Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CHMP1AP1
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Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:27686749-27687393  UCSC
Coordinates (T2T) chr1:27528028-27528672  UCSC
Coordinates (hg19) chr1:28013260-28013904  UCSC
Strand -
Parental Sequence NM_002768.5
Parental seq. overlap 544 bp
Parental seq. overlap (%) 23.2%
Genomic Region Intergenic
Retrocopy Summary CHMP1AP1, located on chr1:27686749-27687393, is a retrocopy of the parental gene CHMP1A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CHMP1A
Full Name charged multivesicular body protein 1A
Also known as CHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A
Coordinate chr16:89644435-89657708
Strand -
Gene summary This gene encodes a member of the CHMP/Chmp family of proteins which are involved in multivesicular body sorting of proteins to the interiors of lysosomes. The initial prediction of the protein sequence encoded by this gene suggested that the encoded protein was a metallopeptidase. The nomenclature has been updated recently to reflect the correct biological function of this encoded protein. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CHMP1AP1
Bonobo Pan paniscus CHMP1AP1
Orangutan Pongo abelii CHMP1AP1
Gibbon Nomascus leucogenys CHMP1AP1
Green monkey Chlorocebus sabaeus CHMP1AP1
Crab-eating macaque Macaca fascicularis CHMP1AP1
Rhesus Macaca mulatta CHMP1AP1
Baboon Papio anubis CHMP1AP1
Golden snub-nosed monkey Rhinopithecus roxellana CHMP1AP1
Marmoset Callithrix jacchus CHMP1AP1
Gorilla Gorilla gorilla Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>CHMP1AP1
GGACAATACCCTGTTCCAGTTGAAATTTATGGTGAAGCAGCTGGAGAAACCAGACAAGAAGGCAGAAAAGCACTCCTACGCCAACCAGGCCAAAGTGAAGAAGTCCCTTCAGCAGAAAAATGTAGAGTGCACCCGTGTGTACACCAAGAACACCATCTGCAAGGAGAACAGCAGCGTGAACTGGCTCTACATGGCATCCGCCTGGACACAGTGGCCCCCGAGGTGCAGACAGCTGTGACCATGAAGGTGGTAACCAAGAACATGGTGTAGGTGACCAAAGCCCCAGACAAGGCCTGAACACCACGGACCTGCAGAAGGCCTCTGCAGCGATGGACAGGTTTGAGTAGCAAGTGCAAAACCTGGCCATGCACACATTAGTGATGGAGGATTCCATGAGCTCGGCCGCCACACTGACCATGCCTCAGGAGCAGGTGGACAGACCCATTGTGCAGAGCGCCAAGGAGAATGGCCTGGAGGTCCTAGACCAGCTCAGCCAGTTGCCCAAGGGTGCCTCTGCCGGGCGAGAGCTCCGTGTGAAGCCAGGAGGAACAGCTGTCAAGGGCGTTAGCCGCCCTGAGGAATTAGCCGCACCCTGCCGTGGGCACCGCCTCTGCTCTGTGATGTGCCGCAAGGCTCCTGGCCTCC
>NM_002768.5
GGCGACCCCGGAAGTCCCCGCCGGGTGCAGCTTGGTCGGTTCGATCGCCGCCGGGACCTGACACCGCCCGGAGTTGGCGTCCCTTCTCCCTCTCCGAGTGCTGCTCCTGTCATTGTGGCCATGGACGATACCCTGTTCCAGTTGAAGTTCACGGCGAAGCAGCTGGAGAAGCTGGCCAAGAAGGCGGAGAAGGACTCCAAGGCGGAGCAGGCCAAAGTGAAGAAGGCCCTTCTGCAGAAAAATGTAGAGTGTGCCCGTGTGTATGCCGAGAACGCCATCCGCAAGAAGAACGAAGGTGTGAACTGGCTTCGGATGGCGTCCCGCGTAGACGCAGTGGCCTCCAAGGTGCAGACAGCTGTGACTATGAAGGGGGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGtccccgcccctcttcagtcctgccctcccctcctcagtcctgcccaccccGTGCAGCCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGGCCCATTCACCTTTCTCCTAGAATGCTGTTGTAAATAAACAAATGGATCCCTGGAAA

Publications

PMID - Link Title
No publications available for this retrocopy