Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SDAD1P4
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:23268927-23269212  UCSC
Coordinates (T2T) chr13:22475694-22475979  UCSC
Coordinates (hg19) chr13:23843066-23843351  UCSC
Strand +
Parental Sequence NM_018115.4
Parental seq. overlap 229 bp
Parental seq. overlap (%) 7.6%
Genomic Region Intragenic (SGCG)
Retrocopy Summary SDAD1P4, located on chr13:23268927-23269212, is a retrocopy of the parental gene SDAD1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SDAD1
Full Name SDA1 domain containing 1
Also known as -
Coordinate chr4:75949911-75990962
Strand -
Gene summary Predicted to be involved in ribosomal large subunit biogenesis and ribosomal large subunit export from nucleus. Predicted to act upstream of or within cellular response to leukemia inhibitory factor. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SDAD1P4
Bonobo Pan paniscus SDAD1P4
Orangutan Pongo abelii SDAD1P3
Gibbon Nomascus leucogenys SDAD1P1
Gorilla Gorilla gorilla Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SDAD1P4
GAAGACTAGCCGCTGCAGTGGCTGGAAAGACTGACTGAAAAGAATATGTTAGAAAGAAAACCAATATGAGTGCAGTTTCCAGTGCCCCAAATAAAGAGAAGAAAACTAACTTTATATGATAATGTATTATAGCCAGAATGTCCAGTCAAAAAATAGATGTTCCTTCAGAAAAAAAGCAACTGGCACCATGAGATGTACTTTTGGAAAAAAGGGAAATAGAATAAATTATCTTCCAAACCAGTTTTTCATTCCAAGGATAATGCTGAATTTGTGTAATTGCTCTGAA
>NM_018115.4
ATACCCGGAAACACGAGTCCAAGCTGCAGCTGGCAGGGATTGCGGGGTGCCGGCCGTCTGAGTTTTTTTAAAACTGCTCGCCGCGAAGTCTGTCTGCAGCCAAAATGTCCAACAGAAACAACAACAAGCTTCCCAGCAACCTGCCGCAGTTACAGAATCTAATCAAGCGAGACCCGCCGGCCTACATCGAGGAGTTTCTACAGCAGTATAATCACTACAAATCCAATGTGGAGATTTTCAAATTGCAACCAAATAAACCCAGCAAAGAACTAGCAGAGCTGGTGATGTTTATGGCACAGATTAGTCACTGCTACCCAGAGTACCTAAGTAATTTTCCTCAAGAGGTGAAAGATCTTCTCTCCTGCAATCATACCGTATTGGATCCAGATCTGCGAATGACATTTTGCAAAGCTTTGATCTTGCTGAGAAATAAGAATCTCATCAATCCATCAAGCCTGCTAGAACTCTTCTTTGAACTTTTTCGTTGCCATGATAAACTTCTGCGAAAGACTTTATACACACATATTGTGACTGATATCAAGAATATAAATGCAAAACACAAGAACAATAAAGTGAATGTAGTATTGCAAAATTTCATGTACACCATGTTAAGAGATAGCAATGCAACCGCAGCCAAGATGTCTTTAGATGTAATGATTGAACTCTACAGAAGGAACATCTGGAATGATGCAAAAACTGTCAATGTTATCACAACTGCATGTTTCTCTAAGGTCACCAAGATATTAGTTGCCGCTTTGACATTCTTTCTTGGGAAAGATGAAGATGAAAAACAGGACAGTGACTCCGAATCTGAGGATGATGGACCAACAGCAAGAGACCTGCTAGTACAATATGCTACAGGGAAGAAAAGTTCCAAAAACAAGAAAAAGTTGGAAAAGGCAATGAAAGTGCTCAAGAAACAAAAAAAGAAGAAAAAACCAGAGGTGTTTAACTTTTCAGCCATTCACTTGATTCATGATCCCCAAGATTTTGCGGAAAAACTACTAAAGCAGCTTGAGTGCTGTAAGGAGAGGTTTGAAGTGAAGATGATGCTCATGAACCTTATCTCCAGATTGGTGGGAATTCATGAGCTTTTCCTCTTCAATTTCTATCCCTTTTTGCAAAGGTTTCTGCAGCCCCACCAAAGAGAAGTAACCAAGATCCTTCTGTTTGCTGCACAAGCATCTCATCACCTAGTACCCCCAGAGATTATTCAATCATTGCTTATGACTGTGGCAAACAATTTTGTTACCGACAAGAACTCTGGAGAAGTCATGACAGTAGGAATCAATGCTATAAAGGAGATAACAGCTCGATGTCCTCTGGCCATGACTGAAGAACTTCTCCAAGACCTGGCTCAGTATAAAACACACAAGGATAAGAATGTAATGATGTCTGCTAGAACTTTGATTCACCTCTTCCGAACACTGAATCCTCAGATGCTGCAGAAGAAATTCCGGGGTAAGCCTACAGAGGCCTCCATAGAAGCAAGAGTACAAGAATATGGAGAATTAGATGCTAAAGATTACATTCCAGGAGCAGAAGTTCTGGAAGTTGAGAAAGAAGAGAATGCTGAAAATGATGAAGATGGATGGGAAAGTACCAGTCTCAGTGAGGAGGAGGATGCTGATGGTGAATGGATTGATGTGCAACACTCTTCCGATGAAGAACAGCAAGAAATCTCCAAGAAGCTGAACAGCATGCCCATGGAGGAGCGGAAGGCCAAAGCTGCAGCCATCAGCACTAGCCGAGTTTTAACTCAGGAAGACTTCCAGAAAATCCGCATGGCCCAAATGAGAAAAGAACTTGATGCTGCCCCCGGGAAATCCCAGAAGAGGAAATACATTGAAATAGACAGTGATGAAGAGCCCAGGGGTGAATTACTTTCTCTTCGGGACATTGAACGCCTTCATAAAAAGCCAAAGTCTGACAAAGAGACAAGACTAGCAACTGCAATGGCTGGAAAGACAGACCGAAAAGAATTTGTGAGGAAGAAAACCAAAACAAATCCATTTTCCAGTTCGACAAATAAAGAGAAGAAAAAACAGAAGAACTTTATGATGATGCGGTATAGCCAGAATGTCCGGTCAAAAAATAAGCGTTCCTTCCGAGAAAAACAGTTGGCACTACGAGATGCACTTTTGAAAAAGAGAAAAAGAATGAAGTAACTTCCTGGCAAGTTTTCCATTCCTAGAAGAATGCTAAGTTTGTGTCCTTGCTCTGAAAATTGGTAAATCAAGCATGTTTGTTTACATTAAAAAGTCCAGACACACTGTATTGTGAAAACTGCTGAACATGTGGCAGCAATTTTGTGTTTTTATTTTGGAGACGGCTAATGGTAGGAATGTTAATGTAAATAGTGGTGGTAATGTAAAATCATTTCATTTAtcattcatgcaaaaaaaagtatgtattgagtgcctattcattgtcactgtagatgcaaaacgaatgagctgtaaccccttcactcaaggcattgacagcttagctgtgagggtggacacacatatgtgtatttacagtgcagtgtaaatagttctgtagtagaggttaactccatatttctgtgaggtcactgaggccttatggactaactctgtgaggataggAGTTATATATTCTTATAAGACAAAACAAAACAGGACAATGTTACAAGAGTAAGAGGTTCTTACTTGTACATAGGCTTTCCTGCTGAAAACAGGCCCCTGCTGTACAGATTTTGGGTACATAATTTAGCTCTTTTAGTCAATCCAAGAGATTTAAGTGACCCCCCCCCCCCCGTGttttttttgtttttgtttttgttttGAATGCCATGTAAAGGCTTTTTGGTTAAGACCTCACTTTTAAAACTGCCTTAAGTATAAATAGTACCTTTGGAATATATTTAGTTCATCATTTGAGCTGCCTTCATACTGGTTTCCTCAGCCTTCCTTCAGCCTGTAATATTTTCAGCCCACTGTTTACCTTGTCTCAATAAAAGGTTTCTAATGCCAAATA

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