Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PAFAH1B2P2
Plot displaying the genomic locations of a retrocopy (in chr12) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr12:97731965-97733289  UCSC
Coordinates (T2T) chr12:97705117-97706441  UCSC
Coordinates (hg19) chr12:98125743-98127067  UCSC
Strand -
Parental Sequence NM_002572.4
Parental seq. overlap 1116 bp
Parental seq. overlap (%) 26.6%
Genomic Region Intergenic
Retrocopy Summary PAFAH1B2P2, located on chr12:97731965-97733289, is a retrocopy of the parental gene PAFAH1B2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PAFAH1B2
Full Name platelet activating factor acetylhydrolase 1b catalytic subunit 2
Also known as HEL-S-303
Coordinate chr11:117144287-117176894
Strand +
Gene summary Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2014]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PAFAH1B2P1
Bonobo Pan paniscus PAFAH1B2P1
Gorilla Gorilla gorilla PAFAH1B2P1
Gibbon Nomascus leucogenys PAFAH1B2P1
Green monkey Chlorocebus sabaeus PAFAH1B2P1
Crab-eating macaque Macaca fascicularis PAFAH1B2P1
Rhesus Macaca mulatta PAFAH1B2P1
Baboon Papio anubis PAFAH1B2P1
Golden snub-nosed monkey Rhinopithecus roxellana PAFAH1B2P1
Marmoset Callithrix jacchus PAFAH1B2P1
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PAFAH1B2P2
GGACTCTCTACGTGAGTGTAGAATGAATCAAGCCGACTCAAACACAGCAGCTATTCCACATGCAGTGGAAGATATTCAAGGAGACGACAGATGGATATCTCAGCACAACAGATTTGTCCTGGATGGTAAAGACAAAAAGCCTAACGTTGTGTTTGTGGGAGACCCCATGGTGCAGTTAATGCAGCAACACGAGATATGGCGAGAGCTTTTTTCCCCGTTTCACGCACTGAATTTTAGAACTGAGGAAGATACAAGACATGTTTTATAGAAAATAAAGAGTAGAGAACTGGAGAATATTAAACTTAAGGTCATTGTTCTCTGGGTAAAAACAAACAACCATGAAAATACAGCAGTAGAGTTAGAAGGTAGGATCAAGGCCATCATTCACTCTACCAATTTATCAACATAAGGCAGCCACAAGGCAAAATTCTTGTATTGGATGTGTTACCTTGAGGTGAGAAGCCCAACACTTTGAGGCAAAAGGTGAACCAGCTTCTCAAGGTTTCCTTGCTGAAGCTTGCCCATGTGTAGGTCCTGCATACAGACGGGGGCTTCATGCACCCTGACAGTGCCATCTCCTGCCATGACATATTTGATTCTCTTCATCTTACAGGAGAGGGCTCTGCAAAGATCTGCAGAGCCCTCTATGAACTGATCATGCAGCTGATGGAGGAACACCCAAGGAGAGAAACAAACCACCATTGCCTGACTGGCTCCCATCAGCGTTAATCTCTTCCCAGCTTCCTTGATCAGTTATGCCACTGGCACTACAGAATCCATCTCTTTCTCAAAGCACTTTGCATTGCAAAATGTTCCTGGATGTTCAGCTCTAGTGTTTGAAAGGGTGGAGGGATTTACACTGGCCTTGCACGTAGAAGGTTTATTAGACACAGGAGAAAAAATAGCCTAGGAAGATTGTTGTTTAAATTTATCTGAAACCAGAAGGAGACTTTTTAGTTGTATGTGTGATGCATTTGTTGAATTATCACTGTTTTTCCTAGGACAATATCAAGTCCAAGAACTGACCGATATGAAGTTTTTTTTTCTTGGCCTTGCTTTCTATGGGTTATGTCATATGTAATAATTATCAGAATCACACCTACTTGGCTTAAAAACAGATTTTTATTTTAATTTTTAAAGCTCATAATTTAACCTTTTTTCTTGTTTTGCTTTATTCATATATATCCTCAATATTTTCTTAACATGCAGCAACAGATTGAACATGCTTGCCATTCAAATATGAGAGATGCTATAGTTACAAAGGAATTTGTTCCACTTTCTTAATCCTTCCTATGCATAGCAGTGAAAAACAAATTTTGCCCCAT
>NM_002572.4
GGAGGAGCTGCTGCTGGTGCTGGGGCCGGAGGAGGGACGCGCCGGAGCGGGACCGACGGGACCGAGCGAGCGACCGACGCGCCACCCGCCGACGCCTCAGCCGCTTGGGGCCCGCACGGACCCTCTACTTCAGTGTAGAATGAGCCAAGGAGACTCAAACCCAGCAGCTATTCCGCATGCAGCAGAAGATATTCAAGGAGATGACCGATGGATGTCTCAGCACAACAGATTTGTTTTGGACTGTAAAGACAAAGAGCCTGATGTACTGTTCGTGGGAGACTCCATGGTGCAGTTAATGCAGCAATATGAGATATGGCGAGAGCTTTTTTCCCCACTTCATGCACTGAATTTTGGAATTGGGGGAGATACAACAAGACATGTTTTGTGGAGACTAAAGAATGGAGAACTGGAGAATATTAAGCCTAAGGTCATTGTTGTCTGGGTAGGAACAAATAACCACGAAAATACAGCAGAAGAAGTAGCAGGTGGGATCGAGGCCATTGTACAACTTATCAACACAAGGCAGCCACAGGCCAAAATCATTGTATTGGGTTTGTTACCTCGAGGTGAGAAACCCAATCCTTTGAGGCAAAAGAACGCCAAGGTGAACCAACTCCTCAAGGTTTCGCTGCCGAAGCTTGCCAACGTGCAGCTCCTGGATACCGACGGGGGTTTTGTGCACTCGGACGGTGCCATCTCCTGCCACGACATGTTTGATTTTCTGCATCTGACAGGAGGGGGCTATGCAAAGATCTGCAAACCCCTGCATGAACTGATCATGCAGTTGTTGGAGGAAACACCTGAGGAGAAACAAACCACCATTGCCTGACTGGCTCTTATCAGTGTTAATAGCATCTCAGCTTCCTCAGATCAGTTCTATCACTGGCACTACAGAATCCTTCTCTTTCTTAAGGCACTTTGCATTGTAGAATGTTCCTGGATGTTCATATCTAGTGTTTGAAGGGGAGGAGGGATTTAAACTGGTCCTGTACATAGAAGGTTTGTTTGACAGAGGAGAAAAATTAGCCAAGGAAGATTGTTGTTTAAATTCATTTGAAACCAGAAGGGGACTTTTTAGTTGTATGTGTAACACATTCATTGAATTATTATCACTGTTTTCTTGGGACAACATCAAGCCTAAATACTGAACAATATGAAGATTCTTTTCTTGGCCTTTCTGTGGATTATGTCATATATAATAATTATCAGAATCATTCTACTTGGCTTTAAAACATGTTTTCTCCAATTTTTTTAAGGTTCATAATTTAGCCTTTTGTTTTTATGTTGCTTAGATTCTTATGTATACTGAATATTTTATTAACATGTAGCATCAGGTTGAACATGCTTGTCATTGATATATGGAAGATGCTATAGTTAGAAGTGAATTTGTTCTGCTTTCTTAATCTTTTCCATGCTTAGCAGTGAAAAACAGGTTTTGCCCCAGTAGAGGGATTCTTTGGAGGGTATTATTTTTTATGCTGCTGAATATCATGTCTATAATAGACCCGTGCATGCAGCCTTTCCTCCTTATTCCCCTTCATGCCCCCCTTTCCCCTTCATTCCCCCCGCCACCCCGtttttttttttttttttttttttttGGTTCTTGTTGACATTACAAGCTTTTAACACATTTTTGACCTAGGAGCCCTGTTGCTGGAAGTATAGTCTCCAGCCAGTTACTCTCATGATAGTACTGCTATAAAACTCATTCTTGTGTGGTGTTCTGTGCTATAGATTCTGTGTATTGCTGTTCATATTCGGAGTTCTGGTTTTGTTTTTCCCTTAAAACCTGTTAACAGTTTTTTTTGGGGGTGGGGGGATTCAGAACTCTTGTTTCCCATTCCATAGCACCTGACATTATTTCAAGTTTTATAATATCTTAAGGTGTATATTTTATTTTTTTTATTGGCTTAGttgttttttgttttgttttgtttgagatggagtttcactgttgcccaggctggggtgcaatggtgtgatcttggctcactgcagcctccacctcccgagttcaaatgattctcctgcctcagcttcctgagtagctgggattacaggtgcatgccaccatgcccggctaatttttatatttttattagagacgggatttcgccatgttaaccaggctggtctcgaactcctgacctcaggtgatctgcccgccttggcctcccaaagtgctgggattacaggcatgagccaccgtgcctggccTTATTGGCTTAGTTTTTAAATTATCCTCCAAAAATTTTGGGCCTTTTTCTGTGGGGAAACAAGTGAAGCTGCTCTTCAGCATAGACACTACCTTTATCCCATCATTTTAGTAAAAACTAGGTTTGTTTCACTTCTGAGGTGTCTTATTAATGTACTTCATCTGAGAATTTGTTGATCTTAATGTTCGAGCTATATAAGAACTGCCATTAAAAAAAATGGGATAATAGATGATTTTATCAGTATACCTGTGGAATATGTACAAACTGGATCTATAGATATTTTGAACTGGACCAGGTGGGTATTGAAGTAACCCATCAAAATATGCTCTGCAGTGATTCCGCTTAATGTTTAAATTCAGTAACGTACTTGAAAGGCAAATTTCAGTGCTTTTGTATGTTGGAGGAGGGCTTACTGATGCGTGCTAAGACCGATTTCTGATTGAGGGATGAACCTTGGGCTCATTTTTTTCTTGTGAAGTCTCTTTCTAGAAAATTTTTTGGTTTTGTTCTTTTTAAAAAATACATACTTTTTTGAATGTATCATGTCTTCATTAACAACAGAAAATCCACATGGTGTTTACTAAACTTGTTTACGACATTAAAAATTTCCTTTTTATTTTTAGTAGCCCAGGTTGAGTTTTTCACAAGAGATTTTTTTCTTAGCTGAGGTATAGTTGTATAGCAAGAAGAATTAAGCCAGATTTTTGTGTGTGGAAAGACAGTTTTCTATCCACGTCTTTTTCTGTTTGTCAGAAGGTGGGAGTATGGTCCAAATAAATCCATTAGGTTACTCCTGCAGCATGCGCTTTTAGCTTCTCTCTTGACTGAGGATCAAATATCCCTTTGTGAGCTGGCCCTCAGCTCCTTTGCTCATGTGTACAAACCTCAGATGTTACTACATTTTATATCTACCAGAGCTATTCAAGCAATAGTATTTGAACCACTAGCCTTTTAAATAAAATTCTGCCCCATTACTGATGTGCAGATATTGAGTTCACTTTCATTTTTTGCCAGATTTCTTTGCACTACTTTAGGTAAAAATAGTTAATCTATTTTTCTTTGACATCCTAGTTTGCGTCAGTGACAGAACTTACTGCTTAGTCTTTGTACTTTTTAAAAAATCTATAAATTTAATGCACTGTCCAAGTGAAATGTCCTAGTTGTCATTGTGATTAAGGGGCCAACTTTCCAGGCAGCTAGCAGAGATACTATTCTCTTCCTCTCCCAGCAAATTTGTATTCCTTCGCCCACGCATTCCTGCTATACTAGATGGCAGCCAGTGATGGAACTATAAAGATGTCTGTGGTCATATGTTGAATGTGGCAGCTTGAAGATGTACTGCCACGGGTGATCTAGGGCAGGCTGTCTTCCAGTCCATGTGTTCTCGGTCGCCGTAGACAGCGCTCTGGCTACCACCGTGAGGCTACTTGAACTGTCAGGGGCATCTGCCTAAACCAGAATCTTTTGTCAGAAACCTTAACCCAACAAAACAAATCTTGAGTAGCTCATGCCCGGCTCTTAGGAATTTTGTCTGTTTaaaaaaaaaaaaaaaaaaaaaGTCCAACTTACTTTATTTTATTTTTTTAACCTAGTCACTGTTTACAATTGTATGCTAAAGCCTGAAATATTGTCTGTGCTGTGGTGTATGAGCATTGCCAACTTTATATTTATTGCAGTGAAGAAGAAACTAAAAATATATGGAAATGAGGAGCATGTCCAAGCTCCTAAATCCGTGTGGGTGCATGTGGGAGAAGTGAGTTAGGGCCTCTTGAAAGGAGGCTTTTTGGAGAGGGGTCCCCCAGGTTTCTTGGTGTTCCTGCTTGGGGATCACTGCTGCTAGCTGACTGGACCTCCCCATTGGAAGTTTGTGATTTTGCTTTGGCAAAGTTTCATTGACTAGTAGAACTCATTCTGTTTTAGTGTATATTTCAATATAAATGTAAACATTTTGCTCAA

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