Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CHMP3P1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:71834680-71835393  UCSC
Coordinates (T2T) chr12:71812158-71812871  UCSC
Coordinates (hg19) chr12:72228460-72229173  UCSC
Strand -
Parental Sequence NM_001005753.3
Parental seq. overlap 539 bp
Parental seq. overlap (%) 17.3%
Genomic Region Intergenic
Retrocopy Summary CHMP3P1, located on chr12:71834680-71835393, is a retrocopy of the parental gene RNF103-CHMP3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RNF103-CHMP3
Full Name RNF103-CHMP3 readthrough
Also known as CGI149|CHMP3|NEDF|RNF103-VPS24|VPS24|hVps24
Coordinate chr2:86503430-86721122
Strand -
Gene summary This locus represents naturally occurring read-through transcription between the neighboring RNF103 (ring finger protein 103) and CHMP3 (charged multivesicular body protein 3) genes. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Oct 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHMP3P1
Bonobo Pan paniscus LOC100970314P1
Gorilla Gorilla gorilla LOC101132264P1
Orangutan Pongo abelii CHMP3P1
Gibbon Nomascus leucogenys LOC100586164P1
Green monkey Chlorocebus sabaeus LOC103219923P1
Crab-eating macaque Macaca fascicularis CHMP3P2
Rhesus Macaca mulatta CHMP3P2
Baboon Papio anubis CHMP3P2
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CHMP3P1
AATTACAGCAGGGGCCTTGGGCAAAGCAAAGTGACTGCTGTCCTTCTAGAGCCAGAATCTTCAAGAGCGATGGCCGCCTCAGAGGACAAGGAGGAAGAAGAGGCTCTGGAGCCCATGCAGTCCTGGCTGGTTACACTCTGCAGCTAGGGGCTGCCCAGTGGCCTACCTGCTGGGTGCCCACACACTCCCCTGAAGAGCTGCCATTTTATAAATCTCTTGCATTATACTTCTGTCATGAGGACTTGCATTTTAGAAAAGGTTCTGTTTGTCTCTTTTTACTCTCTGCAGAGATTTTGGGATCACAGAGGGATTGTTCTTACACAGGTGGTGTAATTAAATGCACCATTTTTAGGAGTATAAACAGAAATATCTTACTGTGGGGAAGGCAAAGAAATTCATCTTCTCATGAAGTGCTTCTGAAAATAGAAGTCATTACCTGAATGTTGAAGACGACTTTTTTCTGTAAAACACTATATAAATGAATTTTAATAAACTCTTGTGAAGATTACAGAAGTCCAGGCCACCATGCAGGAGCTGTCCAAAGAAATGTTGAAGGCTGGGATCGTAGAGGAGATGTTAGAGGGCACTTTTGAAAGCATAGAAGATCAGTAAGAAATAGAGAAAGAAGCAGAAATGGAAAGTGACAAAATGCTGTTTGAAATTATATCAGGGg
>NM_001005753.3
CTCCTTTTCCGCGGGCCCCGCCCAGGCGGCTGCCCGTGACCTGCCTGGGCGCGGGGAACTGAAAGCCGGAAGGGGCAAGACGGGTTCAGTTCGTCATGGGGCTGTTTGGAAAGACCCAGGAGAAGCCGCCCAAAGAACTGATATCCAAAGAGAAGAAGAAAAAGTGAAACGATCTGTGAAAGATGCTGCCAAGAAGGGCCAGAAGGATGTCTGCATAGTTCTGGCCAAGGAGATGATCAGGTCAAGGAAGGCTGTGAGCAAGCTGTATGCATCCAAAGCACACATGAACTCAGTGCTCATGGGGATGAAGAACCAGCTCGCGGTCTTGCGAGTGGCTGGTTCCCTGCAGAAGAGCACAGAAGTGATGAAGGCCATGCAAAGTCTTGTGAAGATTCCAGAGATTCAGGCCACCATGAGGGAGTTGTCCAAAGAAATGATGAAGGCTGGGATCATAGAGGAGATGTTAGAGGACACTTTTGAAAGCATGGACGATCAGGAAGAAATGGAGGAAGAAGCAGAAATGGAAATTGACAGAATTCTCTTTGAAATTACAGCAGGGGCCTTGGGCAAAGCACCCAGTAAAGTGACTGATGCCCTTCCAGAGCCAGAACCTCCAGGAGCGATGGCTGCCTCAgaggatgaggaggaggaggaagaggCTCTGGAGGCCATGCAGTCCCGGCTGGCCACACTCCGCAGCTAGGGGCTGCCTACCCCGCTGGGTGTGCACACACTCCTCTCAAGAGCTGCCATTTTATGTGTCTCTTGCACTACACCTCTGTTGTGAGGACTACCATTTTGGAGAAGGTTCTGTTTGTCTCTTTTCATTCTCTGCCCAGGTTTTGGGATCGCAAAGGGATTGTTCTTATAAAAGTGGCATAAATAAATGCATCATTTTTAGGAGTATAGACAGATATATCTTATTGTGGGGAGGGGAAAGAAATCCATCTGCTCATGAAGCACTTCTGAAAATATAGGTGATTGCCTGAATGTCGAAGACTCTACTTTTGTCTATAAAACACTATATAAATGAATTTTAATAAATTTTTGCTTTAGCACTTGGCCCCATTGTAGATTGCCCTGTGCAGTAAACTTTCAAGGTGTCGGCTGCCCCAGATTGCTTCATTTGCTGGGTGTGGAAAGAGTTGCTATGGCCAGGCATATGGGATTTGGAAGCTCAGCAGAAGTGACTTCTGCTCTGTGGTTGCTGCTCCCCGGCTTTCACAGACATGGTATGGCAGCCATTCTTTTATCTATTTAACCAAGAGGATGCTGGGGAATTGTGCTGCTTGTCCTGTTGGCTGGTGGCTGCATTATGTCCTGGGGTGTGCATGTGGGTCTATTTAGAGCTTCTGTCCCTTCCTTCCCATTGCAAGTTGCACCCAGATGAGACAGCTGTAGTACTAGGTCTCTTTCACCTCTCATTGCCTGTCCCTGCTTCGAGCTGGTTGTCTTGTGCGTGGGACATGGGCCTTCCTATCTGTGTTTTCTCAAAGTCAGGAGCTGACCAGGAGCACACTAAGGTGTGGTCATGCATCATAACCAACATTCACTCATCTGGGACATTCTTAAGATACATTTATAAATCATTTCAGCAGTAGTACTTTGTATGTGTTGAGAGTTTACAGAGCTCTTTGACATACGCGATCTTAGTCTTTACAAATAAGGAAAacagctcagtttgggaagtatcagagatgggattcaaacccagatcctctggtccaagttgtatgtgcactgaactaATCAGGCAGGAAAAAAGCCCAGCCACTGTCTCACAGATTGTTTTTTGTATATTGTAGCAAAATCCTGAAACAATGGGGTCCTTCCAGTCTCATCATACAAAATGGCAATCTTggctgggtgcggtggttcatgcctataatcccagtgctttacaaggctgaggcaggaggctctcttgagaataggagttcaagaccagcctgggcaacatagcaagatcctgtctctCCaaaaaaaaaaaaaaaaaaaaaaaaaaaTTTCATTTTTGAGTCCAGAGGACCCTCCTATTACTCTTGATTTCATCTTCAGAGTGTAGTTAAAAAATTAttttaaataattatttttttaaatcagttgtaggttcacagcaaaagtggacaaaaagaaatttctcatatatcccctgccctcacacatgcatagcctcccaccactatcagtatcccacaccagagtggtacatttgttacaatcaataaacctccattgacacatcattatcacccaaagtccatagtttacatgaagattcactctggtgttgtacattgtatgggcttagacaaatgtatgatgatatctacaattatagaatcatacagaatagtttcactgccctaaaacttctctatgcttcacctgttcatccctttcttccctaatcccctggcaaccactTTAAAAAAAAAAttaggttcagggggtacatgtgcaggtaaactcgtgacaagggggtttgttatacagattatttagtgacccaggtactaagcctagtacccaatagttacttttctggtcctgtcccttttcccaccctccaccctcaggtaggccccagtatgttattcctttgtgtccatgttatttcactcccacttgtgagaacatggaatatttggtttcctgttcctatgttagtttgttaaggataatggcctccagccccatccatgttcctgcaaaggacatgatctttctttggcaaccactttttactgtcgccatagttcttccttttctagaatgtcatattggaatcatatagtatgtagccttttcagactggcttctttcacttaataatatgcaattaaggttcctccatgtcatttcatggcttaatagtgcatttatttttagcactgaataatactccattgtctagatgaatagtttatccattcacctattgaaagacttcttggtggtttccaagttttggcaattatgaataaagctgttgtaaacatctttgtgcaggtttttctatgggcatgtttttaattcatttgaataaataccaagagcttcagtgctggatcata

Publications

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