Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name UTP14AP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:52028757-52031229  UCSC
Coordinates (T2T) chr13:51243573-51246045  UCSC
Coordinates (hg19) chr13:52602893-52605365  UCSC
Strand +
Parental Sequence NM_006649.4
Parental seq. overlap 2284 bp
Parental seq. overlap (%) 91.1%
Genomic Region Intergenic
Retrocopy Summary UTP14AP1, located on chr13:52028757-52031229, is a retrocopy of the parental gene UTP14A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name UTP14A
Full Name UTP14A small subunit processome component
Also known as NYCO16|SDCCAG16|Utp14|dJ537K23.3
Coordinate chrX:129906131-129929752
Strand +
Gene summary This gene encodes a member of the uridine triphosphate 14 family. As an essential component of a large ribonucleoprotein complex bound to the U3 small nucleolar RNA, the encoded protein is involved in ribosome biogenesis and 18S rRNA synthesis. An autosomal retrotransposed copy of this X-linked gene exists on chromosome 13. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes UTP14AP1
Bonobo Pan paniscus UTP14AP1
Gorilla Gorilla gorilla UTP14AP1
Orangutan Pongo abelii UTP14AP1
Gibbon Nomascus leucogenys UTP14AP1
Green monkey Chlorocebus sabaeus UTP14AP1
Crab-eating macaque Macaca fascicularis UTP14AP1
Rhesus Macaca mulatta UTP14AP1
Baboon Papio anubis UTP14AP1
Golden snub-nosed monkey Rhinopithecus roxellana UTP14AP1
Marmoset Callithrix jacchus UTP14AP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>UTP14AP1
GCCTTCGGCTTCCATTCTTGGTATACATGAGAGAGGCTGGCTGCTGAGATGAATGTGAACCAGGTTGCAGAGAATCTGGCTTTGAGCCACCAGGAAGAACTAGTGGATTTGCCAAAAAACTACCCCTTGAGTGAAAATGAAGATGAGGGGGACAGTGATGGAGAGAGAAAGCATCAAAAGCTTCTGGAAGCAATCATTTCCCTTGATGGAAAGAATAGGCGGAAATTGGCTGAGAGGTCTGAGGCTAGTCTGAAAGTGTCAGAGTTCAGTGTCAGTTCTGAAGGATCAGGAGAAAAGCTGGGCCTTGCAGATCTGCTTGAGCCCGTTAAAACTTCATCTTCTTTGGCCACTGTAAAAAAGCAACTGAATAGAGTCAAATCAAAGAAGGTGGTGGAGTTACCTCTTAACAAAGAAAAAATTGAACAGATCCACAGAGAAGTAGCATTCAGTAAAACCTCACAGGTCCTCTCCAAATGGGACCCTATCATCCTGAAGAACCAGCAGGCAGAGCAGCTGGTTTTTCCCCTGGGGAAGGAGCAGCCAGCCATTGCTCCCATTGAACATGCGCTCAGTGGCTGGAAGGCAAGAACTCCCCTGGAGCAGGAAATTTTTAACCTCCTCCATAAGAACAAGCAGCCAGTGACAGATCCTTTACTGACTCCCATGGAAAAGGCCTCTCTCCAAGCCATGAGCCTGGAAGAGGCAAAGATGCACCGAGCAGAGCTTCAGAGGGCTCGGGCTCTGCAGTCCTACTATGAGGCCAAGGCTCGAAAAGAGAAGAAAATCAAAAGTAAAAAGTATCACAAAGTCGTGAAGAAAGGAAAGGCCAAGAAAGCCTTAAAAGAGTTTGAGCAGCTACAGAAGGTTAATCCAACTGTGGCACTGGAAGAAATGGAAAAAATTGAAAATGCCAGAATGATGGAAAGAATGAGCCTTAAGCACCAAAACAGTGGGAAATGGGCCAAGTCAAAGGCAATTATGGCCAAATATGACCTGGAGGCTCGCCAAGCTATGCAGGAACAGTTGGCCAAGAACAAAGAACTGACACAGAAACTCCAGGTAGCCTCTGAGAGTGAGGAAGAGGAGGGAGGCACAGAAGTGGAAGAACTCCTTGTCCCTCATGTAGCGAATGAAGTGCAGATGAATGTGGACGGACCGAATCCCTGGATGTTCAGGAGCTGCACCAGTGACACCAAAGAGGCTGCAACACAGGAGGACCCTGAGCAAGTGCCAGAGCTTGCAGCTCATGAGGTTTCTGCAAGTGAGGCAGAAGAAAGACCAGTGGCAGAGGAAGAAATTTTGTTGAGAGAATTTGAGGAAAGGCAATCCCTTAGAAAAAGATCTGAGCTCAACCAGGATGCTGAGCCAGCAAGCAGTCAAGAAACAAAAGATTCTAGCAGCCAGGAGGTGCTGTCCGAATTGAGGGCACTATCTCAGAAATTGAAGGAAAAACATCAGTCCAGGAAGCAAAAAGCAAGTTCAGAGGGGACTGTTCCCCAGGTCCAGAGAGAGGAACCTGCCCCAGAAGAAGCGGAACCCCTATTGCTACAGAGGTCAGAGAGAGTACAAACTCTGGAAGAGCTAGAAGAGCTGGGAAAAGAAGATTGTTTTCAAAATAAGGAGCTTCCCAGACCTGTGTTAGAAGGACAGCAGTCAGAGAGGACCCCAAATAATCGGCCTGATGCCCCTAAGGAGAAGAAAGAGAAGGAGCAACTGATCAACCTACAGAACTTCCTGACCACACAGTCTCCTTCCGTGAGGTCTTTGGCAGTTCCCACAATAATgCTTTTGCTGGGGATGATGTCATCAGAGATTTCTTGAAAGAGAAGAGGGAAGCTGTGGAGGCGAGTAAGCCAAAGGACGTGGACCTGACACTACCTGGCTGGGGCGAGTGGGGTGGTGTGGGCCTAAAGCCCAGTGCCAAGAAAAGACGCCAGTTTCTCATTAAAGCCCCTGAGGGTCCTCCAAGAAAAGATAAGAATTTGCCAAATGTGATTATCAGTGAGAAGCGCAACATCCACGCAGCAGCTCATCAGGTACAAGTGCTTCCATATCCATTTACCCACCATCGGCAATTTGAAAGGACCATCCAGACCCCTATAGGATCCACATGGAACACCCAGAGGGCTTTCCAAAAGCTGACTACTCCCAAGGTCGTCACCAAGCCAGGCCATATCATTAAGCCCATAAAAGCAGAGGATGTGGGCTACCAGTCTTCCTCAAGGTCAGACCTGCCTGTCATACAGAGGAATCCAAAACGAATCACCACACGTCACAATAAAGAAGAAAAACTGTAGGTTGTGTAGCTGGAGAAGTGACAGTCAGGGGCCCTGATTCCACTTCCTTTGGTCCAGTTTTACTCTGCTACAGGGTGGATTCCAAAACTGGCTCAGCACATTGCATGTAGTTGAGCCACATTTT
>NM_006649.4
CCTTCGGCTTCCGTTCTTGGTCCATGTGAGAGAAGCTGGCTGCTGAAATGACTGCGAACCGGCTTGCAGAGAGCCTTCTGGCTTTGAGCCAACAGGAAGAACTAGCGGATTTGCCAAAAgactacctcttgagtgagagtgaagatgagGGGGACAATGATGGAGAGAGAAAGCATCAAAAGCTTCTGGAAGCAATCAGTTCCCTTGATGGAAAGAATAGGCGGAAATTGGCTGAGAGGTCTGAGGCTAGTCTGAAGGTGTCAGAGTTCAATGTCAGTTCTGAAGGATCAGGAGAAAAGCTGGTCCTTGCAGATCTGCTTGAGCCTGTTAAAACTTCATCTTCTTTGGCCACTGTGAAAAAGCAACTGAGTAGAGTCAAATCAAAGAAGACAGTGGAGTTACCTCTGAACAAAGAAGAGATTGAACGGATCCACAGAGAAGTAGCATTCAATAAAACCGCACAAGTCCTCTCCAAATGGGACCCTGTCGTCCTGAAGAACCGGCAGGCAGAGCAGCTGGTTTTTCCCCTGGAGAAAGAGGAGCCAGCCATTGCTCCCATTGAACATGTGCTCAGTGGCTGGAAGGCAAGAACTCCCCTGGAGCAGGAAATTTTCAACCTCCTCCATAAGAACAAGCAGCCAGTGACAGACCCTTTACTGACCCCTGTGGAAAAGGCCTCTCTCCGAGCCATGAGCCTAGAAGAGGCAAAGATGCGACGAGCAGAGCTTCAGAGGGCTCGGGCTCTGCAGTCCTACTATGAGGCCAAGGCTCGAAGAGAGAAGAAAATCAAAAGTAAAAAGTATCACAAAGTCGTGAAGAAAGGAAAGGCCAAGAAAGCCCTAAAAGAGTTTGAGCAGCTGCGGAAGGTTAATCCAGCTGCAGCACTAGAAGAACTGGAAAAAATTGAAAAGGCCAGAATGATGGAAAGAATGAGCCTTAAGCACCAAAACAGTGGGAAATGGGCCAAGTCAAAGGCAATTATGGCCAAATATGACCTGGAGGCTCGCCAAGCTATGCAGGAACAGTTGTCTAAGAACAAAGAACTGACACAGAAACTCCAGGTAGCCTCTGAGAGTGAGGAAGAGGAGGGAGGCACAGAAGATGTGGAAGAACTCCTTGTCCCTGATGTAGTGAATGAAGTGCAGATGAATGCAGATGGGCCGAATCCCTGGATGCTCAGGAGCTGCACCAGTGACACCAAAGAGGCTGCAACCCAGGAGGACCCTGAGCAACTGCCAGAGCTTGAGGCCCATGGAGTTTCTGAAAGTGAGGGAGAAGAAAGACCAGTGGCAGAAGAAGAAATTTTGTTGAGAGAATTTGAGGAAAGGCGATCCCTTAGAAAAAGATCTGAGCTCAGCCAAGATGCTGAGCCAGCAGGCAGTCAAGAAACAAAAGATTCTGGCAGCCAGGAGGTGCTGTCTGAATTGAGAGTACTATCTCAGAAATTGAAGGAAAACCATCAGTCCAGGAAGCAAAAAGCAAGTTCAGAGGGGACTATTCCCCAGGTCCAGAGAGAGGAACCTGCCCCAGAAGAAGAGGAGCCCCTGTTGCTACAGAGACCAGAGAGAGTACAGACGCTGGAAGAGCTAGAAGAGCTGGGAAAAGAAGAATGTTTTCAAAATAAGGAGCTTCCCAGACCTGTGTTAGAAGGGCAGCAGTCAGAGAGGACCCCAAATAATCGCCCTGATGCCCCTAAGGAGAAGAAAAAGAAGGAGCAAATGATCGACCTACAGAACCTCCTAACCACACAATCTCCCTCCGTGAAGTCTTTGGCAGTTCCCACAATAGAGGAGCTGGAAGATGAAGAGGAGAGAAACCATAGGCAGATGATAAAGGAAGCTTTTGCTGGGGATGATGTCATCAGAGATTTCTTGAAAGAGAAGAGGGAAGCTGTGGAGGCGAGTAAGCCAAAGGACGTGGACCTGACACTACCTGGCTGGGGCGAGTGGGGTGGTGTGGGCCTAAAGCCCAGTGCCAAGAAAAGACGCCGGTTTCTCATTAAAGCCCCTGAGGGTCCTCCAAGAAAAGATAAGAATTTGCCAAATGTGATTATCAATGAGAAGCGCAACATCCACGCAGCTGCTCATCAGGTACGAGTGCTTCCATATCCATTTACCCACCATTGGCAATTTGAAAGGACCATCCAGACCCCCATAGGATCCACATGGAACACCCAGAGGGCTTTCCAAAAGCTGACTACTCCCAAGGTCGTCACCAAGCCAGGCCATATCATTAACCCCATAAAAGCAGAAGACGTGGGCTACCGGTCTTCCTCAAGGTCGGACCTGTCTGTCATACAGAGGAATCCAAAACGAATCACCACACGTCACAAAAAACAGCTGAAGAAATGCTCTGTAGATTGAGTTGCTGGAGGAGTGACAGCCAGGAGCCCTGACTTCACTTCCTTTGGTCCAGTTTTACTCTGATACAGGGTGGATTCCAAAACTGGCTCAGTACATTGCATGTAGTTAAGCCACATTTTAAAAATAAAGGCATTTTTTAATCTA

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