Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RALAP2
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Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:78791653-78794198  UCSC
Coordinates (T2T) chr12:78770488-78773033  UCSC
Coordinates (hg19) chr12:79185433-79187978  UCSC
Strand -
Parental Sequence NM_005402.4
Parental seq. overlap 2317 bp
Parental seq. overlap (%) 82.3%
Genomic Region Intergenic
Retrocopy Summary RALAP2, located on chr12:78791653-78794198, is a retrocopy of the parental gene RALA. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RALA
Full Name RAS like proto-oncogene A
Also known as HINCONS|RAL
Coordinate chr7:39622955-39708124
Strand +
Gene summary The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RALAP2
Bonobo Pan paniscus RALAP2
Gorilla Gorilla gorilla RALAP2
Orangutan Pongo abelii RALAP2
Gibbon Nomascus leucogenys RALAP1
Green monkey Chlorocebus sabaeus RALAP1
Crab-eating macaque Macaca fascicularis RALAP2
Rhesus Macaca mulatta RALAP2
Baboon Papio anubis RALAP2
Golden snub-nosed monkey Rhinopithecus roxellana RALAP2
Marmoset Callithrix jacchus RALAP2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.20.40.6
log10(TPM+1)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>RALAP2
CCGCTGCTTCCGGAGCCCTCGGGGCGGCGGACTGGCTCACGGTGCAGATTCTTCCTAACCTGTTGGTGAGAACTACAACACAAGATGGCCGCAAATAAGCCCAAGGGTCAGAATAATTTGGCCTTACACAAAGTCATCACGGTGGGCAGTGCCGGTGTGGGCAAGGCAGCTCTGACTCTACAGTTCATGTACGATCAAAGAAGGCACCTATCGGAAGAGAGTAGTACTGGATGGCGAGGAAGTACAGATCGGTATCTTAGAAACAGCTGGGCAGGAGGACTATGCTGCAATTAGGGACAACTATTTCCGAAGCAGAGAGGGGTTTCTCTGTGTCTTCTCTATTACAGAAATGGAATCCTTTGCAGCTACAGCTGACTTCAGGGAGCAGATTTTAAGAGTAAAAGAAGATGAGAATGTTCCATTTCTACTGGTTGGTAACAAATCAGATTTAGAAGATAAAAGGCCGGTTTCTGTAAAAGAGGCAAAAAACAGAGCTGACCAGTGGAATGTTAACTATGTGGAAACATCTGCTAAAACACAGCTAATGTTGACAAGGTACTTTTTGATTTAATGAGAGAAATTCGAGCAAAAAAGATGGAAGACAGCAAAGAAAAGAATGGAAAAAAGAAGAGGAAAAGTTCAGCCAAGAGAATCAGAGAAAGGTGCTGCATTTTATAATCAAAGTCCAAATTCCTTTCTTATCTTGACCATACTAATAAATATAATTTATAAGCATTGCCATTGAAGGCTCAATTACTGAAATTACTTTAACATTTTGGAAATTGTTGTATATCACTAAAAGCATGAATTGGAACTGCAATAAAAGTCAAATTTACTTAAAAAAGAAATAAATGTGGCTTTACCAAGAGGCAAAGTTCAACTTATTTCATTATTGCCTACATTTATCATCGTCCTGAATGTAGCATATGAGCTTGCTTTTCTCAGGCAGTCTTTCTTGAAATGTTAAAGAGGTGAGATGGGGGTGGGGAATGGGAGGAAAGGTGACTTTCTCTCGTGTTTTTTTAAATAAAGCTTAAATTTTATATCATTTTAAAATATATTGGTCTTCTACTACCTTGAAAAATGACAATTGTGAACATGATAAACTGTACCACTTTTTTTTAAACCATCGTTATGCAAAATTTAGAAGAAAAAGTTATTGGTATGGTTGTTGCATGTAGTTAAACTGAGAGTAATTCATCTGTGAATCTGATTTAATTACCTGTTGAGTAATTTAGAAAAGTGCTGTAAATGTGTACATGGAAATTTTTGAATATACCTTAATTTAGAAACTGAAAAACACCCAGTTATATCATTCTGGATGTGTTCTTGCTGACACCAGGGTTCCACTGCCCCATGTGTCATGGTGAGAAAATATATGCCCAGCATGGAGTACTGCTTTTGTATAAAAGATCCTTGAGAAGTAACTGGCTGCTAGGACTCTGCCTAAATTTAAAATGTTGGCCATTCTCTGTTTCTTGAAAATATGATTCCAGATCTCTTTGATCGCTTTTAATAAACTGCAAGGTCATTTAAAATGAAGGACCAGCATGTAGTTGTAAGAGAATTTTTGACTGCGAGGATTCAGCACCAGTTTGAATGAACTCTCTTTTTCTCTAAGATGCTGGTCCCTGGAAATCACTTTCTGCCAGTGGAGAACATGTAAGTGTTAAGTTTTTAATCTCCTGGGAGCAGGGCACAGGAAGAAAATGTCAATAATGCTAATGCATTTTGCACTGGAACACTTTGGGAAAATATTCATGCTTGCCATCTGTTCATTTCCAAGTTTGTATTCATGAAGTTACAGTTTTATATAGGAATTATTAGGAGTAAATTTTGTCTGTTTATGTTCATAATGAAGAACACTGTAGCTACATTTTCAGAAGTTAACATCAAGCAGTCAAACCGGGATACAGTGCAGAAAATATGTTTGGCACACACTGACCAAACATTAGGCTGTGTCACCATTGCGTGGTGTCCCTGCTAGAAGAATTCTAGCACGTTATTTGGGGACATAATTTCAGTCGGAAATATGCCACTGTCAGATTTTTTTTTCCTCTTTGCAGTGGGGCTGGGACAGTTGATTGAACAGAGTATTTTTTTCTTTTTGCTTAGTCCTACTTTCAACAGGTCAAAGATATGTTCAGGCGGCAGTCCAGGTAATAGGTGTGTACGTAAATTTAAAAATAGGCTTTTTAGGAACTCGCTTTTTAGATAGGACATCCAGCTTCTCATGTTAAATATTTATCCTTAAAGGATTTGAGATGTACATCTTTCATATTTCTCATAGGCTATGCCATGTGCAGAATTCGTAACCAATGTAACACTGGCCAGTGGGCCTAGCAATCTCCCTGTATACTCGTTATAGTCTTATTTAGCCAGGGGTCCTAACCACTAACATTGTGACTTTGCTTTGAGACCTTTTCTCTCCTGGGTACTGAAGTGCTATGAAGCCAACTGACAAAGATGCATCATGTGTCTTAGGCTGGTGCCACTACCTGATTTGTTTATTTGCAATTTGAGCCATTTAAAAACCAATAAACTTA
>NM_005402.4
GTGGCGGCTGCTGCAGAGCCGCCAGGAGGAGGGTGGATCTCCCCAGAGCAAAGCGTCGGAGtcctcctcctccttctcctcctcctcctcctcctcctccAGCCGCCCAGGCTCCCCCGCCACCCGTCAGACTCCTCCTTCGACCGCTCCCGGCGCGGGGCCTTCCAGGCGACAAGGACCGAGTACCCTCCGGCCGGAGCCACGCAGCCGCGGCTTCCGGAGCCCTCGGGGCGGCGGACTGGCTCGCGGTGCAGATTCTTCTTAATCCTTTGGTGAAAACTGAGACACAAAATGGCTGCAAATAAGCCCAAGGGTCAGAATTCTTTGGCTTTACACAAAGTCATCATGGTGGGCAGTGGTGGCGTGGGCAAGTCAGCTCTGACTCTACAGTTCATGTACGATGAGTTTGTGGAGGACTATGAGCCTACCAAAGCAGACAGCTATCGGAAGAAGGTAGTGCTAGATGGGGAGGAAGTCCAGATCGATATCTTAGATACAGCTGGGCAGGAGGACTACGCTGCAATTAGAGACAACTACTTCCGAAGTGGGGAGGGGTTCCTCTGTGTTTTCTCTATTACAGAAATGGAATCCTTTGCAGCTACAGCTGACTTCAGGGAGCAGATTTTAAGAGTAAAAGAAGATGAGAATGTTCCATTTCTACTGGTTGGTAACAAATCAGATTTAGAAGATAAAAGACAGGTTTCTGTAGAAGAGGCAAAAAACAGAGCTGAGCAGTGGAATGTTAACTACGTGGAAACATCTGCTAAAACACGAGCTAATGTTGACAAGGTATTTTTTGATTTAATGAGAGAAATTCGAGCGAGAAAGATGGAAGACAGCAAAGAAAAGAATGGAAAAAAGAAGAGGAAAAGTTTAGCCAAGAGAATCAGAGAAAGATGCTGCATTTTATAATCAAAGCCCAAACTCCTTTCTTATCTTGACCATACTAATAAATATAATTTATAAGCATTGCCATTGAAGGCTTAATTGACTGAAATTACTTTAACATTTTGGAAATTGTTGTATATCACTAAAAGCATGAATTGGAACTGCAATGAAAGTCAAATTTACTTTAAAAAGAAATTAATATGGCTTCACCAAGAAGCAAAGTTCAACTTATTTCATAATTGCCTACATTTATCATGGTCCTGAATGTAGCGTGTAAGCTTGTGTTTCTTGGGCAGTCTTTCTTGAAATTGAAGAGGTGAAATGGGGGTGGGGAGTGGGAGGAAAGGTGACTTCCTCTGGTGTTTATTATAAAGCTTAAATTTTATATCATTTTAAAATGTCTTGGTCTTCTACTGCCTTGAAAAATGACAATTGTGAACATGATAGTTAAACTACCACTTTTTTTAACCATTATTATGCAAAATTTAGAAGAAAAGTTATTGGCATGGTTGTTGCATATAGTTAAACTGAGAGTAATTCATCTGTGAATCTGCTTTAATTACCTGGTGAGTAACTTAGAAAAGTGGTGTAAACTTGTACATGGAATTTTTTGAATATGCCTTAATTTAGAAACTGAAAAATATCTGGTTATATCATTCTGGGTGTGTTCTTACTGACACCAGGGGTCCGCTGCCCCATGTGTCCTGGTGAGAAAATATATGCCTGGCACAGCTTTTGTATAGAAAATTCTTGAGAAGTAACTGTCCGCTAGAAGTCTGTCCAAATTTAAAATGTGTGCCATATTCTGGTTCTTGAAAATAAGATTCCAGAGCTCTTTGATCGCTTTTAATAAACTGCAAGTTCATTTTAAATGAAGGGCCAGCATATATACTTGCAAGATAATTTTCAGCTGCAAGGATTCAGCACCAGTTATGTTTGAATGAACCCTCCTTTTCTCTGAGATTCTGGTCCCTGGAAATCCCTTTCTGCTAGTGGTGAGCATGTAAGTGTTAAGTTTTTAATCTGGGAGCAGGGCATAGGAAGAAAATGTCAGTAGTGCTAATGCATTTTGCACTAGAACGCTTCGGGAAAATATTCATGCTTGCCATCTGTTCATTTCTAAATTTATATTCATAAAGTTACAGTTTGATACAGGAATTATTAGGAGTAATTCTTTTCTGTTTCTGTTTATAATGAAGAACACTGTAGCTACATTTTCAGAAGTTAACATCAAGCCATCAAACCTGGGTATAGTGCAGAAAACGTGGCACACACTGACCACACATTAGGCTGTGTCACCATTGTGTGGTGTACCTGCTGGAAGAATTCTAGCATGCTACTTGGGGACATAATTTCAGTGGGAAATATGCCACTGACCGATTTTTTTTTTTTCCTCTTTGCAGTGGGGCTAGGACAGTTGATTCAACAAAGTATTTTTTTCTTTTTTCTCAGTCCTAATTTGAACAGGTCAAAGATGTGTTCAGGCATTCCAGGTAACAGGTGTGTATGTAAAGTTAAAAATAGGCTTTTTAGGAACTCACTCTTTAGATATTTACATCCAGCTTCTCATGTTAAATATTTGTCCTTAAAGGGTTTGAGATGTACATCTTTCATTTCGTATTTCTCATAGGCTATGCCATGTGCGGAATTCAAGTTACCAATGTAACACTGGCCAGCGGGCCCAGCAATCTCCATGTGTACTTATTACAGTCTTATTTAACCAGGGGTCCTAACCACTAACATTGTGACTTTGCTTTGAGACCTTTCCTCTCCTGGGTACTGAGGTGCTATGAAGCCAACTGACAAAGATGCATCACGTGTCTTAGGCTGATGCCACTACCCGATTTGTTTATTTGCAATTTGAGCCATTTAAAGACCAATAAACTTCCTTTTTTAAAA

Publications

PMID - Link Title
No publications available for this retrocopy