Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MICOS10P6
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:32496335-32496826  UCSC
Coordinates (T2T) chr13:31713592-31714083  UCSC
Coordinates (hg19) chr13:33070472-33070963  UCSC
Strand -
Parental Sequence NM_001032363.4
Parental seq. overlap 447 bp
Parental seq. overlap (%) 12%
Genomic Region Intragenic (N4BP2L2)
Retrocopy Summary MICOS10P6, located on chr13:32496335-32496826, is a retrocopy of the parental gene MICOS10. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MICOS10
Full Name mitochondrial contact site and cristae organizing system subunit 10
Also known as C1orf151|MINOS1|MIO10|Mic10
Coordinate chr1:19596979-19629820
Strand +
Gene summary Predicted to be involved in inner mitochondrial membrane organization. Located in mitochondrion. Part of MIB complex; MICOS complex; and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MINOS1P4
Bonobo Pan paniscus MICOS10P4
Gorilla Gorilla gorilla MICOS10P5
Orangutan Pongo abelii MINOS1P4
Green monkey Chlorocebus sabaeus MINOS1P1
Crab-eating macaque Macaca fascicularis MINOS1P5
Rhesus Macaca mulatta MICOS10P5
Baboon Papio anubis MICOS10P5
Golden snub-nosed monkey Rhinopithecus roxellana MICOS10P4
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MICOS10P6
GAGAGGAAAGCTGGAGCTGTGGGTGGGGAACATGTCAGAGGTGGGGCTCAGCAGGAAGTGGGACCAGTGCCTGCTGGATGTGGTAGATAAGTACCGGTTTTGGATTAGGGATTGTTTTCTCACTTACCTTCTTTAAAAAAAGAATGTGGCCATTAGCCTTTGGTTCTGGCATGGCATTAGGAATGGCTTATTCCAGCAGTCAGCATGATTTCCAGGTTCCATGTCTTCTACATGGAAAACATGTCAAAGGACAGGAGCAGTGACCACCTGACAACATCGCAGTGGGAGGAAAAGAGAAATCATGTTTATTCCTCAGGAATGCTGAAGTACCCTGGAGTAAGCTGTCATTCTTATTATAACAATGTTATTAGTAATGCTTTAAACTCCAGCACACTTGTTATGTATTTGAAACCAAGTCTGTTTCTTGTTTTGTATTTTCTCTCTGGAAATTGTAAGGCGGTGGTCTTAAATACATTAAACAAAAATAGGAAA
>NM_001032363.4
GCGAGACTTTCAGGGGTCGGAGCGCGGGGGCCGGCCGAGAGGAAAGCTGGAGGCGCGGGTGGGGAACATGTCTGAGTCGGAGCTCGGCAGGAAGTGGGACCGGTGTCTGGCGGATGCGGTCGTGAAGATAGGTACTGGTTTTGGATTAGGAATTGTTTTCTCACTTACCTTCTTTAAAAGAAGAATGTGGCCATTAGCCTTCGGTTCTGGCATGGGATTAGGAATGGCTTATTCCAACTGTCAGCATGATTTCCAGGCTCCATATCTTCTACATGGAAAATATGTCAAAGAGCAGGAGCAGTGACTTCACCTGAGAACATCCCAGCGGGAGGACAAGAGAAATCATGTTTATTCCTCAGGAATACTGAAGTGCCCTGGAGTAAGCTGCCATTCTTCTGTAACAATGTTATCAGTAATGCTTTAAACTCCAGCACCTGGTTATGCATTTGAAACCAAGTCTGTTTCTTGTTTTGTATTTTCTCTCTGGAAGTTGTAAGGAGGTGGTCTTAAATAAATTAAACAAAAAGAGGAAGTCCATTGCATGGCCTTTGTTTCTTCACCTTTGGTCTCTGAGCATGAGGAGGACTGTGTGTGAACTGCCAGCAGCTGTAGCCACCTGCTCACAGCCTCTCTGAGAACCCCCTGAAACCAGTTGTTGGGTATCCTTCCCATTTGCCCCCTCAGGCGTAGTTTTCAGAACTGCTTCCACCTCGTAATCAGAAGTTGAAGATTGCTGCTGCGTGGCCTGATGGAGATGACTGATGTCTTAAGGCGCCTTTCCTTCTGTGGCACCTCTTCGTGTGTTCTCACCTGGGGACCTGGCAGGGCACATCTCCGCTGTGCCTACTGCAAGGCGGTCCCACTGCTGCTGTATTAGCAGGGGAAGAATCCTGGCTGTGTGGATGGCCCACTCCATTGAAGTCAAGTCCTGCAGCTTCATAGAGCTTGAGACAGTCCAAGCTTCAGCTCTGGAGGGCGGAGGAAAGCTCATGGCATACCCACCTGGCCGGAGGAGCCCGATTGGGGTTAATTTTATCTTCACGTAGCAGCTGAAGTTTGAGGACAAAAGGGCCACTTCTGATGCCCCTCTGAGTTTGTTCCTGTGGTTTCACTTGAACCAGGGATGCTAGATGCAAAAGTCATATTTTAGCAATTTCTTCAGACGATATACAGAACCCCAGCGCTCAGCCGTTCTTATTTCTTTTTCCTTATCGTAGAATTAAGATAGGGAGAGCCCGATCCCACTTGCCCCTGTatcctgtaaatgttgatttatcatctactgtaagcgaggcactgttgtaagcagcagagataaatggataaatagacacaggcttctgccttcaaggagcttagagtctgatggaaagacagacgtgcaaacacaactctgaaagaagtgttttaatggagaagagaggtgtaggcaaagtacactgagaacaaaggagaaggagcaactatgtctccctaggatggccccacaggcgacggaatgcctgcgctgggacccgaagttgactgggaatcccagacagaaggagggtagcctctgtgtttgctcaggatcatgtaatgcatattatagctgggaaatcgcaagtagttcagcatagccagggtgtgtaggggcaggggaaaggcatggagggggaggctggGCAATAGGGTACAACTCATGTCTGACTCCAGTTCTGGAACATTGATTAGACCTTAGTTCTTGCAAGTGCTATAGTGAGTACATTCAGGGTAGCAAATACCCTCCCTCAGCCTCCCCACTCCCTTTTCCAGAAAGGTCTGCTAGGCTCTGCCCTGCAAACTGTCCAGGCTCCTCTGCCCTCTGGGCTTGTTTTCCTCTTTATTGCTACTTGGCTGTTTTTCACTTGGTCCTCTTCATTCTATGATTAAGGCAACCCATATAATTGAAAGAAAAATAATGTGCAGCCTGTTTCATCCCTTCCACTTGttttcttactatttatttatttatttctgagatggaattttgctcttgttgcccaggctggagtgcaatggtggcgatctcggcctgctgcaacctccgcttcctgggttcaagcgcttctcctgcctcagcctcccgagtagctgggattacaggcatgcgccatcacacctggctaattttgtatttttagtagagacggtgtttctccttggtcatgctggtctccaactcccgacctcaggtgatcctcccgcctcggcctcccaaagtgctgggattacaggcgtgagccaccgcacccagccTCCTATTTGCTTTAAAAGTAATTTCCTggccggatgcggtggctcacacctgtaatcccagcactttgggaggccaaggcaggtggatcatgaggtcaagagatcaagaccatcctggccaacattgtaaaaccctgtctctactaaaaatataaaaatcagctgggcatggtggcgcacacctgtagtcccagctactcaggaggttgaggcaggagaatcatttgaacccgggaggcagaggttgcggtgagctgagatcgcgccactgcactccagcccggcgacagagcgagaatctgtctcaaaaaaaaaaaaaaaaaaaaaGCATTTTCCTTCCCCAATTTTTCTGTCATTTTCCCATCCTCATTCAGGCAGAGAGAAGAATAACATGCCCCCTTCCAAAAAAGACAAAACACAAGGTAGCCACAAATTCCCTAGACACATTAGAAAAATAGGGAGTGGAGAGGGGCATTGGAATGAAAGTTCTCTATCTCATTAGCTGTTAGGCTTTAGGCATTTATTTGGATGGATCCCTTTGGCACCTTGGAAGCACCACTGAAGTGCTCTGAGAAAGGGGTCAGCTGTCTGAGGGAATAGTTCTGGATAGAGGCCACAGGAAGCACTGGCCAGTTGCTTTAGTTCTAGATAGCTTTGTATTCCCGCCTTGTTGCCCTTAGCGGAGGCTGGCCCAAAGCACACTTGATCTTGTCCCCACTCCCTGCCCCCATCTCAGATCAACCTTCAGAAAGTCCCGGCTTGTTGGCAAAGGCACACATTCTGTGTTACTCTTAAGTTTCATTAGAAATTCAAGTCCTCTGGGGCCCTGTTCCCTTGTGGGCTTGTGCAACTGACTTTGTTTCTTGTCTGCCTTTCTGGAACCAAATCCAAGGAAATTCATGGGTTTGGGGAGACAGCGATGGGAACCCAGCAGGGCACAGGATGCTAGGATAAAGCTGTGGCGCCCCAAAAGTGGCCTGCTCTGCCAACATACATAAATACATACAGTCTGAGCTTGACACTGTATAATTTGGCCCAGAACAATATGTATTTTGAGCTCATTTAGGTGAATGACTTTGGCATTCCATGTACCCACTAGGGGAAGCTTTATCAGGCTGCATTTGCCTTATGCAGAAGTATGCCTTTGTTCTGAGAAATGGCCTCAGAACACACTGTTGAGCTGTCTCCTTTAGTGAGTGTCATCCTCTCATCCATTTCAAAAGATTGCAGATGCCGTCTTGAAGTCCTGCTTGTAAGAAATGCAGGGGTTGGGAATGGAGGAGATGACGATGTAGTTTTGCTTTTAGTTTTCCCAAACCTGTTTACATTTTTTAAAAATGTAACCAACCCATAATTGCATTTTACTTGTCGTGGTTCGATCTGATTGTATTGTCGAAGGACTATTTTTGAACCTGTCCAAATAAACTCTGCAAAGTATTTCCACAA

Publications

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