Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FNTAP2
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:21530688-21531834  UCSC
Coordinates (T2T) chr13:20725016-20726162  UCSC
Coordinates (hg19) chr13:22104827-22105973  UCSC
Strand +
Parental Sequence NM_002027.3
Parental seq. overlap 1023 bp
Parental seq. overlap (%) 61.2%
Genomic Region Intragenic (MICU2)
Retrocopy Summary FNTAP2, located on chr13:21530688-21531834, is a retrocopy of the parental gene FNTA. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FNTA
Full Name farnesyltransferase, CAAX box, alpha
Also known as FPTA|PGGT1A|PTAR2
Coordinate chr8:43056323-43085785
Strand +
Gene summary Prenyltransferases can attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of proteins with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, May 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FNTAP2
Bonobo Pan paniscus FNTAP2
Gorilla Gorilla gorilla FNTAP2
Orangutan Pongo abelii FNTAP2
Gibbon Nomascus leucogenys FNTAP1
Green monkey Chlorocebus sabaeus FNTAP2
Crab-eating macaque Macaca fascicularis FNTAP2
Rhesus Macaca mulatta FNTAP2
Baboon Papio anubis FNTAP2
Golden snub-nosed monkey Rhinopithecus roxellana FNTAP2
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FNTAP2
TGGCCACTGAGGGGGTCGGGGAGGCTGCACAAGGTGGCGgGAAGAGATGGCGGCCGAGGCCAGGCAAGCCGTGGTGCCCCCATGGACGACGGGTTTCTGAGCCTGGACTCACCCTCCTACGTCCTGTACAGCGACAGAGCAGAATGGGCTGATATAGATCTAGTGCTGCAGAATGTTGGCCCCAATCCTGTGGTCCAGATCATTTACAGTGACAAATATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCCTGCAACTATTTGAAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAGTCAATTACTTGATTTACAACCAAGGCATAGTTCCCCCTACCTAATTGCCTTTCTTGTGGTTATCTATGAAGACATGCTAGAAAACCACTGTGACAAAAAGGAAGACATTCTTAATAAAGCATTAGAGTTATGTGAGATCCTAGCTCAAGAAAAGGACACTATAAGAAAGGAATATTGGAGATAGATTGGAAGATCCCTTCAAAGCAAACACAGCACAGAAAATGACTCACCAACAAATGTACAGCAATAACACCAACCCGAAAAACTTGATGGAATGCTTTTATTTTTTATTAAGGGACCCTGCAGGAGTTTAAAACGAGAGTGGTCCTTCCCTTTGCCTGTGGTGTCAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGATGCTCCTTGGGTGCTGCTGCTACTCAGACTAGCTGTAAGTAATGGGATTCTTCTAAAGCAAAGTCACTGGATGGGAGGAGGAAGAAAAAGTCCCATAAAGGAACTTTTGTAGTCTTATCAACATGTAATCAAATCCCTTAGCATCAACTCTTCCTTCAGTAGTACACGCGTCAAGATTTGTAGAAGTAATAACTGCAGGTCATTTGTATGTAATGGATATGAGGTAGCTGAAGTTTGGTTCAGTAAGCAGGGAATACAATACAGTGGTTCCATCAGAGCTGGTCTGCACACTCACGTTATCTTGCTATCACTGTAGCCAACTAATGCCAAAAAAACGGTTTTGTAATAAAAGCATAGCTGTATCTAAAAA
>NM_002027.3
ACCTCAGCTGCGGACCGAGGCGAGATGGCGGCCACCGAGGGGGTCGGGGAGGCTGCGCAAGGGGGCGAGCCCGGGCAGCCGGCGcaacccccgccccagccgcacccaccgccgccccagcagcagcACAAGGAAGAGATGGCGGCCGAGGCTGGGGAAGCCGTGGCGTCCCCCATGGACGACGGGTTTGTGAGCCTGGACTCGCCCTCCTATGTCCTGTACAGGGACAGAGCAGAATGGGCTGATATAGATCCGGTGCCGCAGAATGATGGCCCCAATCCCGTGGTCCAGATCATTTATAGTGACAAATTTAGAGATGTTTATGATTACTTCCGAGCTGTCCTGCAGCGTGATGAAAGAAGTGAACGAGCTTTTAAGCTAACCCGGGATGCTATTGAGTTAAATGCAGCCAATTATACAGTGTGGCATTTCCGGAGAGTTCTTTTGAAGTCACTTCAGAAGGATCTACATGAGGAAATGAACTACATCACTGCAATAATTGAGGAGCAGCCCAAAAACTATCAAGTTTGGCATCATAGGCGAGTATTAGTGGAATGGCTAAGAGATCCATCTCAGGAGCTTGAATTTATTGCTGATATTCTTAATCAGGATGCAAAGAATTATCATGCCTGGCAGCATCGACAATGGGTTATTCAGGAATTTAAACTTTGGGATAATGAGCTGCAGTATGTGGACCAACTTCTGAAAGAGGATGTGAGAAATAACTCTGTCTGGAACCAAAGATACTTCGTTATTTCTAACACCACTGGCTACAATGATCGTGCTGTATTGGAGAGAGAAGTCCAATACACTCTGGAAATGATTAAACTAGTACCACATAATGAAAGTGCATGGAACTATTTGAAAGGGATTTTGCAGGATCGTGGTCTTTCCAAATATCCTAATCTGTTAAATCAATTACTTGATTTACAACCAAGTCATAGTTCCCCCTACCTAATTGCCTTTCTTGTGGATATCTATGAAGACATGCTAGAAAATCAGTGTGACAATAAGGAAGACATTCTTAATAAAGCATTAGAGttATGTGAAATCCTAGCTAAAGAAAAGGACACTATAAGAAAGGAATATTGGAGATACATTGGAAGATCCCTTCAAAGCAAACACAGCACAGAAAATGACTCACCAACAAATGTACAGCAATAACACCATCCAGAAGAACTTGATGGAATGCTTTTATTTTTTATTAAGGGACCCTGCAGGAGTTTCACACGAGAGTGGTCCTTCCCTTTGCCTGTGGTGTAAAAGTGCATCACACAGGTATTGCTTTTTAACAAGAACTGATGCTCCTTGGGTGCTGCTGCTACTCAGACTAGCTCTAAGTAATGTGATTCTTCTAAAGCAAAGTCATTGGATGGGAGGAGGAAGAAAAAGTCCCATAAAGGAACTTTTGTAGTCTTATCAACATATAATCTAATCCCTTAGCATCAGCTCCTCCCTCAGTGGTACATGCGTCAAGATTTGTAGCAGTAATAACTGCAGGTCACTTGTATGTAATGGATGTGAGGTAGCCGAAGTTTGGTTCAGTAAGCAGGGAATACAGTCGTTCCATCAGAGCTGGTCTGCACACTCACATTATCTTGCTATCACTGTAACCAACTAATGCCAAAAGAACGGTTTTGTAATAAAATTATAGCTGTATCTAAAAA

Publications

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