Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RPP40P2
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:59262789-59263399  UCSC
Coordinates (T2T) chr13:58482603-58483213  UCSC
Coordinates (hg19) chr13:59836923-59837533  UCSC
Strand +
Parental Sequence NM_006638.4
Parental seq. overlap 509 bp
Parental seq. overlap (%) 34.1%
Genomic Region Intergenic
Retrocopy Summary RPP40P2, located on chr13:59262789-59263399, is a retrocopy of the parental gene RPP40. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RPP40
Full Name ribonuclease P/MRP subunit p40
Also known as RNASEP1|bA428J1.3
Coordinate chr6:4993554-5004058
Strand -
Gene summary Enables ribonuclease P RNA binding activity. Contributes to ribonuclease P activity. Involved in tRNA 5'-leader removal. Part of multimeric ribonuclease P complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RPP40P1
Bonobo Pan paniscus RPP40P1
Gorilla Gorilla gorilla RPP40P1
Orangutan Pongo abelii RPP40P1
Gibbon Nomascus leucogenys RPP40P1
Green monkey Chlorocebus sabaeus RPP40P1
Crab-eating macaque Macaca fascicularis RPP40P1
Rhesus Macaca mulatta RPP40P1
Baboon Papio anubis RPP40P1
Golden snub-nosed monkey Rhinopithecus roxellana RPP40P1
Mouse lemur Microcebus murinus RPP40P1
Marmoset Callithrix jacchus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RPP40P2
TTGCACTAAAATGCAATGCAAATATTAATGAAGATAATATTACTGCCCAGGTATGAAACAGAAAAATAATTTTATCACTGGATAAAGACATGAAAAAACTAGACTTCAAGGACATCCACCTGAGTATTCTGGCAGAAAATCATGAAATTTAGTGTTTTCATTGATTTGATAGGCTTATCCTTTAACCCAGATTCTAAGACATATGAAAGGACGTCTTGGCTCTCCAAGGAAAAGAAGCCATTGAAATTTGGTTTTCTTTTGGCTTGGCATTATACAAAAACAATGGGCCTAATAATTTCATATCAACTCAGTGCTACCCTCAGCCAAGGACGGTGGTGGCAAAGAATCCTTGTATACAATCACTGGTTGCATATTTCCAGAGAGGATCTGTCTCCTAATGGAACAGCTAGCTCACTACTCTGATTAAACAAAGTTAGTTCCTCAGATTACATTGTCAGTTCAAGACTTTGCAGACAGCCCTGTTTCATAAAGAGAAAATGAATATTATTTTTAAAAAAGAGAAACATTTTTACAACTTTGTAATTTTTAATAATCAGGACTATTGGCTTCAGAAGGCTATTGGGGCAAATAATGACTGTCCACCATCAAAA
>NM_006638.4
AGCGGAGGCCGGGAGGACCAGGAACCCAGGAGAGCATGGCCACGCTGCGCCGGCTTCGGGAGGCGCCGCGGCACTTACTGGTTTGCGAGAAATCCAACTTCGGCAACCACAAGTCGCGCCACCGGCATCTTGTGCAGACGCACTACTATAACTACAGGGTTTCATTTCTCATTCCTGAATGTGGGATACTATCGGAAGAACTGAAAAACCTGGTCATGAACACTGGACCCTATTACTTTGTGAAGAATTTACCTCTTCATGAATTAATTACACCTGAATTCATCAGTACCTTTATAAAGAAAGGTTCTTGCTATGCACTAACATACAATACACATATTGATGAAGATAATACTGTTGCCCTGCTACCAAATGGGAAATTAATTTTGTCACTGGATAAAGACACTTATGAAGAAACTGGACTTCAGGGTCATCCATCTCAGTTTTCTGGCAGAAAAATTATGAAATTTATTGTTTCCATTGATTTGATGGAATTATCCTTAAACTTGGATTCTAAGAAGTATGAAAGAATATCTTGGTCTTTCAAAGAAAAGAAGCCATTGAAATTTGATTTTCTTTTGGCTTGGCATAAAACAGGTTCAGAAGAATCGACAATGATGTCATATTTTTCCAAGTACCAAATTCAGGAGCATCAGCCAAAAGTAGCACTGAGCACGTTGAGAGATCTCCAGTGCCCAGTGCTGCAGAGCAGCGAGCTGGAGGGAACGCCAGAGGTGTCCTGCCGGGCTCTGGAGCTCTTCGACTGGCTCGGCGCCGTCTTCAGTAATGTCGACCTAAATAATGAGCCTAATAATTTCATATCAACCTATTGCTGTCCTGAGCCAAGCACAGTGGTGGCAAAAGCTTATTTGTGTACAATCACTGGCTTCATACTTCCAGAGAAGATCTGTCTCCTATTGGAACATCTCTGTCACTACTTTGATGAACCGAAGTTAGCTCCATGGGTTACACTGTCCGTTCAAGGCTTTGCAGACAGCCCTGTTTCTTGGGAAAAAAATGAACATGGTTTTCGAAAAGGAGGAGAACATTTATATAACTTTGTGATTTTTAATAATCAGGACTATTGGCTTCAGATGGCTGTTGGGGCAAATGATCACTGTCCACCATAAAAAATAAAAATTAAAAATCGTGTTTACTTACATTTACGCTTGCTTTCAGATTTCTTAATGGTAAAAGGTCTGTGTGTCCACTCAGGCTTGTGTGATGGTGACATTTCTCAGATCAGCATTTGCTGGCATCCTGCCCTGCACCTGAGACCCATCTGTGATGGCAGCAAGGCCTGCTGTCCAGTGAATAGCTCATAGTTGATTTCTCTCTGTCAACATAAGCACAGGGTTGTGGGTTACTATGTGGTACACTGGGCCAGGATGTCCAGGGACCGGGGATATTGGTCCCCATCTCACTCCATTGGTTGAGATATATTTTGTTCATTACAACTTTTTCAGATAATAAAAAGAAATCTCATCctta

Publications

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