Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name PPP1R2P10
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr3). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:63810351-63811897  UCSC
Coordinates (T2T) chr13:63031929-63033475  UCSC
Coordinates (hg19) chr13:64384484-64386030  UCSC
Strand -
Parental Sequence NM_006241.8
Parental seq. overlap 1383 bp
Parental seq. overlap (%) 40.7%
Genomic Region Intergenic
Retrocopy Summary PPP1R2P10, located on chr13:63810351-63811897, is a retrocopy of the parental gene PPP1R2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PPP1R2
Full Name protein phosphatase 1 regulatory inhibitor subunit 2
Also known as IPP-2|IPP2|PPP1R2A
Coordinate chr3:195514428-195543348
Strand -
Gene summary Protein phosphatase-1 (PP1) is one of the main eukaryotic serine/threonine phosphatases. The protein encoded by this gene binds to the catalytic subunit of PP1, strongly inhibiting its activity. Ten related pseudogenes have been found throughout the human genome. Several splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla PPP1R2P5
Gibbon Nomascus leucogenys PPP1R2P2
Golden snub-nosed monkey Rhinopithecus roxellana PPP1R2P5
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PPP1R2P10
GCGTCGCTCCGGAGCTGGAGCTCTTGCCGGCGTCTCCCCGCGAGCAGCGGCTGAAGTGCTGGCGGCTAAGAGCCCGTGAGCAGCCGCCACTCCTTCGGCGTTGGCTCTTGCGCCGGGGTCGTTGTTTCGTGACAACCACCCAGGTAGCCGTTTCTGAGACGGCAGATGCGGCCGCTTTAGCCCTGAGCGGGCTCCGCGCCTCCCTGGACGGTCTCTGCCAGTGCCCGACTCTTCTCTTCCGGACTCCACGCCAAGCAGCGACCCTGAGCCAACAGACAGAGCGCCCAGAAATGGCGGCCTGGACTGCCTCGCACTGGCCAGTGAAGGGGATCCTGAAGAACAAGGCCTCTACAGCTTCCTCTATGGTGGCCTCGGCTGAACAGCCCAGCGGGAGTGTCGAGGAGGAGCTGAGCAAAAAATCCCAGAAGTGGGAAGAAATGAACATCCTGGCGACATATCATCCAGCGGACAAAGACTATGGTTTAATGAAAATAGATGAACCAAGCACTCCTTACTGTCGTAAGATGGGTGATGGTGAAGATGCGTGTAGTGATACAGAAACCACTGAAGCCGTGGCACCAGATATCTTAGCTAAGAAATTAGCTGTTGCTGAAGGCTTGAACCCAAAGTATCGGGTTCAGGAACAAGAAAGCAGTGGAGAGGAGGCTAGGACCTCTCACCTGAAGAACGAGAAAAAAGGCGACAATTTGAAATGAAAAGGAAGCTTCACTACAATGAAGGACTGAATATCAAACTAGCTAGAGAATTAATTTGAAAAGACCTACATGATGACAAAGATGAAGAAATGTTAAAGACTGCAGATGGAGAAAGCATGAAGACGGAACAATCAAATCAAAGCTCTACAGCAAGTGACCAACGGCAAAACACATTCAGTAAGTTCATAGAAGAGCTTTGTTCAACACTGCAACTGTTTGCTAGATATAAACCCTGTTACTATAATACATTGCTTCTTGATCTCCACAATTTATGATTTAAGTATCAAAATCATACCAGTTATTATATATTACCAAGAATTAAATGATATCCTTAGAAACTGATTAGACTGAAAATGCCTAATTGGTATATATATCTTGTGCCTAGTACTTTACCACAAATACAGTGTAATATCATCAGTCCAAAACTGCATTACTTTTGTAAAAACACTGGTTAATTTGTGTAAGATATTATATAGCATTTTTAAAGGATAAAAAATATCTTTGGGGAGGAGAACTAAGTTATTTTCATCACTCTAAATGGGGCGATACCTCTTATAAGTTTGTTGGTTTGCTTTTTTTTAAAATCAAAAGACAATTGAACAACAGGATGTATAGGCTGATAAATATTCAGGCCGAATAGTATTTTAACACTTGTCTTCAACTTGATTTGTCTGTTTAATTGAAAAGGATTATAAGAGTTACTCTTGCATTTTCTGTCCTACTACCTTTAAAGTTACTGTTGAGTTTCTTTGTATTTACAAGGAAAGGACTGAACTTTTTCTCATCAAAACTAGCCTTTTTTCTCACAAATAAATTATCAGTTTAAACTTG
>NM_006241.8
GCTTCGGCGTCGCGTCGCTCCTGCGCTGGAGCTCTAGGCCGGCGTCTCTCCGCGAGCCGCGGGTCAAGTGCCAGTGGCTAAGGGTGCGCGAGTAGCCGCCACCCGTTCGGCGTTGGCTCTGGCGTCGGGGTCGTTGTGTCGTGACAACCGCTGCGGTAGCCGTTTCCGAGGCAGCAGTTGCGGCCGCTTTAGCCCTGAGCGGGATCTGCGGCTGCCTGCGAGTCTCTGCTGTGCCGACCCTTCTCTTCGCGGACCCCACGCCAAGCAGCGACCCTGAGCCGACAGCCGGAGCGCCCGGCAATGGCGGCCTCGACGGCCTCGCACCGGCCCATCAAGGGGATCTTGAAGAACAAGACCTCTACGACTTCCTCTATGGTGGCGTCGGCCGAACAGCCCCGCGGGAATGTCGACGAGGAGCTGAGCAAAAAATCCCAGAAGTGGGATGAAATGAACATCTTGGCGACGTATCATCCAGCAGACAAAGACTATGGTTTAATGAAAATAGATGAACCAAGCACTCCTTACCATAGTATGATGGGGGATGATGAAGATGCCTGTAGTGACACCGAGGCCACTGAAGCCATGGCGCCAGACATCTTAGCCAGGAAATTAGCTGCAGCTGAAGGCTTGGAGCCAAAGTATCGGATTCAGGAACAAGAAAGCAGTGGAGAGGAGGATAGTGACCTCTCACCTGAAGAACGAGAAAAAAAGCGACAATTTGAAATGAAAAGGAAGCTTCACTACAATGAAGGACTCAATATCAAACTAGCCAGACAATTAATTTCAAAAGACCTACatgatgatgatgaagatgaagaaatgttagagactgcagatggagaaagcatgaatacggaagaatcaaatcaagGATCTACTCCAAGTGACCAACAGCAAAACAAATTACGAAGTTCATAGACGAGATTTGTTCAACACTGCAATTGTTTGTTAGATGTAAACCCTGTGACTATAGTACGTTGCTTCTTGTTCTTCACAATTCATGACTTAAGTACCAAAATGCATACCAGTTATTATATATTGCCAAGAATTAAATGATAAACTTAGAGACTGATTAGACTGAAAATGCCTAATCGATATATATATTCTTGTGCCTAGTACTTTACCACAAATACAGTGTAATATCATCAGTCCAAAACTGCATTACTTTTGTAAAAACACTGGTTAATTTGTATAAGATATTATAGAGCTTTTTATGCTTTAGAAGTTAAACAATATCTTTGGGGGGGAACTAATTTATTTTCATCACTTGAAATGTGGTAGCTCTTACAAAGTTTATTGATTTGATTTTTTTAAAAATCAAAAGCCAATTGAACAACAGGATATATAGACTGATAAATATTTAGGCTGAATAGTATTTTAACACTTGTCTTCAACTTGATTTGTCTGTTTAATTGAAAAGAATTATAAGAGTTACTGTTGCATTTTCTGACCTACTATTTTTAAAATTCCTGTTGAGTTTCTTTGTGTTTACAAGGAAAGGACTGAACTTTTTCTCATCAAAACTAGCTTTTTTCCCCACAAATAAATTATCAGGTTAAACTTTCACCAATGTCTGCTCTGTTTTTTGTTTTTGGGGGGTTTTTGTTTGTTTTTGTTTTTTAATGTTTTTGGTACACTGGGCAGACTTCAGAGCAGTTTTTTAAAAAAATAAATATTCTAATGTAGCTATCTCGCCATTCCCTTTAAATACCTGTCTTAACCTCCTGCTTTTCTTTCCTACTCCTTTCCACACATACGCACACAATCTTCTACCTTTTAAAGGATCATTAAGACTGTCACCACATTAGGAGCTCTTTCTCTCACTCTTCTGTCATTTGCTGCTATGTTGAAATTCTTATTTTGACCATCAATGCCTATGAATTCTTCTAATACGTGAAGAAAATAGTTTGAGTAGCAGCAGTGCTATAGGTGGGAAATACAGTTTAGCTGCTGAATTTCTATACCTCTCTGATTTACAGATTGCTAATTAAATGGCTATTATTAGTTTGGATTAATTAGACTTAAGAAAACAACTAACTGAGGGTTTTTTTTGTTTGTTTTTTGAGGGTTTTCTTTGCATGAGAATTGTATGTAACCAGTGATATGATTATTCCTGAATGTACAGACAGAAGTAAGCCTGGACATTGTTAAATAGTCCCTGCTTTAAGGGACTACGATAATGTGTACTATGACAAACGTGCTTTATTCTTCTAACGCAGTAAGAATTAGGTGGAATTTTTTCCTTCAACCAAGTGCAGGAAAGCCCTGTGTGTCTTGGTTTAGTTATGGTTTCATTTCTAGCCATACAATTGATGAATTGTGTACAACTTTTGTTAGTACCAAAATAATCTGTTATATGAACAGACTTCTAAAATAACGTCTGTATATTTTATATATAGATACATATATGAAAGAAGGCTTTTATTGAACAGCTTATCTTCCACTTGCAGGTTTATGGAAACAGCAGTATTTGAAAATAAATAAAAAGTGGGAGAATTCCTTGCTGTTAGAAGAATGTGGCCATTATTTTGATTTTTTGAATGAGATATATAATCAAAGTACTGCTGAACTGTGAGTGCAGTATTCTAAACATTTCAGCTAGGAATACCACTGATTTAGAAACAAAACTGTTTGTCTCTGGTTTCTGAATTTAAAATGTTGGGATTACCTGTTTAAATCTGTCTTGGGGGATGTAGAGATTAAGTCTGTACATGTGCGTGCACATATATTCATGCACCCTCTGATTTTGGTTTTCTTGTTTCTGAGTTCTTAGAAAGTACCCACATACTCTTTTTTTTTTTTTGTAGAAGTAGCTGTCATAGAGTGAAGAAAAGGATAAGACTTTAAACAGTTGATTCTTTTTGTGTTTTCTACAAACTATTTTTTGAAATTTAAATCACAAACTCATTTTCTGGTTTTTAGAAAGTAGATGATGATTTCAGAGGAGTAAGGCATGCCAAGCAGCATGCTCAGTGGGGTTTTAGGCTGTCACATGCAGCTGAGAAAAGGTATGTTCAAGTCATAAGTAGGTAATTGATAGGGTATGAACTAGTCAAAATATGAACCATTATGATTCAAGTTAGATTTTCCTCTGGAGAGACAGATCTGAATGTTCAGTTCTAGCCAAGGTAGATTTTACTTTCAACTTTTTAATCAGTATCACTTTCTGTGCTTAACTATTTGGTGTTACCTTGTCTGTTTTCATTTGTCTAAAATTCTGCAGAGATGACTAAAATTTGACATAATGGTGTAAATGGATTGTTAAGGTAACTTTCAGTTGAAGATTAAAGCAAGATGCCATTTTCCCCATGACTTTGGTTTTGTTTACATTTTTCCCTTTCAGTTAGTATACACTACACGTACTGTAATAAAATACAATAATATGA

Publications

PMID - Link Title