Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ABITRAMP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr9). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:46270052-46271888  UCSC
Coordinates (T2T) chr13:45491068-45492904  UCSC
Coordinates (hg19) chr13:46844187-46846023  UCSC
Strand +
Parental Sequence NM_017832.4
Parental seq. overlap 1359 bp
Parental seq. overlap (%) 70.7%
Genomic Region Intragenic (LRRC63)
Retrocopy Summary ABITRAMP1, located on chr13:46270052-46271888, is a retrocopy of the parental gene ABITRAM. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ABITRAM
Full Name actin binding transcription modulator
Also known as C9orf6|CG-8|FAM206A|Simiate
Coordinate chr9:108934397-108950745
Strand +
Gene summary Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Predicted to be located in growth cone. Predicted to be active in several cellular components, including dendrite; filopodium tip; and lamellipodium. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FAM206AP1
Bonobo Pan paniscus ABITRAMP1
Gorilla Gorilla gorilla ABITRAMP1
Orangutan Pongo abelii FAM206AP1
Gibbon Nomascus leucogenys ABITRAMP1
Green monkey Chlorocebus sabaeus FAM206AP1
Crab-eating macaque Macaca fascicularis FAM206AP1
Rhesus Macaca mulatta ABITRAMP1
Baboon Papio anubis ABITRAMP1
Golden snub-nosed monkey Rhinopithecus roxellana ABITRAMP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ABITRAMP1
aGGGGTGGTGGCGCCTGAGGTCACCATGGCTACCGAGCGCCAAACCGCAGAGCCGGTGGTGCCTTTGTTCGTGGATCAATACTTCACTCGCTGGTACAAAGCAGATGTCAAAGGAAGATCTTGTAAGGACCACTGTATACCACAGCACTCTAACCGAATATGTGTCATCACATTGGCAGAATCTCATCCAGTTCTTCAGAGTGGAAAAACAATTAAAAGCATTCCCTGTCAGATCAGTCCCAACTGTAGCAGACTTCAGAACAAGGTCTCTGGGAAATTTAAGTGGGGGGCACAGTTTCTAACAGAACTTGCACCTCTCTGTAAGATTTACTGCTCAGATGGCGAAGAATATACTGTATCTAGTTGTGTTAGAGGATGTTCGATGGAAGTGAATGAAAAACATTCTCCATAAGCCATCTATTCTTCAAGAAAAGCCATCACTGAAGGCTACATTGCAGTTGAGTTACCCAAATTTGAAGAAAGTAAAAACATAACAGAAGGGTTACTGACACAAAAACGGTATGAAGAAGTCATGGTGAAATGCATTAATGCCACAACAGTGACGTCATGAGGACTGACATGGAGCAAAAAGCAAAGTGGGATTCTTGTTACCTGGCCTAAACCATCAGTGCACGAAAGGAGAAGAACCAGTATCTGTGAAGCATACTTCACAGCCATAGGCCGAGGAGGCCTGGTGCTTCACTTACCTTCGTTTCCCCTCTCTGGCTTGCATAATGAGCCTTGGTTCCCATTTGTCTTCAGCCTGCCAGATCTGGCCTGCCCATGTACTTACCCTGTTCTCTTGCATCTCTCTAACAACTGGCATGCAAGGAATGcTGTTTGAACATTATGGTATGGTTATTGCTTTTGCCTCATTGTCCTATTAGTTTGAAGTTTAAAAAAACCTAACCCGCCTTTCTTACCCAATCTGCTATAATGTGACGACCAAAAAGTCTAGTCCCAGCCCATCTGCCTCAACTCCTCTCCCTTTTAGGTTGTAGGGAAGAGGCTGGAGTGCAGATTGTATCTTCTGCCCTCCTTATGCCAACAAGATGGCCTTCCCCTCTGAAACAAAGTAAAACTGCAACACTGTGACTGCTTAAATGAGGGATATGTGAAAAGGCTATGAAAAATACAAAAGCTTTCCTAGGAAATGTATTATAATGCAGTGGGAAGCTAATTACTGAAATATGCATATTGTAGTCACTCAGTCTCACATACTCTAGTTACCAGCAAATAAGTTACTGAGAATATGTCATTCAAAGGCGTAGAAGCCTTTGAAAGGAGCAAATGCTTTCACATCATTTAAACTAAAAAAAAAAAAAAAACTCCAACAACTATGAATTTATAGTTTAAGATCAGTTAACACTGAATTTCAAATAAAAGGACTATAAAACTTGTCATTTTTCTGTAAGGGCTGTAACACATAAATACATTTCAATATCCCTGTTTTTAAATAAAATACACATTTATACAGAA
>NM_017832.4
GTGCGCCGGAAGAGCACGCCCAGTCCGGGCTGCGCGGAGGAAGCGCTGGGGTCCCGGAGGGCGGGGGTGGCGGCGCCGGAGGTCGCCATGGCTACCGAGCCCGAAGCCGCGGAGCCGGTGGTGCCTTCGCTCGTGGATCGATACTTCACTCGCTGGTACAAACCGGATGTCAAAGGAAAATTTTGTGAGGACCACTGTATACTACAGCACTCTAACCGAATATGTGTCATCACATTGGCAGAATCTCATCCAGTTCTTCAAAGTGGAAAAACAATTAAAAGCATTTCCTATCAGATCAGTACCAACTGTAGCAGACTTCAGAACAAGGTCTCTGGGAAATTTAAGCGGGGGGCACAGTTTCTAACAGAGCTTGCACCTCTCTGTAAGATTTACTGCTCAGATGGTGAAGAATATACTGTGTCTAGTTGTGTTAGAGGACGTTTGATGGAAGTGAATGAAAACATCCTCCATAAGCCATCTATTCTTCAAGAAAAGCCATCTACTGAAGGCTACATTGCAGTTGTGTTACCCAAATTTGAAGAAAGTAAAAGCATAACAGAAGGGTTACTGACACAAAAACAATATGAAGAAGTCATGGTGAAACGCATTAATGCCACAACAGCTACGTCATGAGGATTGACATGGAACAAAAAGCAAAGTGGGATTCTTGTTACCTGGCCTAAACCATCAGGGTACTAAAGGAGAAGAACCAGTATATGTAAAGCATACCTAACAGCCAGCCATATGCAGGGGAGGCCTAGTGCTTCACTTAGTTTTCCCTCTCTGTCTTCATAATGAGCCTTGGTTCCCATTTGTCTACAGCCTGCCAGATCTGGCCTGCCCATGTACTCACACTGTTCTCTTGCATCTCTCTAACAACTGGCATGCAAGGCATGtttttctgattaaaaacaaacaaagctctttgaagaagatttagaaaatacagaagagttttaagtagccaagtaaaaataatttacccatcatcccataatccagaagtaaATAcatttgacccttgagcaacataggtttgaactgcaagggtccacttatgcatggactattttcaactataaacgagtcaaaaatatatcattaaccaaacacgaaacccacttatagagcaggttcatatactcaggttccaaagggccaactgcaggacttgagttctcacgtatggatttgggtatatgtggaagttcctggaaccaatcccctatgtaaaccaagggataactACTACATTTTAACCTACTTCTGTTTGAACATATGGTATGGTTATTGCTTTTGCCTCGTTTTCCTAACAGTTTGAAGTTTAAAAAAACCTAACCCACCTTTCTTACCCAGTCTTCTATAATGTGCCTACCAAAAAGCCTAGTCCTAGCCCATCTGCCTCAACTCCTCTCCCTTTTAGGTTGTAGGGAAGAGGCCGGAGTGTAGAGTATATTATATCTTCTGTCCCCCTTATGCCAACAAGATGGCCTTCCCCTCTGAAACAAAGTAAAACTGCAACACTGTGACTTCTTAAATGAGGGATATGTGAAAAGGCTATGAAAAATACAAAGGCTTTCCTAGGAAATGTGTTATAATGCAGCGGGAAGCTAATTCTTGAAATATGCACATTATAGTTACTCAGTCTCACATACTCTAGTTACTGGCAAAGAAGTTACTGAGAATATGTCATTCAAAGGCATAGGGGCCTTTGAATGGAACAAATGCTTTCACATCATTTAAAGTAAAAAAAAACCTCCAACAACTGTGAATTTATAGTTTAAGAGTGATTTACACTGAATTTCAAATAAAAGGACTATAAAACGTGTTATTTTTCTGTAAGGGCTATAACATACATGTCAATATCACTGTTTTTAAATAAAATATACTTTTATACAGAA

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