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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CAMTA1P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:64363579-64363996  UCSC
Coordinates (T2T) chr12:64342367-64342784  UCSC
Coordinates (hg19) chr12:64757359-64757776  UCSC
Strand +
Parental Sequence NM_001195563.2
Parental seq. overlap 374 bp
Parental seq. overlap (%) 65.4%
Genomic Region Intragenic (C12orf56)
Retrocopy Summary CAMTA1P1, located on chr12:64363579-64363996, is a retrocopy of the parental gene CAMTA1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CAMTA1
Full Name calmodulin binding transcription activator 1
Also known as CANPMR|CECBA
Coordinate chr1:6785454-7769706
Strand +
Gene summary The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus CAMTA1P1
Gorilla Gorilla gorilla CAMTA1P1
Rhesus Macaca mulatta CAMTA1P1
Golden snub-nosed monkey Rhinopithecus roxellana CAMTA1P2
Chimpanzee Pan troglodytes Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CAMTA1P1
TTGTATTCTTTGGAACCAGCACCTACTATGTTCTCAATGCCGTGCCACCTATAGATGATCATGGGAATAGCCAGAGTAGTCACGTACAAATCTTTTTGCGGAAAAAGGTGCTTGAATGTGTGCCTAAATGTTCGAGTTTAGCACGAGGCCACCATTGGAACACTGATGACAGATCATGATGCGGTCGTCCTTTTGGATCTTTTTAATAATGTGTGACCCTTCACCTTTAATCCCCTGACCTGCATTACCTTGGTAGCCATTTCATTTTTTAATTTCATTTTTTACTTTTGGTGTACAAGCTGTAACATTTCATCTATCAAAGTGTAACATGATGATTTCCTCAAATAGATAACTCCTTTGAGCAATAAATTTGCAAAATGCTGTCTTCGTTTGCTGTATTAAAATTCATTTCCG
>NM_001195563.2
GGCGGCGGGGTGGCTGGGCCGGCGGCGGCGGCGGTACGAGGCGCGCGCTCGGGGTCCCGGTCGCGAGGAGGAGGAGGATGTGGCGCGCGGAGGGGAAATGGCTGCCGAAAACAAGCCGGAAGagcgtttcccaaagtgtattctgcggaacTAGCACCTACTGTGTTCTCAACACCGTGCCACCTATAGAAGATGATCATGGGAACAGCAATAGTAGTCATGTAAAAATCTTTTTACCGAAAAAGCTGCTTGAATGTCTGCCGAAATGTTCAAGTTTACCAAAAGAGAGGCACCGCTGGAACACTAATGAGAGATCATGATGCAGCCGTCCTTTTGGATTTCTTTTTAATAATGTGTGACCCTTCACCTTTGATCCCCTGACCTGCATTACCTTGGTAACCatttcattttttaatttaatttcattttttaatttTGGTGTACAAGCTGTAACATTTCATCTTTCAAAGTGTAACACGCTGATTTCCTCAAATAGAGATACCCCTTTGAGTGATAAATTTGCAAAATGCTGTCTTCATTTTCTGTATTAAAATTCATTTCAGTTTTAAAA

Publications

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