Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PRXL2AP1
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:78129681-78131010  UCSC
Coordinates (T2T) chr12:78108048-78109377  UCSC
Coordinates (hg19) chr12:78523461-78524790  UCSC
Strand -
Parental Sequence NM_001243781.2
Parental seq. overlap 1133 bp
Parental seq. overlap (%) 19.5%
Genomic Region Intragenic (NAV3)
Retrocopy Summary PRXL2AP1, located on chr12:78129681-78131010, is a retrocopy of the parental gene PRXL2A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PRXL2A
Full Name peroxiredoxin like 2A
Also known as Adrx|C10orf58|FAM213A|PAMM
Coordinate chr10:80407829-80437115
Strand +
Gene summary Enables antioxidant activity. Involved in regulation of osteoclast differentiation. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM213AP2
Bonobo Pan paniscus PRXL2AP2
Gorilla Gorilla gorilla PRXL2AP2
Gibbon Nomascus leucogenys PRXL2AP1
Green monkey Chlorocebus sabaeus FAM213AP3
Crab-eating macaque Macaca fascicularis FAM213AP3
Rhesus Macaca mulatta PRXL2AP3
Baboon Papio anubis PRXL2AP2
Golden snub-nosed monkey Rhinopithecus roxellana PRXL2AP2
Marmoset Callithrix jacchus PRXL2AP1
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PRXL2AP1
AGGGAGGCACTTGAGGACCCACGGTGCTTCTCTGTGTGGATGTGGTCCATGGGTGCAGGAGCCCTTGGAGGCTGCTGCCTTGGCACTGATGCTGGCCAACACAGATGTATTTTTGTCCAAGCCCTGGAAAGAGGTGCTGGAGTACCTGGAGAATATAGACCTGAAAACACTGGAGAAGTAACCAATGAGTTTCAAAGCAAAGGAGCTATCGGGAGAAGAATGGAGTTGTGATTGTGTCTGTGCCAGGATGTTTTCTCTGGCAAGAGGGGCTGCAGATCTGTCCTCCCTGCAACCCAAGTTGGATAAGCTGGGCATCTCCCTCTACGCAGTCATTAAAGAGCAGGTCAGGACTGACATAAAGTTTTTCCAGCCTTGTTTCAAAAGAGAAATCTTCCTGGATGATAATAAAAAGTTCTATGATCTACAAAGACAGAAGATGATGTTTATGGGATTTAGCCCTCTGGGAGTGTGGTACAACTACCTCCAGCCAGGAATCGAGGCTTCCCTGGAAGCCTGGAAAGCCAAGGCTTCATCCTCAGGGGAGTTTTTGTGGTGGGATCAGGAAAGCAGGGGATTCCCGAGCATGCAGAAAAAGAATATGGAGACAAAGTAAACTCACTTTCTGTTCTGGAAGCTGCTAGGAAGATCAAACCAGAGACTTTGGCCTCAGAGAAAAAAATGATCGCATGAAATTGTCCAACTCAGAGAAACTAGGGGCATTCATTCACCTGTGTTCATGGAATGTGTTGTCCCCACTTGTGTCCCTAAGGAGTTAGAAACCTGCATTTATCTTATTCTCAGTATGGCTTATTAACATATTTTAATATTACACTCTGTTTAGGCCCAGTAAGGCAAAATAGTCCCCAAACTAGACTGGCAAAAAGCTAAGAAAGCAGTGAAGATTATTCAGCTAAAACCTGGAAAATACAAGGCTCAAAATTGACTGTTGTGCCTCATTACAAATGTATATGGTGTTTGAGTTCTGTTATTTGAAATTATGTTTATTTTCAGGTCTTCAAAAATCTAAGAGAAGTTGATGATTAACTTGAAGTTTAGAAAATATAAGGTTTTGGATTGTGTGTTTTCTATTACTAATTTTTTATATAATGTCAAAGGAGTACTTTCATGATGGAATTGATGTGCTCTGGGATAGTTTGACAAAGGTAAATTATAAAGTGAAATTTCTTGTTTCATTGTCCTCCGTCCTAAATTCAGAGATGTGTTTTTCTAGAAGGAATGATCGTCTCTGGCTCTAATAAGATTATGTATCAATACTCATCTTTATGTACAAGTTTTTCTGATAAACTAATAATAAAAATATTTACCATAA
>NM_001243781.2
GCCCGCCCCTGGGACCCTCCGGGCCGGGCGGTTTGGCCCCTTAGCGCCCGGGCGTCGGGGCGGTAAAAGGCCGGCAGAAGGGAGGCACTTGAGGACCCAAGTTTCTTCACCATGGGGATGTGGTCCATTGGTGCAGGAGCCCTGGGGGCTGCTGCCTTGGCATTGCTGCTTGCCAACACAGACGTGTTTCTGTCCAAGCCCCAGAAAGCGGCCCTGGAGTACCTGGAGGATATAGACCTGAAAACACTGGAGAAGGAACCAAGGACTTTCAAAGCAAAGGAGCTATGGGAAAAAAATGGAGCTGTGATTATGGCCGTGCGGAGGCCAGGCTGTTTCCTCTGTCGAGAGGAAGCTGCGGATCTGTCCTCCCTGAAAAGCATGTTGGACCAGCTGGGCGTCCCCCTCTATGCAGTGGTAAAGGAGCACATCAGGACTGAAGTGAAGGATTTCCAGCCTTATTTCAAAGGAGAAATCTTCCTGGATGAAAAGAAAAAGTTCTATGGTCCACAAAGGCGGAAGATGATGTTTATGGGATTTATCCGTCTGGGAGTGTGGTACAACTTCTTCCGAGCCTGGAACGGAGGCTTCTCTGGAAACCTGGAAGGAGAAGGCTTCATCCTTGGGGGAGTTTTCGTGGTGGGATCAGGAAAGCAGGGCATTCTTCTTGAGCACCGAGAAAAAGAATTTGGAGACAAAGTAAACCTACTTTCTGTTCTGGAAGCTGCTAAGATGATCAAACCACAGACTTTGGCCTCAGAGAAAAAATGATTGTGTGAAACTGCCCAGCTCAGGGATAACCAGGGACATTCACCTGTGTTCATGGGATGTATTGTTTCCACTCGTGTCCCTAAGGAGTGAGAAACCCATTTATACTCTACTCTCAGTATGGATTATTAATGTATTTTAATATTCTGTTTAGGCCCACTAAGGCAAAATAGCCCCAAAACAAGACTGACAAAAATCTGAAAAACTAATGAGGATTATTAAGCTAAAACCTGGGAAATAGGAGGCTTAAAATTGACTGCCAggctgggtgcagtggctcacacctgtaatcccagcactttgggaggccaaggtgagcaagtcacttgaggtcgggagttcgagaccagcctgagcaacatggcgaaaccccgtctctactaaaaatacaaaaatcacccgggtgtggtggcaggcacctgtagtcccagctacccgggaggctgaggcaggagaatcacttgaacctgggaggtggaggttgcggtgagctgagatcacaccactgtattccagcctgggtgactgagactctaactaaaaaaaaaaaaaaaaaaaaaTTGATTGCTGTGCCTCATTACAAATGCATATGATGTTTGAGTGCTGTTGTTTGAAATTATTTTTCTTTTCGGGTCTTCAAAAATTCAAGAAAAGTTGATGATTGACTTGAAGATTACAAAATTTAAGGTTTTTTGGCATGTGTGTTTTCTATTAATAATTGGTTATATGATGTCAAAGTAATACTTTCATAATAGAATTGACATGCTCTGGGATAGTTTGACAAAGGTAAATTATAAAGTGAAATCTCTTGTTTCATTATCTTCCATTCTAACCTCAGAGATCTGTTTCTCTAGAAAAAATGTCCATCTCTGGCTTTAATAAAATTATGCATCAGAAATCACCTGTATGTATAAGATTTTCTGATAAAACTAATAATTATATTTACCATATAATTGGCTGAAAGTAAAAAAAGTCAGCATTCTCCATGGCTGAGGGGTAAAGTGCCTCGGGGGATTCCTCTGGTTCTAGCTATCTAAGTGGTTTGAAAATGACCAGGAAAAATTCATCCTGTCATTCACGTTAGTAATTTTGCTGTCTTTCCTAGAGGAATGACTTTGGTGTTTAAAATTGGTAGCTGTTTTTCTATTGGTCTTTTAGCCTAATTTGGCAAATCAGAAGAAAGGACATAGAGATGATGAAATATAACTTTATCTTTTTTGTTTGAATTTTGTCGTGTAAGTTTGAGTGACATCATCAAGACCTACCAGGGAGCTCGGCCACAGGGAGTCTACTCAAGGCATCAAACTGGCCCAGGAGTAGAAAGGTGGGGGTGGAAATAGGAAATAGTGTTTACCCAGGGGACTGGCCCAGCCAGGAGGAGAAAGGAATCAGTGTTTACCCAGGAAAGCAAGAATGGATACTGATGTTGGAGGTAAAGCTGGGAAAGTAGGAGAGCATCGGGATTGAGTATGCAGAGTGAGTTAGGGTTGAGTGGTTCGGGACTAAGACCCACTAAGACCATGCCTGCACCTGACTTCATGTAGCAGTGGTTGCATGGGGTATGCATGGGCCCTTAAAGGGCTGGGCTTCTGCAGCATTTGAGGCCATAGCCTTTGGTACTTGCACAGGGTTGGTACCTGTCATCCTTGGGACTCCAGCTACTGATAGGATAACTCAGTACCTAAACTTAGAACTTTAATACCTAAGACACTTGATGGTGAAACAGTTCTCTTGCAACTAAAGAAGAACCTGAggtcaggtgtggtggctcacgcctgtaatcctagcactttgggaagtcgaggtagaaggatcacttgaggtcaggagttcgagaccagcctggccagcatggtgaaaccccatctctactaaaaatacaaaatattagacagacggggtggtacatgcctgtaatcccagctacttgggaggctgaggcaggagaatcgcttgaacccaggaggcagaggttgcagtgagccgagatcgtgccactgcactccagcttgggcaacaagagcgaaactccatatcaaaaaaaaaaaCCTGAGAGGACATTGCACCAATGGAGATGCATCAAGAGAAACATGTTTGGTTTTTTGTGAGCTCTCACCAACTTTTTTCCCCTGGGTCCTCACGTGCAGTGTGGTCTTCTCTTTCTGATTAGCATGTCATTTtggaaagagcactggattgagtcatgaggcataatcaatttctagtttaccagtgtgatcttaagcaaagatctaactcattggcaaaatgggcgtgattccttcccattcagggctgtttatgataagtcactgagggaatgataaatattatgacactgcttctcagactgtaatgtacatgcacatcacataaggaccttattaAAATGGAGACTTAAaaagctggacgctaaaggcaataatgacagattttactcaataactactgcagaaggagagagtcctcagtatagaactgagcttagctccaatctgtgcagaggtgatggaattttaaagaggggagggaggaggttcaaatagaactagggaagtgcaaaattacaaaaagctggtaaggagattggtcaatgtgattcggctatctgtgtctactaactctcaaatttatttatcaaagttaggatcctagcctcccacagagaccaggagtcggccttatcattcctgataattatatgacaaagggatggctcccagaaaaagtgagaaacacattcctgtgcagcagaagatacatatatcccccaaagggacagaaaggatttacaattgtaaattttataaagtatgtcctctaagaagagggagggactgggtgccatggctcatgcctataatcccagcactttgggtggccaaggtgggtgcatcacctgaggtcaggagttcaagagcagcctggccaacatggtgaaaccctgtctctactaaaaatacaaaagttagcctgttgtggtggcgcgcacctgtaatcccagctactcgggtggctgaggcaggagaatcgcttgaacccaggaggcggagggtgcagtgagccgggatcacgccactgcacttcagcctgggtgacagagtgtgactccatctcaagaaaaacgagggagattagaaacctatgatcaggcattggctgaaacaaatggtaaattcttttggcagccttgagcttccccaggcagggacccaaaggggcctgggttatccctgagacagggccttgagctgctagaaactatgctagtgtttgttcaagtctctccgtgtccggggtgagcaaaattgtttgtgctgaaaatcaatgatttgcagctctcaAgattccagtgggcagtctgggtgggcctgagtttctgctttttttttttctttatgtacagggtcttgctctgtcacctaggctagagtgtaattagtggccccagtcatggctcactgcagctgcaaactggctgcaagctgttctggctcagcctaccaagttactgggcttacaggtggatgccaccgtacccaacagattttatttttgtagggatgggggtctccctgtattgcccaggctggtctcaaactcctggcctcccaaagtgtttagattacaggtgtaagccaccacacgtggccagcctctgcatttctaacaggttccaggtgatcttgatgttctgctggtccatgggtcacactttgagaagcatggTTCTAAAGGACTATACAGATTAAAGTCATTAATCTCTGTGGGCTTTGGACTTGAAGTTTCAGCAGCCTTTGACAAGCATTTGCAGGTTTCCTTTTTATTTATTTGATAAACTGAGAATCCACATGCAAAGAAATGCAAGAAAATTCAAAGAACGTAAGAAAATGTCCTTGCTGTAAAGCTGgtggttctcaatctcggatacacagtagaatcacctggtgcgggggttgggggcggggtgcagtgtaaaaattattaaatcagaatctctggggtaggccccaagcaacttttttttttttttttttagatagaatcttgcttgtcacctaggctagagtgcagtaatgcaatcatggctcactgctgccttaacttctgggctcaagtgatatcctcccacctcagcctccctagtagctgggactacaggcgtggactaccacacccaacaaatttttaaattttttgtagaggcaagctcttatactatcttgcacaggctggtctcgaactcctgggctcaagcagtcatcctgcctcagccttccaaagctcagggattacagacatgagccacagcaccaggccaacaatatttcttaaagctcctggagtgattccaatatgcagccaaggttgaaaaccacCCTTTAAAAGGCTCGGCATCCAGTGTGGAAGACCAGCACACTCACGTCAGGAGACCTTACCTGGAGCCAGGATGCCCCTGATCATCTCTGATAactttaaaaggaaggcctcagaagcagccccagaagcaaaagtttctctctgaccttctcctgccctcttgtttctggcttttcattctcccccaaggctacccatagaaactagaatccctcttccccaaggcaggtcatcagaaaccagaaccggttttacccaaagccagccataaaacctaaaaatagtcctctcactccccattcccctttctgtgtaaaaactggttggaaagaaatgatctgacctaccgtgtttgactgtcgtaagatacccattccagagagggtcccaccccgtgcccagaaggaaggaatcctgcacagagaggccaagaagaatctagacagccttgctgggtttcccctctcagtctattactattagatcatacccttcttgtccaatcatatttctacacagtccataatctgttgaacctaaacataaaaatggacaattcccctgtatcttggggtcttcattctgagggctcacatacaattatgatcaaataaatttgtttgctttttctcctgttaa

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