Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name TERF1P5
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:18680494-18683280  UCSC
Coordinates (T2T) chr13:17894382-17897168  UCSC
Coordinates (hg19) chr13:19254634-19257420  UCSC
Strand +
Parental Sequence NM_003218.4
Parental seq. overlap 2115 bp
Parental seq. overlap (%) 64.7%
Genomic Region Intergenic
Retrocopy Summary TERF1P5, located on chr13:18680494-18683280, is a retrocopy of the parental gene TERF1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name TERF1
Full Name telomeric repeat binding factor 1
Also known as PIN2|TRBF1|TRF|TRF1|hTRF1-AS|t-TRF1
Coordinate chr8:73008856-73048123
Strand +
Gene summary This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Multiple transcripts of this gene are alternatively spliced products. [provided by RefSeq, Aug 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes TERF1P4
Bonobo Pan paniscus TERF1P4
Gibbon Nomascus leucogenys TERF1P1
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>TERF1P5
GGCGGATGGTAGGGATGCCGACCCTACCGAGAAGCAGGTGGCAGAAACAGAGAGAAACGATGAGGAGCAGTTCGAATGCCAGGAACGGCTCAAGTGCCAGGTGCAGGTGGGGGCCCCCTGCCGGCTGGATGCTCGATTTCCTCTGCCTCTCTCTTTGCCGAGCTTTCCGCGACGACCGCTCCAAGGACTTCTGCAGGACCCGCAACAGCGCAGAGGCTACTATTCATGGACTATCCAGTCTAACAGCTTACCAGTTGAGAATGATATACGTATGTCAGTTTTTGACAAGAATTGCAGCAGGAAAAACCCTTGATGCACAGTTTGAAAATGATGAACGAATTACACCCTTGGAATCAGCCCTGATGATTTGGGGTTCAATTGAAAAGGAACATGACAAAGTTCAAGAAGAAATACAGAATTTAATTAAAATTCAGGCTATAGCTGTTTGTATGGAAAATGGCAACTTTAAAGAAGCAGAAGAAGTCTTTGAAAGAATATTTGGTGATCCAAATTCTTACATGCCTCTCAAAAGCAAATTGCTTGTGATAATCTCTCAGAAAGATACATTTCATTCCTTTTTTCAACACTTCAGCTACAACCACATGATGGAGAAAATTAAGAGTTATGTGAATTATGTGCTAAGTGAAAAATCATCAACCTTTCTAATGAAGGTAGCAGCAAAAGTAGTAGAAAGTAAAAGAACAAGAACAATAACTTCTCAAGATAAACCTAATGGTAATTATGTTGAAATGGAAACTGAAGCTAATTTGGATACAAGAAAAAGGTCTCACAAGAATCTTTTCTTATCTAAGTTGCAACATGGAACCCAGCAACAAGACCTTAATCAGAAGAGCCACTGAAAGCAGAATAACTGTTTCAAAGAGGCAACCGGTAACTCCTGAAAAACATCGAGCTAGAAAAAGACAGTCATGGCTTTGGGAAGAAGACAGGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTACTGCATTATAAATTCAACAACCGGACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTGCTCAGACAGCGAAGACTGATTGTGTTTCTAAAAGCTTTATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTATTTTAAAACTTCTGTTTAAAGCATTACAGTATTTTTCTGTGACCATCAATTAATATGAGGGTTTGTGCTATAAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGAACTTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAAACCTGTTCCAATGAAAAAATTAAAACCTGTTATGAAAAAAAAAATTCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAATATAACCCATTAAAATGAATAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGGAGATAATGACTTGGTTTATGGCCTTAATATACTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGTGTGACATACTTTTGCTTTCAGTAGTTTCATGTAAAGAAAAAAACTTGAAAATAGATTACTATTAACCTGAGGACCCaAGACAATAGTATTACCCATGGGACAAAATTTGTACTATTAGCAAGAATCATTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCATTGTTTAAACTTTGACAAAAATGGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAAAAGAGTATTCTATAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTAAACAATTTTGGTTTCTCACCAACATTTTATCTAAAAGATTTAGACTAATTGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAGCAAGTGAGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTAGTGTTTTGTGATCTCTATTGTATTTCCTATTAAGGTTTCATATATTACTTTCCCATTGTTCCTGAATTTG
>NM_003218.4
AGTACCCAAGCGAGCCATTTAACATGGCGGAGGATGTTTCCTCAGCGGCCCCGAGCCCGCGGGGCTGTGCGGATGGTAGGGATGCCGACCCTACTGAGGAGCAGATGGCAGAAACAGAGAGAAACGACGAGGAGCAGTTCGAATGCCAGGAACTGCTCGAGTGCCAGGTGCAGGTGGGGGCCCCCgaggaggaggaggaggaggaggaggaCGCGGGCCTGGTGGCCGAGGCCGAGGCCGTGGCTGCCGGCTGGATGCTCGATTTCCTCTGCCTCTCTCTTTGCCGAGCTTTCCGCGACGGCCGCTCCGAGGACTTCCGCAGGACCCGCAACAGCGCAGAGGCTATTATTCATGGACTATCCAGTCTAACAGCTTGCCAGTTGAGAACGATATACATATGTCAGTTTTTGACAAGAATTGCAGCAGGAAAAACCCTTGATGCACAGTTTGAAAATGATGAACGAATTACACCCTTGGAATCAGCCCTGATGATTTGGGGTTCAATTGAAAAGGAACATGACAAACTTCATGAAGAAATACAGAATTTAATTAAAATTCAGGCTATAGCTGTTTGTATGGAAAATGGCAACTTTAAAGAAGCAGAAGAAGTCTTTGAAAGAATATTTGGTGATCCAAATTCTCATATGCCTTTCAAAAGCAAATTGCTTATGATAATCTCTCAGAAAGATACATTTCATTCCTTTTTTCAACACTTCAGCTACAACCACATGATGGAGAAAATTAAGAGTTATGTGAATTATGTGCTAAGTGAAAAATCATCAACCTTTCTAATGAAGGCAGCGGCAAAAGTAGTAGAAAGCAAAAGGACAAGAACAATAACTTCTCAAGATAAACCTAGTGGTAATGATGTTGAAATGGAAACTGAAGCTAATTTGGATACAAGAAAAAGGTCTCACAAGAATCTTTTCTTATCTAAGTTGCAACATGGAACCCAGCAACAAGACCTTAATAAGAAAGAAAGAAGAGTAGGAACTCCTCAAAGTACAAAAAAGAAAAAAGAAAGCAGAAGAGCCACTGAAAGCAGAATACCTGTTTCAAAGAGTCAGCCGGTAACTCCTGAAAAACATCGAGCTAGAAAAAGACAGGCATGGCTTTGGGAAGAAGACAAGAATTTGAGATCTGGCGTGAGGAAATATGGAGAGGGAAACTGGTCTAAAATACTGTTGCATTATAAATTCAACAACCGGACAAGTGTCATGTTAAAAGACAGATGGAGGACCATGAAGAAACTAAAACTGATTTCCTCAGACAGCGAAGACTGATTGTGTTTGTAAAAGCTTGATGAAAGGACAGTTAAGTATTTTGATCACTGCATTTTGTTTGAAACTTGTGTCATTGATGTAATTTAAAACTTTTGTTTAAAGCATTACAGTATTTTTCTGTGACCATCAATTAATGAGGGTTTGTGCTACCAGAGTTAAAGCATATGCTATCATTGTATTCTTTAAGAACCTTATTTTGATAAAATGTAAATTTGTTGAACCCTGCCACATTTAGTATCCCCACCCCCAAATCCTGTTCCAATGAAAAAATTAAAACCTGATACGAAAAAAAAAAAATTCCAGTTAACCTATTTTGTGTCTGTAGGCTGACCTCAACCCTGTAACGTAACCCATTAAAATGAAtttctttttttttaagacagagtttctctctgttgcccaggctggagtgcagtggcgcaatttcagctcactgcaacctctgcctcccaggttcaagtgattctcctgcctcagcctcctgagtagctgggattacaggcacacaccaccacgcccagctaatttttgtatttttagtagaggcggggtttcaccatgctggtcaggatgttctccaactcctgacttcatgatccacccacctcggcctcccaaagtgctgagattacagacgtgagccactgcgtcctgccTAAAATGAATTTTCTAGATGATTGAATAACAGTAGTCCTTTGATAGAAGATAATGACTTGGTTTATGGCCTTAATATACTACTTAATTACTTAAGATGTTTATTAATAGAATGATAAATGTACAGAGTAACCTATAAGCATGACATACTTTTGCTTTCAGTAGTTTCATGTAAAGAAAAAAACTTGAAAATAGTAATACCTGAGTACCCatgggaataatagacactggggaggtagggtggggagcgggagcaagagctgaaaaacttacctactggggactgtgctcactacctgggtgacaggatcatacgtaccccaaacctcaacatcacacagtatactcagctaacaaacctgcccatgtgtttcctgaatctaaaataaaaatcgaaaTAATTTTTTTAAAAAAGAAAAAGACAATAGTATTACCCATGGGACAAAATTTGTACTATTAGCAAGAATCATTTTGTGTCTCATTTAGAAACAATTTGACTTTTGTTCCAGTGTTTAAACTTTGACAAAAATGGTTTTGAATAGATCTTTATAACCTGATGCCATAAATACAAGATTCTCTGATACCTTCATTTAATATATCAATATTGGGCCTAAAACAGTATTCTGTAAAGCTTAAATTGGTATTAACTATGATCATCTTGATGTCTATGATAGATAATAAACAAGGTCATACATACCTTACTAAACAATTTTGGTTTTTCACCAACATTTTATTCTTTAAAAGATTTAGACTAACAGAATTATTTAGCATTTCGAGTCATGTGCTTTATTTAGCAAGTGAGTAAAAATATTGGAATATTGAAGTATTTGCATAAAAAATCAAATGGTGGTGTTTTGTAATCTCTATTGTATTTCCTATTAAGGTTTCATATATTACTTTCCCATTGTTCCTGAATTTGTTATCCTATATATAAACAGAAACATGGATGAGTACCATATACTTCCTGACTCCTTTATCTTGTTACACCACAAGATACTGCACTATTTATTGGAGATATTTTGATGATTAGTGCCAAGGCTGGCATCATGAGCCAAAATAGACTTGTTAAGTCAACCTCATTCCAAACACCTGCTATAGAtcatcaaatctaagttgccattaattgtaagatgtcctgttatttcacacacacaactagaaaagaaaaatcggtatcaattatagtatggtgctttcttattttgaattttacttattagaagagctattttagatgtatttaaacataagatttttatcacataacttgtggatacaaaaaaagagaaattgtaagcaaaataagttgggtaatatattcctaaaacctca

Publications

PMID - Link Title