RCPedia: Rtcs

Summary

Retrocopy Name	ZNF347P1	Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr12:67978110-67978431 UCSC
Coordinates (T2T)	chr12:67957699-67958020 UCSC
Coordinates (hg19)	chr12:68371890-68372211 UCSC
Strand	-
Parental Sequence	NM_001172674.2
Parental seq. overlap	257 bp
Parental seq. overlap (%)	3.1%
Genomic Region	Intergenic
Retrocopy Summary	ZNF347P1, located on chr12:67978110-67978431, is a retrocopy of the parental gene ZNF347. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	ZNF347
Full Name	zinc finger protein 347
Also known as	ZNF1111
Coordinate	chr19:53134935-53159053
Strand	-
Gene summary	Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	ZNF160P1
Bonobo	Pan paniscus	ZNF347P1
Gorilla	Gorilla gorilla	ZNF160P1
Orangutan	Pongo abelii	ZNF347P1
Gibbon	Nomascus leucogenys	ZNF160P1
Green monkey	Chlorocebus sabaeus	ZNF841P1
Crab-eating macaque	Macaca fascicularis	ZNF841P1
Rhesus	Macaca mulatta	ZNF841P1
Baboon	Papio anubis	ZNF347P1
Golden snub-nosed monkey	Rhinopithecus roxellana	ZNF347P1
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>ZNF347P1
CAGGAAGAAGCCTAGAAGAGGAGGAAGAGAAAACAAAAGGAGTCAGGGATGACTCCTACTCTGGGACCATTGACATTTAGGGATGTGGCCATAGAATCCTCTTGGGAGAAGTGGCCATGCCTGGAGACTCTACTCAGAGGGGTTTATGCAGAGATGTGATGTTGGAGAACTAAAGGAACTTTATCTTCCTGGGAATCTCTCTTTTTGACCTGGGTAGTATCTCCATGTTGGAGTAAGGGAAAGAGCCTTGGACTGTAGAGAGGCAAGTGCAAATAGCAAGAAACTGAAATGGGTGACAATGGATCAAATGTGTGATCACAGG

>NM_001172674.2
AGTTCCGGAAGCGGATCGTGTTGGGTGCGGGTGACGCCGCCGAGCGTGAGTGTCCCTCAGTATGGATTAAACTTGCGAACCGCCGTGCCCCGTTTCCGCAGCCAGTTCCCGGGCTCGCTACAGACCtttttttttttctttttttttttttttggtgagacggagatttactcttgttgtccaggctggagtgcaatggcgcgatttcggctcaccgcatcctccgcctcccaggttcaagcgattctcctgcctcagcctcccgagtagctgggattacaggcatgtgccaccacgcccggctaattttgtatttttagtagagacggggtttcaccgtgttgcccaggctgatctcgaactcctgacctcagGAAGAACCCTTGAAGAAGAGGAAGAGGAAAGAAAGACAAGTCAGGCATGGCTCTCACCCAGGGACAGGTGACATTCAGGGATGTGGCTATAGAATTCTCTCAGGAGGAGTGGACATGCCTGGACCCCGCTCAGAGGACTTTGTACAGGGACGTGATGTTGGAGAATTATAGGAACCTGGCCTCCCTGGCAGGAATCTCTTGTTTTGACCTCAGTATTATCTCTATGTTGGAGCAAGGGAAGGAGCCTTTCACTTTGGAGAGCCAAGTACAAATAGCAGGAAACCCAGATGGATGGGAATGGATCAAAGCTGTGATCACAGCTCTCTCTTCCGAATTTGTAATGAAAGATTTACTACACAAAGGGAAGAGTAATACAGGAGAAGTATTCCAAACAGTGATGTTGGAAAGACAGGAAAGCCAAGACATTGAAGGATGTTCCTTCAGGGAAGTCCAGAAAAATACACATGGCCTTGAGTATCAATGCAGAGATGCTGAAGGAAATTACAAAGGAGTGCTTTTGACCCAAGAAGGCAATCTCACTCATGGAAGAGATGAACATGATAAAAGAGATGCAAGAAACAAGCTTATTAAAAATCAGCTTGGATTAAGCCTTCAGTCACATCTGCCTGAACTGCAGCTTTTTCAATATGAAGGGAAAATTTATGAATGTAATCAGGTTGAGAAGTCTTTCAACAATAATTCCTCAGTTTCACCACCTCAACAAATGCCTTATAATGTCAAAACCCACATTTCTAAGAAATATCTCAAAGATTTTATCTCTTCTTTATTACTCACACAGGGGCAAAAAGCAAATAATTGGGGAAGCCCTTACAAATCTAATGGATGTGGCATGGTCTTTCCTCAAAATTCACACCTTGCAAGTCATCAGAGAAGTCATACTAAAGAGAAACCTTACAAATGTTATGAGTGTGGCAAAGCCTTTAGAACACGTTCAAACCTAACTACCCATCAGGTGATCCATACTGGCGAAAAACGTTACAAATGTAATGAGTGTGGTAAGGTCTTTAGTCGAAATTCACAACTCTCACAACATCAGAAAATTCACACTGGAGAGAAACCTTATAAATGTAACGAATGTGGCAAGGTCTTCACTCAGAATTCACACCTTGTAAGACATCGAGGAATTCATACTGGAGAGAAACCTTACAAGTGTAATGAGTGTGGGAAAGCCTTTAGAGCTCGTTCAAGCTTAGCTATCCATCAGGCAACCCACAGTGGAGAAAAACCTTACAAATGTAATGAATGTGGCAAGGTCTTCACTCAAAATTCACACCTTACAAATCACTGGAGAATTCACACTGGAGAGAAACCTTACAAGTGTAATGAGTGCGGCAAAGCCTTTGGTGTTCGTTCAAGCCTAGCTATTCATCTGGTAATTCACACCGGAGAAAAGCCTTACAAATGTCATGAATGCGGCAAGGTCTTTAGGCGTAATTCACACCTTGCAAGGCATCAGCTAATTCATACTGGAGAGAAACCTTATAAGTGTAATGAGTGTGGCAAAGCCTTTAGAGCACATTCAAACCTAACTACCCATCAGGTCATCCATACTGGAGAAAAGCCTTACAAATGTAATGAATGTGGCAAGGTCTTCACTCAAAATTCACACCTTGCAAATCATCAAAGAATTCATACTGGAGTGAAGCCTTATATGTGTAATGAGTGCGGCAAAGCCTTCAGTGTGTATTCAAGCCTAACTACCCATCAGGTCATCCATACTGGAGAAAAACCTTACAAATGTAATGAGTGTGGCAAGGTCTTCACTCAGAATTCACACCTTGCAAGACATCGGGGAATTCATACTGGAGAGAAACCTTATAAATGTAATGAATGTGGCAAGGTCTTTAGGCATAATTCATACCTTTCAAGGCATCAGCGAATTCATACTGGAGAGAAACCTTACAAGTATAATGAGTATGGCAAAGCCTTTAGTGAACATTCAAACCTAACTACCCATCAGGTCATCCATACTGGTGAAAAACCTTACAAATGTAATGAGTGTGGCAAGGTCTTCACTCAGAATTCACACCTTGCAAGACATCGGAGAGTTCATACTGGAGGTAAACCTTACCAGTGTAATGAATGTGGCAAAGCCTTTAGTCAAACATCAAAGCTTGCAAGGCATCAGAGAGTTCATACTGGAGAGAAACCATATGAGTGTAATCAGTGTGGGAAAGCCTTTAGTGTCCGTTCAAGCCTAACTACCCATCAGGCAATCCATACTGGAAAAAAACCTTACAAATGCAATGAGTGTGGGAAGGTCTTCACTCAGAATTCACACCTTGCAAGACATCGGGGAATTCATACTGGAGAGAAACCTTACAAGTGTAATGAGTGTGGCAAAGCCTTTAGTCAAACTTCAAAACTTGCAAGGCATCAGAGAATTCATACCGGAGAGAAACCATATGAGTGTGGGAAACCCTTTAGTATCTGTTCAAGCCTAACTACCCATCAGACAATCCATACTGGTGGGAAACCTTACAAATGTAACGTGTGGAAAGTTCTAAAGTCAGAGTTCAAACCTTGCAAGCCATCACAGAATTCATAGTGGAGAGAAACCTTACAAATGAAGGTGGTAACTTTTGCAGTTAGAATTCATTCCTTTGACAACGTCAGAGAATTTATGCCTGAGAGATTCCTTGAAAATGCAATGACTggctgggtgcagtggctcatgcctgtaatcccaacactttgggagtccgaggcaggtggatcacctgaggtcaggagttcaagaccagcctgaccaacatggcgaaaccccatttctactaaaagtacacaattagctaggcctggtggcgtgcgcctgtaatcccagctatataggaggctgaggcaggagaatcacttgaacccaggaggcggaggttgcagtgagccaagatcgtgccaatgcactccatcctgggcaaaaagagcaaaactccatcttaaaggaaaaaaaaaaaaTGCAATGACTGTGGCAAACTCCTCATGAGTTCAAGTATTAATAGACATCCAAGAGTCCATAATAATGAGAAATCACATAAATGTACTGTGTGTGACAGAGGCTTTATTCAGGCCTCACAGCTTTGCAGGCATTAAAATCTACGTATTTGATGGAACCACACAAATGTAATGTGTAAGAGCATCCTGAAGCTCTTACTCTAAGACTGTAACTGTAGGTGAGGATTCATACAAAGAGTGACTCAGTCTCTAGTTCTTTGATTCACTTTTAAAATGATAAACTGCACAATAATTACACGTTCCAATATGGTAAAACTTAAGACATTATATATTTCAAAGGTCAAAGGACATTTGGAAATGGCTACTTACCTTCAGGTTATAAAATCTTTTATTCCATTGTTTGAGGTTTCTCAAAAAGGCTACTGTTTGTGACTTTCAACCTGAACTATGGATCTGTGGCTATTTTGCATCCTTAAGCACCTTTCGTGGTGCCTATCTGGGAAAGAACCACAGTATGGAAAGGCTTACTTCATTACATGAGGATCATTTTTATCCATGTTTATTGAAGAAGGAGGACTCTGCCTTGTAAAATTAAATATTCTCTCAATTGAGAGACCATGGTTTTGGGGCAGAAAATAATGTAAAACTATGATATCAATCATCATACTGATTGTGTTCAGGGTGCTTTTCTGAGAGAAAGACACCATGGGTTTTAGGGAAGTAAGGCTCTACCTGCATTGAGCAGGCCAAGACCTCAGGACACTGGAATTTTTATGAGAGGAGAGTAATAAGTTATTAGTGACTGATTATGTGATGGGAATAGTGCAGGGGAAATGGTTGCCACTTTCTCTACTGAATGGCAATAGCTGTTTTATAGCAGAGATTGATGAAAAATAGGCTTATTTTTGAAATTGAAGAGGTAACAGTTATTAGAGTGGAGAGCTTGGTCAGAAAAACCAGAATACCATGGttttttttgttttgttttgtttttAGTAGAATTCACACTAATTGCTGGAATTACATTTTGCTACAGTTTTATTAAGAATGTGTCACAGACATAATGTTTTGCTAAAAAAAATTCAACGTTTTCTTATAACTATAAACAAATCACATTCTTTGTACCAACATCATTTTATCCTACCTCAGTAGGATACTTCATAGCAGATAATAACAATACACTCAGTCTTTTAGGTTGGAGGATGTAGAACAATTTTTTTTTTCTTTGTGGAATCAACATACAATTTTGGGAAAATGTAATCATACTCTGCACTTGAATTATTCTCTCTACACTCTGCCTTAGAATATTTATATGGATATAATGAAAATCCCATAGAAAGTGCAGTTTTCATACTCTTACACTCTGAAAGCTGCCACAGTGTTGGTGAATATATACCATATTATATTTTTACATGCTTGTGTGCTAAATAACTATGGCATGCATCTTTATTTACATGAAGTGAAAATACAAATATAGAAAGTGTATGggctgggtgtggtggttcatgcctgtaatcctagcactttgagagcccaaggcaggggggtcacttgagtccaggagtttgaaccagccaggacaacatggcaaaaccctgtctctacaaaaaaaatagaaatattacccaggcagggtggctcatgcctgtagtcccagctcctcagggagactgaggcaggtggatcacttgagcctggaggcagaggttgcagtgagccaagatcgcgccattgcactccagcctgggtgacagagcgagaccctgtctcaaaaaaaaCAATTGTATGAAAAATATTggctgggtgtggtggctcacacctgtaatcccagcacttagggaggccaaggcgggtggatcatggggtcagaaaatcgagaccaccctggccaacacagtgaaaccccatctctactaaaaaataccaaatatatatatattggttggatgtggtggcatgcgcctgtaatcccagctactcgggaggctgaggcaggagaatcacttgaacccaggaggtggaggttgcagtgagccgagattgccactgcactccagcctgggcgagaaagtgagactccgtctcaaaaaaaaaaaTTATGAAATTATAAATAGTGCAGAATAACAAAAATAACACTAAGAATGCTATGCTCACATAATTTGACAAGACTAATATTCATGAGTTTCCTCTTAAAAATGAACATATATAATGGAAATTTTGTTTTTGTAGGTAAACTAGAAGTTTCATAAATTTAGCCTTATCATGTTTTTGGTAATGTTAATTTgtcacctctccacaggaagtgtattgaactccatttacagtttggtttagatatggaaaatgaggatgctgaacaatgaagttttagggaaatgtgtattgcataatgaggctttctgtgagaagcaggattgacttcccaaactggtccaaaatggcttgagagagcagggataaataacttgcttggggtgttatggtaataacctttaataaaagggtgggttggggtgaggatcccacacgtgatttgaacttccatctagtgccaaaggagggaacacggacattatcagcttggccagatgggcagaataagaagagggagtgcagaggtataaatggtggtataagacaaaaatcacaaaatggaaactgactGTAGTACAACACTGAATATTTACTCTTGCAACTTCTGATTTCTGGCCAGGCATGGCCAGAAATTACAggctcatgcctgtaatcccagcactttgggagcccgaggcaggtggatcaccttaggtcaggagctcaagacgagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagccaggtgtggtggcgcactcctgtagtcctagctaccagggaggctgaggcaggagaatcacttgaacccgggagacggaggttgcagtgagctgagatctcaccactgcactccagcctgggcaatagagtgagactctcaaaaaaacaaaagaaaTTTCTAACTTCTTTGTTAGGGAAGACCTCCGCTTTCTTCATAATAGTAGATAATACTCTTCCTTTCTGCTGAACCCATAGGGCCCATTACACAACGTCATTCTTGAAAATATTTGTGAAATGCTGTTTAAATTGCCTAAAATATTTTTACAGTAGTTCAATGCAAATGAATTTGTGGAAAAGTTTATTACATAATATGATCAAGCAATTTTAGCCAAAGGGCATTTTTCCAAAGGCTGTGTTATATTCATGTCTTGTTCAGTTTATGGTATTGTGTAACATATTCTCCATAGCTTCTTTTCTTTTTTTttttctttttctttttagacgtggggtctcgctatgttggccaggttggtcttgaactcttggcctcaagcattcctcctgcctcagcttcccaaagtgctaggattacagccatgagccaATAGTAGTAAAATGACTTTTTGTTTTTGTATATGATTTTTACTTTAAGGATTTTTTCCTTCCATACATTTTAATCCAAATTATATGTTTACTGCATTTCTTCTCTGTGTTACTCCAGTGAACACTTAGAAAATACATAAATGAGGGTGTTGTTTAGAAATAAAATTTTGTGACATGAAAATGTATGTAAAACAATGGCAGGTACAGACTAGGTTCTCTGTAAATAGGAAAATGGAGTGTCCTTGTAAATCTTTAGTTCAATTAAAGTACAGGGATACTAGATGGTGAAATGAAGTCTCTTAATATGGAAGTTATCAAAGATCAGATGCTTGAAAATCAAGCGTGTGGAGGTTAACCAGCATCTGGAGAAGTAAATGAAAATACAGTTAATAAGAGAGTCCCCAAGATATTAATTATCATTTATGCAAAGGAGATAATTTCTCTCATTGAATCCCTGGAGGCAATTCAACTTCCTACTGTGGCTGGTATTTCTTTTCTGAGCCAGAGGATCTTACAGCAAAACATGATATTTGTGCAACTTTTGCAATGACAGCTGCCATTTAATATACTCCCCTTAGATTTGTTTCCATTTTAAAAAACTGATATATATTCTTTAATAAGTGATTTATCTTTGCATATATATTTTATATCAATCACATTTAGAGTAAGAATcacagttattaatgctttatgtgtaacaactgaatcatcagctcctgaaataagtattaatgatattctcatttcagaggtgaggaaacttaggacagataagcaaaataaTCAAATTAggctgggcacagtggctcatgcctgtaatcccagcactttgggaggccgaggcggggggatcacctgaggtcaggaattcgagaccagcctgatcaacatggtgaaaccccgtctctactaaaaatacaaaaattagctgggtgtgatggcgggcgcctgtaatcccagctattcgggaggctgaggcaggagaattgcttgagcctgggaggcggatgttgcagttagccgagttcccaccattgcactccagtctcagtgacagagcgggactccAtctctctctctctctctctctctctttctctctctctctctctctctctctctctatatatatatatatatatatatatatatatatatatatatttagaaaatgggtagaactatgaagagacatttcactgaagcagttatactgagataaataggcacataaaaagatttccaacatcaccatccatcaAATCTCAGATCTCAGCATATTCTGCTttaaaagactcatcttgtcacatttcagtaagaggcagaatcgagatttgaatccatgttgtctggttgcaaagacaaagcttttAATGATGATGCTACAGTAACAATGCTAGTTATTTTTGTCCTTTACTCACCATCTATACCTATTTTGTTAGTATCTCTTGTAATTTTTAAATGGTTTATCTTCATATATCATTGTGATTGTGGTAACTTTGTATTAAATCTATATTTTTATAGATCAA

>NM_001172674.2 

AGTTCCGGAAGCGGATCGTGTTGGGTGCGGGTGACGCCGCCGAGCGTGAGTGTCCCTCAGTATGGATTAAACTTGCGAACCGCCGTGCCCCGTTTCCGCAGCCAGTTCCCGGGCTCGCTACAGACCtttttttttttctttttttttttttttggtgagacggagatttactcttgttgtccaggctggagtgcaatggcgcgatttcggctcaccgcatcctccgcctcccaggttcaagcgattctcctgcctcagcctcccgagtagctgggattacaggcatgtgccaccacgcccggctaattttgtatttttagtagagacggggtttcaccgtgttgcccaggctgatctcgaactcctgacctcagGAAGAACCCTTGAAGAAGAGGAAGAGGAAAGAAAGACAAGTCAGGCATGGCTCTCACCCAGGGACAGGTGACATTCAGGGATGTGGCTATAGAATTCTCTCAGGAGGAGTGGACATGCCTGGACCCCGCTCAGAGGACTTTGTACAGGGACGTGATGTTGGAGAATTATAGGAACCTGGCCTCCCTGGCAGGAATCTCTTGTTTTGACCTCAGTATTATCTCTATGTTGGAGCAAGGGAAGGAGCCTTTCACTTTGGAGAGCCAAGTACAAATAGCAGGAAACCCAGATGGATGGGAATGGATCAAAGCTGTGATCACAGCTCTCTCTTCCGAATTTGTAATGAAAGATTTACTACACAAAGGGAAGAGTAATACAGGAGAAGTATTCCAAACAGTGATGTTGGAAAGACAGGAAAGCCAAGACATTGAAGGATGTTCCTTCAGGGAAGTCCAGAAAAATACACATGGCCTTGAGTATCAATGCAGAGATGCTGAAGGAAATTACAAAGGAGTGCTTTTGACCCAAGAAGGCAATCTCACTCATGGAAGAGATGAACATGATAAAAGAGATGCAAGAAACAAGCTTATTAAAAATCAGCTTGGATTAAGCCTTCAGTCACATCTGCCTGAACTGCAGCTTTTTCAATATGAAGGGAAAATTTATGAATGTAATCAGGTTGAGAAGTCTTTCAACAATAATTCCTCAGTTTCACCACCTCAACAAATGCCTTATAATGTCAAAACCCACATTTCTAAGAAATATCTCAAAGATTTTATCTCTTCTTTATTACTCACACAGGGGCAAAAAGCAAATAATTGGGGAAGCCCTTACAAATCTAATGGATGTGGCATGGTCTTTCCTCAAAATTCACACCTTGCAAGTCATCAGAGAAGTCATACTAAAGAGAAACCTTACAAATGTTATGAGTGTGGCAAAGCCTTTAGAACACGTTCAAACCTAACTACCCATCAGGTGATCCATACTGGCGAAAAACGTTACAAATGTAATGAGTGTGGTAAGGTCTTTAGTCGAAATTCACAACTCTCACAACATCAGAAAATTCACACTGGAGAGAAACCTTATAAATGTAACGAATGTGGCAAGGTCTTCACTCAGAATTCACACCTTGTAAGACATCGAGGAATTCATACTGGAGAGAAACCTTACAAGTGTAATGAGTGTGGGAAAGCCTTTAGAGCTCGTTCAAGCTTAGCTATCCATCAGGCAACCCACAGTGGAGAAAAACCTTACAAATGTAATGAATGTGGCAAGGTCTTCACTCAAAATTCACACCTTACAAATCACTGGAGAATTCACACTGGAGAGAAACCTTACAAGTGTAATGAGTGCGGCAAAGCCTTTGGTGTTCGTTCAAGCCTAGCTATTCATCTGGTAATTCACACCGGAGAAAAGCCTTACAAATGTCATGAATGCGGCAAGGTCTTTAGGCGTAATTCACACCTTGCAAGGCATCAGCTAATTCATACTGGAGAGAAACCTTATAAGTGTAATGAGTGTGGCAAAGCCTTTAGAGCACATTCAAACCTAACTACCCATCAGGTCATCCATACTGGAGAAAAGCCTTACAAATGTAATGAATGTGGCAAGGTCTTCACTCAAAATTCACACCTTGCAAATCATCAAAGAATTCATACTGGAGTGAAGCCTTATATGTGTAATGAGTGCGGCAAAGCCTTCAGTGTGTATTCAAGCCTAACTACCCATCAGGTCATCCATACTGGAGAAAAACCTTACAAATGTAATGAGTGTGGCAAGGTCTTCACTCAGAATTCACACCTTGCAAGACATCGGGGAATTCATACTGGAGAGAAACCTTATAAATGTAATGAATGTGGCAAGGTCTTTAGGCATAATTCATACCTTTCAAGGCATCAGCGAATTCATACTGGAGAGAAACCTTACAAGTATAATGAGTATGGCAAAGCCTTTAGTGAACATTCAAACCTAACTACCCATCAGGTCATCCATACTGGTGAAAAACCTTACAAATGTAATGAGTGTGGCAAGGTCTTCACTCAGAATTCACACCTTGCAAGACATCGGAGAGTTCATACTGGAGGTAAACCTTACCAGTGTAATGAATGTGGCAAAGCCTTTAGTCAAACATCAAAGCTTGCAAGGCATCAGAGAGTTCATACTGGAGAGAAACCATATGAGTGTAATCAGTGTGGGAAAGCCTTTAGTGTCCGTTCAAGCCTAACTACCCATCAGGCAATCCATACTGGAAAAAAACCTTACAAATGCAATGAGTGTGGGAAGGTCTTCACTCAGAATTCACACCTTGCAAGACATCGGGGAATTCATACTGGAGAGAAACCTTACAAGTGTAATGAGTGTGGCAAAGCCTTTAGTCAAACTTCAAAACTTGCAAGGCATCAGAGAATTCATACCGGAGAGAAACCATATGAGTGTGGGAAACCCTTTAGTATCTGTTCAAGCCTAACTACCCATCAGACAATCCATACTGGTGGGAAACCTTACAAATGTAACGTGTGGAAAGTTCTAAAGTCAGAGTTCAAACCTTGCAAGCCATCACAGAATTCATAGTGGAGAGAAACCTTACAAATGAAGGTGGTAACTTTTGCAGTTAGAATTCATTCCTTTGACAACGTCAGAGAATTTATGCCTGAGAGATTCCTTGAAAATGCAATGACTggctgggtgcagtggctcatgcctgtaatcccaacactttgggagtccgaggcaggtggatcacctgaggtcaggagttcaagaccagcctgaccaacatggcgaaaccccatttctactaaaagtacacaattagctaggcctggtggcgtgcgcctgtaatcccagctatataggaggctgaggcaggagaatcacttgaacccaggaggcggaggttgcagtgagccaagatcgtgccaatgcactccatcctgggcaaaaagagcaaaactccatcttaaaggaaaaaaaaaaaaTGCAATGACTGTGGCAAACTCCTCATGAGTTCAAGTATTAATAGACATCCAAGAGTCCATAATAATGAGAAATCACATAAATGTACTGTGTGTGACAGAGGCTTTATTCAGGCCTCACAGCTTTGCAGGCATTAAAATCTACGTATTTGATGGAACCACACAAATGTAATGTGTAAGAGCATCCTGAAGCTCTTACTCTAAGACTGTAACTGTAGGTGAGGATTCATACAAAGAGTGACTCAGTCTCTAGTTCTTTGATTCACTTTTAAAATGATAAACTGCACAATAATTACACGTTCCAATATGGTAAAACTTAAGACATTATATATTTCAAAGGTCAAAGGACATTTGGAAATGGCTACTTACCTTCAGGTTATAAAATCTTTTATTCCATTGTTTGAGGTTTCTCAAAAAGGCTACTGTTTGTGACTTTCAACCTGAACTATGGATCTGTGGCTATTTTGCATCCTTAAGCACCTTTCGTGGTGCCTATCTGGGAAAGAACCACAGTATGGAAAGGCTTACTTCATTACATGAGGATCATTTTTATCCATGTTTATTGAAGAAGGAGGACTCTGCCTTGTAAAATTAAATATTCTCTCAATTGAGAGACCATGGTTTTGGGGCAGAAAATAATGTAAAACTATGATATCAATCATCATACTGATTGTGTTCAGGGTGCTTTTCTGAGAGAAAGACACCATGGGTTTTAGGGAAGTAAGGCTCTACCTGCATTGAGCAGGCCAAGACCTCAGGACACTGGAATTTTTATGAGAGGAGAGTAATAAGTTATTAGTGACTGATTATGTGATGGGAATAGTGCAGGGGAAATGGTTGCCACTTTCTCTACTGAATGGCAATAGCTGTTTTATAGCAGAGATTGATGAAAAATAGGCTTATTTTTGAAATTGAAGAGGTAACAGTTATTAGAGTGGAGAGCTTGGTCAGAAAAACCAGAATACCATGGttttttttgttttgttttgtttttAGTAGAATTCACACTAATTGCTGGAATTACATTTTGCTACAGTTTTATTAAGAATGTGTCACAGACATAATGTTTTGCTAAAAAAAATTCAACGTTTTCTTATAACTATAAACAAATCACATTCTTTGTACCAACATCATTTTATCCTACCTCAGTAGGATACTTCATAGCAGATAATAACAATACACTCAGTCTTTTAGGTTGGAGGATGTAGAACAATTTTTTTTTTCTTTGTGGAATCAACATACAATTTTGGGAAAATGTAATCATACTCTGCACTTGAATTATTCTCTCTACACTCTGCCTTAGAATATTTATATGGATATAATGAAAATCCCATAGAAAGTGCAGTTTTCATACTCTTACACTCTGAAAGCTGCCACAGTGTTGGTGAATATATACCATATTATATTTTTACATGCTTGTGTGCTAAATAACTATGGCATGCATCTTTATTTACATGAAGTGAAAATACAAATATAGAAAGTGTATGggctgggtgtggtggttcatgcctgtaatcctagcactttgagagcccaaggcaggggggtcacttgagtccaggagtttgaaccagccaggacaacatggcaaaaccctgtctctacaaaaaaaatagaaatattacccaggcagggtggctcatgcctgtagtcccagctcctcagggagactgaggcaggtggatcacttgagcctggaggcagaggttgcagtgagccaagatcgcgccattgcactccagcctgggtgacagagcgagaccctgtctcaaaaaaaaCAATTGTATGAAAAATATTggctgggtgtggtggctcacacctgtaatcccagcacttagggaggccaaggcgggtggatcatggggtcagaaaatcgagaccaccctggccaacacagtgaaaccccatctctactaaaaaataccaaatatatatatattggttggatgtggtggcatgcgcctgtaatcccagctactcgggaggctgaggcaggagaatcacttgaacccaggaggtggaggttgcagtgagccgagattgccactgcactccagcctgggcgagaaagtgagactccgtctcaaaaaaaaaaaTTATGAAATTATAAATAGTGCAGAATAACAAAAATAACACTAAGAATGCTATGCTCACATAATTTGACAAGACTAATATTCATGAGTTTCCTCTTAAAAATGAACATATATAATGGAAATTTTGTTTTTGTAGGTAAACTAGAAGTTTCATAAATTTAGCCTTATCATGTTTTTGGTAATGTTAATTTgtcacctctccacaggaagtgtattgaactccatttacagtttggtttagatatggaaaatgaggatgctgaacaatgaagttttagggaaatgtgtattgcataatgaggctttctgtgagaagcaggattgacttcccaaactggtccaaaatggcttgagagagcagggataaataacttgcttggggtgttatggtaataacctttaataaaagggtgggttggggtgaggatcccacacgtgatttgaacttccatctagtgccaaaggagggaacacggacattatcagcttggccagatgggcagaataagaagagggagtgcagaggtataaatggtggtataagacaaaaatcacaaaatggaaactgactGTAGTACAACACTGAATATTTACTCTTGCAACTTCTGATTTCTGGCCAGGCATGGCCAGAAATTACAggctcatgcctgtaatcccagcactttgggagcccgaggcaggtggatcaccttaggtcaggagctcaagacgagcctggccaacatggtgaaaccccatctctactaaaaatacaaaaattagccaggtgtggtggcgcactcctgtagtcctagctaccagggaggctgaggcaggagaatcacttgaacccgggagacggaggttgcagtgagctgagatctcaccactgcactccagcctgggcaatagagtgagactctcaaaaaaacaaaagaaaTTTCTAACTTCTTTGTTAGGGAAGACCTCCGCTTTCTTCATAATAGTAGATAATACTCTTCCTTTCTGCTGAACCCATAGGGCCCATTACACAACGTCATTCTTGAAAATATTTGTGAAATGCTGTTTAAATTGCCTAAAATATTTTTACAGTAGTTCAATGCAAATGAATTTGTGGAAAAGTTTATTACATAATATGATCAAGCAATTTTAGCCAAAGGGCATTTTTCCAAAGGCTGTGTTATATTCATGTCTTGTTCAGTTTATGGTATTGTGTAACATATTCTCCATAGCTTCTTTTCTTTTTTTttttctttttctttttagacgtggggtctcgctatgttggccaggttggtcttgaactcttggcctcaagcattcctcctgcctcagcttcccaaagtgctaggattacagccatgagccaATAGTAGTAAAATGACTTTTTGTTTTTGTATATGATTTTTACTTTAAGGATTTTTTCCTTCCATACATTTTAATCCAAATTATATGTTTACTGCATTTCTTCTCTGTGTTACTCCAGTGAACACTTAGAAAATACATAAATGAGGGTGTTGTTTAGAAATAAAATTTTGTGACATGAAAATGTATGTAAAACAATGGCAGGTACAGACTAGGTTCTCTGTAAATAGGAAAATGGAGTGTCCTTGTAAATCTTTAGTTCAATTAAAGTACAGGGATACTAGATGGTGAAATGAAGTCTCTTAATATGGAAGTTATCAAAGATCAGATGCTTGAAAATCAAGCGTGTGGAGGTTAACCAGCATCTGGAGAAGTAAATGAAAATACAGTTAATAAGAGAGTCCCCAAGATATTAATTATCATTTATGCAAAGGAGATAATTTCTCTCATTGAATCCCTGGAGGCAATTCAACTTCCTACTGTGGCTGGTATTTCTTTTCTGAGCCAGAGGATCTTACAGCAAAACATGATATTTGTGCAACTTTTGCAATGACAGCTGCCATTTAATATACTCCCCTTAGATTTGTTTCCATTTTAAAAAACTGATATATATTCTTTAATAAGTGATTTATCTTTGCATATATATTTTATATCAATCACATTTAGAGTAAGAATcacagttattaatgctttatgtgtaacaactgaatcatcagctcctgaaataagtattaatgatattctcatttcagaggtgaggaaacttaggacagataagcaaaataaTCAAATTAggctgggcacagtggctcatgcctgtaatcccagcactttgggaggccgaggcggggggatcacctgaggtcaggaattcgagaccagcctgatcaacatggtgaaaccccgtctctactaaaaatacaaaaattagctgggtgtgatggcgggcgcctgtaatcccagctattcgggaggctgaggcaggagaattgcttgagcctgggaggcggatgttgcagttagccgagttcccaccattgcactccagtctcagtgacagagcgggactccAtctctctctctctctctctctctctttctctctctctctctctctctctctctctatatatatatatatatatatatatatatatatatatatatttagaaaatgggtagaactatgaagagacatttcactgaagcagttatactgagataaataggcacataaaaagatttccaacatcaccatccatcaAATCTCAGATCTCAGCATATTCTGCTttaaaagactcatcttgtcacatttcagtaagaggcagaatcgagatttgaatccatgttgtctggttgcaaagacaaagcttttAATGATGATGCTACAGTAACAATGCTAGTTATTTTTGTCCTTTACTCACCATCTATACCTATTTTGTTAGTATCTCTTGTAATTTTTAAATGGTTTATCTTCATATATCATTGTGATTGTGGTAACTTTGTATTAAATCTATATTTTTATAGATCAA

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