Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RLIMP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:40618625-40620498  UCSC
Coordinates (T2T) chr13:39837603-39839476  UCSC
Coordinates (hg19) chr13:41192762-41194635  UCSC
Strand +
Parental Sequence XM_017020685.2
Parental seq. overlap 802 bp
Parental seq. overlap (%) 21.4%
Genomic Region Intragenic (FOXO1)
Retrocopy Summary RLIMP1, located on chr13:40618625-40620498, is a retrocopy of the parental gene RNF6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RNF6
Full Name ring finger protein 6
Also known as -
Coordinate chr13:26132115-26223085
Strand -
Gene summary The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RNF6P1
Bonobo Pan paniscus RNF6P1
Gorilla Gorilla gorilla RNF6P1
Orangutan Pongo abelii RNF6P1
Gibbon Nomascus leucogenys RNF6P1
Green monkey Chlorocebus sabaeus RNF6P1
Crab-eating macaque Macaca fascicularis RNF6P1
Rhesus Macaca mulatta RNF6P1
Baboon Papio anubis RNF6P1
Golden snub-nosed monkey Rhinopithecus roxellana RNF6P1
Marmoset Callithrix jacchus RNF6P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RLIMP1
AGTTGGGAAGAGATGGACAGCTCTCCAAAAAGGCACAAACAATTGAAGGATGGATACCATGGCATATGTTAAAAGCATATTGAAAGGAAAATAAGAAAGCCAGGAATCTCAGGATGAATCAGTCTAGATCTAGATCAGATGGTGGTGGTGACGAAACCTTATCTCAAGACCGTAATCATTTGTGAAAATGGGAGAAGATGGCAGCAAGAGCATCTCCACAGAGAAGAGGCCTGAGAACTCGATGAAGATTATCGGCTTATGAGAGGACCATAATCTTTTAGGCTCCCCTAGAGAAATAACATCAGAAGAACTGCAACAGTGGTTAGATGGGGTCAACAAACAACTAGCATCTCAGCCTGACTCGAGAAATGGAACAAACTaTGGAACAAATTACAGAGACTCAGAAGTCCCCAGAGAAAGTTCAAATGAATATTCTCTTCTAGCATAGTTGAACACCTTTCGGGGCACAGGAAATGCAACTCAAAGTGGACAAAATGGGAATCAAAATTGGAGAGCTGTGAGTCGAACAAACTCGAACAGTGGAGAGTTTCGGTTTAGTTTGGAAATCCACATAAATCATGAAAATAGAGGATCTGAAATTCATGGAGATTATACAAACATTCCACTTTCAGATAGTAACAGAGATCATATTACAAATAGGCAACAAAGGTCATCTAGTCCTGTGGCTAGGCGAACAAGAAGCCAAACCTCAGTGAATTTCAATGGTGGTAGTTCCAACATTCTAAGGACTAGGCTTGCTTCAAGGGGGAAAAATTCAGCTGAAGGATCTTTCTCAACAGTAGGAAGATTAAAAAATGGAACTGGGGGATCAGCTGGCATTCCCAGAGCTAGTGCTTCACGCACTAATTTCAGTAGTCACACAAACCAGTCGGGTGGCAGCTAACTCAGGCAAAGGGAGGCACAACAGTTTAAAGCAGCACATGTTTGGGAAAATGGGGCTAGATATAATGTTACAGTGAGAAATACAAACCAAAGATTAGGGCCAATAAGATCTACTATAAGTAGCCGAAGCTGTTCACCAATTCAGAGACACAGTGGCACTGTTTGTCATAATTCACAAAGGGAAAGTAGACCAGTACAGCAAACCACTAGAAGATCTGTCAGGAGGAGAGGTATAACTCAAGTCTTTTTAGAGCAAGATAGAGAACACAGAGGTACTGCATATACCCCATTCTCTAATTCAAGACTTATGTCAAGAATAACAGTAGAAGAAGAATCCAGCAGATCCTCAACTGCTGTACTACGACATCCAACAATCACACTGGACCTTCAAGTGAGAAGGATCCATCCCGGAGAAAATAGAGATCAGGACAGTATTGCAAACAGAACTCATCCAGAGTAGGGCTAACAGAACATACAGTCACTATTCAAAGCAATAGTGGGGGCTTCTGCCGAATCATTTCTCGTTTAGAGCGGTCACGTATTCAAACCTATGTTAGTACCATAATTCTTCCTAGGATTTCTGAGAACGAGCTTGTTGAGCCATCATCAGTGGCTCTTCGGTCAATCTTAAGGCAGATTATGACTGGGTCTGGAGAA
>XM_017020685.2
GCACGGGCGAGCTCCGGGCCGGCTGCGGAGCGACTCCCCGCCGCCAAGTGGGCGGCGTGGCTGTCGGGAAAGAAGGGCTGGGGCCTGCCGTTCTTCCTCCCGAGTATCCCCTCCAGCTGGACGACCCCACGCTGCAGCACGGGCTTCCGGCTTCTCTCCTCAGTGGCCAATTCGAGGGCACAGCGGGCTCCGGAGGCGCGGCGGCAAGCCTATCCCGCCTCCCAACCACAGCCTCCAGCACCCGAGAGAACGGCCGCCCACAGCACACGTTCTCCGGACAGGAGGGCGAAGGCCCAAGACCTGGAGAGGTGGGCTCGAGGGAAAGATCTGGGTCCCACCACTACTTCCTGGAGACGCCGGGGAAAGCAGGCCATCCTTCGAGCCACCCATCTCTTCTCCGATTGGTTAACTGCCTTCTTATTGCGCTCCGCTGGCTGGTGATTGGTTGGGATGCACCGTCTATCACCTGCTTCCTTGTGAGAATCTAGGTCTCTAAGGGAAGCGTTACTTGAGGCTCGGTTGGGAAGAGATGGGCAGCTCTCAAAAAAGGCACAAACAATTGAAGGATGGATACCATGGCATATGTTAAAAGCGTGTTGAAAGGAAAATAAGAAAGCCAGGAATCTCAGGATGAATCAGTCTAGATCGAGATCAGATGGTGGCAGTGAAGAAACCTTACCTCAAGACCATAATCATCATGAAAATGAGAGAAGATGGCAGCAAGAGCGTCTCCACAGAGAAGAGGCCTATTATCAGTTTATTAATGAACTCAATGATGAAGATTATCGGCTTATGAGAGACCATAATCTTTTAGGCACCCCTGGAGAAATAACATCAGAAGAACTGCAACAGCGGTTAGATGGCGTCAAGGAACAACTAGCATCTCAGCCTGACTTGAGAGATGGAACGAATTACAGAGACTCAGAAGTCCCTAGAGAAAGTTCACATGAAGATTCTCTTCTAGAATGGTTGAACACCTTTCGGCGCACAGGAAATGCAACTCGAAGTGGACAAAATGGGAACCAAACTTGGAGAGCTGCTTGTGTCAAGAATAACAGTAGAAGAAGGAGAAGAATCCAGCAGATCCTCAACTGCTGTACGACGACATCCAACAATCACACTGGACCTTCAAGTGAGAAGGATCCGTCCTGGAGAAAATAGAGATCGGGATAGTATTGCAAATAGAACTCGATCCAGAGTAGGGCTAGCAGAAAATACAGTCACTATTGAAAGCAATAGTGGGGGCTTTCGCCGAACCATTTCTCGTTTAGAGCGGTCAGGTATTCGAACCTATGTTAGTACCATAACAGTTCCTCTTCGTAGGATTTCTGAGAATGAGCTTGTTGAGCCATCATCAGTGGCTCTTCGGTCAATTTTAAGGCAGATCATGACTGGGTTTGGAGAACTGAGTTCTCTAATGGAGGCCGATTCTGAGTCAGAACTTCAAAGAAATGGCCAGCATTTACCAGACATGCACTCAGAACTGAGTAACTTAGGTACAGATAACAACAGGAGCCAGCACAGGGAAGGTTCCTCTCAAGACAGGCAGGCCCAAGGAGACAGCACTGAAATGCATGGTGAAAACGAGACCACCCAGCCTCATACTCGAAACAGTGACAGTAGGGGTGGCAGGCAGTTGCGAAATCCAAACAATTTAGTTGAAACTGGAACACTACCCATTCTTCGCCTTGCTCACTTTTTTTTACTAAATGAAAGTGATGATGATGATCGAATACGTGGTTTAACCAAAGAGCAGATTGACAATCTTTCCACCAGGCACTATGAGCATAACAGTATTGATAGTGAACTAGGTAAAATCTGTAGTGTTTGTATTAGTGACTATGTAACTGGAAACAAGCTCAGGCAATTACCTTGCATGCATGAATTTCACATTCATTGTATTGACCGATGGCTCTCAGAGAATTGCACTTGTCCGATCTGTCGGCAGCCTGTTTTAGGGTCTAACATAGCAAACAATGGGTAAGGTGATGGGATCTACTCAAATACTGTTTTTTAGTAGAACTGAATGTTCAAGCATTGTTTTGCTGAGTTATTTGTGATTAGCTAACCAGGATGAAAAATAACAGATTATATATAGTTTGAACTATTTTTCGTGTGCTTTTTTAAACTTGttaaaaagaaatttatataaaatttaaaatacaaatgttaaattATCCAGAAATACAGAATAGTTAATATTGCTAGAACCAAATAACCTCTAAAATGTTTTTATTTTGGTAATTTTGTCATGCTAAGCACTTTTGTATCTGCACAATTCAGTAGGTTAAGAATCAATCTTCTTTTTCTTAATAGTACAGCAGACTTTAGCTTCAAGTTTCATAGGCTTAGTACTTATATCTAGACATTTGTGTCTAAATAAGCTTTTCATTAACTTTTTATTTTAAGGACAGTATCTTTTCATGAAAGAGTATTTGGCTGAATGTTTGCTATATATATGTTACTTGAAATGTTAAATTTAATATGCAGCATACCATAGGTGTATATATAGGTATATAATTTTAAGGTTAAAATATTCAGTCTACAAGTTTGGTTCTTATTTAAGCTTTTGGGCTAATACTGCATATGGCACAATGTTTAATATTGGCAAGTTCATCTCAGAGAAAGGGGATTCAGATATAATTTTAAAGTAGAGATAATTTACTGAAGCGTCTCTGACAATCTAACTTATTAGACAGCAAGCAATATATAATACTGAAAAAGTATTCAGAAATGGAAAATTTACATCATATAGGTTATTTAACTTGTGTTCAGCCTTTTTGTAACTTTTTTGAAAGTGCAAACAATTCTTTGGATTATTAAATAAGGTATACAGTATGCATGGTTTCTCAAATTTAGTTTTAAAATCTAAAAGTCTATAAAGAATCAGATGCATAGGCAATATGTTAAGTTCACTTGGAGGCTAAAAATCTCCAGTGAAAACAAAACGAAAACCTTTAAGAGAATGTAGAGTTTATATAAACACAAAGTATGCATTGAAGATCTGTTTCTACCAATAAACATTAAAACAAAGACTGTATGTGAACTA

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