Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name STARP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr13:65309226-65310984  UCSC
Coordinates (hg19) chr13:65883358-65885116  UCSC
Strand -
Parental Sequence NM_000349.3
Parental seq. overlap 1338 bp
Parental seq. overlap (%) 51%
Genomic Region Intergenic
Retrocopy Summary STARP1, located on chr13:65309226-65310984, is a retrocopy of the parental gene STAR. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name STAR
Full Name steroidogenic acute regulatory protein
Also known as STARD1
Coordinate chr8:38142700-38150952
Strand -
Gene summary The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes STARP1
Bonobo Pan paniscus STARP1
Gorilla Gorilla gorilla STARP1
Orangutan Pongo abelii STARP1
Gibbon Nomascus leucogenys STARP1
Green monkey Chlorocebus sabaeus STARP1
Crab-eating macaque Macaca fascicularis STARP1
Rhesus Macaca mulatta STARP1
Baboon Papio anubis STARP1
Golden snub-nosed monkey Rhinopithecus roxellana STARP1
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>STARP1
GGCGGGCGGGGAAGACTCTCTACAGTGACCAGGAGCTGACCTATCTCCAGCAGTGGGGAGGAGGCCATGCAGAAGGCCTTGGGCATCCTTAGCCCTCGGCAACTACGAGGGCTGGAAGAAGGAGAGCCAGCAGGACAATGGGGATAAAGTGATGAGTAAAGTGGTTCCAGATGGGGCAAGGTGTTCCGGCTGGAAGTCGTGGTGGACCAGCCCATGGAGAGGCTCTACAAAGAGCTCGTGGAGTGCATGGAGGCAATGGGGGAGTGCAACTCCAATATCAAGGCGATCAAGGTCTTGCAGAAGATGATCAGAAAAGATACATTCATTGCCCATGAGCTGGCTGCAGAGGCAGCAGGAAACCTAGTGGGGCCTTGTGACTCTGTGAGCATGTGCTGTGCCAAGCGTCAAGGCTCCACCTGTGTGCTGGCTGGCATGGCCACAGACTTCGGGAACATGCCCGAGCAGAAGGGTGTCATCAGGGGGAGCATGGTCCCACTTGCATGGTGCTTCACCTGGTGACTGGAAGTCCCTCCAAGACCAAACTTACATGACTGCTCAGCATCGACCTCAAGGGGTGGCTTCCCAAGAGCATCATCAACCAGGTCCTGTCCCAGACCCAGGTGGATTTTGCCAACCACCTGCACAAGCGCCTGGAGTCCCACCCTGCCTCTGAAGCCAGGTGTTGAAGGCCAGCCTGCTGTTCCCAAGTGTGTCCAGCTGCACTGCTACACACGCTTATCAGGAGAATCCTTGCTGGAAGCCTGCAAGCTTAAAATCTCCATCTGGCGACAGAGGAATAGGTGGGGTTAGTGTATAGAGTATGATACTAGGATTCAGACTGGTAAAAGTTTTTAGTACCAAGAAAACAAGGATGAGGCTCTTTGATTAAAAGGTAACTTCATTCACTGACTAGCTATGACATGAAGGTTGAGGATCCTAAAATAATTGTAAAACTTTTTTTCTGGGCCTTTATGTGCCCACCTAAAACCATCTTTAAAATGCTAGTGGCTGATATGTGTGGGGGGATGCTAGTCACAGGGCCTGAGGAGTCTTGCTTTATGGGCTGGAGAACCCCATGCCCTGAAGGCAGAGCATGTGCACAAAGCAGAATCTTAGAGGGTCTCCTGCAGCCCTCCACTCCTCCAAGTCGCTGCATGGCAACACCAGATAACAAGCAGCACCCCACAGTGGGTACCTTCCAGAAATATAGTCCAAGCTTTCTCTATGGAAAAAGACAAAACTAATTAGTAAATAGGTTTCCCTATTGAGTCCATAGGCACCAGTCAGAAAAAAGAATCATAATTCCCCACCACTGCCACATCTGCCAGGAAAGAATGCTGCTAGCGACATTCAAACTGTGCTCCAGGAGCTCCTACAGACACATGCGCAACATGAAGGGGCTGAGGCAACAGGCTGTGAGGGGGCATCGGGCAGGAGCTTAACCGGAGGGCCCTGGGGGCCCCACCCCAAGCGCTTGGATTAACCAGGTTCCGCGGCGGAGCTCTCTGCTTCGTTCTCTGCTGGAAGAGACTCTCTACc
>NM_000349.3
GCAGCTGCGGGACTCAGAGGCGAAGCTTGAGGGGCTCAGGAAGGACGAAGAACCACCCTTGAGAGAAGAGgcagcagcagcggcggcagcagcagcggcagcGACCCCACCACTGCCACATTTGCCAGGAAACAATGCTGCTAGCGACATTCAAGCTGTGCGCTGGGAGCTCCTACAGACACATGCGCAACATGAAGGGGCTGAGGCAACAGGCTGTGATGGCCATCAGCCAGGAGCTGAACCGGAGGGCCCTGGGGGGCCCCACCCCTAGCACGTGGATTAACCAGGTTCGGCGGCGGAGCTCTCTACTCGGTTCTCGGCTGGAAGAGACTCTCTACAGTGACCAGGAGCTGGCCTATCTCCAGCAGGGGGAGGAGGCCATGCAGAAGGCCTTGGGCATCCTTAGCAACCAAGAGGGCTGGAAGAAGGAGAGTCAGCAGGACAATGGGGACAAAGTGATGAGTAAAGTGGTCCCAGATGTGGGCAAGGTGTTCCGGCTGGAGGTCGTGGTGGACCAGCCCATGGAGAGGCTCTATGAAGAGCTCGTGGAGCGCATGGAAGCAATGGGGGAGTGGAACCCCAATGTCAAGGAGATCAAGGTCCTGCAGAAGATCGGAAAAGATACATTCATTACTCACGAGCTGGCTGCCGAGGCAGCAGGAAACCTGGTGGGGCCCCGTGACTTTGTGAGCGTGCGCTGTGCCAAGCGCCGAGGCTCCACCTGTGTGCTGGCTGGCATGGCCACAGACTTCGGGAACATGCCTGAGCAGAAGGGTGTCATCAGGGCGGAGCACGGTCCCACTTGCATGGTGCTTCACCCGTTGGCTGGAAGTCCCTCTAAGACCAAACTTACGTGGCTACTCAGCATCGACCTCAAGGGGTGGCTGCCCAAGAGCATCATCAACCAGGTCCTGTCCCAGACCCAGGTGGATTTTGCCAACCACCTGCGCAAGCGCCTGGAGTCCCACCCTGCCTCTGAAGCCAGGTGTTGAAGACCAGCCTGCTGTTCCCAACTGTGCCCAGCTGCACTGGTACACACGCTCATCAGGAGAATCCCTACTGGAAGCCTGCAAGTCTAAGATCTCCATCTGGTGACAGTGGGATGGGTGGGGTTCGTGTTTAGAGTATGACACTAGGATTCAGATTGGTGAAAGTTTTTAGTACCAAGAAAACAGGGATGAGGCTCTTGGATTAAAAGGTAACTTCATTCACTGATTAGCTATGACATGAGGGTTCAGGCCCCTAAAATAATTGTAAAACTTTTTTTCTGGGCCCTTATGTACCCACCTAAAACCATCTTTAAAATGCTAGTGGCTGATATGGGTGTGGGGGATGCTAACCACAGGGCCTGAGAAGTCTTGCTTTATGGGCTCAAGAATGCCATGCGCTGGCAGTACATGTGCACAAAGCAGAATCTCAGAGGGTCTCCTGCAGCCCTCTGCTCCTCCCGGCCGCTGCACAGCAACACCACAGAACAAGCAGCACCCCACAGTGGGTGCCTTCCAGAAATATAGTCCAAGCTTTCTCTGTGGAAAAAGACAAAACTCATTAGTAGACATGTTTCCCTATTGCTTTCATAGGCACCAGTCAGAATAAAGAATCATAATTCACACAAACATCAGTCTTTGTTTTAATATTGTACTGTTAAAAAAATCTATGCAgctgggtgcagtggctcacgcctgtaatcccagcattttgggaggctgaggtaggcggatcacaaggtcaggagatcgagaccatcctggccaacatggtgaaaccccgtctctactaaaatacaaaaaattagctgggtgtggtggcgcaaacctgtagtcgtagctacttgggaggctgaggcaggggaatcacttgaaccccggaggcggaggttgtagtgggccgagattgtgccactgcgctccagcgtgggcgacagagtgagactccatctcaaaaaaaaaaaaaaaaaaaTCTATGCTAGTAGATTACAACTTCACACTAGAGGAGTTCTGGACAAAGCTTTTAATTAGTCAAACTAAATTAAGGCTCATTAAAAGGAAAGGAACTACTGGGAAATTATGCAATTCAATAATTTAGACTCTGTTACCAGGATCTTTCATAAAAATTTAATTTCCATAATCATAACCTAAATGAGTTCTTAAAGAATTCTATAAGCAATAGCTGATTAATGGGCCCTGGAAGATGAAGATTATAACTGTTTATTTACCTAATTAAAAGGAAAGGCAGTGCCAAATATGAGAGGATAAACAATATTAGTTAACATTTCTGTTATTTATGATGCCAATTAGTAGTAAGATAATTCCACAGCTGTCAACTTTGTTTGGGGCTGGCAACTTCTCTGCTTAAACAGGCTAAAAGTTTAGTATTCTGGGAGAAGTGGCTGGAAGAAGGGGTAATATGGTGAAAGCAAATTCCCTTTCCCAGGAGTCAAGAGAATTTATGTGAggtggctcccgcctgtaatctcagcactttgggaggccaaggcaggcaatcacctgagggcaggagaccagcctgactaacatggagaaaccccatctctactaaaaatac

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