Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name IFIT1P1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:32384628-32386641  UCSC
Coordinates (T2T) chr13:31601865-31603878  UCSC
Coordinates (hg19) chr13:32958765-32960778  UCSC
Strand +
Parental Sequence NM_001548.5
Parental seq. overlap 1502 bp
Parental seq. overlap (%) 34.6%
Genomic Region Intragenic (BRCA2)
Retrocopy Summary IFIT1P1, located on chr13:32384628-32386641, is a retrocopy of the parental gene IFIT1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name IFIT1
Full Name interferon induced protein with tetratricopeptide repeats 1
Also known as C56|G10P1|IFI-56|IFI-56K|IFI56|IFIT-1|IFNAI1|ISG56|P56|RNM561
Coordinate chr10:89392623-89406487
Strand +
Gene summary This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes IFIT1P1
Bonobo Pan paniscus IFIT1P1
Gorilla Gorilla gorilla IFIT1P1
Orangutan Pongo abelii IFIT1P1
Gibbon Nomascus leucogenys IFIT1P1
Green monkey Chlorocebus sabaeus IFIT1P1
Rhesus Macaca mulatta IFIT1P1
Baboon Papio anubis IFIT1P1
Golden snub-nosed monkey Rhinopithecus roxellana IFIT1P2
Crab-eating macaque Macaca fascicularis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>IFIT1P1
ACTGCAGAACTGCTGCCTAATTCACAGCAACCATGAGTAAAAATGCTGATGATCATCAGGTCAAGGATAGTCTGGAGCAGTTAAGATGTTACTTTACATGGGAGGTATCAATTAAAGATGATGAAATGCCTGATTTGGAAAACAGAGTCTTGGACCAGATTGGGTTTCTAGACTAAATACAGTGTGGGAATACACAATACACAACCTACTAGCCTATGTGAAACACCCGAAAGGCCAGAATGAGGAAGTGCTGGAGAACTTGAAAGAAGCTGAAGACTTAATCCAGAAAGAAGATGCCAATCAGATTTGAGAAGCCTGGTAACCTGGGGCAACTTTGCCTGGGTGTATTACCACATGGGCAGACTGGCAGAAACCCAGACTTACCTGGACAAGGTAGAGAACATTTGCAAGAAGTTTTCAAGTCCTTTCTGTCACAGAATGGAATGTCCAGAGATGGACTGTGAGGAAGAACGGGCCTTGCTGGAATGTGGAGGGAAGAATTATGAACAGGCCAAGGCCTGCTTTGAAAAGGATCTGGCAGTGGCTGCTGAAAACCCTGAACTCAACACTGGGTATGAAATCACCGCCTGTCGCCTGGATGGCTTTAAATTAGCAACGGGGGATCACAAGTCATTTTCTTTGCCTACCCTAAGGCAGGCTGTCAGGCTAAATGTAGATGATAGATATAGTAAGGTTCTTCTTGCCCTGAAGCTTTGGGATGAAGGACAGGAAGCTGAAGGAGAAAAGTACTTTGAAGGAGCTCTGGCCAATACGTCCATGCAGACCTTtgtctttggatatgtctttggatatgtcttCTCTTCTTACTGAAGAGAAGACTTTGTGGATGAAGCTCTTGAGCTCTTAAAAACCTCCTTGCAGGCAACTCCCACTTCTGCCTTCCTGCATCACCATATAGGGCTTTGTGACAGGACACAAAAGATCCAAATGAAGGAAGCTACCAACAAGCAGCCTAGAGGGCAGAACAGAGAAAAGGTAGACAAAATGATAAGATCACCTGTATTTCATCTTCAATCTGCTGTGGAACAAAAGCCCACATTTGAGGTTGCCTATATAGAACTGGCAGGAAAGTATATAGAAGCAGGCAATCACAGAAAAGCTGAAGACACTTTTCAAAAAGTGTTGTGCATGAAACCAGTGGTAGAAGAAATAATGCAAGACATATATTTGCACTATGGTAGATTTCAGGAATTTCAAAAGAAATCTGATGTCAGTGCAATTATCCGTTATTTAAAAGCAATAAAAATAGAAAAAGGCATAATTTTCAAGGGATAAAAGTGTCAATTCTTTGGAGAAACTGGTTTTAAGGAAACTTCAGAGAAATGCGTTAGACCTGGAAAGCTTAAGCCTCCTTAGGTTTCTGTACAAATTGAAAGGAAACATGAATGAAGCTCTAGAGTACTGTGAGTGGGCCCTGAGACTGGCTGCTGAGTTTTAGAACTCTGTGGGACAGGGTCCTTAGGCACTCAAATATTGACCACTTTCATATTTCATTTGATTTTCTGTTAACGTGCTAATCAaTGATAATCATCTTTTCTGCTTGCTGTTTTCAGAAACATATTATGTAATTCACTGTAATGATGTAATTATTGAACAGTTACTCAAATCTGATAAAATATTAGTTGCATTCAATAATTAATGAATCAATGTGTGTGTGCATGTAAGAAAAACCATTTGTATGAAGCAGAAAAAAAATGTTAGGTAGATTTGTAGGAAACAAAATACTGGACTTACACTAAA
>NM_001548.5
AACTGAAAATCCACAAGACAGAATAGCCAGATCTCAGAGGAGCCTGGCTAAGCAAAACCCTGCAGAACGGCTGCCTAATTTACAGCAACCATGAGTACAAATGGTGATGATCATCAGGTCAAGGATAGTCTGGAGCAATTGAGATGTCACTTTACATGGGAGTTATCCATTGATGACGATGAAATGCCTGATTTAGAAAACAGAGTCTTGGATCAGATTGAATTCCTAGACACCAAATACAGTGTGGGAATACACAACCTACTAGCCTATGTGAAACACCTGAAAGGCCAGAATGAGGAAGCCCTGAAGAGCTTAAAAGAAGCTGAAAACTTAATGCAGGAAGAACATGACAACCAAGCAAATGTGAGGAGTCTGGTGACCTGGGGCAACTTTGCCTGGATGTATTACCACATGGGCAGACTGGCAGAAGCCCAGACTTACCTGGACAAGGTGGAGAACATTTGCAAGAAGCTTTCAAATCCCTTCCGCTATAGAATGGAGTGTCCAGAAATAGACTGTGAGGAAGGATGGGCCTTGCTGAAGTGTGGAGGAAAAAATTATGAACGGGCCAAGGCCTGCTTTGAAAAGGTGCTTGAAGTGGACCCTGAAAACCCTGAATCCAGCGCTGGGTATGCGATCTCTGCCTATCGCCTGGATGGCTTTAAATTAGCCACAAAAAATCACAAGCCATTTTCTTTGCTTCCCCTAAGGCAGGCTGTCCGCTTAAATCCAGACAATGGATATATTAAGGTTCTCCTTGCCCTGAAGCTTCAGGATGAAGGACAGGAAGCTGAAGGAGAAAAGTACATTGAAGAAGCTCTAGCCAACATGTCCTCACAGACCTATGTCTTTCGATATGCAGCCAAGTTTTACCGAAGAAAAGGCTCTGTGGATAAAGCTCTTGAGTTATTAAAAAAGGCCTTGCAGGAAACACCCACTTCTGTCTTACTGCATCACCAGATAGGGCTTTGCTACAAGGCACAAATGATCCAAATCAAGGAGGCTACAAAAGGGCAGCCTAGAGGGCAGAACAGAGAAAAGCTAGACAAAATGATAAGATCAGCCATATTTCATTTTGAATCTGCAGTGGAAAAAAAGCCCACATTTGAGGTGGCTCATCTAGACCTGGCAAGAATGTATATAGAAGCAGGCAATCACAGAAAAGCTGAAGAGAATTTTCAAAAATTGTTATGCATGAAACCAGTGGTAGAAGAAACAATGCAAGACATACATTTCCACTATGGTCGGTTTCAGGAATTTCAAAAGAAATCTGACGTCAATGCAATTATCCATTATTTAAAAGCTATAAAAATAGAACAGGCATCATTAACAAGGGATAAAAGTATCAATTCTTTGAAGAAATTGGTTTTAAGGAAACTTCGGAGAAAGGCATTAGATCTGGAAAGCTTGAGCCTCCTTGGGTTCGTCTACAAATTGGAAGGAAATATGAATGAAGCCCTGGAGTACTATGAGCGGGCCCTGAGACTGGCTGCTGACTTTGAGAACTCTGTGAGACAAGGTCCTTAGGCACCCAGATATCAGCCACTTTCACATTTCATTTCATTTTATGCTAACATTTACTAATCATCTTTTCTGCTTACTGTTTTCAGAAACATTATAATTCACTGTAATGATGTAATTCTTGAATAATAAATCTGACAAAATATTAGTTGTGTTCAACAATTAGTGAAACAGAATGTGTGTATGCATGTAAGAAAGAGAAATCATTTGTATGAGTGCTATGTAGTAGAGAAAAAATGTTAGTTAACTTTGTAGGAAATAAAACATTGGACTTACACTAAATGTTTAATTCATTCATTTTATtgtgaaataaaaataaaatccttagctcctccaccaactgaacagaccctcttggccaaggagaccccagaaaccttaaaaactaagtttcccaaccatgacaagatgagagatcattcacacctcattatattccctcccttgctaactgccattggactttttccactgagttaaacagaaacccatggaaaacaaagaacagaagactcactccttggctgacttcacctagctcactccacgtagcgccacagccagactcccctcccctcttgcggtttccacatgacaactgatcagccttccctcctgataagtgaccactgcccacagactggttctggccagtccatggaggctgcacacagggtgcctctatgtcctttgtttcaccttttgatatagaaaggctaattttgctgtattttaatgttaagtctccaccacagagtgaacacagaatgcatgtgacatacatgtttacataccactattgtgtgactgcccctcatgaatattcatagccccccataacctgttaactatgtgtgtctagccaatccaccaaccataaaacttctgtaataccctcccttcctccaagagcctgcttttggttgctgtggtaggctctgcttcccaggctgCAGGTTGCAGGAGAGGAGGCTgcagtggctcacgcctgtaatctcagcacttcgatgggacgaggcaggcagatcacctgaacccaggagttcgagagcagccttggcaatggcaaaaccaaccgtctctacaaaaaatgcaaaaacttagctgggtgtggtggcatgcacctgtagcttcagttccagctactcaggaggctgaggtgagtggactgctggagccagggagttcgaggctgcagtgtcgagatcttgccactgcactccattctggatgatagaacgagaccccatctcaaaaaaaaaaaaaGTTCTCTCCAATTGTATATAGCTTGTGATTTTATGTCAACACTATCAATAAATAGCTTTCAgtgcaagaaaccaaaaatactgtaataaacaggcacatattcttcccaaacctcatgcagtttacaatctagtgagagacacagatagcagtacagagtcaattaAAGGTTAGTTTTCTTCATGAAGATGTTTTAATTTTAATTCAATGTGAAAGGGTTCCAAGGAGTTTATCTTGTTTTATGCCATTTTATTTGAAGCACTACTTACTAAGTCATTTGCTGATATTAATCTAGTTAAATCAAGAAATATTACATGAAAATGTTGCTAAATCAGAGATCATGGGTAACAATCACCTTTGATTATGAATAATCATATTTTATTGAAAGGCAAGGCACAACAAATAATAAGAAGGAAAAAATAAATAAGCAATGTTATTGATCTTTCATTCTGTATATGTTTTGGGGGGAAtatactagtttcttttagtggctgtaacaaattaccacaaacttggtgacttaaaatttcacagatttactctttcttacagttctggaggtcagaagtctgaaatgggtttcaatgagccaaagtcaaggtattgatgacgctacactcctccggaggctctaggcagatagccttttccagcttccagaggctgcctgaattctttcatccatcttaaaaaccaacagtgtagtagcctcaaatctctctctctgcttccttcttcacatctccttctctcctctgactcttttgcctctttcttctaaggacgcaccaggtccacctgcataatccagaataattgccccatccgcaaatccttaatttaataacatctgcaaagtcccttttgctatgtaaagtagcatgttcacaggttctggagacttggccatggatacgattgcggggggggcattattcttaccacaGAGCACCCCAAGAAAATCTCCAAATTTTGGGCTTCCAATCCATTTTGCTTCAATTATTTAATATTTTTACTCCTTCCAGTAGATACTGATTTCATCCATTGCCCTTAAGAAGGTAGGACAGAGATTATGGCACATCTCACATTAAATGCTATATTTTCGTTGGAAATACAttttttgcttcaacttttattttaaattcaagggtacatgtgcaggatgttcaggtttgttacacaggtaaacgtgtgccatggcggtttgctgaacagatcatcccatcaccAACAGATCATCCCATtgagaggtgaagccggctgggcttctgggttgggtggggacttggagaacttttctgtctagctaaagtattgtaaaatggaccagtcaacactctgtaaaatggaccaatcagctctctgtaaaatggaccaatcagcaggatgtgggtggggccaagtaagggaataaaagcaggccacccgagctggcagcggcaacccgctcgggtccccttccatgctgtggaagttttgttctttcgctctttcaataaatcttgctgctgctca

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