Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BASP1P1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:22897029-22898194  UCSC
Coordinates (T2T) chr13:22095898-22097063  UCSC
Coordinates (hg19) chr13:23471168-23472333  UCSC
Strand -
Parental Sequence NM_006317.5
Parental seq. overlap 792 bp
Parental seq. overlap (%) 40.2%
Genomic Region Intergenic
Retrocopy Summary BASP1P1, located on chr13:22897029-22898194, is a retrocopy of the parental gene BASP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BASP1
Full Name brain abundant membrane attached signal protein 1
Also known as CAP-23|CAP23|NAP-22|NAP22
Coordinate chr5:17216823-17276834
Strand +
Gene summary This gene encodes a membrane bound protein with several transient phosphorylation sites and PEST motifs. Conservation of proteins with PEST sequences among different species supports their functional significance. PEST sequences typically occur in proteins with high turnover rates. Immunological characteristics of this protein are species specific. This protein also undergoes N-terminal myristoylation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BASP1P1
Bonobo Pan paniscus BASP1P1
Gorilla Gorilla gorilla BASP1P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BASP1P1
TATACTAACTTGTTTCAAATTGGAAGTAATGATATGTATGCCCAAGGAAAAATAAAGGATGTTGTCCCATCAAGGGAGGGAGGGAGTGGGAGAATGCAAATAGTATTTTTGTGGGGAAATATCTAATATAGCTTCAGTCAACTTTACCAAGAAGTCCTGGATTaAGTAGTGGCAGCTGCGACAAAGGCGGAGCTAGCACTACAACTGGCTCCTCGCTCTGGCCTCCGCCATGGAGCCAGGAGAGAGCCTCCGCCAGCGGCCAGGCATGAGCTAGACACCGCCAGGGACCCTGGCCTCTTGGGGGCACCGCGCTCACCCAGGGGCTGCACAGGCACCCAGAGCCAAACTCCAAGATGACAGGCAAACTCAGCAAGAAGAAGGGCTACAATGTGAACGACGAGAAAGCCAAGGACAAAGACAAGAAGGATGAGGGCGTGGCAAGGGAAGAGGAGGGTCCCCGAAGGAGAGTGAGCCCCAGGCAGCTGCAGAGCCCGCCGAGGCCATGGAGGGCAAGAAGTCTGACCAGGACGCGGAGGGCAAGGCCGAGGAGACAGAGGGCAAGAAGGATGCCACGGCTGCCAAGGAGGAGACCCCGAAGGAAGAGCCCGAGAAGACAGAGAGCGCGCAGAGGCCAAGGCTGACCCCCCGAGAAAGAGCAGGCAGCCCCCGTCCCTGCTAATGGCGGCGAGGCCCCCAAAGCTGCCGAAGTCACCACGGCCCGGGCCAAGAGCGCGGACCCTACCACTGGGGAGGAGCCCAGCAAGGAGGAAGGGAAACCTAAAAAGACTAAGGCGCCTGCAGCTCCTGCCACCCAGGAGACCATAAGTGACGGGCTCCAGCATGATACGCAAACCGCAGCAGCTCGGAGGCTGCCCCCTCTTCCAAGGAGACCCCCCGCAGCCAGGAAGCCCCTAGTTCCACACCCAAGGCCCGGGCCCCCACAGCCTCCGCAGAAGAGCCCAAGCCGGCGGAGGCCCTGGCAGCTAATTCCGATCAAACTGTAGCCATGAAAGAGTGACAAGGACAGCCTATGGGAAAAATAATACCACTTAAAACAGt
>NM_006317.5
agtagcggcagcggcgacgacggcggcggcagcgCTCCAACTGGCTCCTCGCTCCGGGCTCCGCCGTCGAGCCGGGAGAGAGCCTCCGCCAGCGGCCAGGCACCAGCCAGACGACGCCAGCGACCCCGGCCTCTCGGCGGCACCGCGCTAACTCAGGGGCTGCATAGGCACCCAGAGCCGAACTCCAAGATGGGAGGCAAGCTCAGCAAGAAGAAGAAGGGCTACAATGTGAACGACGAGAAAGCCAAGGAGAAAGACAAGAAGGCCGAGGGCGCGGCGACGGAAGAGGAGGGGACCCCGAAGGAGAGTGAGCCCCAGGCGGCCGCAGAGCCCGCCGAGGCCAAGGAGGGCAAGGAGAAGCCCGACCAGGACGCCGAGGGCAAGGCCGAGGAGAAGGAGGGCGAGAAGGACGCGGCGGCTGCCAAGGAGGAGGCCCCGAAGGCGGAGCCCGAGAAGACGGAGGGCGCGGCAGAGGCCAAGGCTGAGCCCCCGAAGGCGCCCGAGCAGGAGCAGGCGGCCCCCGGCCCCGCTGCGGGCGGCGAGGCCCCCAAAGCTGCTGAGGCCGCCGCGGCCCCGGCCGAGAGCGCGGCCCCTGCCGCCGGGGAGGAGCCCAGCAAGGAGGAAGGGGAACCCAAAAAGACTGAGGCGCCCGCAGCTCCTGCCGCCCAGGAGACCAAAAGTGACGGGGCCCCAGCTTCAGACTCAAAACCCGGCAGCTCGGAGGCTGCCCCCTCTTCCAAGGAGACCCCCGCAGCCACGGAAGCGCCTAGTTCCACACCCAAGGCCCAGGGCCCCGCAGCCTCTGCAGAAGAGCCCAAGCCGGTGGAGGCCCCGGCAGCTAATTCCGACCAAACCGTAACCGTGAAAGAGTGACAAGGACAGCCTATAGGAAAAACAATACCACTTAAAACAAtctcctctctctctctctctctctctctctatctctctctctatctcctctctctctctcctctcctatctctcctctctctctctcCTATACTAACTTGTTTCAAATTGGAAGTAATGATATGTATTGCCCAAGGAAAAATACAGGATGTTGTCCCATCAAGGGAGGGAGGGGGTGGGAGAATCCAAATAGTATTTTTGTGGGGAAATATCTAATATACCTTCAGTCAACTTTACCAAGAAGTCCTGGATTTCCAAGATCCGCGTCTGAAAGTGCAGTACATCGTTTGTACCTGAAACTGCCGCCACATGCACTCCTCCACCGCTGAGAGTTGAATAGCTTTTCTTCTGCAATGGGAGTTGGGAGTGATGCGTTTGATTCTGCCCACAGGGCCTGTGCCAAGGCAATCAGATCTTTATGAGAGCAGTATTTTCTGTGTTTTCTTTTTAATTTACAGCCTTTCTTATTTTGATATTTTTTTAATGTTGTGGATGAATGCCAGCTTTCAGACAGAGCCCACTTAGCTTGTCCACATGGATCTCAATGCCAATCCTCCATTCTTCCTCTCCAGATATTTTTGGGAGTGACAAACATTCTCTCATCCTACTTAGCCTACCTAGATTTCTCATGACGAGTTAATGCATGTCCGTGGTTGGGTGCACCTGTAGTTCTGTTTATTGGTCAGTGGAAATGaaaaaaaaaaaaaaaaaaaGTCTGCGTTCATTGCAGTTCCAGTTTCTCTTCCATTCTGTGTCACAGACACCAACACACCACTCATTGGAAAATGGaaaaaaaaaacaaaaaaaaaacaaaaaaaTGTACAATGGATGCATTGAAATTATATGTAATTGTATAAATGGTGCAACAGTAATAAAGTTAAACAATTAAAAAGAA

Publications

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