Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GNAT2P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:68913801-68914243  UCSC
Coordinates (T2T) chr12:68893378-68893820  UCSC
Coordinates (hg19) chr12:69307581-69308023  UCSC
Strand +
Parental Sequence NM_001377295.2
Parental seq. overlap 406 bp
Parental seq. overlap (%) 26.7%
Genomic Region Intragenic (CPM)
Retrocopy Summary GNAT2P1, located on chr12:68913801-68914243, is a retrocopy of the parental gene GNAT2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GNAT2
Full Name G protein subunit alpha transducin 2
Also known as ACHM4|GNATC|HG1D
Coordinate chr1:109603091-109619616
Strand -
Gene summary Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes GNAT2P1
Bonobo Pan paniscus GNAT2P1
Gorilla Gorilla gorilla GNAT2P1
Orangutan Pongo abelii GNAT2P1
Gibbon Nomascus leucogenys GNAT2P1
Green monkey Chlorocebus sabaeus GNAT2P1
Crab-eating macaque Macaca fascicularis GNAT2P1
Rhesus Macaca mulatta GNAT2P1
Baboon Papio anubis GNAT2P1
Golden snub-nosed monkey Rhinopithecus roxellana GNAT2P1
Marmoset Callithrix jacchus GNAT2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GNAT2P1
ATCCATCTCAGCATTTGTTTTCCAGAGTATGATGGTAACAACTCCCATGAGGATGCGGGGAATTACATCAAGAGCCAGTTCCTTGACCTCAGTATGCAACAAGATATCAAAAGAATTTACAGTCACATGACCTGTGCTACAGATACACAGAATATCAAATTTGTGTTTGATGCAGCTACACAGATATTATTATCAAAGAAAACCTCAAGGACTGCGGCCTCTTCAAATCCTCACTATTCCATTCCTCAGGTATAAATGCTATAAACAGGCTTGGAATCTGGGTAATTACAAACAGAAAATTATAGTCAGTATACTATGGCCTGAAGAATGAATCCATTCTTTGGAGATGGAGTATGCATGACTGCAACTGTGTTTCACACATTCTTTTCAAAGTGGGATAGCTAGTGCAGCTTAAAGAGCACAAGGCCAGTCATTAGAAGACC
>NM_001377295.2
cctttacacagtgcctggcacgaagtgagggcccagtgaaaggtagctgttatCATTGTCCCAGGATTCATTTTAAGCAGAAGTCCTGCCCCTGCAATCTCACTTGGTCGTCTGTTTTCTTCCGGCCGGCGTAGGAAACCTTACGAGAGAGGATTAGGGGCCTGAAAAAGCTGACAAGACGGCAAATATGGGAAGTGGAGCCAGTGCTGAGGACAAAGAACTGGCCAAGAGGTCCAAGGAGCTAGAAAAGAAGCTGCAGGAGGATGCTGATAAGGAAGCCAAGACTGTCAAGCTGCTACTGCTGGGTGCTGGGGAGTCAGGAAAGAGCACCATCGTCAAACAGATGAAGATCATTCACCAGGATGGCTATTCACCAGAAGAATGCCTGGAGTTCAAGGCTATCATCTATGGAAATGTGCTGCAGTCCATCCTGGCTATCATCCGGGCCATGACCACACTGGGCATCGATTATGCTGAACCAAGCTGTGCGGATGACGGGCGACAGCTCAACAACCTGGCTGACTCCATTGAGGAGGGAACCATGCCTCCTGAGCTCGTGGAGGTCATTAGGAGGTTGTGGAAGGATGGTGGGGTGCAAGCCTGCTTCGAGAGAGCTGCAGAATACCAGCTTAATGACTCCGCATCTTACTACCTGAACCAATTAGAACGAATTACAGACCCTGAGTACCTCCCTAGTGAGCAAGATGTGCTCCGATCCAGAGTCAAAACCACGGGCATCATTGAAACCAAGTTTTCCGTCAAAGACTTGAATTTCAGGATGTTTGATGTGGGAGGGCAGAGATCCGAGAGAAAGAAGTGGATCCACTGCTTCGAGGGAGTCACCTGCATCATTTTCTGTGCAGCCCTCAGTGCCTATGATATGGTGCTGGTGGAAGATGACGAAGTGAATCGTATGCATGAGTCTTTGCATCTGTTCAACAGCATATGTAACCACAAATTCTTTGCGGCTACTTCCATTGTCCTCTTTCTCAACAAGAAGGACCTCTTTGAGGAAAAAATCAAGAAAGTCCATCTCAGCATTTGTTTTCCAGAGTATGATGGTAACAACTCCTATGATGATGCGGGGAATTACATAAAGAGCCAGTTCCTTGACCTCAATATGCGAAAAGATGTCAAAGAAATCTACAGTCACATGACCTGTGCTACAGATACACAGAATGTCAAATTTGTGTTTGATGCAGTTACAGATATTATCATCAAAGAAAACCTCAAGGACTGCGGCCTCTTCTAATCCTCACCATTCCTCAGGTATAAGTTCTATAAACAGGCTTGGAATCTGGGTAATTAAAAACAGAAAATTATAGTCAATATACCATGACATGAAGAATGAATCCATTCTTTGGAGATGGAGTATACATGACTGCAACTGTATTTCATACGTTCTTTTCAAAGTGGGATAGCTATtgcagcttaaagagcacaggccagtagttagaagaccccccaggttccagtactggttttccaacttaatacaaaactgtgaatacttta

Publications

PMID - Link Title