Retrocopy Summary KLF17P1, located on chr12:62233235-62235596, is a retrocopy of the parental gene KLF17. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name KLF17
Full Name KLF transcription factor 17
Also known as ZLF393|ZNF393|Zfp393
Coordinate chr1:44043927-44135140
Strand +
Gene summary Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gamete generation. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes KLF17P1
Bonobo Pan paniscus KLF17P1
Gorilla Gorilla gorilla KLF17P1
Orangutan Pongo abelii KLF17P1
Gibbon Nomascus leucogenys KLF17P1
Green monkey Chlorocebus sabaeus KLF17P1
Crab-eating macaque Macaca fascicularis KLF17P1
Rhesus Macaca mulatta KLF17P1
Baboon Papio anubis KLF17P1
Golden snub-nosed monkey Rhinopithecus roxellana KLF17P1
Marmoset Callithrix jacchus KLF17P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>KLF17P1
ACTTTGCTGCCTCGGTCTGTGTTACTAGTGGCCCCAGTATACCTGGGATGGACATCCAGGTGCCCTCCATCCAAGCTCCCAAGTGAGGGGAGTGGACATGATTAAAAGAACAGGAGCAGAAGGGGCTCATTTTTGACCCATTCACTAGCCCCAGGGATTGAGGTCTTGGATACTCAAAGAATCTTTCATTTCTACCAGGGCACCAGATCCCTTCCATGGAGCAGGCCATCTCGGGTTCACTGGGCCAGGGCTGGTCTCTGTTCCCCAGCCCACCTGGCTCACACACAGCCTCGTGGGTAGGGTCAGCAGACCAGATTGCTTGTTATGTAAGACGAGAGGTCTGGTTGATGATCTAGCACTTTCACCAAGAAATGGACGTGGAGAGGATCAGAGTGATCAAGAGTGTATGAAGTGCATTCATGTCCCGATAACCACCTGCGATGCCGTGGTGGGTTGCTCCCTGTCTGTTCAGCAGAGAGTCTAGACACCACCTAGTCTTCATGTACAGCCGACCACAGGCTGAGAAGGAGCAGGAAGCTGGGAAGCTGAGCCAGTGGCAGGCGGCGCACCAGGCTGCCCAGGATAAGTAGAACTCAGCACCCATCTTGAACATGACTCATCTTCTGGAAGCTCCGGAGTGCACACCTCTTGGAACCATGGCCTACCAAGCATTCAGCACTTTCCTCACAGGACAGAGATGCCGAGGGCCCCCTTGTTGTCTGTTGAGGCATCAGGGAAGATTGTGGATGAAGGGGGGCCACAGTTCAGTATGCCACTGCCTGAGCATGGCGTGAGCTACTGCCCCTAAGCGACTCCCACTCCTTTCCGGATGATTTACTGTCAGGGAGTGTCTCCCCCTCAGCAAGAGATGATGATTTTCAGTGGGCCCCAGATAATGCCTGTAGGAGAGGCCAGTACTCCAAAGGTGGCCAGGGCCTTCAGGCTGCCAGTCTCAGCTTCCACTGGAATTCCAGTGATGTCTCATATTGGGGACCCTACAATGCCTTACCCTGGCCTCTCGACAGTACCTTCTGATGAAACATTGTTGGCCTCGACCATGCCTTCCACTGAGGCCCAGGCTATGCCCCCTCCGTGGCTCAGATGTTGCCCCCACAAGATGCCCATGATCGTGGGATGCCCCGAGCTGAGTCCCAGTCATTGCTGGTTTTAGGATCTCAGGACTCTCGTAAGTCAGCCAGACTCCCAAGCAGGCCCATTCCTACCGGAGCATCCCAGACCTGCTCCACAGACAGCAGAGCAGAACTCCAGGCCTCAGGAAAGGACTGGTAGACGGGGCTCCTCAGAGGCAAGGCCTTACTGCTGCAACTACGAGAACTGCGGAAAAGCTTATACCAAACGCTCCTACCTTGTTAGCCACCAGTGCAAGCACATGGGTGAGAGGCCCTATTTGTGCAACGGGAAAGGTGTTTATGGTCTTTCTTCCGTTCTAATGAGCGTAGATGACATACGTGGGTACACACCAGACATTGACCATATAAATGTGATCAGTGCAGCCAAGAGTTCATGAGGTCTGACCATCTCAAGCAACACCAGAAGACTCATTGGCCAGGACCCTCAGACCCACGGGCCAACAATGGACAGCAGGACGGTCCTGTTCCTGGTCCTTAGGTGAATGAAGGAAGAGGATTCTAGGCAGAGAACACTGGACCTGGCAACTGCTCAGAGGAGAGGCAGTCTTCAAGTTCTATATTCATTCAGCAAATGTTTTTTGAGCCTACAATACTGAGAGCACCAAGGCTGTGGGGACCCATGGCGAGGAGCATGGAGATAACTAAAGAATGTGTCAGGGAAGAAAGACTTCTCAAGGAGGTGCCTCAGTCAGATCCAAAGGACTCATGGCGGCTAGCTGCACCTCCCATTTCTTGGACATATACCATTGGACATGTCTCTATCTTCTGAAAACTATGGCATGGACAGTAAGGATTCAGAGGTGTATGAAGGCACCCTGCCTCTGCAGAGCAGAAAGATCATAGACAAAATTTCTGAATGTGCCCAGTGCTGCCAAGGAGATAAGCTGGTCCTCTACAGGCTCAAGCTTATCTGGGCCTCTAGAGAAGCCCACAGCCTTGGCTGTGTc
>NM_173484.4
GTGGCGATGTACCGATACCCGCCTGCGACGCCGTGGTGGCTGGTTCCCTGTCTCTTCAGTAGAGAGTCTAGACCCCACCCAGTCTTCATGTACGGCCGACCGCAGGCTGAGATGGAACAGGAGGCTGGGGAGCTGAGCCGGTGGCAGGCGGCGCACCAGGCTGCCCAGGATAACGAGAACTCAGCGCCCATCTTGAACATGTCTTCATCTTCTGGAAGCTCTGGAGTGCACACCTCTTGGAACCAAGGCCTACCAAGCATTCAGCACTTTCCTCACAGCGCAGAGATGCTGGGGTCCCCTTTGGTGTCTGTTGAGGCGCCGGGGCAGAATGTGAATGAAGGGGGGCCACAGTTCAGTATGCCACTGCCTGAGCGTGGTATGAGCTACTGCCCCCAAGCGACTCTCACTCCTTCCCGGATGATTTACTGTCAGAGAATGTCTCCCCCTCAGCAAGAGATGACGATTTTCAGTGGGCCCCAACTAATGCCCGTAGGAGAGCCCAATATTCCAAGGGTAGCCAGGCCCTTCGGTGGGAATCTAAGGATGCCCCCCAATGGGCTGCCAGTCTCGGCTTCCACTGGAATCCCAATAATGTCCCACACTGGGAACCCTCCAGTGCCTTACCCTGGCCTCTCGACAGTACCTTCTGACGAAACATTGTTGGGCCCGACTGTGCCTTCCACTGAGGCCCAGGCAGTGCTCCCCTCCATGGCTCAGATGTTGCCCCCGCAAGATGCCCATGACCTTGGGATGCCCCCAGCTGAGTCCCAGTCATTGCTGGTTTTAGGATCTCAGGACTCTCTTGTCAGTCAGCCAGACTCTCAAGAAGGCCCATTTCTACCAGAGCAGCCCGGACCTGCTCCACAGACAGTAGAGAAGAACTCCAGGCCTCAGGAAGGGACTGGTAGAAGGGGCTCCTCAGAGGCAAGGCCTTACTGCTGCAACTACGAGAACTGCGGAAAAGCTTATACCAAACGCTCCCACCTCGTGAGCCACCAGCGCAAGCACACAGGTGAGAGGCCATATTCTTGCAACTGGGAAAGTTGTTCATGGTCTTTCTTCCGTTCTGATGAGCTTAGACGACATATGCGGGTACACACCAGATATCGACCATATAAATGTGATCAGTGCAGCCGGGAGTTCATGAGGTCTGACCATCTCAAGCAACACCAGAAGACTCATCGGCCGGGACCCTCAGACCCACAGGCCAACAACAACAATGGAGAGCAGGACAGTCCTCCTGCTGCTGGTCCTTAGGTGAATGAAGAAGGAAGAGGATTCCAGGCTGAGAGCACTGGACGTGGCAACTGTTCAGAGGAGAGGCAGTCTTCAAGTTCTACATTCATTCAGAAAAATGTTTTTTGAGCCTACAATACTGAGCGCAACAAGGCTGTGGAGACCCATGGTGAGGAGCATGGAGTTAACTAAAGGATGTGTCAGGGAAGAAAGACTTCTCAAGGAGGTGCCTCCATCAGACCCAAAGGACTCATGGGGGCTAGCTGCACCTCACATTTCTTGGACATATACCGTTGGACATGTCTATCTTCTGGAAACTATGGCATGGACAGTAAGGATTCAGAAGTGCATGAAGGCACCCTGCCTCTGCAGAGCAGAAAGATCATAGACAACATTTATGAATGTGCCCAGTGCTGCCAAGAAGAGAAGCCGGTCCTCTGCAGGCTCAAGCCTATCTGGGCCTCTGGGGAAGCCCCACAGCCTTGGCTGTGCCTGCCCCTGCCCTCTCACCCCTACCCTGACCTTGTCCTACTTCACTGCCTTTGTCTGTGTTACTAGTGGCCCCAGTATACCTGGGATGGACATCCAGGTGCCCTTCATCCAAGCTCCTATGTGAGGGGAATGGACATTATTAAAAGAACAGGGGCAGAAGTGGCTCATTTATGACCCATTCACTAGCCCCAGGGATTGAAGTCTTGGGTACTCAAAGTGTCTTTCTACCAGGGCACCAGATCCCTTCCATGGAGCAGGTCATCTCGGGTTCACTGGGCCAGGGATGGTCTCTGTTCCCCAGCCCACCTGGCTCACACACAGCCTCATGGGTAGGGTCAGCAAACCAGATGGCTTGTTGTTGGAATGTAGGATGAGAGGCCTGCTTGGTGACCTAGCATTTTCACCAAGAAGTGGACGTGGAGAGGACCAGAGTGATCAAGGGTGTATGATGTGCACtacaatggtgggcaaaacaggctcctgctcttgtggaggtcacaatctagcggagaaAGGATGTTACTAGAAGTACACAAATTGggcccggcgcgatggctcacgcctgtaatcccagcacttttggaggccgaggcaggcggatcatttgaggttagagattcgagaccagccgggccaacatggtgaaaccccatctctacaaaaaatacaaaaattagcctggcatatggcgggtaccgtaatcctagctactcgggagactgacgggagaatcgcttgaacccaggaggcggaggttgcagtgagctcagatctcaccattgcactccagcctgggcgactgagcgagactctatctcaaaacaatcaaaacaaaaaaGACctgtggactctagtagattttgaatcctgcctctgccatttcctggctatgaggtgtcttgagaaatttacttgtcactcttgcttcTGATAGTAAAGGGGATGGTGCGATAGATTCAAGATGGAGAGATAAGGTTAAGTGTTTTctttggctgcaacatggagattagattagagcaaggatgtaagggagaggaagggacatagcagtatttcaggtgagagtcaaggtggctttggctagggtgtgagagtggaggtagggagaagtaggaaagtgatagttaactggatttgttaggtgagggtgaggccaagggtgacttccaggttcctgacttgTGTTATAAGTAACACAGAAGAAGAATGGATGAACTTGATTCGTTTTCCATTGATTGTGATATCTATCATACCTGCAAAAAATATTTTGTATATATCCAATTTAATAATAAATGCACTCATGTTAGGAAGGTCaaaaaaaaggaaaaaagaaaaataataaaaaataataaaaaTCCTTaggataacttgaggccaggagtttgagaccagtgtgaccttgtctctgtaaaaaataAAATTAAAAGAAAAA

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